Shahla Enshaieh, Amir Hossein Siadat, Ali Asilian, Mohammad Ali Nilforoush-Zadeh , Fariba Iraji, Mohsen Khatami-Pour , Rezvan Fasih,
Volume 6, Issue 2 (7-2003)
Abstract
Introduction: Androgenetic alopecia is a very common disease. According to some reports, up to 96% of people have some form of this disease. In this paper we compared the effect of an herbal drug composed of the urticadioica, chamomilla, thymus vulgaris, equisetum arvense and foeniculum vulgare with 2% Minoxidil solution in the treatment of androgenetic alopecia.
Materials and Methods: We evaluated 82 patients suffering from androgenetic alopecia in a double blind prospective study. We counted terminal and vellous hair in 1 square centimeter of the predetermined area of scalp before and after treatment. After 6 months of treatment, the results were evaluated
Results: According to our findings, herbal drug and Minoxidil were effective in regrowthing the hair (45% vs. 35% respectively) and there were no meaningful differences between efficiacies of these two drugs
Conclusion: Herbal drug can be used as an adjunct or as an alternative to Minoxidil for treatment of the androgenetic alopecia.
Mina Mirnezami, Bahman Sadeghi, Sajid Ghadbighi, Farid Sahabi, Mojtaba Ahmadloo,
Volume 22, Issue 5 (11-2019)
Abstract
Background and Aim Male Androgenic Alopecia (MAA) is one of the most common causes of hair loss in men. Minoxidil solution is one of the most commonly used medications for MAA treatment; however, it has several cutaneous side effects including itching, scaling and erythema, which cause the discontinuation of its consumption.
Methods & Materials In this double-blind randomized clinical trial, 51 males with MAA were treated with 5% minoxidil solution and 7% chamomile extract. At the same time, 49 patients as controls were matched with this group and treated with 5% minoxidil solution alone. Both groups were treated and followed up for 6 months.
Ethical Considerations This study has received its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences (code: IR.ARAKMU.REC.1395.456) and is a registered clinical trial (Code: 2017042420258N41).
Results In both groups, the severity of itching and scaling gradually decreased. in the control group, erythema increased, while in the chamomile group, erythema also decreased. All three side effects of itching, scaling and erythema were lower in the group treated with chamomile extract and minoxidil solution than in the group used minoxidil solution alone.
Conclusion It seems that simultaneous administration of 7% chamomile extract and 5% minoxidil solution leads to a reduction in the severity and duration of cutaneous side effects caused by minoxidil solution use in treatment of MAA. It can increase the patient's compliance to the treatment and eventually the chance of MAA treatment.
