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Background: Measurement of mean arterial blood pressure is better predictive factor for pregnancy-induced hypertension than measurement of the systolic and diastolic blood pressure or systolic blood pressure. According to the theory of “protective effect of fish oil supplementation on pregnancy-induced hypertension “and the importance of blood pressure control in pregnancy, the present study was conducted to investigate the effect of fish oil supplementation in pregnancy on mean arterial blood pressure. Materials and Methods: In this clinical trial study, 120 healthy pregnant women were randomly divided into two groups of 60 persons. Same prenatal care was performed for both groups and the intervention group was received Salmon fish oil capsule 1000 mg/day, from 16th week to the end of the pregnancy. Systolic and diastolic blood pressure were measured in both groups once every four weeks up to 28th week, every 2 weeks from 28th till 36th week and once every week up to the end of pregnancy. Mean arterial blood pressure was calculated and all gathering data was analyzed with T test and Mann-Whitney test. Results: Mean arterial blood pressure in the intervention and control group was 80.76±5.50 and 78.46±4.50 mmHg which was not significantly different (p>0.05). Conclusion: The results showed that adding fish oil supplements to the diet of pregnant mothers had no significant effect on mean arterial blood pressure.

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Background: Acne vulgaris, is a chronic inflammatory disease of the pilosebaceous units. Genetic, environmental factors and nutrition influence on this disease. Recent studies indicate an essential role of nutrition in the development of acne, particularly with the effect on oxidative stress and inflammatory processes. Many studies have reported lower incidence of acne in individuals who receive diets containing large amounts of omega-3. The aim of this study was to determine the probable therapeutic effects of omega-3 for the treatment of acne.

Materials and Methods: In this study, 60 patients with moderate to severe facial acne were randomly divided into two treatment groups: 1) 100 mg doxycycline daily and one placebo capsule Omega -3 2) doxycycline 100 mg daily and one capsule 1000 mg Omega -3. Acne severity was determined based on GAGS system at the beginning of treatment and at the end of the sixth and twelfth weeks of treatment, with photographs obtained from each patient.

Results: There was a significant reduction in acne severity score (GAGS) at the end of sixth and twelfth weeks in the Omega-3 group in comparison to control group that received placebo.

Conclusion: Omega-3 fatty acids can improve moderate to severe inflammatory acne, probably due to their anti-inflammatory properties.