Showing 4 results for Kinetic
Soleiman Zand, Hadi Hasan-Khani, Parvin Soltani,
Volume 10, Issue 1 (3-2007)
Abstract
Introduction: End stage renal disease (ESRD) is a major health problem and each year the number of patients is increasing. If the disease becomes irreversible, patients must always be hemodialyzed. Since mortality rate will increase due to inadequate dialysis, determining the efficacy of hemodialysis and improving its quality is very important. The main goal of this research is investigating the efficiency of hemodialysis. Materials and Methods: This is a cross-sectional analytical study which was conducted on 103 people who were under dialysis treatment in the Vali-e-Asr hospital of Arak in year 2003. Weight, blood pressure (before and after dialyze), time of dialysis, BUN and Cr before dialysis and 5 minutes after turning of the pump and before the second dialysis were measured. Data was analyzed by T test and Pearson correlation. Results: The mean of KT/V was 0.58 ± 0.1 normal protein catabolic rate (nPCR), 0.36 ± 0.11 g/kg per day and time average concentration of urea (TAC), 43.3 ± 14 mg/d which had a significant difference with standard measures (p<0.05). KT/V was 0.49 ± 0.18 and 0.47 ± 0.10 for men and women respectively which was significantly different (p<0.03). There was a positive and linear relationship between education level and TAC, KT/V and number of dialysis per week. Conclusion: Regarding the low efficiency of hemodialysis in 80% of patients and lower levels of hemodialysis efficacy indicators in comparison to standard measures, periodic assessment and also investigating the reasons of low efficacy of hemodialysis is recommended.
Azam Gholamian, Adeleh Divsalar, Mahboubeh Eslami Moghadam, Maryam Saiedifar, Ali Akbar Sabory ,
Volume 17, Issue 2 (5-2014)
Abstract
Background: Catalase is a basic antioxidant enzyme that exits in human organs, mainly in the liver. The liver as a main tissue in the body that plays a substantial role in the catabolism and detoxification of drugs is a target of toxic and carcinogenic effects of many drugs. In the present study, the side effects of an anti-cancer compound of oxali-palladium on the function and structure of liver catalase were investigated.
Materials and Methods: In this experimental study, changes in the enzyme activity were studied by conversion in substrate (hydrogen peroxide) absorption at wavelength of 240 nm, using UV-visible spectroscopy in the absence and presence of different concentrations of oxali-palladium at room temperature. Furthermore, the effect of oxali-palladium on the tertiary structure of catalase was investigated using fluorescence spectroscopy via studying the changes in the intrinsic enzyme emission in the absence and presence of different concentrations of oxali-palladiumat at both room and physiologic temperatures.
Results: Kinetics data showed that the Km value of bovine liver catalase was 26.8 mM. Moreover, in the presence of different concentrations of oxali-palladium‚ the enzyme activity showed a gradual decrease in a dose-dependent manner (p<0.001). Fluorescence data presented changes in the tertiary structure of the enzyme by quenching fluorescence emission‚ that indicated alteration in protein chromophore environment.
Conclusion: It could be concluded that inhibition of catalase enzyme by anticancer drug of oxali-palladium increases the content of reactive oxygen species. Increase in reactive oxygen species values is one of the chief mechanisms of different anticancer drugs.
Mohsen Barghamadi, Sara Imani Broj, Hamed Sheikhalizadeh,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: Today, disabled sports have become one of the most important categories in the world of sports. In the meantime, exercising the blind and visually impaired is essential. Therefore, the present study aimed to examine the effect of clothing weight on the range of lower limb muscle activities during the execution of archery skills in blind people.
Methods: The current research is semi-experimental and laboratory-type. The statistical sample of the present study included 30 blind boys from Ardabil City who were selected purposefully and voluntarily. The subjects were randomly divided into two groups. The shooting target was placed at a distance of 10 meters from the subject. A two-way analysis of variance and a t-test at a significance level of 0.05 were used for statistical analysis of the data.
Results: According to the obtained results, the effect of the time factor on the electrical activity of the vastus medialis muscle when releasing the bowstring was statistically significant. The impact of the group factor on the electrical activity of the tibialis anterior muscle when releasing the bowstring had a statistically significant difference. Also, the effect of the group factor when taking the bow in the rectus femoris muscle and biceps muscle had a statistically significant difference.
Conclusions: Finally, according to all the obtained results, it can be said that probably using shooting clothes by affecting the electrical activity of the muscles of the lower limbs can improve balance during shooting, which can be one of the influential reasons, and become efficient in the success of archers.
Mohammadrahim Amiri, Bayan Heydaryan, Fariba Moradivastghani, Sara Imani Brouj,
Volume 27, Issue 2 (5-2024)
Abstract
Introduction: The present study findings aimed to investigate the effect of exercises based on the American National Academy of Sports Medicine principles (NASM) on walking kinetics in piriformis syndrome in middle-aged men.
Methods: The current research was semi-experimental and laboratory-type. The statistical sample of the present study was 30 men with piriformis syndrome. Subjects were equally and randomly placed in two intervention and control groups. The intervention group performed NASM exercises for eight weeks. Before and after the exercises, the ground reaction force variables were measured using a Bartek force plate device with a sampling rate of 1000 Hz. Kinetic data were smoothed using a fourth-order Butterworth filter with a frequency cutoff of 20 Hz. For statistical analysis, analysis of variance and paired T-test were utilized at the significance level of P < 0.05.
Results: The findings of the present study showed that the effect of time on the FxHC and FyHC components at the peak of the forces and the FyHC component at the time of reaching the peak of the ground reaction force increased in the post-test compared to the pre-test. P > 0.025;
d = 0.64 - 0.96. The effect of the time factor in the FyPO component at the peak of the ground reaction force in the post-test was less than the pre-test (P < 0.025; d = 1.64-0.96). The interaction effect of the time × group in the FxPO component at the peak of the force and the FzHC component at the time of reaching the peak of the ground reaction force had a significant difference (P < 0.048; d = 0.87-0.83).
Conclusions: The NASM exercises used in this research can have a clinical and therapeutic effect that can reduce damage to the lower limbs and improve the quality of walking in people with piriformis syndrome.
