Showing 10 results for Hearing Loss
Arash Bayat, Mohammad Farhadi, Hesamodin Emam Jomeh ,
Volume 6, Issue 1 (3-2003)
Abstract
Introduction: The existence of acoustic trauma secondary to drill noise during chronic ear surgeries has not yet been clearly demonestrated. This investigation aims to document the hearing loss that occures in patients who underwent mastoidectomy.
Materials and Methods: Sixty-three (38 male and 25 female) consecutive patients (11-57 years) who underwent modified radical mastoidectomy were included. In a concurrent clinical trial design, we measured bone conduction thresholds before and after (1 week and 1 month) operation on both sides.
Bone conduction thresholds were assessed in 250, 500, 1000, 2000, 3000 and 4000 Hz frequencies.
Results: Paired-test results showed a satistically significant temporary (TTS) and permanent threshold shifts (PTS) were occured in the 2000-4000 Hz region for operated (on addition to 1000 Hz) and non-operated ears, but clinically PTSs were not remarkable and TTSs were important only for operated ear (P<0.05). The correlation between duration of noise exposure and magnitude of threshold shift was only significant in operated ear in 2000-4000 Hz region (P<0.05).
Conclusion: We could not demonestrate any permanent hearing loss caused by drill-generated noise, but resultant noise is able to produce TTS in the operated ear in 2000-4000 Hz region. We found poor relationship between duration of noise exposure and magnitude of threshold shifts.
Arash Bayat , Mohammad Maleki, Mehdi Akbari, Reza Salehi,
Volume 7, Issue 1 (3-2004)
Abstract
Introduction: The phone's sound beams are known to be a valid test that reflects the activity of foreign hair cells, and are therefore very useful for assessing cochlear changes, such as those that occur after exposure to noise.
method: In one clinical trial, 74 volunteers aged 18-25 were examined by simple random sampling. The results of audiometric tests of the participants' pure sounds and tympanometry were within the norm on the day of the experiment. In this study, the phonetic tests of the phone were spontaneous, transient, and distorted from both ears of the subject, which was considered as a basic level of evaluation for us. Then a person's ear was selected and in the intensity of SPL 100 decibels and for 5 minutes in his ear was given a turn. After 2 minutes after the end of the presentation, the previous evaluations were repeated in both ears and the range of responses in both ears was compared.
Results: In 34 participants, submucosal nostrils led to a decrease in amplitude or SOAE responses. One of the interesting findings in this study was the emergence of new peaks in SOAE responses in the opposite ear after the presentation of the sound. The proposed noise created a significant statistical decrease in the range of TEOAE response both in the affected ear and in the opposite ear. Comparing the mean amplitude of DPOAE responses before and after exposure to shift-induced noise in the ear was significant in the Hertz range of 1699-6299, but this comparison was not significant in the opposite ear. The mean time of DPOAE incubation before and after exposure to shingles did not show a statistically significant difference in both the affected ear and the opposite ear.
Conclusion: The findings show that the phone's sound beams are a good tool for tracking hearing damage caused by noise. TEOAEs are also more sensitive to tracking than other tests, and can even be used as a very fast screening tool to assess susceptibility to hearing damage caused by noise before entering high-end industrial environments. And considered sound.
Ali Khavanin, Mohsen Soleimani, Mehdi Akbari, Ramazan Mirzaie, Masoud Motallebi, Hasan Asiliyan, Ardalan Soleimanian,
Volume 14, Issue 2 (5-2011)
Abstract
Background: Trauma noise is one of the major physical pollutants in modern societies. Sound conditioning, on the other hand, is known as one of the mechanisms for protecting the hearing system.
Materials and Methods: In this experimental study, 15 three month-old male white New Zealand rabbits were divided into three groups. The equipments used in this study included a sound generator, a loudspeaker, an exposure box, a sound level meter, and a distortion product otoacoustic emission (DPOAE) device. The rabbits were assigned to trauma noise exposure, conditioning noise exposure, and control groups. The conditioning and traumatic sound levels were respectively 80 and 105dB within the 500-3000 Hz frequency.
Results: Conditioning noise at the level of 80 in combination with trauma noise enhanced the rabbits hearing system tolerance up to 13-17 dB so that in all frequencies there were significant differences between the trauma noise exposure group and the sound conditioning and trauma noise conditioning group (P<0.05).
Conclusion: Sound conditioning can act as an effective factor in protecting the hearing system against trauma noise.
Abolfazl Jafari, Reza Badiei, Maryam Yarmohammad Tooski, Behieh Kohansal,
Volume 14, Issue 5 (11-2011)
Abstract
Background: Noise-induced hearing loss is a noticeable clinical issue. The aim of this study was to evaluate the effect of N-Acetylcysteine on the reduction of permanent noise-induced hearing loss in workers at Hepco Company.
Materials and Methods: In this clinical trial, in a one-month period from October to November, 118 male 22-52 year-old workers with at least 5 years of experience working in places with permanent high tone noise (more than 850db) were selected and divided to experimental and control groups. The experimental group received Fluimucil (NAC) and the control group received vitamin B1. Hearing ability of the two groups was evaluated through audiometry after the one-month period.
Results: In the control group, hearing loss was significant and it was in direct relationship with age and job experiment. The placebo (vitamin B1) did not have any significant effects on preventing hearing loss. In the experimental group, there was significant hearing loss in higher frequencies and at 6000, a relative improvement was observed, whereas with increases in age and job experience hearing loss became more significant which was rather low in comparison with the control group.
Conclusion: The findings of this study shows that using N-Acetylcysteine has significant effects on NIHL (high tone loss) in higher frequencies. This study can be used as the basis for launching future studies on reducing the damages induced by noise
Maryam Delphi, Mahsa Bakhit, Mojtaba Tavakoli, Ali Nikkhah, Azadeh Saki,
Volume 16, Issue 1 (4-2013)
Abstract
Background: ASSR is the latest threshold detection technology in pediatric audiology. The aim of this study is to investigate the degree to which ASSR thresholds correlate with click-ABR thresholds.
Materials and Methods: In this cross-sectional study, 32 children ranging in age from birth to 7 years were evaluated by ASSR and ABR in moderate to severe and severe to profound hearing loss groups.
Results: The correlation coefficients for frequencies of 500, 1000, 2000, and 4000, mean of 2-4 and mean of 1-4 kHz were between 0.68- 0.90 in moderate to severe hearing loss and 0.79-0.96 in severe to profound hearing loss.
Conclusion: Strong correlations were found between ASSR and click-ABR thresholds in all frequencies. This correlation was greater for higher degrees of hearing loss.
Parisa Tahmasebi, Seyed Reza Kazemi Nezhad , Mohammad Amin Tabatabaiefar, Javad Mohammadi Asl, Nader Saki,
Volume 19, Issue 6 (9-2016)
Abstract
Background: Hearing loss is a common sensory impairment in humans which half of its causes are genetic reasons. Genetic hearing loss can be divided into the two types of syndromic and non-syndromic, which 80% of non-syndromic cases is Autosomal Recessive Non-Syndromic Hearing Loss. The aim of the present research is to determine the contribution of DFNB2 locus (MYO7A gene) in causing an autosomal recessive hearing loss in the one group of the deaf families of Khuzestan province.
Materials and Methods: This study was conducted on 26 families with autosomal recessive hearing loss (with 4 patients) and negative for GJB2 mutations in Khuzestan province. 22 families suffered from ARNSHL and 4 families suffered from Usher syndrome. Linkage analysis was performed by using STR (Short Tandem Repeat) markers related to DFNB2 locus. Each family’s genotype was determined by PCR-PAGE method. Furthermore, haplotypes drawing and LOD score calculations were performed.
Results: From 26 families with hearing loss participating in this research, following genetic linkage analysis and haplotypes drawing, two families (7.7% of the families) showed linkage to DFNB2 locus. One family (4.5%) suffered from ARNSHL and another family suffered from Usher syndrome.
Conclusion: The results of the present research show that the contribution of DFNB2 locus in causing hearing loss in the population of Khuzestan province was similar to other studies conducted in Iran and this locus with other important loci should be considered to check in the hearing loss panel.
Mahtab Khosrofar, Mohammad Reza Pourreza, Samira Asgharzadeh, Parisa Tahmasebi, Elahe Ali Asgari, Reza Ghasemikhah, Nader Saki, Javad Mohammadi-Asl, Morteza Hashemzadeh Chaleshtori, Mohammad Amin Tabatabaiefar,
Volume 20, Issue 3 (6-2017)
Abstract
Abstract
Background: Hearing loss (HL) is the most common congenital defect in humans. One or two in thousand newborn babies have prelingual hearing loss. Autosomal recessive non-syndromic hearing loss (ARNSHL) is the most common form of hereditary deafness. Hearing loss is more common in the developing countries which is due to genetic and environmental (cultural -health factors) reasons. HL has a wide range of clinical demonstrations including: congenital or late onset, conductive or sensory-neural, syndromic or non-syndromic hearing loss. The goal of this project is to determine the portion of the DFNB21 (TECTA) in ARNSHL in families with negative GJB2 gene in Khuzestan province.
Materials and Methods: We studied 21 families with ARNSHL with at least 4 patients and negative for GJB2 mutations from Khuzestan province. Genetic linkage analysis was performed using STR markers linked to DFNB21 locus.
Results: Following genetic linkage analysis and haplotyping, out of 21 families with ARNSHL, one family showed linkage to the DFNB21 (TECTA) locus.
Conclusion: The results of this project confirm other studies in Iran and give insight into the most common loci causing ARNSHL in Iran which could be helpful in research and clinic.
Sedigheh Safaeian Titkanlou, Toktam Maleki Shahmahmood, Zahra Ghayoumi-Anaraki, Fatemeh Haresabadi, Majid Haddadi Avval, Mohaddeseh Soltani, Mohsen Rajati Haghi,
Volume 23, Issue 6 (11-2020)
Abstract
Background and Aim: Phonological awareness skills, as part of phonological processing abilities, can predict the extent of success in acquiring written and reading skills. Phonological awareness skills are of concern in children with severe and profound hearing loss, which has been less studied in this population. Thus, this study aimed to evaluate these skills in Cochlear-Implanted (CI) children and compare them with their healthy counterparts.
Methods & Materials: The study population included 25 CI children and 25 healthy children, aged 4-6 years, who were monolingual Persian speakers. The selected CI and healthy children were selected from the Rehabilitation Center of Naqmeh and the Kindergartens in Mashhad, City, Iran, respectively. After selecting each participant, the test of phonological awareness was administered. To compare the mean scores of each subtest, the obtained data were analyzed in SPSS v. 21 using the Mann-Whitney U test.
Ethical Considerations: This study was approved by the Research Ethics Committee of Mashhad University of Medical Sciences (Code: IR.MUMS.REC.1396.263).
Results: The mean scores of CI children were significantly lower than that of their healthy peers in all phonological awareness subscales (P<0.05).
Conclusion: The obtained data suggested that healthy children presented better performance than the CI children in the phonological awareness test. Poor phonological awareness skills in CI children seem to be associated with hearing deprivation before cochlear implantation; thus, it requires to speed up surgery at an early age and the implementation of an effective rehabilitation program.
Pedram Pouryari Biyachal, Najmeh Ranji, Ali Nazemi,
Volume 24, Issue 1 (3-2021)
Abstract
Background and Aim: Non-syndromic hearing loss is a genetically heterogeneous disorder. Mutation in the GJB2 gene is a major cause of non-syndromic hearing loss in numerous countries. This study aimed to evaluate GJB2 mutations in 31 individuals with non-syndromic hearing loss
Methods & Materials: In this descriptive cross-sectional study, the required blood samples were collected from 31 individuals with non-syndromic hearing loss in Rasht and Bandar Anzali Cities, Gilan Province, Iran. After DNA isolation, the GJB2 gene was amplified by the PCR method and underwent sequencing.
Ethical Considerations:This study was approved by the Ethics Committee of the Islamic Azad University, Mashhad Branch (Code: IR.IAU.MSHD.REC.1398.027).
Results: In this study, 3 mutations were determined in 18 individuals with hearing loss. Accordingly, 35delG mutation had the highest frequency (48.38%) in individuals with hearing loss as homozygote (n=14) and heterozygote (n=2). A patient with heterozygosity in V153I mutation and a patient with compound heterozygosity in 35delG/G200R mutation was determined.
Conclusion: It appears that 35delG mutation is a common mutation in the GJB2 gene in individuals with non-syndromic hearing loss in Guilan Province.
Sousan Salehi, Maryam Tarameshkou, Saeed Mirahmadi, Saghar Hashemnia, Milad Hassansheikhi,
Volume 25, Issue 3 (8-2022)
Abstract
Background and aim: It is suggested that hearing impaired children with hearing aids and cochlear implant, showed poor pragmatic abilities. Pragmatic is the most related language component to social interaction. Further, it has effect on personality development and self-esteem. The main aim of the present study is investigating the relationship between pragmatic abilities and self-esteem in hearing impaired children.
Materials and methods: Sixty hearing impaired children with hearing aids or cochlear implant were included into this study according to inclusion and exclusion criteria. Then parents or other caregivers were asked to fulfill Children’s Communication Checklist (CCC) and self-esteem questionnaire. The participants were divided into three groups based on hearing impairment severity, including: severe, moderate and mild. The relationship between pragmatic ability and self-esteem was examined in three groups and without considering categorization, by Pearson correlation coefficient, significant level was 0.05.
Ethical considerations: This project is approved in Arak university of medical sciences with ethical registration code IR.ARAKMU.REC.1399.150. All parents gave written informed consent form.
Findings: the results illustrated that there is significant relationship between pragmatic abilities and self-esteem in all hearing impairment children without considering categorization (p<0.05). By considering categorization, significant relationship was showed in self-esteem and pragmatic abilities in moderate and mild groups (p<0.05).
Conclusion: according to our analysis, pragmatic abilities and self-esteem are related. This relationship is more obvious in low severity impairment.
