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Showing 2 results for Nephrotic Syndrome

Seyed Abolhassan Seyed Zadeh, Mohammad Reza Tohidi, Ahmad Reza Niki Bakhsh, Hashem Mahmood Zadeh, Hossein Emad Momtaz, Reza Dalirani, Farshid Kompany, Akram Soleymani,
Volume 16, Issue 2 (5-2013)
Abstract

Background: Idiopathic nephritic syndrome (INS) is one of the chronic illnesses in children. Therefore, clinical and laboratory factors that influence the clinical course of this disease are very important. Among these factors, low birthweight due to reduction of the number of congenital nephrons and subsequent glomerular hyperfiltration has been postulated as an important factor. This study was conducted to evaluate the clinical course of INS in patients with lowbirth weight in comparison to patients with normal birth weight.

Materials and Methods: In this descriptive-analytic study, 170 children with INS were selected from hospitals in Kermanshah, Urmia, Hamedan, Qazvin, and Ahvaz and divided into two groups of low birth weight (<2500gr) and normal birth weight (>2500gr). Then, the clinical course of these patients was evaluated by reviewing their medical records.

Results: Of the 170 patients, 22 had low birth weight and 148 had normal birthweight. Statistical analysis revealed no correlation between low birth weight and INS course except for age of presentation (P=0.014).

Conclusion: According to the results of this study, there is not any correlation between body birth weight and the clinical course of INS except for age of presentation.


Masoud Rezagholizamenjany, Parsa Yousefichaijan,
Volume 21, Issue 7 (2-2019)
Abstract

Nephrotic syndrome
Nephrotic syndrome is a manifestation of glomerular disease as a proteinuria in the nephrotic and triad of hypoalbuminemia, edema, hyperlipidemia, and high protein in the urine. Nephrotic proteinuria is defined as protein excretion of more than 40 mg/m2 of body surface per hour or protein to creatinine ratio of more than 2-3 at the first morning urine sample. Its annual incidence in most western countries is 2-3 cases per 100000 children per year, and in developing countries it is often higher due to malaria (1). New findings in this area are often about treatment, which are evaluated and reviewed in following.


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