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Showing 2 results for Interleukin-6
The effect of aerobic interval training on IL-6 and IL-10 serum concentration in women with type II diabetes
Rohullah Ranjbar, Abdolhamid Habibi, Farzaneh Abolfathi, Najeme Nagafian,
Volume 19, Issue 7 (10-2016)
Abstract

Background: Known inflammatory factors in type II diabetes and complications are delaying adjustment this factor, it is an effective approach in preventing complications.The aim of this study was to evaluate the effect of eight weeks aerobic interval training on interleukin-6 and interleukin-10 serum levels, in women with type II diabetes.

Materials and Methods: In this study, 18 patients with type II diabetes in Ahvaz city, were randomly divided into the two experimental group (n=10) and control group (n=8). The experimental group did the aerobic interval training and pedaling on the ergometer bicycle with 65 to 80 percent of their maximum leg power for three times a week during the eight weeks. The blood samples were prepared in two pre-test and post-test steps to measure the interleukin-6  and interleukin-10 serum levels through ELISA method.

Results: Statistical analysis showed that after eight weeks of aerobic interval training, interleukin-6 and interleukin-10 serum levels, related to the experimental group had no significant difference in comparison with control group (p>0.05).

Conclusion: The results indicate that doing the aerobic interval training for three times a week during eight weeks with 65 to 80 percent of maximum leg power, it has no effect on inflammatory and anti-inflammatory indices, in women with type II diabetes.


Dietary and protein intake reduce the risk of mortality in critically ill patients in the intensive care units.
Najmeh Hejazi, Farid Zand, Seyed Jalil Masoomi, Marzieh Akbarzadeh, Zahra Sohrabi, Zahra Moosavi Shirazifard,
Volume 28, Issue 6 (1-2026)
Abstract
Introduction: The aim of the present study was to investigate the relationship between the nutritional status of patients with different methods on the day of admission and dietary intake during the stay with the ICU mortality rate.
Methods: In this prospective cohort study, 125 patients were studied from admission to discharge in eight ICUs. At the time of admission, the nutritional status of the patients was assessed using the SGA questionnaire, anthropometric measurements, biochemical indices, body composition markers and the assessment of Organ Function Impairment (SOFA) and Severity of Illness (APPACHE) scores. The prescribed and received diet of the patients during their stay was recorded. By recording the mortality cases of this unit, the factors related to the mortality were also determined.
Results: Based on the SGA questionnaire, the rate of malnutrition on the day of admission was 28.8% and 29.6% of patients died during their stay in the intensive care unit. It was also found that a one-unit increase in serum IL-6 level and SOFA score at admission increased the risk of death during the stay in the ward by 1.008 and 1.14, respectively (P=0.003 and P=0.01), and with a one-gram increase in protein intake, the risk of death during the stay in the ward decreased by 8% (P<0.001).
Conclusions: This study showed that serum interleukin-6 level and SOFA score at the time of admission and the amount of protein intake during the stay in the ward affect the mortality rate in the ICU patients.
 
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