Behrouz Moghaddasi, Zahra Moghadasi, Parvaneh Taheri Nasab,
Volume 13, Issue 2 (6-2010)
Abstract
Introduction: Researches indicates that physical training are a basic component of pulmonary rehabilitation in asthmatic patients , and can result in improvement of sign and symptoms of asthmatic patients.The purpose of present study is evaluation of the effects of physical exercises on pulmonary function and clinical manifestations and signs and symptoms of asthmatic patients.
Materials and methods: The samples included 24 asthmatic patients that participated in a physical exercise program have refered to Ardebil Bou _Ali Hospital (1386) .The researcher followed test –re-test design in the present study.
The data were collected using an asthma clinical manifestations questionnaire and pulmonary function test (Spirometery).
Results: Physical exercises program was effective in improvement pulmonary function of asthmatic patients, and exercises decrease asthmatic signs such as: attacks of wheezing, shortness of breath, chest tightness and coughing.
Conclusion: The results indicate that asthmatic patients would benefit from a physical training and such a physical exercise program can be adapted for use in clinical practice.
Farzad Nazem, Mojtaba Izadi, Majid Jaliliu, Behzad Keshvarz,
Volume 15, Issue 9 (2-2013)
Abstract
Background: Epidemiological studies have shown the relationship between incidence of asthma symptoms and environmental factors, such as sedentary lifestyle and metabolic and cardiovascular diseases. However, the role of exercise rehabilitation protocols on lung function in obese adult patients with chronic asthma is a controversial issue. The aim of the present study is to evaluate the impact of aerobic exercise on lung function in obese middle-aged men with chronic asthma. Materials and Methods: This semi-experimental study was conducted on 39 obese middle-aged males with mild and moderate asthma. The experimental group (n=19) with regard to the safe range 15≥ RPE>9 followed the sub-maximal rehabilitation exercise program (50 to 80% HRmax intensity) for 3 months. Then, they underwent one month of detraining. The control group (n=20) did not have any form of aerobic exercise. Spirometric parameters in base, three months of training, and one month of detraining were measured by standard methods. Results: Indicators of lung function, including FVC, FEV1/FVC, PEF, FEF%75, and MVV significantly decreased. The pattern of changes in FEV1, FEV1/FVC, and MVV remained stable even after a month of detraining (p<0.05). However, no significant changes occurred in the dependent variables of the control group (p>0.05). Conclusion: It seems that the incidence of physiological adaptations of aerobic exercise, as a non-pharmacologic clinical factor, after the one-month detraining period affected the spirometric parameters in obese asthmatic patients
Azam Zarneshan, Mohammadreza Zolfaghari, Mahdia Gholamnejad, Mehdi Yousefi,
Volume 20, Issue 8 (11-2017)
Abstract
Abstract
Background: IL-4 plays a key role in the pathogenesis of asthma and the increased serum level of that is positively correlated with asthma severity and obesity. IL-4 induces IgE secretion by B cells. Previous studies suggesting an anti-inflammatory effect of exercise training on asthmatic lungs. The aim of the present study was to investigate the effect of 12 weeks of aerobic exercise training on serum levels of IL-4 and IgE in overweight and obese asthmatic women.
Materials and Methods: 21 overweight and obese asthmatic women were selected and divided into two groups including experimental (n=12) and control (n=9) groups. The experimental group performed aerobic exercise training, three times a week, 60 minutes each session. Fasting blood samples were collected before and 2 days after completion of the course. The data were analyzed by using SPSS22 software
Results: A significant decrease in serum IL-4 (p = 0.015, t = - 2.68), BMI (p = 0.014, t = - 2.72) and weight (p = 0.001, t = -3.99) was shown following the 12 weeks of training in the experimental group compared to the control group. There were no significant correlations between the obesity changes and the Inflammatory Marker Changes (p>0.05).
Conclusion: The present study indicates that aerobic exercise training reduced the serum levels of IL-4 independent of obesity changes in overweight and obese asthmatic women.
