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Showing 4 results for C-Reactive Protein

Navid Mazruei Arani, Homa Baghaei, Ashraf Khorrami Rad, Zatollah Asemi, Sabiheosadat Alizadeh, Ahmad Esmaeilzadeh,
Volume 16, Issue 6 (9-2013)
Abstract

Background: Increased insulin resistance, inflammatory factors and parameters of oxidative stress are associated with the development of diabetes complications. This study was designed to determine the beneficial effects of synbiotic Gaz on insulin resistance, inflammatory factor and oxidative stress in patients with type 2 diabetes.

Materials and Methods: This randomized crossover double-blinded controlled clinical trial was performed among 62 diabetic patients aged 35-70 y. Subjects were randomly assigned to consume of either the synbiotic (n=62) or control Gaz (n=62) for 6 weeks. A 3-week washout period considered. The synbiotic Gaz was consisted of a probiotic viable and heat-resistance strain Lactobacillus sporogenes (1×107 CFU), 0.04 g inulin and 0.05 g stevia per 1 g as sweeteners' substances. Control Gaz (the same substance without probiotic bacteria and prebiotic inulin) was. Patients were received synbiotic and control foods in a 7 g package thrice a day. Fasting blood samples were taken at baseline and after 6-week intervention to measure insulin resistance, hs-CRP and biomarkers of oxidative stress.

Results: Consumption of synbiotic Gaz, compared with control, resulted in a significant decrease in serum insulin (p=0.02) and hs-CRP levels (p=0.008). Supplementation with synbiotic Gaz led also to a significant increase in plasma total glutathione (p<0.0001) compared to the control.

Conclusion: In conclusion, consumption of synbiotic Gaz for 6 weeks resulted in decreased levels of serum insulin, hs-CRP and increased levels of plasma total glutathione.


Masoumeh Habibian, Parvin Farzanegi, Seyed Mohsen Sadat Tabar Bisheh ,
Volume 18, Issue 9 (12-2015)
Abstract

Background: Inflammation plays an important role in the pathogenesis of atherosclerosis and change in lifestyle represents a successful strategy to prevent cardiovascular disease. Therefore, the present study investigated the combined effects of regulae Pilates training and Apium Graveolens seed supplement on monocyte chemoattractant protein-1(MCP-1) and C-reactive protein (CRP) in sedentary women.

Materials and Methods: In this quasi-experimental study, 28 healthy sedentary woman with age average 31±5.5 years old are selected in a convenience sampling way and randomely divided into and control, exercise, supplement and exercise+supplement groups. Pilates exercise was consisted of exercise movements at 50% to 80% maximal heart rate in, 3 sessions per week for 8 weeks. Supplement and exercise+supplement groups consumed 1.3 gr Apium Graveolens seed capsule three times a day after meals. Fasting blood samples were collected before and 48 hours after the last interventions. MCP-1 and CRP levels were measured by ELISA method.

Results: Eight weeks of Pilates exercise, supplementation and the combined intervention were associated with a significant increase in MCP-1 and CRP levels (p<0.05). Furthermore Pilates exercise and combined intervention were associated with significantly greater increases in percent changes of the MCP-1 and CRP compared to supplement group (p<0.05).

Conclusion: These findings suggest that the protective effect of Pilates exercise and Apium Graveolens seed supplementation non-drug interventions might in part be due to suppression of the inflammatory processes.


Amir Hosein Pazoki, Siroos Choobineh, Ali Akbarnejad,
Volume 19, Issue 1 (4-2016)
Abstract

Background: The evidence suggests that obesity causes the chronic inflammation. Chemerin is a new adipokine which is associated with obesity and metabolic syndrome. The effects of combined training on levels of inflammatory markers specialy chemerin and serum amyloid-A has been less studied.The present study aims to examine the effect of six weeks combined training on plasma levels of chemerin, CRP and SAA and plasma lipid in obese men.

Materials and Methods: 18 obese men were divided into control and experimental groups. General characteristics of subjects serum levels of chemerin, CRP and SAA were examined (by ELISA method), before and after one session training. Endurance training protocol was performed on the large muscles included in 6 weeks running around the track with 60 to 75% HRmax, 4 sessions per week, intense resistance training for 25 to 30 minutes with 50 to 70% of one repetition maximum of 6 stations (2 sets, 12 Reps). Data analysis was performed by T-independent test for comparison of two control and training groups, T-paired test for comparison of two groups before and after the test and significant level of p≤0.05 was considered.

Results: The results show that 6 weeks combined training significantly decrease the plasma levels of chemerin (p=0.004), and SAA (p=0.009), but there was not any significant decrease on CRP levels(p=0. 476). So, it can be concluded that combined training will affect on some inflammatory markers in obese men and improve them.

Conclusion: One session combined training for 6 weeks significantly affects on plasma levels of chemerin and serum amyloid-A, however, it doesn't decrease the plasma levels of C-reactive protein (CRP).


Shahnaz Shahrjerdi,
Volume 23, Issue 3 (8-2020)
Abstract

Background and Aim: Hypertension is a common disease and universal that can cause cardiovascular disease and kidney damage. The purpose of this study was to determine the effect of an eight-weeks massage on blood pressure (systolic and diastolic), heart rate and C-reactive protein in women with hypertension. 
Methods & Materials: In this quasi-experimental study, 44 volunteer women with Mean±SD age of 42.12±5.31years were selected from women referred to Arak Oil Company specialized polyclinic with hypertension. Four women excluded from the study for some reason, and the rest were divided into experimental and control groups. In massage group massage was done for three sessions per week, 45-60 minutes in each session, on the back and upper limbs for eight weeks. Data analysis was conducted using dependent and independent t-test by SPSS V. 25 statistical software at the significant level of (P≤0.05).
Ethical Considerations: This study (Code: 92-160-26) was approved in Research Ethics Committee of Arak University of Medical Sciences.
Results: The results showed that eight weeks of massage reduced blood pressure (P=0.001), the heart rate (P=0.001), and C-reactive protein (P=0.001) in women with hypertension compared to the control group (P=0.62).
Conclusion: The findings of this study showed that massage for eight weeks is an efficient and appropriate method to improve systolic and diastolic blood pressure, heart rate, and C-reactive protein in patients with hypertension.


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