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Showing 2 results for Muscle Damage

Leila Vesaliakbarpour, Mohammad Ali Samavatisharif,
Volume 19, Issue 4 (7-2016)
Abstract

Background: Endurance training can lead to tissue damage and destruction by creating oxidative stress. But, it seems that exhaustive and endurance swimming indicated different results with each other. The purpose of this research was to compare two kinds of endurance swimming training on levels of LDH, CK and MDA in male Wistar rats.

Materials and Methods: 18 male Wistar rats with 12 weeks old, weighting 250 to 300 g, were randomly divided into three groups (6 in each): 1) endurance swimming (EN), 2) exhaustive swimming (EX) and 3) Control (C). Both groups swam for 1 h/d and 5 d/w for 10 weeks. Swimming duration in EX groups was increased progressively by fiveth weeks, by 30 min/week, reaching 3 h/d by final 3 weeks of traninig protocol. In this duration, C group didn't receive any intervention. One day after the end of training protocol, blood samples of rats were obtained on vena cava. The activity of lactate dehydrogenase (LDH) and creatine kinase (CK) was measured with DGKC method and malondialdehyde (MDA) through reaction with TBA. Results were analyzed using the one- way ANOVA followed by a Tukey test. Significant level was 0.05.

Results: EN groups significantly increased the levels of CK compared with EX and C groups (p=0.001), when indicated significantly lesser levels of MDA than C group (p=0.011). But, no significantly difference observed in the levels of LDH.

Conclusion: It seems that endurance swimming creates more muscle damage, while were generates lesser lipid peroxidation.


Foad Asjodi, Phd, Hamid Mohebi, Ebrahim Mirzajani, Azimeh Izadi,
Volume 20, Issue 4 (7-2017)
Abstract

Abstract

Background: The aim of this study was to evaluate the effects of supplementation of Branched-Chain Amino Acids (BCAAs) plus carbohydrate (CHO) and whey protein plus CHO on muscle damage indices after eccentric resistant exercise.

Materials and Methods: Twenty four untrained healthy males participated in this study. They were randomly divided into three groups, BCAA +glucose (0.1+0.1g/kg) supplement group (n=8), Whey+glucose (0.1+0.1g/kg) supplement group (n=8), and placebo (malto dextrin 0.2g/kg) group (n=8). Each subject consumed a carbohydrate beverage with addition of whey protein or branched-chain amino acid or placebo 30 minutes before exercise in a randomized,double-blind fashion. Serum levels of Creatine Kinase (CK), Lactate dehydrogenase (LDH), and muscle pain were measured before, 24, 48, 72 h after exercise. Follow-up analyses included 1-way repeated measures ANOVAs, and Bonferroni post hoc comparisons.

Results: 24 h after test, serum levels of CK, LDH and muscle pain in both supplement groups were increased less than placebo group (0.015, 0.001 and 0.001, respectively). Also, the levels of CK and LDH showed significant changes in both intervention groups compared to placebo group at 24 h (0.001, 0. 015, respectively). Similarly, significant differences in the levels of CK and LDH between groups were observed.

Conclusion: These data indicate that muscle damage and pain after resistant exercise were reduced by an ingestion of either BCAA drink or whey protein drink.



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