Showing 6 results for Contraction
Khadigeh Ahrari, Shabnali Alizadeh, Mohammad Rafie, Mohammad Reza Pallizvan, Ali Cyrus,
Volume 13, Issue 1 (4-2010)
Abstract
Background: Studies in different species indicate that a variety of different inhibitors may influence myometrium during pregnancy and withdrawal of one or more of them leads to the onset of labor pain. Hence, this study was done to investigate the association between parathyroid hormone-related peptide1-34 (PTH-rp1-34) and labor pain. Materials and Methods: This study was a case-control one. Plasma PTH-rp1-34, PTH, total calcium, phosphorous, magnesium, and alkaline phosphatase concentrations were quantified for 152 normal pregnant women at term (76 women at the onset of labor pain, as the case group and 76 women without labor pain, as the control group). The subjects had no pregnancy related complications. Results: The mean of plasma PTHrp concentrations in the group with labor pain (12.36±0.60 ng/ml) did not differ from that in the group without labor pain (13.57±0.63 ng/ml). The means of plasma PTHrp concentration amounts in the group with labor pain and the group without labor pain were 28.92±1.66 pg/ml and 31.88±1.64 pg/ml, respectively and there was no significant difference between the two groups. There were no significant difference in plasma calcium, phosphorus, magnesium, and alkaline phosphatase concentrations in the two groups too. Conclusion: In this study, the endocrinal role of PTHrp and the onset of labor pain was not confirmed.
Simin Taavoni, Somayeh Abdolahian, Hamid Haghani,
Volume 13, Issue 1 (4-2010)
Abstract
Background: Labor pain, which is a natural, unique and multi- factorial pain, is considereds a major part of women's anxiety at reproductive ages. There are two pharmacological and non-pharmacological approaches for reducing this pain. Since the pharmacological approach involves side effects, lots of attention has recently been given to the non-pharmacological methods. One of these methods, is use inc birth ball the, which includes sitting and rocking on the birth ball. The purpose of this study was to evaluate the effects of using birth ball on labor pain, the duration of active phase and contractions of physiologic labor. Materials and Methods: In this randomized control-clinical trial, sixty primiparous women (18-35 year old) were selected and randomly assighed into birth ball and control groups. The severity of pain was measured through Visual Analogue Scale (VAS) and the pain score, interval between contractions and duration of active phase were compared between the two groups. Results: The average pain score in the birth ball group was significantly lower than the control group (p<0.05). In terms of interval between the contractions, duration of active phase and uterine contractions, there were no significant differences between the two groups. Conclusion: Although use of birth ball did not have any effects on the duration of active phase, uterine contractions and interval between uterine contractions, this complementary therapy reduced the severity of pain during the active phase of delivery. Therefore, this safe method is suggested to be used during normal vaginal delivery and physiologic labor. Also, conducting a study, which examines the effects of using a combination of complementary methods, is recommended
Azam Govahi, Ahmad Ali Moazedi, Seyyed Mansor Seyyednejad, Mehdi Pourmahdi,
Volume 18, Issue 6 (9-2015)
Abstract
Background: Due to the harmful side effects of chemical drugs, in recent decades, much attention has been returned to the use of medicinal plants. The flavonoids as plant secondary compounds are allocated to own an important part of this attention. Based on previous studies, some of the flavonoids are able to reduce contraction induced by KCl, acetylcholine, etc in rat ileum. Therefore, in this study, the effect of the flavonoid extract of parsley leaves on smooth muscle contraction of the ileum and the role of Nitric oxide (NO) has been studied.
Materials and Methods: Distal segment of Wistar rat ileum was separated and contractions under one gram tension and at 37°C, in an organ bath containing Tyrode solution was recorded by isotonic method. Rats were divided into 2 groups with 7 in each group. After placing the tissue exposed to L-NAME 100&muM (Sigma, America) as an inhibitor of NO, the antispasmodic effect of cumulative concentrations of the flavonoid extract was investigated
Results: The extract cumulative concentrations reduced ileum contraction induced by KCl in a dose-dependent manner. Also, the antispasmoide effect of flavonoids extract on ileum contractions (only 16 mg/ml) was affected by L-NAME.
Conclusion: This study showed that the extract relaxed rat's ileum by the NO system at higher concentrations.
Raede Tavalaee, Ahmad Ali Moazedi, Mohammadkazem Gharib Naseri, Mohammadreza Akhond,
Volume 19, Issue 5 (8-2016)
Abstract
Background: because of the side effects of chemical drugs, using plant drugs was considered during recent decades. Based on previous studies, various concentrations of plant extracts can reduce ileum contraction caused by KCl and carbachol. Therefore, in this study, the role of muscarinic receptors in anti-spasmolytic activity of hydroalcohlic extract of parsley(petroselinum crispum)seed in adult male rat's ileum was investigated.
Materials and Methods: The distal part of Wistar rat’s ileum was separated and its contractions were recorded under 1 gr stretching and 37oC temperature in the bathroom containing the solution of Tyrode by Isotonic method. The ileum tissue was inserted in separately in first group affected by KCl and parsley seed, in the second group affected by KCl and carbachol with concentration 10-2 mg/ml and after that parsley seed, the third group affected by carbachol with concentration 10-2 mg/ml and then the extraction of parsley seed and the fourth group affected by scopolamine with concentration 10-3 M and after that KCl and then the extraction of parsley seed.
Results: Non-cumulative concentrations of extract reduced the ileum contraction caused by KCl (60mM) in a concentration-dependent form (p<0.001). There was a significant difference between the effect of extract in the presence of carbachol and extract concentration 0.2 mg/ml (p<0.01). There was no significant difference between the effect of extract in the presence of carbachol without stimulating tissue by KCl (60mM) with extract concentration 0.2mg/ml (p<0.05). There was no significant difference between the effect of extract in the presence of scopolamine with extract concentration 0.2mg/ml(p<0.05).
Conclusion: This study showed that the hydroalcholic of parsley seed extract has a relaxatory effect on rat’s ileum. Carbachol with KCl has a synergistic effect on smooth muscle contraction of the ileum wall and muscarinic receptors do not involve in the inhibitory function of parsley seed extract.
Abolfazl Kalantari, Hamid Rajabi, Pezhman Motamedi, Leila Poursaadat, Abbas Saremi,
Volume 25, Issue 6 (3-2023)
Abstract
Introduction: Increasing skeletal muscle contraction ability via increasing its neural stimulations, is one of the methods can be effective in sport performance improvement. The aim of the present study was to evaluate the effect of supramaximal isometric conditioning contractions on muscle neural excitation and performance indices during bench press exercise.
Methods: Current research is a semi experimental study performed on 8 athlete men. Age range of them was 19 – 23. Doing resistance trainings was a part of their exercise program at least 2 months before study onset. Bench press with Barbell was used in the protocol of these study. Electromyography was used in order to assay the neural excitation of main muscles which are activated during bench press. In addition, 1-RM test was done so as to assess the performance of these muscles. The protocol of this study was approved by the ethics committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1400.357). All subjects participated in this study voluntarily and they had no illness or injury at the start of the research.
Results: Neural excitation and performance of the muscles increased significantly during strength bench press, following conditioning contractions. This research was reviewed in Islamic Azad University - Arak Unit and approved with the ethics code IR.IAU.ARAK.REC.1401.096. Informed consent was obtained from the participants and they were assured that their information would be confidential
Conclusions: Doing supramaximal isometric conditioning contractions prior to doing strength bench press with barbell, increased neural excitation and performance indices of main muscles activated in this exercise.
Professor Hamid Rajabi, - Marjan Sheidaee, - Neda Khaledi,
Volume 26, Issue 6 (2-2024)
Abstract
Introduction: Athletes use diverse strategies, including caffeine supplementation, to reduce fatigue and improve their performance. The aim of the present study was to evaluate the effect of the post-activation potentiation method and caffeine supplementation on peripheral fatigue after Wikstrom's fatigue protocol in young male volleyball players.
Methods: In this study, forty male volleyball players with an average age of 27.33 ± 1.78 years and an average weight of 76.5 ± 7.45 kg participated. They were divided into four experimental groups: a group that used only the PAP method (n=10), a group that consumed only caffeine (n=10), a group that both performed PAP and consumed caffeine (n=10), and a control group (n=10). For the groups receiving caffeine, a caffeine supplement was administered at a dose of 6 mg per kilogram of body weight, 15 minutes before starting the protocol. PAP exercises were performed at an intensity of 70% of the one-repetition maximum. Blood samples were taken one hour before and one hour after completing the Wikstrom six-station protocol. All subjects participated in this study voluntarily and they had no illness or injury at the start of the research.
Results: The results of the present study showed that the implementation of PAP along with caffeine showed a significant increase in the variables of time to exhaustion and the number of rounds (p<0.05), while the rate of ammonia showed a significant decrease (p<0.05). In contrast, uric acid showed no significant difference (p>0.05).
Conclusions: The results of the present study, showed that the use of caffeine reduces peripheral fatigue. Also, since the use of PAP did not have an adverse effect on the participant's performance, athletes can use this method concurrently with caffeine to improve their performance in endurance activities.
