Dr Azam Abdullahpour, Dr Reyhane Zarbaf, Ms Masoumeh Ahmadi,
Volume 25, Issue 5 (12-2022)
Abstract
Introduction: Performing aerobic exercise programs during pregnancy will have positive effects on various characteristics related to the health of mother and children. Therefore, the aim of this study is to investigate the effect of aerobic activity of the mother during pregnancy on the levels of leptin hormone in the blood serum of adult rats.
Methods: This research is of an experimental type with a post-test design with a control group, including 20 female rats with an average age of 8 weeks, randomly divided into two training (T) (221 ± 8.9 grams) and control (C). (223±12.8 grams) groups. Pregnancy sports activity was performed immediately after the observation of vaginal plaque for 21 days and for 5 sessions per week with moderate intensity on the treadmill, and it was terminated 2 days before delivery. The comparison of leptin hormone level in two control and exercise groups was analyzed using independent t-test in 8-week-old mice at a significant level of P≥0.05.
Ethical considerations: This study was an experimental and interventional type, and the ethical standards in maintaining and conducting experiments are in accordance with the ethics code of this study (IR.QUMS.REC.1396.288) which has been approved by the Ethics Committee of the Faculty of Basic Sciences of Qazvin University of Medical Sciences.
Results: The amount of leptin hormone (p=0.002) in adult rats whose mothers had exercised during pregnancy was significantly lower than the control group, the weight of food consumed by the mother in the last weeks of pregnancy in the group training was less than the control group and the weight of the adult rats in the training group was less than the control group.
Conclusions: It seems that sports activity during pregnancy can have positive effects on weight control and prevention of obesity in adult children.
Seyed Sarmad Zahmatkeshan, Hamid Rajabi,
Volume 28, Issue 4 (10-2025)
Abstract
Introduction: The aim of this study was to investigate the relationship between serum adropin levels and markers of renal function in active and inactive young people.
Methods: The present research was conducted using a correlational method.Fifty young men and women with an average age of 28.22 ± 2.27 years, height 170 ± 8 cm, and body mass index 24.72 ± 4.88 kg/m² participated in the present study. Subjects were divided into active and inactive groups based on Beck's questionnaire, and 3 cc of blood was taken from their brachial vein to measure levels of adropin, urea, uric acid, creatinine, blood urea nitrogen (BUN), albumin, and total serum protein. The normality of the data was determined through the Kolmogorov-Smirnov test, and the independent t-test was used to compare the mean of the data, and the Pearson correlation coefficient was used to determine the correlation.
Results: Although a strong, positive (r = 0.78 +) and significant (p < 0.05) correlation was observed between adropin and physical activity, the renal function markers did not show a significant difference between the two active and inactive groups. No significant correlation was observed between renal function markers and adropin levels and between renal function markers and physical activity.
Conclusions: With increasing physical activity, the amount of adropin increases, but this increase does not change the levels of renal function markers in healthy people. Therefore, it seems that there is no relationship between adropin levels and renal function markers in healthy young people.
