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Showing 3 results for General Anesthesia

Afsane Norouzi, Shirin Pazoki, Mina Darabi,
Volume 10, Issue 2 (6-2007)
Abstract

Introduction: Type of anesthesia is important in the maternal and fetal well being. There are different informations about effect of general and spinal anesthesia on Apgar score, so in this study a comparision was made on Apgar scores of neonates following these two methods. Materials and Methods: This study is a clinical trial and 168 term pregnant women were selected from elective cesarean candidates and divided in to general and spinal anesthesia groups by randomized allocation method. Then Apgar scores in first, fifth and twentieth minutes were mesured in infants. Also maternal age, cause of cesarean, sex and duration of cesarean section time were all documented. Data was analyzed using T and Chi square tests. Results: Mean Apgar scores were 8.66±0.68, 9.8±0.42 and 9.970.15 at first, fifth and twentieth minutes in general anesthesia group, and 90.38, 9.880.32 and 10 at first and fifth and twentieth minutes in spinal group. The group differed significantly for first minute Apgar score (p<0.001) but there were no significant differences in fifth and twentieth minutes Apgar scores. Conclusion: First minute Apgar score of newborns of mothers under spinal anesthesia was more than those of mothers under general anesthesia but there was no difference between their five minute Apgar score.
Seyede- Masoume Hosseini-Valami, Seyed-Abbas Hossenini-Jahromi, Farshid Rahimibashar,
Volume 15, Issue 2 (6-2012)
Abstract

Background: One of the most important complications of tonsillectomy is laryngospasm which leads to airway obstruction, arterial hypoxemia, and hypercarbia. Thus the present study was carried out to compare the effect of propofol with sodium thiopental, as an induction agent of anesthesia, on the incidence and intensity of laryngospasm after extubation in tonsillectomy. Materials and Methods: This double-blind clinical trial was done on 60 3-12-year-old patients who were chosen for elective tonsillectomy at Qods Hospital in Qazvin. The patients were randomly divided into two equal groups. Method of anesthesia was the same in these two groups except for the induction of anesthesia one group received sodium thiopental and the other group received propofol. At the end of the operation, patients were extubated after the restoration of spontaneous respiration with adequate tidal volume and respiratory rate. Then the incidence and intensity of laryngospasm was evaluated. Data were analyzed by t-test, Chi-square, and Fisher's exact test using SPSS software. Results: Overall, 83% of the patients in the sodium thiopental group and 93% of the patients in the propofol group did not develop laryngospasm and there were no statistical differences between the two groups in terms of the incidence and intensity of laryngospasm after extubation in tonsillectomy (P=0.535). Conclusion: As an induction agent in general anesthesia, propofol has the same effect as sodium thiopental on the incidence and intensity of laryngospasm after tonsillectomy.
Mohammadreza Ghodraty, Faranak Rokhtabnak, Alireza Kholdebarin, Alireza Pournajafian,
Volume 23, Issue 2 (5-2020)
Abstract

Background and Aim: Postoperative shivering is a common complication after recovering from anesthesia, and due to its subsequent side effects, its prevention and treatment is of special importance for anesthetists. In this study, the efficacy and onset of action of meperidine (which is a potential cause of hemodynamic and respiratory complications) in treatment of post-anesthesia shivering are compared with those of ondansetron.
Methods & Materials: In this clinical trial study, patients with post-anesthetic shivering during recovery were randomly divided into two groups of meperidine (n=27) and ondansetron (n=29). Their shivering scores were recorded every minute for up to 10 minutes. After this time, if patients did not improve, meperidine was used in both groups to treat shivering.
Ethical Considerations The study obtained its ethical approval from the Research Ethics Committee of Iran University of Medical Sciences and has been registered in Iranian Registry of Clinical Trials (IRCT201109224969N3).
Results: The number of patients completely treated at 10 minutes was higher in the meperidine group (P= 0.05), and the decrease in mean shivering score occurred faster in meperidine group (P= 0.047)
Conclusion: Although ondansetron has been shown to be effective in treatment of postoperative shivering, the effectiveness and onset of action of meperidine was clearly better.


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