Showing 4 results for Candidia
Mehri Jamilian, Esmat Mashadi, Fatemeh Sarmadi, Maryam Banijamali, Elham Farhadi, Elham Ghanatpishe,
Volume 10, Issue 2 (6-2007)
Abstract
Introduction: Candidiasis is the second common cause of vulvovaginitis. We evaluate the frequency of species of Candida in vaginal candidiasis. Materials and Methods: In this cross-sectional anaiythical study, 220 patients with typic and nontypic signs and symptoms of vaginal Candidiasis were studied. Smear and culture were done. For positive culture, evaluation of germ tube, clamidospor production and carbohydrate assimilation and fermentation was done. Data was presented by descriptive statistics and analyzed using Chi square, Man-Whitney and Kolmogrov tests. Results: 40% of patients showed positive culture and smear. Frequancy of Candida Albicanse (42.03%), Dublininsis (29.5%), Glaberata (14.75%), Gilermondy (6.81%), Norvejensis (2.27%), Tropicalis (2.27%), and Kefayer (2.27%) were determined. There was no significant relationship between antibiotic and OCP consumption and type of identified Candida. Conclusion: Frequency of non Albicanse species is increasing. We suggest treatment based on culture and smear, because non Albicanse vaginitis usually is resistant to Azols.
Mahdi Taheri Sarvtin, Amir Farhang Zand Parsa, Parivash Kordbacheh, Jamal Hashemi, Mahmood Mahmoudi, Roshanak Daie, Mahin Safara, Ayat Ahmadi, Mahdi Osooli,
Volume 13, Issue 1 (4-2010)
Abstract
Background: Candida species are the most common yeasts that reside in oral cavity in 30 - 50% of people, and are capable to produce opportunistic infections within the oral cavity. This study was done to determine the effect of cigarette smoking on the type and degree of Candida oral carriage.
Materials and Methods: In this case-control study, oral Candida flora in 34 smoker and 66 non-smoker men were compared. All of the samples were collected by swab and examined by direct microscopy and culture on CHOROM agar Candida and corn meal agar media. Isolated colonies were identified by carbohydrate assimilation method using RapID Yeast PLUS System.
Results: Out of the 34 smoker individuals, 27(79.4%) had Candida colonization in their oral cavity while 30(45.5%) of the 66 non-smoker individuals had developed this kind of colonization. A significant difference was observed between the two groups (p<0.05). Additionally, there was a significant difference in the degree of colonisation and the type of candida species which were isolated from the oral cavity of the smoker and nonsmoker groups.
Conclusion: Cigarette smoking can act as an important underlying factor in oral candidiasis.
Soheila Nouraei, Sedigheh Amir Ali Akbari, Masomeh Jorjani, Hamid Alavi Majd, Ayyob Ghaforian,
Volume 16, Issue 4 (7-2013)
Abstract
Background: Genital tract infections are one of the main causes of frequent referrals to gynecological clinics. Vulvovaginal candidiasis is the second common infectious vaginitis. On the other hand, probiotics are microorganisms that can have beneficial effects on the host. Noticing the limited number of studies reporting new treatments for this disease, the present study was designed to compare the effects of the combination of fluconazole and oral protexin and fluconazole on the treatment of vulvovaginal candidiasis.
Materials and Methods: A double-blind clinical trial was conducted on 90 women who were referred to the 12-e-Bahman Clinic in 2011. The patients were randomly classified into "combination of fluconazole and oral protexin" or "fluconazole and placebo" groups. Data were analyzed by descriptive statistics and inferential statistics (t-test, Chi-square test, Fisher’s exact test, and McNemar’s test).
Results: The combinations, fluconazole-oral protexin and fluconazole-placebo, were equally effective in reduction of complaints and symptoms however, the effect of fluconazole-oral protexin on dysuria was more (p=0.02). Also, the fluconazole-oral protexin combination elicited a better therapeutic response (p=0.01). In addition, fluconazole-oral protexin combination treatment demonstrated a better recovery time (p=0.04).
Conclusion: This study demonstrated that complementary treatment with probiotic lactobacillus increased the efficacy of fluconazole in treatment of vulvovaginal candidiasis. Further research, however, is suggested.
Hosein Sohrabi, Mohammad Reza Sarookhani, Akram Ezani,
Volume 16, Issue 8 (11-2013)
Abstract
Background: Vulvovaginal candidiasis is a common problem in women. The purpose of this study was to compare two identification methods new PCR analysis (with DNA extracted from samples) and conventional culture technique in detection of Candida species in vulvovaginal samples.
Materials and Methods: In this experimental-analytical study, 150 women of fertility ages participated and two vaginal discharge samples were collected by speculum. One sample used for direct DNA extraction as well as PCR and the other was used for culture and phenotypic evaluations. Phenotypic evaluations waere performed by germ tube and chlamydospore formation and specially culture in chrome agar medium to detect color of the colonies. PCR was performed by DNA extracted from samples as templates and finally size of Candida specific amplicons was determined.
Results: From 150 samples, 87 in culture and 127 in new PCR technique were positive. In culture method, from total 87 Candida species , 73 C. albicans, 12 C. glabrata and 2 C. tropicalis were isolated whereas in new PCR technique, from total 127 candida species 107 C. albicans, 18 C. glabrata and 2 C. tropicalis were identified. Concordance of the two methods were calculated as 68 percent.
Conclusion: The new molecular method (innovative PCR) has the potential to rapidly and accurately diagnose Candida vulvovaginitis in patients and can be used for diagnosis of Candida species in clinical specimens.
