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Showing 9 results for Myocardial Infarction

Babak Eshrati, Akbar Photohi, Seied Reza Madjd-Zadeh, Nazal Sarraf-Zadegan, Abbas Rahimi, Kazem Mohammad,
Volume 9, Issue 4 (12-2006)
Abstract

Introduction: Kalleh-Pacheh is an Iranian food used in many part of Iran and many other countries such as Afghanistan, Pakistan and India. We found no information regarding the effect of this food on acute myocardial infarction. The aim of this study was to assess the effect of this food, together with diabetes and smoking on myocardial infarction in Arak district. Materials and Methods: This was a case-cohort study which was performed in Arak district. In this study the data of Arak sub-cohort was taken from Isfahan healthy heart project which was performed in 2001. Cases were myocardial infracted hospitalized patients who were resident in Arak at the time of study. We showed the effect of different exposure, on myocardial infarction by estimating relative risk and population attributable fraction and 95% confidence interval. Results: In this study 150 cases were compared with 6339 sub-cohorts. The population attributable fraction for Kalleh-Pacheh was 19% (95% CI, 6 to 30%). This measure for diabetes and smoking was 31% (95% CI, 23 to 39%) and 41% (95% CI, 31 to 49%) respectively. Conclusion: According to the results of our study smoking, diabetes and using Kalleh-Pacheh has significant effect on myocardial infarction
Korush Rezaei, Hamid Reza Kohestany, Nayereh Baghcheghy, Mohammad Reza Yazdan Khah Fard,
Volume 11, Issue 4 (12-2008)
Abstract

Background: Delay in treatment of acute myocardial infarction has an important effect on developing the myocardial damage and the prognosis of the patients. In this study, interval between the onsets of symptoms until hospitalization was studied on patients who reffered to fatemeh Zahra hospital of Bushehr port. Methods and Materials: This is a cross-sectional analytic study, carried out on 120 patients, with acute heart attack in Bushehr hospital by using a sampling during 9 month period. A questionnaire was used consisted of three sections: first demographic information second, questions about time Interval between the Beginning symptoms to hospitalization and third questions about cause of delay that it was completed by inteviwe method. Results: Results showed that the total length of time between the onset of symptoms and hospitalization EU was 273/33±259 minutes. There was significant relation between positive family history, past history of CAD, having insurance, chief complain, going to physician clinic before hospitalization and age with the delay timed (P<0.05). The most common cause of delay was lack of knowledge about symptoms and inattention toward their importance. Conclusion: Time Interval between the onsets of symptoms to hospitalization approximately was 4.5 hours that was not acceptable. Findings indicate developing educational approaches to increasing patient’s knowledge is necessary for better understanding of symptoms in the onset of MI that hereby with the delay time reduces.
Valiollah Khadir Sharabiany, Saeed Oraii,
Volume 12, Issue 3 (10-2009)
Abstract

Abstract Background: Current electrocardiography (ECG) criteria are insensitive for the detection of posterior acute myocardial infarction (AMI) and most of these cases remain undiagnosed. The purpose of this study has been evaluated of prevalence and clinical value of ST-segment in posterior electrocardiography leads during acute myocardial infarction. Materials and Methods: In cross- sectional analytic study, posterior ECG leads (V7, V8 and V9) as well as standard 12 leads in 210 consecutive patients with acute myocardial infarction admitted to CCU wards of Shahid Rijaie hospital. Reinforcing, continuous arrhythmia, hypotension, cardiologic shock, marked heart failure and/or acute pulmonary edema were considered. Related parameters to basic characteristics and next process of patients in two groups with/ without ST- segment elevation in posterior ECG lead were compared. Results: There were 153 patients with ST-segment elevation 1 mm in 2 contiguous leads. 12.4% patients had STE1 mm in 2 posterior leads, either as an isolated finding (4.6%) or in association with STE at inferior or lateral sites (7.8%). The standard 12-lead electrocardiogram was normal in two patients and 5 other patients were admitted with the diagnosis of non-Q infarctions. Tall R waves in V1/V2 developed in 5 cases. In-hospital complications were significantly more frequent among patients with STE in posterior leads (47.4% vs. 20.9% respectively, P=0.01). Conclusion: STE in posterior electrocardiography leads is not uncommon during acute myocardial infarction and may portend a worse in-hospital course.
Reza Shahmirzaei, Saeed Sadrnia, Hassan Solhi, Ali Ghasemi,
Volume 13, Issue 2 (6-2010)
Abstract

Background: Positive electrocardiogram (ECG) changes in patients with unstable angina or non-ST elevation myocardial infarction are well known, but problem arises when no specific changes in ECG are identified. The aim of this study is to evaluate the prevalence of these changes in hospitalized patients at Amir Kabir Hospital of Arak. Materials and Methods: This study was a cross-sectional one that was conducted on 124 patients hospitalized at the heart emergency ward of Arak Amir Kabir Hospital with unstable angina and non-ST elevation myocardial infarction. ECG changes and serum cardiac enzyme levels were analyzed on admission and 12 hours after admission. Results: According to patients’ history and serum cardiac enzymes, 62 patients had undergone myocardial infarction without ST segment elevation, 98.4% of whom had ECG changes and 1.5% showed no ECG changes. Of the 60 patients, who had been hospitalized with unstable angina, 90% showed ECG changes and the rest 10% revealed no such changes. Conclusion: In comparison to other studies reporting that 50% of patients with unstable angina and non ST elevation myocardial infarction reveal no ECG changes, a high percentage of patients referring with a chest pain to the heart emergency ward of Amir Kabir Hospital, had no significant changes in their ECG and were not hospitalized.
Vida Shafipour, Leila Shafipour, Hedayat Jafari,
Volume 14, Issue 5 (11-2011)
Abstract

Background: Cardiac rehabilitation is one of the essential components of caring in cardiac patients both in hospital and community. Therefore, this study was carried out to determine the effects of cardiac rehabilitation program on the quality of life in patients with myocardial infarction. Materials and Methods:This clinical trial was conducted on two groups (experimental and control). Thirty patients with myocardial infarction at Heart Center Hospital of Sari were randomly assigned to each group. The experimental group participated in the Home-based Cardiac Rehabilitation Program (3 visits at home in weeks 4, 8, and 12) however, the control group did not receive any intervention. Data were collected via demographic data and SF-36 quality of life questionnaires and patients’ home-based health behaviors checklist. Data analysis was done by Chi Square, ANOVA and Mann-Whitney tests using SPSS software version 16. Results: The two groups were homogenous in terms of demographic characteristics. The patients’ quality of life increased in the experimental group in physical and mental dimensions and in total before and after the intervention (P<0.001). In addition, the comparison of the quality of life showed a significant difference between experimental and control groups (P<0.001). Conclusion: Cardiac Rehabilitation Program at home can improve the quality of life in these patients therefore, its implementation is recommended.
Hosein Shokri, Davood Hekmatpou, Hamid Reza Ebrahimi Fakhar, Akram Nyazi, Mohsen Azadi, Mohsen Taghizadeh,
Volume 16, Issue 7 (10-2013)
Abstract

Background: Patients with myocardial infarction are faced to multi stressors in which cause to increase their anxiety. This study with the goal of determination of the effect of Durosia Anethifolia (Barilax) on anxiety after myocardial infarction was accomplished.

Materials and Methods:This is a clinical trial which was done on 90 patients with MI. All people were selected by simple method at first and then they randomly allocated into two intervention and control groups. After 24 hours, perl of Barilax 1oo mg twice per day were prescribed for intervention group, and the same dosage of placebo were given to control group. Anxity rate 24 and 96 hours after MI by state Trait Anxiety Inventory (STAI) were measured. All data with X2 and paired T test were analysed.

Results: The mean age of patients in intervention group was 60.68 and 61.46 in control group. In intervention group 51% male and 49% were female and in control group 71% were male and 29% were female. Before intervention, the mean of anxiety rate in intervention group was 46.91 and in control group was 42.24 with no significant difference. After intervention, the mean of anxiety rate in intervention group was 33.35 and in control group was 36.48 with significant difference (p=0.012).

Conclusion: Oral consumption of Durosia Anethifolia (Barilax) on anxiety rate after myocardial infarction was effective. So description of this drug as an effective drug on controling of anxiety after myocardial infarction is recommended.


Behfar Pakbaz, Navidreza Mashayekhi, Alireza Ali Saeidi, Mohamadreza Taheri-Nejad, Reza Shah Mirzae,
Volume 17, Issue 5 (8-2014)
Abstract

Background: Early, complete, and stable coronary revascularization is the main criteria for standard treatment in patients with ST segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the safety and efficacy of integrilin as glycoprotein IIb/IIIa receptor inhibitor in treatment of STEMI patients undergoing primary percutaneous coronary intervention (PCI).

Materials and Methods: In this clinical trial study, 106 STEMI patients who complained of acute chest pain and were referred to Amir Al Momenin hospital, Arak, entered the study. Patients were randomly divided into two equal groups. The first group was treated with integrilin immediately before angioplasty. The 2nd group was treated with conventional percutaneous coronary intervention.

Results: After receiving treatment and undergoing angioplasty, TIMI Frame Count was equal to 15.7±8.04 in the 1st group and 14.2±5.4 in the 2nd group which showed no significant difference between them (p=0.4). Ejection fraction in patients receiving integrilin was significantly more than control group in first (p=0.043) and third month (p=0.012) after treatment.

Conclusion: Based on the results of the present study, it seems that using integrilin in standard time, causes long-term benefits for patients and reduces damage to the heart wall.


Mohammad Malekipoya, Bahram Abedi, Mohammad Reza Palizvan, Abbas Saremi,
Volume 22, Issue 3 (8-2019)
Abstract

Background and Aim: Extensive prevalence of myocardial infraction, and an increase of 36% in total deaths due to it by 2020, and attention to the causes and methods of alternative therapy is very important. There are different ways in treating these patients that endurance training is one of them. The aim of this study was to evaluate the effect of 8 weeks of incremental endurance training on serum levels of TSP-1 and MMP-1 in male Wistar rats with myocardial infarction.
Materials and Methods: In this controled experimental study with control group, 20 rats weighing 230 ±30 g (8-week-old) were randomly divided into incremental endurance training and control, after induction of infarction with Isoproteronol (150 mg/kg). The training group performed an 8-week training session (3 sessions a week, for 20 to 50 minutes at 12 to 18 meters per minute).Then, 24 hours later, the venous blood sample was collected to evaluate serum concentrations of TSP-1 and MMP-1 and transferred to the laboratory. Independent t-test was used to analyze the data at a significant level of p <0.05 to Graphed Pad software.
Ethical Considerations: This study with research ethics code IR.IAU.ARAK.REC.1397.007 was approved in Research Ethics Committee of Islamic Azad University, Arak branch, Iran.
Findings: The results showed that endurance training significantly increased serum MMP1 levels (p = 0.048) in rats with myocardial infraction, while there was no significant effect (p = 0.092) on the exercise program in serum TSP-1 levels.
Conclusion: the result of this study suggests that increasing endurance training may increase MMP-1 in rats with myocardial infraction, which can play an important role in angiogenesis and replacement of capillaries.

Mis Freshteh Shahidi, Mr Majid Kashef, Mis Zohreh Delfani,
Volume 24, Issue 6 (1-2022)
Abstract

Background and Aim : Despite progressive improvement in medical therapy and standard care, Exercisebased rehabilitation programs have been shown to to have beneficial cardiovascular effects in patients with myocardial infarction through a multifactorial effect. This review study aimed to evaluate exercise-based cardiac rehabilitation strategies in patients with myocardial infarction with special focus on high intensity interval training, as a growing field of research was conducted.
Material and Methods: This is a systematic review study on articles published, without limitation Year, by searching in reputable databases such as PabMed, Science Direct, Google Scholar, Scopus, Springer. Also in the process of searching for articles on the keywords microRNAs (miRNA) and myocardial infarction "," cardiac rehabilitation and myocardial infarction "," cardiac rehabilitation and high-intensity interval training  (HIIT) ", high-intensity interval training (HIIT) and Myocardial infarction was used.
Ethical considerations: All Ethical principles in writing this article have been observed  according to the instructions of the National Ethics Committee and the COPE regulations.
Results: High-intensity interval training (HIIT) is a safe and effective exercise strategy to improve cardiac function in MI, and to prevent abnormal changes in mass, size, geometry, and cardiac function after MI, and Applies significant changes in molecular targets and cell pathway.
Conclusion: Therefore, HIIT targets myocardial necroptosis due to oxidative stress, protects the heart against adverse left ventricular regeneration after MI, and can be considered an integral part of post-MI cardiac rehabilitation programs.


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