Abstract
Background: The present study aims to provide a comparative analysis of studies on Acceptance-Commitment and Cognitive-Behavioral interferences effectiveness on generalized Anxiety disorder.
Materials and Methods: This is a quasi-experimental research. Students at the Islamic Azad University of Toyserkan, Iran, who have been in contact with the counseling office in the educational year 2016-2017, were selected as statistical population. These students, in a diagnostic interview with a psychiatrist, met the DSM5 standards for generalized anxiety disorder and were approved by a trusted psychiatrist. Then, these selected subjects gave average or more score in beck anxiety test and were randomly divided into two groups of 20. After executing interferences for each group, data were analyzed by t-test and covariance.
Results: The findings indicated that the average acceptance and commitment interference was 12.3 (t= 16.01 and p < 0.001) and the average cognitive-behavioral interference was 11.25 (t= 10.60 and p < 0.001) on generalized anxiety disorder. Also, covariance analysis showed that ACT was more effective than CBT and f (0.03) was significant. Therefore, all hypotheses turned out to be approved.
Conclusion: The research demonstrated that both interferences are effective in treating generalized anxiety disorder, although Acceptance and Commitment interference is more effective than Cognitive and Behavioral interference.
 

Background and Aim There is a high correlation between depression and anxiety in children which are also related to laterality. This study aimed to compare generalized anxiety and social anxiety in sinistral and dextral children with depression symptoms. 
Methods & Materials This is a cross-sectional study with a causal-comparative design. The study population consisted of all primary students (fourth to sixth grade) of Arak Province in Iran. A convenience sampling method was used to select study samples. Prior to study, following questionnaires were completed: Children's Depression Inventory, Brief Scale of Generalized Anxiety Disorder, and Liebowitz Social Anxiety Scale for Children and Adolescents. Then, those with depression score of 19 and higher were assigned into two groups of sinistral (n=31) and dextral (n=35), and compared in terms of generalized anxiety and social anxiety.
Ethical Considerations This study obtained its ethical approval form the Research Ethics Committee of Arak University of Medical Sciences (code: IR.ARAKMU.REC.1397.298). 
Results The results of multivariate analysis of variance showed a significant difference in two study varia-bles between groups (P=0.001). Moreover, based on the results of univariate analysis of variance, sinistral children had higher generalized anxiety compared to dextral children; however, they were not significantly different in terms of social anxiety.
Conclusion Considering the higher vulnerability of depressed sinistral children to anxiety disorders, they are more likely to need specific ways of preventing and treating depression and generalized anxiety disorder. 

Background and Aim Various research studies have investigated the relationship between anxiety and worry. The present study aimed to examine the mediating role of cognitive emotion regulation and mindfulness in the relationship between anxiety and worry.
Methods & Materials The present study follows a correlational design study. The research sample included 248 students of Kashan universities in Iran studying in the 2017-2018 academic year. The study data were collected using the generalized anxiety disorder (GAD-7), Pennsylvania state worry questionnaire (PSWQ), the Persian short form of cognitive emotion regulation questionnaire (CERQ-P-short form), and five-factor mindfulness questionnaire (FFMQ). Then, the obtained data were analyzed using the SPSS v. 22 and AMOS v. 22 software.
Ethical Considerations The Ethics Committee of Kashan University of Medical Sciences approved the study (Code: IR.KAUMS.REC.1396.36).
Results The results showed a significant relationship between generalized anxiety and worry, worry and cognitive emotion regulation, worry and mindfulness, generalized anxiety and cognitive emotion regulation, and anxiety and mindfulness. The results of the structural equation modeling confirmed the mediating role of cognitive emotion regulation in the relationship between anxiety and worry. Also, the path coefficient of mindfulness and anxiety was removed from the model because it was not significant.
Conclusion Generally, cognitive emotion regulation plays a mediating role in the relationship between anxiety and worry. These findings seem applicable in the individual, family, educational, therapeutic, and interpersonal mental health fields.

Introduction: Generalized anxiety disorder can be described as a debilitating disorder characterized by negative evaluation by others, internal shame, negative self-concept, as well as high levels of anxiety and avoidance in specific social and functional situations. The purpose of this study was to investigate the effective of hypnotherapy in promotion subjective well-being and sleep quality in people with generalized anxiety disorder.
Methods: This was a quasi-experimental study with pretest-posttest and a control group design and conducted on 40 persons who had generalized anxiety disorder in Rasht, Iran in 2023 and were randomly divided into two experimental and control groups (20 persons in each group). The hypnotherapy was conducted during 6 sessions in the experimental group, while the control group did not receive any treatment. The data were collected through the subjective well-being and sleep quality Inventory. Multivariate analysis of covariance was used to analyze the data. This study was approved by the Research Ethics Committee of Payame Noor University (Code: IR.PNU.REC.1402.070).
Results: The results indicated that hypnotherapy was effective on subjective well-being (F= 33.38, P=0.001) and sleep quality (F= 5.10, P=0.03) in people with generalized anxiety disorder; this method also increased their subjective well-being and sleep quality.
Conclusions: The based on the results of the present study, hypnotherapy is effective in promotion subjective well-being and sleep quality in people with generalized anxiety disorder. It suggests that these method are used along with other psychological and pharmaceutical therapies for people with generalized anxiety disorder as a clinical intervention. 

Introduction: This research aimed to investigate the effectiveness of combined treatment based on virtual reality and mindfulness on cortisol levels in individuals with generalized anxiety disorder. 
Methods: The study employed a semi-experimental design with a pre-test-post-test control group and a two-month follow-up period. The study population included all individuals with symptoms of generalized anxiety disorder who referred to the clinics of the Psychological Services Center and Counseling in Region 3, the Counseling and Psychological Services Center of Welfare in Region 6, and the Aryaz Counseling and Psychological Services of Region 6, Tehran, from April 2022 to the end of autumn 2022.
Results: The sample consisted of 30 individuals (10 males and 20 females) with generalized anxiety disorder, selected purposefully and randomly assigned to a treatment group based on virtual reality and mindfulness (15 individuals) and a control group (15 individuals). Pre-test, post-test, and follow-up cortisol levels were measured, and the Generalized Anxiety Disorder 7-item scale (GAD-7) was used as the entry criterion. Subsequently, the experimental group received an eight-session, 17-minute weekly treatment based on virtual reality and mindfulness. Participants in this group, while immersed in a virtual environment, watched 360-degree virtual reality videos, "Walking by the Beach" and "Pebbles in the Lake," accompanied by mindfulness audio contemplation, "Being Present and Breathing," and "Wise Mind," using a VR headset and VR-ARBOX. The control group received no treatment.
Conclusions: After completing the interventions, post-tests and two-month follow-ups were conducted. The data were analyzed using repeated measures analysis of variance (ANOVA) with SPSS23 software, revealing that the combined treatment based on virtual reality and mindfulness was effective in reducing cortisol levels. It is suggested that this combined method is used as a clinical intervention in order to reduce the level of anxiety and cortisol of people suffering from generalized anxiety disorder alone or along with other psychological and pharmaceutical interventions.

Introduction: A woman due to menstruation, pregnancy and poor iron intake and absorption it is prone to iron deficiency anemia and its effects. The aim of this study was to investigate the effectiveness of process-based treatment on anxiety in women suffering from iron deficiency anemia and generalized anxiety disorder.
Methods: It was performed by utilizing a single-case experimental design. In doing this, six female participants suffering from iron deficiency anemia were selected through purposive sampling and placed under the individual process-based therapy during nine 60-minute sessions. In the pre-treatment stage, the participants responded to Newman, Zueling, Kachin and Constantino's fourth version of the generalized anxiety disorder questionnaire and underwent clinical interviews. They also completed the Beck's depression inventory in the baseline stages and third, sixth and ninth sessions of the intervention and finally at the 3-month follow up stages. The data were analyzed by the method of visual analysis, stable change index and recovery percentage formula, and the effectiveness of the treatment was evaluated using the Ingram criteria.
Results: The results showed that the percentage of overall recovery in depression for the first to sixth participants in the intervention stage was 49/26، 50/54، 59/27, 76/20، 54/41 و 57/83 and in the follow-up stages was 70/10، 64/70، 75/93، 78/61، 77/57 و 84/93; respectively. Also, the percentage of overall recovery in the intervention and follow-up stages was 57/90 and 75/30; respectively indicating to a success in therapy.
Conclusions: Process-based therapy reduces depression of the research participants and it is suggested to be used as a method of treatment and complementary to medical treatment to remedy comorbid mental disorders and improve the general performance of people with anemia.