Niloofar Agharezaee, Flora Forouzesh,
Volume 23, Issue 5 (11-2020)
Abstract
Background and Aim: Coronaviruses are a large family of viruses that cause disease in humans and animals. Coronavirus Disease 2019 (COVID-19) is an acute respiratory infectious disease caused by a new coronavirus. The World Health Organization has declared this infectious disease as a global pandemic.
Objective: This study aims to review the latest research advances in genetics, pathogenicity, and clinical features of COVID-19, as well as current therapies to combat this disease.
Methods & Materials: This is a systematic review study on articles published from 2010 to 2020 by searching in reputable databases such as PubMed, Scopus, Google Scholar, Web of Science, and ScienceDirect.
Ethical Considerations: Ethical principles have been observed in accordance with the guidelines of the National Ethics Committee and the COPE regulations.
Results: Examining the genome and genetic studies of the virus, it can be said that there are many similarities between different coronavirus types, but there are differences in their genomic and phenotypic structures that can affect their pathogenesis. Re-use of existing therapeutic drugs, previously designed for other infections and viral pathologies is currently the only practical approach to fight COVID-19. The tests for SARS-CoV-2 genome-specific vaccines and the therapeutic antibodies are currently being tested, but they require a long-term process and complete safety testing.
Conclusion: Rapid diagnosis of SARS-CoV-2 infection is the basis of disease control. There is currently no specific antiviral drug approved for SARS-CoV-2 infection. Therefore, preventive measures are necessary to stop and control the spread of COVID-19, according to genetic studies and the obtaining knowledge of the molecular mechanism of this virus.
Jamal Rezaei Orimi, Bita Ghazizadeh, Azam Khosravi, Seyyed Amir Hosein Latifi, Mehdi Salehi, Mohammad Hosein Asadi, Seyed Abdollah Mahmoodi,
Volume 28, Issue 4 (10-2025)
Abstract
Introduction: Studies examining scientific output provide valuable insights into the development and growth of research activities. The primary objective of this article is to evaluate graduate theses in the field of the history of medicine in Iran from 2001 to 2021, with a particular focus on research trends, the contributions of universities and academic institutions, and patterns of scholarly activity.
Methods: This research is of an applied type and was conducted using the quantitative content analysis method. The statistical population of the research consisted of 558 theses published in universities and scientific centers of the country. Data were collected using a structured content analysis checklist and subsequently analyzed employing descriptive statistical methods.
Results: The research findings indicate that Tehran University produced the highest number of theses with 66, followed by Shahid Beheshti University of Medical Sciences with 49, and Payame Noor University with 36. The highest number of theses were written in 2017 (9.67%), and the lowest number was in 2003. Moreover, the history, professional doctorate, and Persian language and literature departments published the highest number of theses, with 160, 78, and 46, respectively.
Conclusions: The results of this research show that the history of medicine in Iran has experienced significant growth in the past two decades. This growth is evident in the increasing number of theses and the increased participation of universities and scientific centers.
