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Introduction: Tribulus was traditionally used as a diuretic, mild laxative, urolithiasis, dysurca for treatment of urinary tract problems including stones, cystitis and infections, particularly Gonohrea. Antimicrobial cffects of methanol extract of Tribulus fruit on few gram positive and negative bacteria, the causative agents of some bacterial infections was evaluated and then compared with some in use antibiotics for these infections.
Materials and Methods: In this research as an experimental study. 40 gr powder of Tribulus fruit was dissolved in 100 ml pure methanol as a solvent with cold maseration method, the suspension was filtered after 5 day. The filtered suspension were concentrated with rotary evaporator apparatus in vaccum and was then dilluted with methanol to yield different concentrations. The antimicrobial activity of the extract and antibiotical were examined with disc diffusion and tube dilution standard methods to measure the diameter of inhibition zones, minimal inhibitory concentration and minimal bacterial concentration.
Results: The results were shown that the antimicrobial effect of the methanol extract of Tribulus fruit on ATCC strains of Streptococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas acroginosa had bactriostatic effect with the concentration of 400, 200, 100, 100 ug/ml in order. The comparison of urinary tract infections, including Oxacilin, Ciprofloxacin, Penicilin G, Gentamycin, Cotrimoxazole, Nalidixic acid and Nitroforantoin were shown that Tribulus fruit extract in concentration used in this research had a similar or even better effect than some antibiotics on some of the bacteria used in this evaluation.
Conclusion: The Tribulus fruit extract has an efficient bactriostatic and bactricidal activity of few gram positive and negative bacteria, the causative agents of some bacterial infections and these cffects are comparable to those antibiotics in usc for treatment of these infections. Tribulus fruit extract could be suggested for treatment of these infections after the pharmacological and clinical complementary studies.

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Introduction: Preeclampsia is one of the three major causes of death in pregnant women. Researcher believed that consuming proper nutrients can be a solution. In the last few years, the effect of type of fruits and vegetables on prevention of preeclampsia has been investigated, but there are still questions about the proper amount (unit) of fruits and vegetables. Materials and Methods: This case-control study was done on pregnant women referring to Thaleghani hospital in Arak. 35 pregnant women with preeclampsia were selected as case, and 70 healthy pregnant women as control group. The two groups were matched. Data were collected with a questionnaire consisting of two parts, first demographic information and second information about the amount of consumed fruits and vegetables. Each woman was questioned about food consumption 3 month before and during second trimester of her pregnancy. Portion of fruits and vegetables was calculated per week and then compared between the two groups. K-S, Leven, Mann-Whitney, and Chi2 tests were used for analyzing data. Results: In preeclampsia group, 3 month before pregnancy mean consumption of fruits and vegetables was 7.69±16 per week, and in healthy group was 12.43±1.87. There was a significant difference between the two groups (p=0/029). In the second trimester of pregnancy the mean was 11.03±1.6 and 13.95±0.98 in case and control group, respectively. Differences were significant (p=0.03). Incidence of preeclampsia was increased in group with less than 25% consumption of fruits and vegetables before pregnancy (less than 5unit per week) (P=0.05, OR:2.32, 95%CI:1/7, 7/24). This difference was also significant in the second trimester (P<0/03, OR:2.57, 95% CI:1/4, 54/29). Also in women who consume less than 8 units per week, the incidence of preeclampsia was increased. Conclusion: It was concluded that it seems there is relationship between consumption of fruits and vegetables with decreasing occurrence of preeclampsia. So researchers suggest that high risk groups of women be identified and educated to consume fruits and vegetables.