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Introduction: End stage renal disease (ESRD) is a major health problem and each year the number of patients is increasing. If the disease becomes irreversible, patients must always be hemodialyzed. Since mortality rate will increase due to inadequate dialysis, determining the efficacy of hemodialysis and improving its quality is very important. The main goal of this research is investigating the efficiency of hemodialysis. Materials and Methods: This is a cross-sectional analytical study which was conducted on 103 people who were under dialysis treatment in the Vali-e-Asr hospital of Arak in year 2003. Weight, blood pressure (before and after dialyze), time of dialysis, BUN and Cr before dialysis and 5 minutes after turning of the pump and before the second dialysis were measured. Data was analyzed by T test and Pearson correlation. Results: The mean of KT/V was 0.58 ± 0.1 normal protein catabolic rate (nPCR), 0.36 ± 0.11 g/kg per day and time average concentration of urea (TAC), 43.3 ± 14 mg/d which had a significant difference with standard measures (p<0.05). KT/V was 0.49 ± 0.18 and 0.47 ± 0.10 for men and women respectively which was significantly different (p<0.03). There was a positive and linear relationship between education level and TAC, KT/V and number of dialysis per week. Conclusion: Regarding the low efficiency of hemodialysis in 80% of patients and lower levels of hemodialysis efficacy indicators in comparison to standard measures, periodic assessment and also investigating the reasons of low efficacy of hemodialysis is recommended.

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Introduction: Left ventriculor hypertrephy (LVH) is one of the complicotions of systemic hypertension. LVH increases probabiltis of cardiac arrhytmia and cardiovasculer event in hypertensive patiants. In addition to hypertension other factors such as dyslipidemia, hyperglicemia and renal failure can cause LVH. This study was designed to investigate the effects of Body Mass Index (BMI) and some laboratory factors on LVH. Materials and Methods: This is a case-control study in which patients in case group (hypertensive patients with LVH) and patients in control group (hypertensive patients without LVH) were compared for BMI, dyslipidemia, hyperglycemia, and elevated Blood Urea Nitrogen (BUN) and Creatinin. Data was analyzed using Chi square test and logistic regression. Results: BMI with, high blood glucose with, high BUN and Creatinin signiticant affect in LVH presentation in hypertensive patiants. Dyslipidemia had not signiticant affect. Conclusion: In this study BMI, hyperglicemia, high BUN and Creatinin affected LVH presention in hypertensive patiant. So it is recommended that these factors be carfuly monitored and and treated.

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Background: Physalis Alkekengi is a perennial plant with a creeping and ryzumy stem belonging to the solanaceae family. This study investigates the possible effects of Physalis Alkekengi on plasma concentrations of some biochemical factors. Materials and Methods: Fifty male Wistar rats weighing an average of 190 ± 5 g were divided into five groups of ten: Control group without receiving any substances, control group with 2.0 ml/dl administration of the solvent, and three experimental groups receiving 0.4 (maximum), 0.2 (medium), and 0.1 (minimum) g/kg intra-peritoneal (IP) injections of the drug. The intra-peritoneal (IP) injection of the drug was done for 14 days and after this period, for conducting lab tests, blood sampling was done and the results were analyzed through ANOVA and Tukey test. Results: According to the results, protein and albumin plasma concentrations showed a significant increase (P<0.05) while creatinine plasma concentration, bilirubin, and urea nitrogen (BUN) did not reveal any significant changes. Conclusion: This family of plants contains significant amounts of glucocorticoids, such compounds are likely to increase liver and plasma proteins. In addition, due to the presence of compounds, such as physaline, vitamin C, and albumin, this extract is likely to increase blood pressure and, eventually, increase glomerulic refinement and diuretic properties therefore, the absence of significant increases in plasma concentrations of the substances produced by metabolism in plasma seems reasonable

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Background: Hemodialysis is the most common method of treatment in patients with end-stage renal diseases (ESRD). Given the importance and the role of permeability of hemodialysis membranes in removing the materials and particles, they were divided into two categories Low and High Flux.This study aimed to compare the effects of membranes in removing electrolytes and particles in ESRD patients.

Materials and Methods: In a crossover clinical trial, blood sampling from 30 patients undergoing hemodialysis was done in two sessions of hemodialysis using a Low Flux and High Flux membrane from arterial lines before and after hemodialysis in order to assess and compare the amounts of sodium, potassium, phosphorus, urea and creatinine was taken. Data were analyzed by SPSS 16 software.

Results: The mean age of samples was 47.46±10.74 years and 70% were men and 30% were women. Urea and phosphorus uptake was significantly higher in the high flux membrane (p=0.017)(p=0.006) respectively. Other parameters did not show significant differences between the two filters (p>0.05).

Conclusion: According to the results of research and high flux membrane features, we propose a high flux filter regularly be used in hemodialysis in the absence of specific ban.

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Abstract

Background: Ureaplasma and M. genitalium species belong to a kind of bacteria that are sexually transmitted and are the possible cause of pelvic inflammatory disease and nongonococcal urethritis, and et al. The aim of this study was to determine the urea plasma and Mycoplasma genitalium species frequency in women with vaginal infection and various sexual partners who referred to women^, s health promotion and treatment center in Arak.

Materials and Methods: Endocervical swab samples from 110 women with vaginal infections referred to women^’s health promotion and treatment center in Arak, were prepared. Patients’ personal information and identities during reception process were registered. The samples were transferred to the laboratory in the transport environment and after DNA extraction, were evaluated according to Real-time PCR assay.

Results: Urea plasma and Mycoplasma genitalium bacteria existed in 96(87.27%) and 4(3.63%) of patients, respectively. Among them, 4 cases had both bacteria infections. The amount of isolation in young women between 30-39 years old was more than others.

Conclusion: The results show that the colonization of urea plasma species in adult women is 40-80% and in studied group is 87.27%. These results indicate that with due attention to the increasing number of sexual partners and the increase of sexual activity, the urea plasma colonization of women will increase. In view of the potential influence of mycoplasma species on side effects resulted from pregnancy infection of mothers and mortality, on-time diagnosis and treatment will be increasingly essential.