Background: Nowadays, with the development of drug resistance, the use of herbs as an alternative to chemical drugs is considered by researchers. In this work, effects of Aloe vera extracts on clinical isolates was studied.

Materials and Methods: Aloe vera plant medicinal plants were obtained from a greenhouse. Three extracts including essential oils, extracts and no essential oils and essential oil extraction method also includes a complete extract of Aloe vera were prepared Percolation total. To investigate Microbiology extracts of two strains of Staphylococcus aureus and Staphylococcus epidermidis clinical strain of Gram-positive and Gram-negative isolates of Klebsiella pneumoniae and Escherichia coli strains Staphylococcus aureus ATCC25923 were used as well. Evaluate the effect of two methods: Kirby-Bauer disk with the minimum inhibitory concentration (MIC) was performed using microplate dilution. Turbidity was determined by an ELISA reader apparatus.

Results: All extracts of aloe vera on Klebsiella with a diameter of 32±2 mm mg/ml 285.7 concentration with microplate dilution method was 2.23 mg/ml. Staphylococcus aureus and MIC zone diameter of 30±2 mm and mg/ml 2.23, Staphylococcus epidermidis and Escherichia coli mg/ml4.46 mm 17.85 mm 30±5 mg/ml 17.85 respectively. Similar concentration of 17.85 mg ml Aloe Vera with a circle formed by the disk mc/ml 10 gentamicin was shown. This effect is similar to other bacteria antibiotics gentamicin, clindamycin, erythromycin, and Cefixime compared with Aloe Vera extract has been proven. Essential oils made from all parts of the same whole extract of aloe vera, but not essential extracts, bacteria studied were ineffective.

Conclusion: In this study the effects of similarity and some excess water Asrsarh Aloe Vera with common antibiotics on bacteria causing the infection was confirmed. Therefore, by production of appropriate pharmaceutical plant drugs with fewer side effects, bacterial infections couled be treated properly.

Abstract

Background: The adipocytokine visfatin is secreted by the adipose tissue and is associated with plasma glucose level and can affect diabetes. Furthermore, aloe vera is used in traditional medicine as an anti-diabetic drug. The current study aimed to determine the effects of swimming along with taking aloe vera extract on visfatin serum level, glucose level, and the ratio of triglycerides to high-density lipoproteins in diabetic male rats.

Materials and Methods: In this experimental study, 28 diabetic male rats were chosen and placed in four groups of 1) control, 2) swimming, 3) aloe vera extract and 4) swimming along with aloe vera. The swimming program began with 6 minutes in the first week and increased to 36 minutes in the sixth week. Groups 3 and 4 received 300 mg/kg of aloe vera extract per day. Control group didn’t performe any regular exercise and also didn’t receive any extract. Data were analyzed by using ANOVA and the Tukey post hoc test.

Results: In all the three groups (swimming group, extract group and swimming along with extract group), there was a significant reduction in blood glucose, ratio of triglycerides to high density lipoproteins and the visfatin level compared to the control group (p≤0.05).

Conclusion: Results indicated that swimming together with aloe vera extract reduce the ratio of triglycerides to high density lipoproteins and glucose and increase visfatin receptors' sensitivity, and thus reduce visfatin serum levels in diabetic male rats.