Showing 30 results for Icu
Valiollah Khadir Sharabiany, Saeed Oraii,
Volume 16, Issue 3 (6-2013)
Abstract
Background: Nowadays, many patients with cardiovascular diseases require pacemaker implantation that is associated with few complications such as cardiac and valvular insufficiency. This study aims to compare the development of tricuspid and mitral regurgitation in right ventricular outflow tract (RVOT) and right ventricular apex (RVA) pacing.
Materials and Methods: In this single-blind clinical trial, 164 candidates for permanent pacemaker (PPM) implantation due to sick sinus syndrome or atrioventricular block were randomly divided into 2 equal groups to receive either RVOT or RVA pacing. Patients with heart failure or valvular diseases were excluded from the study. Pre and post-procedural echocardiography after 6 months were performed and the results were compared for the development of mitral and tricuspid regurgitation and probable changes in the ejection fraction (EF).
Results: Age, gender, pacing mode, and baseline cardiac rhythm did not significantly differ between RVOT and RVA pacing groups. The incidence of mitral regurgitation was significantly higher in the RVA group (p=0.033), whereas the incidence of tricuspid regurgitation was similar in both groups (p>0.05). There was a trend toward less tricuspid regurgitation in the RVOT group however, it was not statistically significant. Ejection fraction was not significantly different between the study groups.
Conclusion: It seems that the incidence of mitral regurgitation in RVA pacing is significantly higher than RVOT although this needs further investigation in future studies.
Pariya Karampoor, Mahnaz Azarnia, Ghadireh Mirabolghasemi, Farzane Alizadeh,
Volume 17, Issue 5 (8-2014)
Abstract
Background: Fennel (Foeniculum vulgare) has estrogenic, anti-inflammatory and antioxidant effects and traditionally used for treatment of infertile women. Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in women, which affects 5-10% of them in their reproductive age. This study has examined the effects of hydroalcoholic extract of Fennel on female Wistar rats with PCOS.
Materials and Methods: In this experimental study, 30 rats (200 ± 20 gr), was injected 2 ml of estradiol valerate subcutaneously and 6 rats were considered as control(intact). After 60 days, the rats were divided into control, sham and experimental groups. Rats in experimental group were treated with 250, 500, 1000(mg/kg BW) of intraperitoneal injections extract of Fennel for 10 days. Serum FSH, LH and Testosterone were measured by ELISA and serum levels of these hormones between treatments all groups were compared using One-Way ANOVA at a significance level of p<0.05.
Results: The data suggests that extract of Fennel can increase serum concentrations of FSH and decrease LH and Testosterone in treatment groups. As FSH is 500 and 1000 mg/kg levels of doses, LH and Testosterone in dose 1000 mg/kg have shown statistically significant differences compared to control groups.
Conclusion: Considering the increasing positive effect of extract of Fennel on serum concentration of FSH and decreaseing LH and Testosterone in rats with PCOS, this compound might be considered for treatment of the patients.
Leila Akhtar Danesh, Zeinab Saiedi Nejad, Hossein Sarmadian, Alireza Amouzandeh-Nobaveh, Aliasghar Farazi, Ehsanollah Ghaznavi-Rad,
Volume 18, Issue 8 (11-2015)
Abstract
Background: Staphylococcus aureus is one of the important pathogens can cause infections in hospitals specially in intensive care units (ICU). It seems that nasal carriage is important risk factor for developing l infection at ICU units. This study was designed to investigate the frequency of S. aureus nasal carriage and its virulence in patients admitted to ICU units in Vali-Asr hospital at Arak university of medical sciences.
Materials and Methods: In this cross-sectional study, nasal swab samples were obtained from all the patients hospitalized in ICU unit of Vali-Asr hospital from July-December 2014 at admission. After identification, methicillin resistance and the frequency of pvl and acme genes determined by PCR. Demographic data were collected using questionnaire and were analysed using SPSS 20 software.
Results: Out of 390 patients, 81(20.8%) and 31(12.9) patients had been colonized with MSSA and MRSA, respectively. The result of culture was negative for 278 patients (71.3%). 77.4% of MRSA and 54.3% of MSSA isolates were positive for acme gene. Also, 11.11% of and 6.45% of MSSA MRSA isolates were positive for pvl gene.
Conclusion: The application of medical supportive devices like cv line, ventilator, history of surgery operation and antibiotic use significantly was associated with S. aureus nasal carriage. High prevalence of S.aureus shows that these bacteria settled in the hospital. Hence, infection control measures must be performed to reduce the risk of hospital infection.
Abdoreza Yavari, Farhad Fatehi, Hamid Dalvand, Akram Valizadeh, Rahmatollah Moradzadeh, Farideh Sadat Mirhoseini,
Volume 19, Issue 6 (9-2016)
Abstract
Background: The speech disorders may produce irreparable damage to childs speech and language development in the psychosocial view. The voice, speech sound production and fluency disorders are speech disorders, that may result from delay or impairment in speech motor control mechanism, central neuron system disorders, improper language stimulation or voice abuse.
Materials and Methods: This study examined the prevalence of speech disorders in 1393 Arakian students at 1 to 6th grades of primary school. After collecting continuous speech samples, picture description, passage reading and phonetic test, we recorded the pathological signs of stuttering, articulation disorder and voice disorders in a special sheet.
Results: The prevalence of articulation, voice and stuttering disorders was 8%, 3.5% and%1 and the prevalence of speech disorders was 11.9%. The prevalence of speech disorders was decreasing with increasing of student’s grade. 12.2% of boy students and 11.7% of girl students of primary school in Arak had speech disorders.
Conclusion: The prevalence of speech disorders of primary school students in Arak is similar to the prevalence of speech disorders in Kermanshah, but the prevalence of speech disorders in this research is smaller than many similar researches in Iran. It seems that racial and cultural diversity has some effect on increasing the prevalence of speech disorders in Arak city.
Fateme Niazi , Maryam Tehranipour, Khadije Shahrokhabadi,
Volume 19, Issue 7 (10-2016)
Abstract
Background: Angiogenesis is an important biological processes of new blood vessels in many pathological stages of development and embryo development occurs and a complex and dynamic phenomenon that is needed for development and other physiological processes. This study aimed to investigate the effect of alcoholic Ocimum basilicum leaf extract on angiogenesis chick chorioallantoic membrane is done.
Materials and Methods: In this experimental study 40 Ross fertilized eggs were randomly divided into four groups: control, sham-exposed and experimental groups were divided. The second day of incubation the eggs window was opened. Eighth day of the alcoholic extract of basil doses of 50 and 150 mg/kg on chick chorioallantoic membrane was injected. On day 12, embryos length and weight and chorioallantoic membrane (CAM) was photographed by photostereomicroscope Then the numbers and lengths of vessels in special area on CAM were measured with Image J. analyzed through by t-test and ANOVA (P<0.05).
Results: The data does not show significant difference between embryos length and weight in sham compare to all experimental groups. In the study vessels number just with 150 mg/kg observed significant.
Conclusion: Alcoholic extract of basil is an increase in the number of vessels and in this sense the healing and growth processes associated with them as well as effective.
Esmaeil Fattahi, Vahid Hemayatkhah Jahromi ,
Volume 19, Issue 8 (11-2016)
Abstract
Abstract
Background: Eryngium caucasicum Trautv has antioxidant properties due to the presence of flavonoids and phenolic compounds. So, the present study was done to investigate the protective effects of Eryngium caucasicum Trautv extract on tricyclazole induced hepatotoxicity in mice.
Materials and Methods: In this experimental study, 42 mice were divided into 6 groups including control, sham, tricyclazole (TCZ) and three experimental groups. The mice in the tricyclazole group, received 50 mg/kg TCZ via intraperitoneal injection and experimental groups 2, 3 and 4 received respectively 100,200and 400 mg/kg of extract via gavage for 4 weeks and 2 days per week. The sham group received only sterile water. At the end, serum levels of ALT, AST and ALP, serum concentration of albumin and total bilirubin were measured. Also, total phenolic compounds and flavonoids in the extract were measured. Data were analyzed by using ANOVA.
Results: Tricyclazole increased serum levels of aminotransferase, phosphatase alkaline and total bilirubin and decreased serum concentration of albumin. But, treatment with extract decreased liver enzymes and bilirubin and increased levels of albumin (p<0.05). Amount of total phenolic compounds and the flavonoids were measured 91.16 mg/gr galicacid in extract and 84.48 mg/gr quercetin in extract, respectively.
Conclusion: The results demonstrated that Eryngium caucasicum Trautv extract due to the presence of high phenolic compounds has protective effects on tricyclazole induced hepatotoxicity.
Ali Arjmand Shabestary, Mahmoud Khaloei, Mohammad Arjomandzadegan, Zahra Eslamirad, Reza Ghasemikhah,
Volume 20, Issue 8 (11-2017)
Abstract
Abstract
Background: Resistance of Acanthamoeba cysts causes recurrence of the disease; so, the patient should be monitored regularly ،The aim of the study was to examine the effect of a few herbal materials on Acanthamoeba cysts in vitro.
Materials and Methods: Essential oils (EOs) of Zataria, Mint, and Oregano were prepared by steam distillation. The EOs and Hypericum perforatum extract were prepared in three concentrations (0.6%, 1% and 10%)، Acanthamoeba cysts in various time intervals (30, 60, 120, 180 and 1440 minutes) were exposed with plant extracts. Then, the viability of parasite was investigated by eosin 0.1%.
Results: Comparison of the parasite mortality rate between control and case groups showed that the mortality of Acanthamoeba cysts was higher in the case groups that exposed to herbal materials. At the equal concentration (10%) and time (24 h), the Zataria and mint EOs produced the highest (22%) and lowest (4%) mortality, respectively. The results showed the mortality rate of Acanthamoeba was time-dependent.
Conclusion: Zataria showed the most fatality effect against Acanthamoeba cysts. In this respect, clinical trial studies are suggested.
Fatholah Mohaghegh , Mehran Mohseni, Nasrin Robatmili, Mohamad Reza Bayatiani , Fatemeh Seif, Nayyer Sadat Mostafavi,
Volume 21, Issue 6 (12-2018)
Abstract
Background and Aim: Radiation therapy is the destruction of cancer cells that in all patients with breast cancer reduces tumor recurrence, relieves pain in local tumors and metastases. There are different treatment methods around the world such as electron, photon alone or a combination of both types of fields.
Materials and Methods: In this study, photon therapy (PT) and mixed photon-electron therapy (MPET) were used to treat malignancies of the supraclavicular lymph nodes. 30 patients with right-sided breast cancer with local lymph node metastasis were recruited. The ISOgray software was utilized to collect data about treatment planning methods with PT and MPET.
Findings: The maximum and mean delivered doses of radiation to the supraclavicular region were 52.08±1.64, 42.59±0.51 Gy and 54.24±1.64, 43.67±0.43 Gy in the PT and MPET methods, respectively. The mean irradiated volumes of supraclavicular fossa that received 90% of the radiation dose were 59.74±1.94% and 70.26±0.94% in the PT and MPET methods, respectively (p=0.004). The maximum doses delivered to the spine were 14.66±1.9 Gy and 10.22±0.92 Gy and the thyroid were 42.62±3.1 Gy and 37.67±5.02 Gy in the PT and MPET methods, respectively.
Conclusion: The maximum doses delivered to the spine and thyroid significantly diminished by the novel method. Additionally, supraclavicular region received higher maximum and mean doses in the new treatment modality compared to the conventional methods. The new method improved dose coverage for the tumor.
Mohammad Amin Edalatmanesh, Habibollah Khodabandeh, Nooshin Yazdani, Samaneh Rafiei,
Volume 21, Issue 6 (12-2018)
Abstract
Background and Aim: Neuropathy is the most common abnormality in diabetes mellitus which characterized with cerebral damages especially in hippocampus. This study evaluates the effect of Cinnamomum Zeylanicum extract (CZE) on memory, hippocampal neuron damage and antioxidant enzymes levels in animal model of diabetes.
Materials and Methods: 50 adult Sprague dawley rats were randomly divided into 5 groups: Control, STZ (Streptozotocin, 50 mg/kg; i.p.), and STZ + CZE100, STZ + CZE200 and STZ + CZE400 which were treated with CZE in 100, 200 and 400 mg/kg, respectively. CZE was administered in 14 days, orally. After evaluation of working and spatial memory, activity of catalase (CAT) and glutathione peroxidase (GPx) enzymes was assessed by ELISA. Then, histopathological assessment of hippocampus was done.
Findings: In comparison with the controls, STZ group showed an increase in latency time and distance to the hidden platform in MWM, a decrease in alteration behaviors, cell density and activity of CAT and GPx enzymes in hippocampus (p˂0.05). In addition, treatment with CZE decreased latency time and distance in MWM and increased alteration behavior, hippocampal cell density and activity of antioxidant enzymes in comparison with the STZ group (p˂0.05).
Conclusion: Diabetes with reduction of neuronal density and activity of antioxidant enzymes in the hippocampus causes deficits in spatial and working memory. However, Administration of CZE ameliorates these neuropathologic disorders.
Farzaneh Jajarmi, Ahmad Jonidi Jafari, Majid Kermani, Mitra Gholami,
Volume 22, Issue 1 (4-2019)
Abstract
Background and Aim: Dust was considered by researchers as one of the most important forms of air pollution. The aim of this study was to identify the physical and chemical characteristics of dust storm sources in Tehran.
Materials and methods: This study was conducted in selected air sampling stations of Tehran, in the days of dust and ordinary from January 2016 for one year. The concentration of dust particles was determined by gravimetric. Heavy metal concentrations in samples after digestion were determined with graphite furnace atomic absorption spectrometry (AAS-GF). Mineralogy and morphology of the dust fall particles were inspected using X-ray diffraction and scanning electron microscopy and sources particles using Enrichment Factor Analysis and principal component analysis (PCA) were performed. For statistical analysis, R software was used.
Ethical Considerations: This study with research ethics code IR.IUMS.REC.1397.313 has been approved by research ethics committee at Iran University of Medical Sciences.
Findngs: The highest average particle concentration in normal days was related to the central station (122.63 µg / m3), and the lowest for the East Station (67.13 µg / m3). The highest concentrations of the elements measured in the particles are related to iron and aluminum and the lowest concentrations of chromium and nickel. Lowest amount of Enrichment Factor was obtained for iron, less than one.
Conclusion: The results of this study indicated that the concentration of dust in center was higher than other station. Natural and human resources both play a significant role in the release of metals. By conducting further studies on the source of dust in Tehran and using the results, effective control measures can be designed and implemented.
Seyed Ali Kazemi Rezaei, Sahar Khoshsorour, Robabeh Nouri,
Volume 22, Issue 4 (9-2019)
Abstract
Background and Aim Obesity with its various physical and mental problems threatens public health. This study aimed to investigate the discriminative role of metacognitive beliefs, the difficulty in emotion regulation, and codependency in women with obesity.
Methods and Materials In this causal-comparative research, 40 obese women (BMI ≥30 kg/m2) and 40 normal-weight subjects were selected by convenience sampling method. The samples were evaluated by metacognitive questionnaire, difficulties in emotion regulation scale, and the Farsi version of codependency measurement tool. We used discriminant function analysis to analyze the obtained data.
Ethical Considerations All study subjects signed the written consent form. The Research Ethics Committee of Kharazmi University approved this study (Code: IR.KHU.REC.1397.41).
Results The discriminant function could correctly classify 95% of obese people and 97.5% of normal-weight people with 3 variables of metacognitive beliefs, difficulty in emotion regulation, and codependency. In other words, 96.25% of all participants had been classified correctly.
Conclusion Distinguishing the two groups of obese and normal people, the variables of metacognitive beliefs, difficulty in emotion regulation, and codependency have a significant role. Therefore, these variables are supposedly influential psychological factors in obesity. So they can be used for its prevention and treatment.
Seyed Hamed Mirhoseini, Fatemeh Ariyan, Samaneh Mohammadi,
Volume 22, Issue 6 (1-2020)
Abstract
Background and Aim: The assessment of indoor air quality and detection of its microbial pollutants in classrooms is very important because of the presence of children sensitive to these pollutants. The aim of this study was to determine the concentration and characterization of dominant species of biological aerosols and their relationship with environmental factors in two selected primary schools in Arak, Iran.
Methods & Materials: This cross-sectional study was conducted at two primary schools in Arak, Iran in Fall 2018. Indoor air sampling was performed using single-stage Andersen microbial sampler (at flow rate of 28.3 liters/min) containing bacterial and fungal culture media. The effects of suspended Particulate Matter (PM) and environmental parameters (temperature and humidity) on the density of bioaerosols were evaluated.
Ethical Considerations: This study with an ethics code of IR.ARAKMU.REC.1397.76 was approved by the Research Ethics Committee at Arak University of Medical Sciences.
Results: The overall mean density of indoor bacteria and fungi was 448 cfu/m3 and 394 cfu/m3, while the mean density of outdoor bacteria and fungi was 210 cfu/m3 and 127 cfu/m3, respectively. There was a positive correlation between indoor density of airborne bacteria and suspected PM concentrations (PM 10 and PM 2.5), and between PM2.5 concentration and indoor fungal density (P<0.05). Penicillium (40%), Cladosporium (19%) and Aspergillus (16%) were dominant species of fungi, while Staphylococcus (42%), Micrococcus (28%), Bacillus (21%) were the dominant species of bacteria.
Conclusion: The age and type of building and the density of students in a classroom are the main factors in increasing the concentration of bioaerosols.
Fatemeh Momeni, Afrooz Nakhostin, Mojtaba Bayani,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: Periostin acts as necessary protein in tissue development and has a key role in tooth-supporting tissues such as periodontal ligament. The effect of inflammation on reducing periostin level has been shown in some studies. The aim of this study was to compare the salivary and Gingival Crevicular Fluid (GCF) periostin levels in patients with chronic periodontitis and healthy peers.
Methods & Materials: In this matched case-control study, 106 participants (53 patients with chronic periodontitis and 53 healthy controls) were studies after signing a informed consent form. They were matched for age, gender, weight, and Body Mass Index (BMI). The GCF and salivary samples were collected from all participants and were assessed using standard Enzyme-Linked Immunosorbent Assay (ELISA). The statistical analysis was conducted in Stata V. 11.
Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.34).
Results: The salivary and GCF periostin levels was significantly lower in patients than in healthy subjects (P<0.001). Moreover, the periostin levels was significantly different based on periodontal parameters (P<0.001).
Conclusion: There is association between the incidence of chronic periodontitis and salivary and GCF periostin levels. Hence, the periostin may act as a potential biomarker for the diagnosis of chronic periodontitis and prevention of its progression.
Raheleh Firouzi, Taher Tizdast, Javad Khalatbari, Shohreh Ghorban Shiroudi,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: The purpose of this study was to evaluate the relationship between stress coping strategies and difficulties in emotion regulation mediated by marital life quality in married women with breast cancer.
Methods & Materials: This is a descriptive correlational study. The study population included all married women with breast cancer in Amol and Babol cities of Iran in 2018. Of these, 385 were selected through a convenience sampling technique. The research instruments were Ways Of Coping Questionnaire, Difficulties In Emotion Regulation Scale and Marital Life Quality Scale. The goodness-of-fit of proposed model was examined by Structural Equation Modeling (SEM) in LISREL software. The indirect correlations were tested by using Preacher and Hayes’ bootstrapping method .
Ethical Considerations: This study received its ethical approval from Islamic Azad University of Tonekabon Branch (Code: IR.IAU.TON.REC.1397.029). Informed consent was obtained from all participants.
Results: The proposed model had good fit (RMSEA=0.057). All direct correlations were reported significant (P<0.05). Moreover, indirect paths between stress coping strategies and difficulties in emotion regulation through mediation by marital life quality were significant.
Conclusion: The proposed model had a good fit and can be used in identifying the factors affecting difficulties in emotion regulation. It can be useful for designing and developing programs to prevent emotions problems in women with breast cancer.
Ensieh Seif Amirhoseiny, Ali Ganji, Ghasem Mosayebi, Ali Ghazavi,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: Fennel with phytoestrogenic, antioxidant and anti-diabetic properties is used in traditional Iranian medicine to treat Polycystic Ovarian Syndrome (PCOS). Chronic inflammation is a new proposed mechanism in PCOS pathogenesis that suggests the role of immune system in this disease. Due to the main role of Treg cells in maintaining immune homeostasis, their impaired function, along with increased production of inflammatory compounds such as nitric oxide, can lead to persistent inflammation.
Methods & Materials: In this experimental study, 18 BALB/c mice were randomly divided into three groups including control group, untreated PCOS-induced group, and fennel-treated group. The control group received 0.1 ml sesame oil for 21 days. PCOS was induced by subcutaneous injection of Dehydroepiandrosterone (60 mg/kg/day) plus 0.1 mL sesame oil for 21 days. Mice in third group were treated by intraperitoneal injection of 500 mg/kg/day fennel extract after 21 days. The regulatory of T cells (Tregs) were analyzed by flow cytometry method and nitric oxide level determination was performed by Griess Reaction method. Ferric Reducing/Antioxidant Power (FRAP) assay was used to measure the total antioxidant power.
Ethical Considerations: This study was approved by the Ethical Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.312).
Results: The estrous cycle was normalized after treatment with fennel. Fennel significantly reduced the number of ovarian cysts. Nitric oxide concentration decreased significantly while FRAP concentrations did not significantly alter. The number of Treg cells was also increased significantly.
Conclusion: Due to the role of immune system in the incidence of inflammation, concurrent modulation of both immune and endocrine systems may open new horizons in the design of new therapeutic interventions for PCOS.
Zakiyeh Gharib, Naser Sanchooli, Nima Sanadgol,
Volume 23, Issue 2 (5-2020)
Abstract
Background and Aim: This study aimed to investigate the association between Endoplasmic Reticulum autophagy (ER-phagy) and Alzheimer’s Disease (AD) by analyzing the expression patterns of related genes in animal models.
Methods & Materials: Microarray data of AD patients’ brain tissues were extracted from the Gene Expression Omnibus (GEO) database. These data were first analyzed in GEO2R online tool. Then, the expression of ER-phagy related genes were isolated and the protein interaction networks were plotted by STRING database for the genes with increased expression. Finally, the relationship between the genes that had significant increased expression were designed, and the expression of new identified genes in each study was examined.
Ethical Considerations: All ethical principles were considered in this article.
Results: Genes involved in ER-phagy showed a sporadic expression in different AD models. An increase in the expression of ER-phagy regulatory 1 (FAM134B) gene was observed in studies with the mutation in both Microtubule-associated Protein Tau (MAPT) and Amyloid Precursor Protein (APP) genes. Increase in the expression of NPC intracellular cholesterol transporter 1 (NPC1) gene was observed in two studies that had mutations in APP, Presenilin 1 (PSEN1) and MAPT genes. Moreover, SEC62 homolog and Cell Cycle Progression 1 (CCPG1) genes both showed decreased expression in one study. Finally, the expression of Reticulon 3 (RTN3) was not significant in any of the studies.
Conclusion: The genes involved in ER-phagy have a sporadic expression in AD models, where only two genes FAM134B and NPC1 are involved in AD. The FAM134B gene seems to interact with the Wnk1 gene, which plays a role in cell survival and proliferation, in the hippocampus and forebrain. It also interacts with the Map1lc3b gene, which has a role in phagosome deletion and protein ubiquitination, in the forebrain. It also interacts with the Map1lc3b gene, which has a role in phagosome deletion and protein ubiquitination, in the forebrain. NPC1 had interaction with the Abcg1 gene, which activates lipid homeostasis, in the subventricular zone.
Dr Mehdi Zemestani, Mrs Azam Saidian,
Volume 26, Issue 1 (4-2023)
Abstract
Introduction: Since dermatologic diseases are relatively high prevalent in the society and are associated with various psychological consequences, the present study was conducted to compare the difficulties in emotion regulation, psychological flexibility and quality of life in dermatologic patients with Lichen Simplex Chronicus and normal population.
Methods: The study design was causal-comparative, and the statistical population included all men and women with dermatologic diseases who referred to skin clinics in Tehran, Karaj and Qom cities. A convenience sampling method was employed to select 199 patients as the study sample. In addition, for the comparison group 200 normal individuals were selected from normal population. All participants assessed by the Difficulties in Emotion Regulation Scale (DERS), Acceptance and Action Questionnaire-II (AAQ-II), and Short Form-36 Quality of Life (SF-36). Data were analyzed by Multivariate Analysis of Covariance (MANCOVA). This study was approved by Research Ethics Committee of University of Kurdistan (Code: IR.UOK.REC.1401.015).
Results: Results showed that there was significant difference between two groups in terms of difficulties in emotion regulation, psychological flexibility and quality of life. The mean scores of difficulties in emotion regulation scale and psychological flexibility were higher in the patient group and lower in quality of life than the healthy group.
Conclusions: According to the present results, psychological factors of emotional dysregulation and psychological inflexibility may play a role in the persistence of skin problems of Lichen Simplex Chronicus. Since psychological underlying factors are often involved in the development and maintenance of dermatologic diseases, it is suggesting to use psychological interventions for these patients at the same time.
Dr Sina Banijamali, Dr Oldooz Aloosh, Dr Vahan Moradians, Dr Tayeb Ramim, Dr Haleh Afshar,
Volume 26, Issue 3 (9-2023)
Abstract
Introduction: Patients with COVID-19 can have various and complex coagulation disorders that cause hypercoagulable conditions. Investigating the role of anticoagulants with different doses in the outcome of patients with COVID-19 seems to be needed. Therefore, the present study was conducted with the aim of predicting factors of severe disease, including the number of lymphocytes, LDH, and the recovery status of patients.
Methods: A cross-sectional study was conducted in patients with COVID-19 hospitalized in Hazrat Rasool Akram (PBUH) Hospital. Study entry includes acute respiratory symptoms caused by COVID-19 disease (uncontrollable cough, dyspnea, prolonged medicine and blood saturation drop) along with lung involvement in chest spiral CT scan without injection, SARS RT-PCR–CO virus test was positive and transfer to intensive care unit (ICU) was indicated. Anticoagulant starting time, type and dose of anticoagulant received and duration of use were recorded. Two groups of prophylaxis dose, higher dose than prophylaxis (medium dose and therapeutic dose) were divided.
Results: Out of the total number of patients referred to Rasul Akram Hospital, 90 people (43 women (47.8%) and 47 men (52.22%)) participated in this study. The average hospitalization in the ICU was 13.50 ± 12.39 days and 17.18 ± 13.36 days in the hospital. Also, the duration of coagulant therapy was 17.13 ± 13.38 days. 53 patients (58.9%) received a prophylactic dose, 28 patients (31.1%) received a therapeutic dose, and 9 patients (10%) received a moderate dose of anticoagulant. Anticoagulant in 74 patients (82.2%) was unfractionated heparin (UFH) and in 16 cases (17.8%) low molecular weight heparin (LMWH). The changes of LDH, number of lymphocytes, dimer, fibrinogen, ferritin and FDP according to the dose of anticoagulant assessed in the three groups of prophylaxis, treatment and no statistically significant difference. The mean of ICU admission days according to different doses of anticoagulant did not show a statistically significant difference.
Conclusions: Finally, the findings obtained from the study showed that the use of different doses of anticoagulant does not cause a difference in the level of LDH, number of lymphocytes, ferritin and FDP at different measurement times. Also, the length of stay in the hospital and the time of hospitalization in the intensive care unit did not differ between the groups receiving prophylactic anticoagulant, medium dose and therapeutic dose.
Amir Hossein Zahirnia, Amir Lorzadeh, Hassan Nasirian, Behroz Davari,
Volume 26, Issue 6 (2-2024)
Abstract
Introduction: Head lice (Pediculus capitis) infestation is considered an important hygienic problem in developing countries. The aim of study was to compare 1% permethrin shampoo and 4% dimethicone lotion effects for treatment of infected head lice students in primary girl schools in Gotvand County, Khuzestan province.
Methods: The studied population was first- to sixth-grade students in elementary schools. Positive cases with head lice after identification (304 persons) were randomly divided into two treatment groups. Permethrin shampoo and dimethicone lotion were allocated for the first and the second groups, respectively. The drug therapeutic effects were studied after 7, 14 and 21 days after treatment. Data were analyzed by Chi-square test using SPSS software.
Ethical Considerations: This study was approved by the Ethics Committee of Hamadan University of Medical Sciences (Code: IR.UMSHA.REC.1399.778).
Results: In total, 304 students participated in the study. The age of students ranged between 7 and 12 years which 47.7% of them were between 7 and 8 years. Also 60.9 and 39.1% of them were in urban and rural schools, respectively. The drug effectiveness were 46.1, 69.5 and 100, and 77.6, 85.3 and 100% for permethrin and dimethicone in the first, second and third intervals after treatment, respectively. There was a significant difference between the effect of drugs in the first interval (P = 0.00) after treatment but there was not a significant difference between the second (P = 0.084) and the third (P = 0.43) intervals after treatment.
Conclusions: It is recommended the use of dimethicone lotion and permethrin shampoo as the first and second option, respectively in eliminating the head lice infestation in primary girl schools.
Zahra Sadat Mousavi, Fatemeh Nasernakhaei,
Volume 27, Issue 6 (1-2025)
Abstract
Introduction: Bird′s-foot trefoil (Lotus corniculatus L., Fabaceae) has many medicinal properties due to its valuable chemical compounds. This research reviews the chemical compounds and medicinal properties of this plant.
Methods: This study used library resources, search engines, and databases such as Google, Google Scholar, PubMed, PubChem, ScienceDirect, Magiran, ResearchGate, and SID. The data were collected and classified.
Results: The results indicate that bird′s-foot trefoil is rich in valuable compounds such as kaempferol, quercetin, isorhamnetin, oleamide, and linoleamide. Different extracts of this plant have antioxidant, anti-inflammatory, immunostimulant, anti-cancer, anti-pain, anti-depressant, anti-amylase, anti-fungal, antiprotozoal, and anti-bacterial activities. It is used for wound healing, controlling anxiety and nausea, treating urinary infections, removing kidney stones, and as an antispasmodic and anti-hemorrhoid. Topical application of Lotus corniculatus seed extract has reduced the sebum contents and areas of oily human skin.
Conclusions: L. corniculatus can directly and indirectly affect human life and health. Due to the effective compounds and medicinal properties of Bird′s-foot trefoil, additional studies and clinical tests on its medicinal properties should be performed.
