Volume 2, Issue 6 (Spring 1999)
J Arak Uni Med Sci 1999, 2(6): 36-40 |
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Hashemieh M. Incidence of Diabetes Mellitus Among Thalassemia Patients in Arak City. J Arak Uni Med Sci 1999; 2 (6) :36-40
URL: http://jams.arakmu.ac.ir/article-1-6577-en.html
URL: http://jams.arakmu.ac.ir/article-1-6577-en.html
Arak University of Medical Sciences, Arak, Iran.
Abstract: (1282 Views)
Major thalassemia is the most prevalent hemoglobinopathy in the world.one of the accidents of this disease is endocrinopathy due to hemosiderosis. This study was performed on 50 thalassemic patients in arak city in order to aeeesss the incidence of diabetes mellitus among these patients. Fasting blood sugar and oral glucose tolerance test were requested for all patients. The mean age was 11 and 48% of patients were in the range of 5-9 years old. 52% of patients were female and 48% of them were male. 10% of patients had positive family history. 8% of patients had overt diabetes mellitus and 4% of them had impaired oral glucose tolerance test. Among four diabetes patients three of them had received transfusion for more than 10 years. There was a significant relationship between the incidence of diabetes mellitus and duration of transfusion (p<0.001). In 56% of patients the level of ferritin was above 1000mg/lit. Among 4 diabetes patients, in 3 of them the level of ferritin was above 1000mg/lit. There is a significant relationship between diabetes mellitus and ferritin level(p=0.025). Insulin usage can control blood sugar level in diabetes thalassemic patients.
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