Journal of Arak University of Medical Sciences

Search published articles

Showing 2 results for Cardiac Troponin T

Cardiac Troponin and Creatine Kinase Response to the Three Modes of Training (Running, Pedaling and Swimming) in Young Girls

Abbas Saremi, Samaneh Ahmadi,
Volume 19, Issue 1 (4-2016)

Abstract

Background: Cardiac troponin T and creatine kinase are used as biological markers for cardiomyocytes and its levels in serum are used as indicators of myocardial cell injury. The purpose of this study was to compare the effects of 3 different training protocols (runing, swimming, and pedaling training) on myocardial cell injury biomarkers in young girls.

Materials and Methods: In this semi-experimental study with pretest–posttest design, ten healthy young girls (aged 23.0±1.6 y) were selected in a convenience sampling way. The subjects performed three types of exercise in 7 days interval. Blood sample was assessed before and after the exercise sessions. Data were analyzed using t-test and analysis of variance.

Results: Our results indicated that creatin kinase increased significantly after three types of exercise (p<0.05). Running exercise led to greater increase in serum creatine kinase (p<0.05). Also, troponin T levels significantly were increased after three types of exercise (p<0.05), although no significant differences were observed between exercise types (p>0.05).

Conclusion: Our data suggest that intensive exercise is associated with cardiac damage in less trained girls and the type of exercise is determinants of the magnitude of myocardial injury biomarkers release.

The Effect of Saffron Stigmas Aqueous Extracts on Serum Cardiac Troponin T and Creatine Kinase MB Isoenzyme of Male Rats Following an Exhaustive Exercise

Amir Khosravi, Fatemeh Omid Ali,
Volume 21, Issue 2 (5-2018)

Abstract

Abstract
Background: The exhaustive and strenuous exercise may cause damaging effects to the heart. The present study aims to investigate the effect of Saffron stigmas aqueous extracts on serum cardiac troponin T and Creatine kinase MB isoenzyme of male rats following an exhaustive exercise.
Materials and Methods: 64 Wistar male rats were assigned into following four groups (n=16) :1) without exercise +distilled water 2 ml, 2) without exercise+ aqueous saffron extract, 50 mg/kg+ distilled water 2 ml, 3) distilled water 2 ml + 8 weeks exercise, and 4) aqueous saffron extract, 50 mg/kg +distilled water 2 ml + 8 weeks exercise.At the end of experiment, half of the rats were killed immediately before exhaustive exercise; on the other hand remaining rats were killed immediately after performing an acute bout of exhaustive exercise on the treadmill. Serum cardiac troponin T and CK-MB isoenzyme levels were measured by ELISA and spectrophotometric methods, respectively. Data were analyzed by one–way ANOVA.
Results: The results show that in all groups, cardiac troponin T and CK-MB isoenzyme serum levels were significantly increased following an exhaustive exercise. The lowest increase was observed in group 4 and the highest increase was observed in group 1 (p<0.05).
Conclusion: Based on the results of this study, it can be concluded that the use of saffron extract with aerobic training is more effective than aerobic exercise or saffron extract alone in modifying the increase of serum troponin T and CK-MB isoenzyme level following an exhausting exercise.

Page 1 from 1

Designed & Developed by : Yektaweb