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Showing 2 results for Adhesion

Hamid Motamedi, Shahnaz Dehbashi, Hamed Tahmasebi, Mohammad Reza Arabestani,
Volume 21, Issue 5 (10-2018)
Abstract

Background and Aim: Staphylococcus aureus(S.aureus) has many pathogens. Antibiotic resistance may increase the invasion of this bacterium. The aim of this study was to determine the role and effect of some antibiotic resistance in the spread of pathogenic strains of S.aureus in different clinical specimens.
Materials and Methods: 95 clinical isolates of S.aureus were collected from different clinical specimens. Antibiotic resistance pattern was determined by Disc diffusion method (Kirby-Bauer) for 6 different classes. Identification of adhesion agent genes in isolated isolates was performed using Multiplex-PCR and specific primers. For analysis of the results, GraphPad Prism version 6 and ꭕ2 statistical sampling was used. p≤0.05 was considered significant.
Findings: Of 95 isolates of S.aureus, 29 isolates (30.52%) were resistant to methicillin, 12 isolates (12.63%), resistant to clindamycin, 48 isolates (50.52%), resistant to gatyfloxacin, 88 (92.63%) isolates resistant to gentamicin, 57 (60%) isolates resistant to erythromycin and 79 isolates (83.15%) were resistant to tetracycline. fnbA genes were isolated in 14 isolates (14.73%), fnbB in 29 isolates (30.52%), fib in 21 isolates (22.10%), clfA in 17 isolates (17.89%) and clfB in 19 isolates (20%). There was a significant correlation between resistance to macular antibiotics, tetracycline, beta-lactam, lacosamide, aminoglycoside and pathogens.
Conclusion: The adhesion factors in S.aureus possibly cause some structural changes and cause resistance to various antibiotic classes.

Doctor Vahideh Nazari, Octor Mojtaba Didehdar, Octor Fateme Golestanipour,
Volume 24, Issue 6 (1-2022)
Abstract

Background and Aim: A common infection in complete or partial denture wearers is denture stomatitis. One of the most important factors in the adhesion of Candida albicans is the surface and chemical properties of the denture base materials. The aim of this study was to investigate the surface roughness and adhesion of Candida albicans to two different types of acrylic materials.
Materials and Methods: In this experimental study, 16 samples were prepared from each of Vertex and Ivoclar acrylic resin. The surface roughness of the samples was measured by a profilometer. The samples were then placed in a cell suspension of Candida albicans. After incubation and staining with acridine orange, the yeast cells attached to the acrylic samples were counted using a fluorescent microscope. Data were statistically analyzed by T-test.
Ethical considerations: This article is approved by the ethics committee of Arak University of Medical Sciences with the ethics code: IR.ARAKMU.REC.1398.301.
Findings: There was no statistically significant difference in the mean of surface roughness between the two study groups (P = 0.311). However, Candida albicans colonization in ivoclar acrylic was significantly lower than vertex acrylic. (P = 0.000).
Conclusion: Differences in surface topography and physical and chemical properties of Vertex and Ivoclar acrylic resin affect the adhesion of Candida albicans.

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