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Background: In the recent years, oxidative stress was attended as one of the causal factors of ischemic stroke. In terms of the role of genetic, geographic and ethnic factors in the prevalence of stroke, This study was designed to compare the oxidative stress indexes of stroke patients with normal healthy subjects in this geographic area. Methods and Materials: In this case-control study, 36 patients older than 50 years with ischemic stroke and 45 healthy subjects with same age and sex, were enrolled. Five milliliter blood were drawn from all subjects. Samples were centrifuged and plasma was separated. Total antioxidant capacity, lipid peroxidation and thiol levels were measured respettively by FRAP, TBA and HU methods. Then the result was analyzed using t-test. Results: Results showed total antioxidant capacity and thiol plasma levels were lower in stroke patients in compare to healthy subjects, but only the thiol group had significant difference(P=0/001). Although lipid peroxidation showed a slight but non-significant difference in stroke patients in compare to control group. Conclusion: These findings suggest oxidative stress in patients with acute ischemic stroke may be conseaqence of an imbalance in oxidant/antioxidant homeostasis. Therefore it may be useful to recommend antioxidant medications or diet for these patients.

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  Background: Imbalance between the production of free radicals and the antioxidant defense system causes oxidative stress. The cardamom is the fruit of the Elettaria cardamomum maton which probably has an antioxidant property. Aim of this study is assess of effect of cardamom- tea watery extract on oxidative stress.

  Methods and Materials : This clinical trial research was carried out on 54 persons. Firstly 5ml venous blood was collected and the parameter of the oxidative stress in their blood was evaluated. Then they were given every day 3 grams of cardamom and 1 gram of tea as like as 100 ml cardamom- tea watery extract for two weeks. After 2 weeks 5 ml blood was collected and the parameters of oxidative stress in their blood serum was evaluted for the second time. The parameters of first and second group of bloods were compared by SPSS software.

  Results : The mean of total antioxidant capacity of serum before and after cardamom- tea extract were 1.96 ± 0.64 m mol/ml and 2.23 ± 0.46 m mol/ml respectively (p=0.009). The mean of lipid peroxidation before and after cardamom- tea were 14.97 ± 3.58 nmol/ml and 12.07 ± 5.91 nmol/ml respectively (p=0/002). The mean of total thiol group before and after cardamom- tea were 0.224 ± 0.200, 0.266 ± 0.166nmol respectively (p=0.141).

  Conclusion: The cardamom- tea reduces the amount of lipid peroxidation and enhanced the antioxidant markedly. So, the cardamom- tea decreases the amount of oxidative stress in blood. Ther- fore the cardamom- tea in the people diet is usful.

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Introduction: Paints are composed of extensive variety of hazardous substances, such as organic solvents and heavy metals. Occupational exposure to paint increases oxidative stress, hematological disorders, and DNA injury. This study was performed to explore the beneficial effects of Selvit on the paint workers by measuring total antioxidant capacity, lipid peroxidation, and blood parameters as main oxidative stress biomarkers.

Materials and Methods: This clinical trial study was conducted on 25 male workers who worked in the paint factory. Serum markers such as total antioxidant capacity (TAC), lipid peroxidation (LPO) and also hematological parameters were measured before and after using Selvit (14 days). SPSS software was used for data analyses and paired t-test and Pearson correlation analysis were applied.

Results: Results showed that after using the Selvit, an increase in TAC and a decrease in LPO were observed but they were not significant. Also, aspartate transaninase significantly decreased after using Selvit and high density lipoprotein significantly increased.

Conclusion: Selvit have beneficial effect on hematological parameters due to its antioxidant capacity.