Seyed Ziaeddin Rasi Hashemi, Ali Ramouz,
Volume 21, Issue 2 (5-2018)
Abstract
Abstract
Bakcground: Application of Talc powder, Bleomycin and Tetracycline is among conventional treatments in recurrent malignant pleural effusion caused by malignant pleurodesis. The aim of this research is to estimate the effect and safety in application of betadine as a cheap and available chemical factor in treatment of pleurodesis.
Materials and Methods: In this semi-empirical study, all patients suffering from recurrent pleural effusion enrolled the study. In order to perform pleurodesis, after chest tube insertion, solution containing iodopovidon, lidocaine, and normal saline was injected into the pleural cavity through chest tube. All the patients were examined for the pleural effusion and pleurodesis recurrence during a
6-month follow-up.
Results: In this study, a total number of patients was 50 among whom 23 were male (46%) and 27 were female (54%). In the 6-month follow-up, 40 patients (80%) were completely recovered and the recurrence of the pleural effusion was noticed in 10 patients (20%). Comparison of the success rate of recovery in terms of the gender of the patients showed no significant relation between gender and response to the recovery process (p=0.219). Of the total of 32 patients (64%) with chest pain after pleurodesis, 23 patients had complete recovery, and the incidence of chest pain in patients with no improvement was significantly higher (p=0.018).
Conclusion: Iodopovidone is a cheap, highly available material and of high efficacy in comparison to other sclerosant chemical substances, that provides an appropriate option in treatment of malignant pleural effusion.
Dr Abolhasan Halvani, Dr Sareh Rafatmagham, Dr Dorsa Saeedi,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: In this study, the effective factors in pleural malignancy based on pleural fluid characteristics and the type of primary tumor in Shahid Sadouqhi and Shahid Rahmonun hospitals of Yazd from 2019 to 2021 were evaluated.
Methods: In this descriptive study, 98 patients with pleural effusion referred for thoracoscopy to the thoracic surgery department in Shahid Sadouqhi and Shahid Rahmonun hospitals in Yazd were studied from 2019 to 2021. The method of data collection in this research was file reading. Among the patients who underwent thoracoscopy during this period, only patients who had at least one study of pleural fluid thoracentesis and pleural fluid analysis in terms of cytology (White blood cells (WBC) and Red blood cells (RBC)), protein, albumin, Lactate Dehydrogenase (LDH), and pH and after reviewing the biopsy pathology report the pleura of these patients were thoracocentesis. Those who had reported cases of pleural malignancy were included in the study. The database used in this research was a simple questionnaire containing the studied variables.
Results: In the examination of the pleural fluid of patients with pleural malignancy, in terms of the WBC level, most of the cases were below 1000 units per cubic milliliter. In terms of the LDH level, most of the cases were more than 1000 units/liter. More than 90% of cases had lymphocytes, and the lowest amount was 62 % of lymphocytes. All cases had exudative pleural fluid, which was exudative mainly due to LDH level and then due to both protein and LDH levels at the same time.
Conclusions: According to the findings, in patients with pleural malignancy, pleural effusion is exudative in all cases, mainly due to the effect of LDH in the pleural fluid. On the other hand, the percentage of white blood cells in all Cases of predominant lymphocyte percentage were seen.
