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Introduction: Performing aerobic exercise programs during pregnancy will have positive effects on various characteristics related to the health of mother and children. Therefore, the aim of this study is to investigate the effect of aerobic activity of the mother during pregnancy on the levels of leptin hormone in the blood serum of adult rats.
Methods: This research is of an experimental type with a post-test design with a control group, including 20 female rats with an average age of 8 weeks, randomly divided into two training (T) (221 ± 8.9 grams) and control (C). (223±12.8 grams) groups. Pregnancy sports activity was performed immediately after the observation of vaginal plaque for 21 days and for 5 sessions per week with moderate intensity on the treadmill, and it was terminated 2 days before delivery. The comparison of leptin hormone level in two control and exercise groups was analyzed using independent t-test in 8-week-old mice at a significant level of P≥0.05.
Ethical considerations: This study was an experimental and interventional type, and the ethical standards in maintaining and conducting experiments are in accordance with the ethics code of this study (IR.QUMS.REC.1396.288) which has been approved by the Ethics Committee of the Faculty of Basic Sciences of Qazvin University of Medical Sciences.
Results: The amount of leptin hormone (p=0.002) in adult rats whose mothers had exercised during pregnancy was significantly lower than the control group, the weight of food consumed by the mother in the last weeks of pregnancy in the group training was less than the control group and the weight of the adult rats in the training group was less than the control group.
Conclusions: It seems that sports activity during pregnancy can have positive effects on weight control and prevention of obesity in adult children.