Somayeh Dehghani , Ahmad Jonidi Jafari, Mahdi Farzadkia, Mitra Gholami,
Volume 15, Issue 7 (12-2012)
Abstract
Background: Nowadays, international concern about the impact of antibiotic residues on the environment increased and their removal has received a lot of consideration. The aim of this study was to investigate the efficiency of Fenton’s advanced oxidation process (H2O2/Fe+2) in sulfadiazine antibiotic removal from aqueous solutions. Materials and Methods: An experimental-laboratory scale study was done on a synthetic wastewater containing sulfadiazine antibiotic with 0.079, 0.19, and 0.47 mM concentrations under Fenton’s process. Then optimal values of affecting parameters, such as initial antibiotic concentration, molar ratio of reagents, [Fe+2] and [H2O2] concentration, detention time, and pH, were determined. The discharged effluent analyzed by HPLC-UV to identify the antibiotic residues. Results: The results showed that the optimal parameters in the Fenton’s oxidation process to remove the sulfadiazine included antibiotics at pH 3.5, molar ratio of [H2O2] / [Fe +2] equal to 1.5, and contact time of 15 minutes, respectively. In these optimal conditions, the efficiency of removal of antibiotic in concentrations of 0.079, 0.19, and 0.47 mM were 99.82%, 97.97% and 78.23% and the wastewater COD removal degrees were 83.33%, 78.57%, and 78.57%, respectively. Conclusion: The experiments showed the efficient removal of sulfadiazine antibiotic in wastewater by Fenton’s oxidation process. The efficiency of this method can also be considered in eliminating other antibiotics resistant to biological treatment
Reza Tajik, Hasan Asilian Mohabadi, Ali Khavanin, Ahmad Joneidi Jafari, Ardalan Soleimanian,
Volume 15, Issue 8 (1-2013)
Abstract
Background: Poly chlorinated biphenyls (PBCs) are the group of organic chemical materials that have a great chemical stability. These compounds are hazardous pollutants which pose various occupational and environmental problems. This study was conducted to determine the effect of microwave rays, hydrogen peroxide, Tio2 catalyst, and ethanol on the decomposition of PBCs. Materials and Methods: In this experimental study, a vessel reactor (250ml volume)that was connected with a tube connector to thecondensor system was used. A microwave oven with a fixed frequency of 2450 MHZ was used to provide microwave irradiation and ray powers used at 540, 720 and 900w. pH and temperature of the samples were continuously monitored and the experiments were repeated three times. Askarel oils were analyzed by GC-ECD. Results: The mean of total PCBS degradation at 540, 720, and 900w was 83.88±1.63, 89.27±2.44, and 95.98±0.81%, respectively. The mean of total PCBS degradation in terms of ratio to solvent with oil transformer in 1:1, 2:1, and 3:1 was 53.8±3.26, 79.04±1.24, and 95.08±1.69%, respectively. The mean of total PCBS degradation in terms of not using H2o2/Tio2 and using H2O2 (20%) and 0.05, 0.1, 0.15, and 0.2 g of Tio2 concurrently was 71.47±0.81, 87.9±2.16, 89.48±1.69, 91.7±1.24, and 93.07±3.09 %, respectively. Conclusion: Using microwave irradiation in the presence of H2O2 oxidant and Tio2 catalyst leads to the reduction of PCBS.
Nasrin Roozbahani, Fazlallah Ghofranipour, Hossein Eftekhar Ardabili , Ebrahim Hajizadeh,
Volume 15, Issue 9 (2-2013)
Abstract
Background: Postpartum women are a population at risk for sedentary life. Previous studies have shown that self-efficacy is an important determinant of stage of change and exercise adherence. This study evaluates the relationship between self-efficacy and stage of change and physical activity (PA) behavior in Iranian mothers. Materials and Methods: In this cross-sectional study, 300 postpartum mothers were selected randomly from all health centers in Arak. The instruments used in this study included the 7-day PA recall, stages of exercise adoption tool, and self-efficacy for exercise scale. Data analysis was performed using SPSS software. Results: Ninety-one percent of the participants were in the pre-contemplation, contemplation, and preparation stages of change. Mean score for moderate PA was 38.94±40.5 minutes a week. Significant relationships were found between the stages of PA behavior change and METs of weekly energy expenditure from moderate activities (r=0.60, P<0.001). Also, statistically significant relationships were found between self-efficacy and the stages of PA behavior change (r=0.50, P<0.001) weekly energy expenditure from moderate activities (r=0.40, P<0.001), and pre-pregnancy PA behavior (r=0.39, P<0.001). Conclusion: The level of PA of the participants was less than the recommended minimum level for regular PA behavior (150 minutes of moderately intense PA per week). In this population, self-efficacy plays an important role in PA behavior and it should be taken into consideration in designing interventions for improving PA behavior.
Farzad Nazem, Mojtaba Izadi, Majid Jaliliu, Behzad Keshvarz,
Volume 15, Issue 9 (2-2013)
Abstract
Background: Epidemiological studies have shown the relationship between incidence of asthma symptoms and environmental factors, such as sedentary lifestyle and metabolic and cardiovascular diseases. However, the role of exercise rehabilitation protocols on lung function in obese adult patients with chronic asthma is a controversial issue. The aim of the present study is to evaluate the impact of aerobic exercise on lung function in obese middle-aged men with chronic asthma. Materials and Methods: This semi-experimental study was conducted on 39 obese middle-aged males with mild and moderate asthma. The experimental group (n=19) with regard to the safe range 15≥ RPE>9 followed the sub-maximal rehabilitation exercise program (50 to 80% HRmax intensity) for 3 months. Then, they underwent one month of detraining. The control group (n=20) did not have any form of aerobic exercise. Spirometric parameters in base, three months of training, and one month of detraining were measured by standard methods. Results: Indicators of lung function, including FVC, FEV1/FVC, PEF, FEF%75, and MVV significantly decreased. The pattern of changes in FEV1, FEV1/FVC, and MVV remained stable even after a month of detraining (p<0.05). However, no significant changes occurred in the dependent variables of the control group (p>0.05). Conclusion: It seems that the incidence of physiological adaptations of aerobic exercise, as a non-pharmacologic clinical factor, after the one-month detraining period affected the spirometric parameters in obese asthmatic patients
Behroz Karimi, Mohamad-Sadegh Rajaei, Mohammad Javad Ganadzadeh, Masoumeh Mashayekhi, Mostafa Jahanbakhsh,
Volume 15, Issue 10 (3-2013)
Abstract
Background: The presence of nitrate in drinking water causes various health and environmental problems. The aim of this study was to evaluate the efficacy of nitrate reduction by Fe/H2O2 process and adsorption on activated carbon. Materials and Methods: This experimental study investigated nitrate oxidation by advanced oxidation process of Fe°/FeІІ/FeШ/H2O2 at pH 2-10, nitrate concentrations of 50-300 mg/L. After adjusting the pH, 0.5, 1, 2, 5, and 10 g/L values of GAC, PAC, H2O2/GAC, and Fe/H2O2/GAC together with H2O2 at retention times of 15, 30, 45, 60, and 90 minutes, respectively, were added and mixed. Results: At retention time of 10 minutes and 0.5 mL H2O2 and 1 g/L from Fe°, FeІІ, and FeІІІ, the removal efficacy was 88.5, 84 and 78%, respectively. At 50 mg/L nitrate and 0.5, 1, and 10 mg/L GAC concentrations, the removal efficacy was 56.5, 93.6, and 82.6%, respectively. The nitrate removal efficiency at pH=4 was approximately 50%, whereas at pH=3 with 30% efficacy, it increased to 80%. Conclusion: Modified Fe/H2O2 process with iron nano-particles and activated carbon adsorption can effectively reduce nitrate under optimal conditions. The use of activated carbon at a concentration of 1 g/L increased the removal efficiency of nitrate to 90%.
Mahin Farahmand, Amir Almasi-Hashiani, Davood Mehrabani,
Volume 15, Issue 10 (3-2013)
Abstract
Background: Prostate cancer is one of the most common cancers in men which its incidence rate and associated mortality and morbidity are on the rise. The aim of this study was to investigate the epidemiology of prostate cancer in Fars province between 2003 and 2008 years. Materials and Methods: In this epidemiological study, using Fars province cancer registry data, the incidence rates were calculated per 100,000 people and age standardized incidence rate (ASR) was measured by direct method using the world standard population. Data were analyzed by SPSS, version 16, and Microsoft Excel, version 2007. Cochrane Armitage Test for linear trend was used for evaluation of the incidence trend by running Winpepi software. Results: Over a 6-year period, 1212 cases were recorded in Fars province. The ASR of prostate cancer in these six years was 4.69, 7.16, 15.09, 14.04, 16.65 and 16.02, respectively, which revealed significantly increasing trends. The highest incidence rate was observed in 80 and upper age group. Conclusion: The ASR of prostate cancer in Fars province is significantly lower than other parts of the world, especially in more developed countries. This can be due to absence of screening programs and/or cancer registry.
Abbas Saremi, Nader Shavandi, Mona Dezfolian,
Volume 16, Issue 2 (5-2013)
Abstract
Background: Anti-mullerian hormone (AMH) is a reliable marker for ovarian reserve and fertility capacity. The aim of this study was to investigate the differences in AMH between physically active and non-active women.
Materials and Methods: Eighty two reproductive age women (18-50 years) participated (42 active and 40 non-active) in this cross-sectional study. Physical activity level was estimated via the International Physical Activity Questionnaire. Information on fertility parameters were obtained from medical records. Serum AMH was measured using ELISA assay.
Results: There was not a significant difference in mean age between the two groups (P>0.05). There was a significant difference between physically active and non-active women regarding basal concentration of serum exercise AMH (3.90±0.75 ng/ml versus 1.63±0.53 ng/ml, respectively) (P<0.03). Abortion rates differed significantly (P<0.05) between physically active (0.13±0.26) and non-active women (0.40±0.51).
Conclusion: These findings indicated that physical activity may improve fertility capacity in healthy women by maintaining AMH.
Maryam Azizpour, Davood Hosseini, Hossein Basiri, Neda Akbari, Mitra Nezamabadi, Saber Eskandari, Mohsen Sarikhani,
Volume 16, Issue 3 (6-2013)
Abstract
Background: Brucellosis is a debilitative disease that imposes heavy costs on the economy and society. Therefore, using the most accurate and efficient method to diagnose this disease is essential. In Iran, Brucella melitensis is the common causative agent for brucellosis and BP26 protein of this bacterium has a good level of antigenicity. Thus, the aim of this study is to produce Brucella melitensis recombinant BP26 protein with a PET28a expression vector.
Materials and Methods: In this applied-fundamental study, genomic DNA was isolated from bacterial culture through proteinase K (pK) and phenol/chlorophorm protocol. Then, two pairs of primers were designed based on the known sequence in the gene bank for amplification of Brucella melitensis bp26 gene and PCR reaction was set up and optimized. The PCR product was cloned first into PTZ57R/T vector and accessed on the PET28a vector and sequenced. The recombinant vector was transformed and expressed into E. coli BL21 (DE3). Then, the recombinant protein was purified with Ni-NTA column of chromatography against His tag.
Results: The size of PCR product was in accordance with the part of bp26 gene size in the gene bank. The bp26 gene without adding IPTG had little expression and 3 hours after adding IPTG with a 1 Mm concentration to culture media, extreme expression was observed.
Conclusion: The production of recombinant BP26 protein from isolated Brucella melitensis native to Markazi province was done. Noticing the importance of BP26 protein and its significance for future studies on providing brucellosis diagnosis kits, its production was made possible.
Mohamad Sadeg Rajaei, Zahra Salemi, Behrooze Karimi, Mohammad Javad Ghanad Zadeh, Masoomeh Mashayekhi,
Volume 16, Issue 3 (6-2013)
Abstract
Background: Today, global concerns about water pollution with chemicals and its adverse impact on health have increased. This study aims to evaluate the physical and chemical quality of water treated through domestic water treatment systems.
Materials and Methods: In this cross-sectional descriptive study, water samples were collected from 60 domestic water treatment systems and parameters, such as turbidity, total dissolved and suspended solid, total hardness and calcium, magnesium hardness, alkalinity, total alkalinity, carbonate, bicarbonate, nitrate, sulfate, nitrite and fluoride, EC, pH, and free chlorine residuals, were examined.
Results: The results indicate that the average concentration of chemical parameters in treated water were: chloride=0.1mg/L, nitrate=0.006mg/l, sulfate=5 mg/l, Nitrate=15mg/L, bicarbonate=49 mg/L, calcium hardness=18 mg/L, and fluoride=0 mg/l.
Conclusion: The overall results of this study indicated that the use of municipal water treatment reduced Cl2, sulfate, and bicarbonate concentrations than the optimal levels in urban areas water. However, nitrite concentration was significantly higher in the output of these systems than distribution systems, which is a source of concern.
Babak Eshrati, Seyed Shahriar Hosseini, Mohsen Farahani, Mahin Sadat Azimi, Maryam Zamanian,
Volume 16, Issue 4 (7-2013)
Abstract
Background: Funnel plot is a graphical tool for investigating publication bias in meta-analysis studies. The aim of this study is to introduce another application of funnel plot that is monitoring one of the Iranian family performance indices and determining the position of each health center of Markazi province in terms of patient referral rates by general practitioners to specialists and to compare it with bar and caterpillar plots.
Materials and Methods: In order to draw the funnel plot, the average monthly percent of referrals for each district of Markazi province in 2011 was computed. In this study, Iranian Ministry of Health and Medical Education standard figure of 10% was considered as the limit of referral to the second level of Iranian health services. The 99% confidence interval of the control limit for each district was computed according to 3 standard deviations of the percent of referrals relative to the total patient visits.
Results: Based on funnel plot results, five out of ten districts were in the expected range of referral (Ashtian, Saveh, Tafresh, Khomein, and Komijan). However, in other five districts, the referral rate was greater than the expected rate (Arak, Shazand, Zarandiyeh, Delijan, and Mahallat). Mahallat district had the highest rate of referral.
Conclusion: The funnel plot was more informative than the other two plots Thus, it can be viewed as a useful tool in monitoring health programs throughout the country.
Majid Motamedzade , Ali Dormohammadi, Hosein Amjad Sardrodi , Esmaeil Zarei , Reza Dormohammadi, Masoud Shafii Motlagh,
Volume 16, Issue 6 (9-2013)
Abstract
Background: Load lifting is the most stressful activity of the Manual Material Handling and can trigger of work-related musculoskeletal disorders of workers. Purposes of this study are determining the prevalence of musculoskeletal disorders, assessment lifting tasks by NIOSH lifting equation method, ergonomic design and assessment of its effectiveness.
Materials and Methods: This analytical and interventional study was performed on 30 workers in a Porcelain Health Manufacturing industry in Hamadan. Assessment of lifting tasks by NIOSH lifting equation and determining the prevalence of musculoskeletal disorders by Nordic questionnaire was conducted. Then, construction steps and determination of the effectiveness of ergonomic design was conducted.
Results: The results showed that the most frequent musculoskeletal disorders related to back. Results of the lifting index (LI) showed that the risk of lifting load in before intervention is high (greater than 3). This value after the conducting of ergonomic intervention (load-carrying cart) decreased to moderate level (between 1 to 3). The relationship of risk average amount before and after interventions were significant (p<0.001).
Conclusion: Load-carrying cart designed with shelves capable of moving vertically up and down has considerable role in safe making of lifting tasks and probability of reduce the prevalence of musculoskeletal disorders and lumbar injuries will bring in the near future.
Behrooz Karimi, Mohammad Sadegh Rajaei, Maryam Habibi, Mehri Esvand, Mehdi Abdollahy,
Volume 16, Issue 9 (12-2013)
Abstract
Background: Naphthalene is a polyaromatic hydrocarbon (PAHs) present in many water sediments. This study evaluated the performance of UV/H2O2 reaction to decompose naphthalene in the aqueous solution.
Materials and Methods: It was an experimental-laboratory study. A one liter cylindrical glass reactor was used for performing all degradation experiments. The radiation source was a low pressure mercury UV lamp emitting at 254 nm (30 W, UV-C) which was placed above a batch photoreactor for UV/H2O2 experiments and different concentrations of H2O2 (5, 10, 15, 20, 25 and 30 mg/L) were tested.
Results: In 15 mg/L naphthalene in UV/H2O2 system and reaction times 5, 10, 20, 30, 40, 50, 60, 100 and 120 minutes, 15, 28, 31 , 36, 42, 52, 56, 73 and 59.5% naphthalene removal efficiencies were observed and COD removal efficiencies in reaction times 5, 10, 20, 30, 40, 50, 60, 100 and 120 minutes, 22, 38, 45, 61.5, 67.5, 70, 80, 88.5 and 76 % were observed. When the initial pH values were 3, 4, 5, 6, 7,9, 10 and 12 the naphthalene removal efficiency was approximately 75.8, 63.4, 62, 58.5, 44.8, 35.8 and 30%, respectively, with UV/H2O2 system.
Conclusion: The experimental results of this study suggested that the dosages with 20 mg/L H2O2 at pH= 3 with 2.8 W/cm2 UV intensity (254 nm) provided the optimal operation conditions for the mineralization of naphthalene yielding a 73% mineralization efficiency after 100 minutes of reaction time.
Mohammad Javad Ghanadzadeh, Atena Bolhasani, Nader Akhavan Malayeri, Babak Eshrati, Mohsen Shamsi,
Volume 16, Issue 9 (12-2013)
Abstract
Background: Solid waste is one of the environmental pollution. Therefore the aim of this study was to survey of knowledge, attitude and practice of student and teachers about weast management for developing methods of educational in Arak city.
Materials and Methods: This is a cross sectional and analytical study that was carried out on 1739 student and 149 teacher in school of Arak city in 2012. sampling with cluster and data collection with questionnaire including knowledge, attitude, practice and appropriate resource of education for waste management. Finally data analyzed with statistical tests.
Results: The mean knowledge and attitude student was 4.1±1.9 (out of 8) and was 20.63±5.9 (out of 35) respectively. Based on most educational methods for weast management viewpoint of student book 441 student (29% ) but impact of internet very low interest 487 (32%) of student. Moreover the most educational methods based on level of education significant difference was observed (p=0.001).
Conclusion: Due to a level of knowledge and attitude of student and accsses to educational resourse and huge of weaste in school educational program planned via book, teacher and peer education for student recommended.
Zahra Fazeli, Mahbobe Najafian Zade, Babak Eshtati, Amir Almasi Hashiani,
Volume 16, Issue 11 (2-2014)
Abstract
Background: The prevalence and incidence of cancer in different parts of the world have different patterns. To recognize the frequency of malignancies in different social groups according to climatic conditions is considered as the primary component of prevention programs at different levels. This study was conducted to investigate the epidemiology, survival rates and geographical epidemiology of breast cancer in Markazi province.
Materials and Methods: In this epidemiological study, needed data were obtained from cancer registration program and death registration data. The data were analyzed by using SPSS software version 16 and Winpepi and significant level was 0.05. And to draw a map to show the breast cancer incidence rate in Markazi district, Arc view software was used.
Results: Out of the 400 cases recorded during the 5-year, 8.5% died due to breast cancer. 5-year survival rate was 87% and there was a significant correlation between survival rate and age. Most records were related to the age group 49-40 years and the highest incidence rate was in Arak. The trends of incidence rate was not significant.
Conclusion: The results showed that 5-year breast cancer survival rate is more than some other places which could be due to new and improved methods of treatment and methods of screening and early detection of disease. Other aspects of the epidemiology of the disease is similar to other parts of Iran.
Reza Ghafari, Mohammad Rafiei, Mohammad Reza Taheri Nejad,
Volume 16, Issue 11 (2-2014)
Abstract
Background: Today, the self-assessed health status is a standard part of epidemiologic and community based studies. The aim of this study is to assess and evaluate the health related quality of life in Qom city.
Materials and Methods: In this descriptive analytical study, population of 340 people over 18 years of Qom city entered the study by filling the questionnaires. A two-part questionnaire was used to collect data which the first part was related to demographic data including age, sex, marital status, education, occupation and place of residence. The second version of the SF-36 questionnaire was used to assess the quality of life.
Results: Generally, considering the all aspects of quality of life in this study, the mean (±SD) of scores was 67.69±14.78. This average was equal to 67.28±15.91 in men and 67.97±14.03 in women which showed a significant difference between them (p =0.030).
Conclusion: In this study the scores of women and single subjects were higher than other people. By the Persian version of 2nd version of SF-36 questionnaire, the quality of life people in different situations might be realized and impact of different demographic factors on quality of life could be measured.
Mohammad Reza Massoudinejad, Ashraf Mazaheri Tehrani, Farshid Ghanbari, Simindokht Mirshafian,
Volume 17, Issue 3 (6-2014)
Abstract
Background: The conventional methods of water disinfection are chemical process, ozonation, UV radiation, membrane processes and etc. In recent years, electrolysis method has been considered that is a green process with high efficiency and not by-products. The aim of study is evaluation of efficiency of the electrolysis process with continuous flow in the disinfection of water contaminated with fecal coliform.
Materials and Methods: This study is a Descriptive - analytical study. The samples are prepared in three groups by adding domestic wastewater, manure and E.Coli colonies to distilled water. The prepared samples were introduced to continuous electrochemical reactor. The removal efficiency of electrolysis process was investigated in different conditions which include electrode material (copper and graphite compressed), reaction time (40, 50, 60 and 70 minutes), voltage 48V, distance of electrode 5 cm and the initial pH 7.
Results: The results indicate that removal efficiency depends on source of pollutant, reaction time, and type of electrode. Also the optimal efficiency for E.Coli colonies achieved in electrolysis instrument was as follows: electrode material = copper electrode, distance of electrode=5cm, applied voltage= 48V and reaction time=70 minute. Under these conditions removal efficiency was obtained 99%. No significant changes in pH, TDS and EC in different times and coliform bacteria were not created by changing the source.
Conclusion: According to the results of this study, using the electrolysis process with continuous flow, as a convenient method with high performance and environmentally, suggest for the disin fecting the water contaminated with fecal Coliform.
Razie Rajabi, Akram Sharifi, Mohsen Shamsi, Amir Almasi Hashyani, Somayeh Dejam,
Volume 17, Issue 5 (8-2014)
Abstract
Background: Planning of educational programs to inform the people about the prevention of diseases such as cancers is necessary. This study was conducted to determine the effect of educational interference based on HBM on practices of women about gastric cancer.
Materials and Methods: In this semi-experimental study, 88 women participated from Arak. The subject were randomly divided in two groups, experimental group and control group (each group includes 44 women). Inclusion criteria were absence of cancer, Iranian nationality, age over 18 years, living in the city. Data collected with a questionnaire based on HBM and performance checklist about colorectal cancer prevention was used in order to evaluate the effectiveness of the educational program. Intervention was done in 1 month consist of 3 session each session 45 minutes. Three months later data were recollected and analyzed.
Results: In this study, the mean age in case and control group was 38.3±9.6 and 36.3±11.1 years respectively, with no significant differences (p=0.381). Average scores of knowledge and practice in experimental was 72.8±13.06 and 30.81±6.2 respectively group before the intervention, which was 88.05±12.2 and 65.3±8.9 respectively after the intervention (p<0.05). Moreover before of intervention susceptibility, severity and percieved benefit about practice of mothers was moderate but after intervention the entire items between experimental and control groups was significantly different (p<0.05).
Conclusion: Finding of this research confirms the effect of Health Belief Model on prevention from gastrointestinal cancer in women of Arak.
Reza Dehghanzadeh, Navid Safavy, Seyed Jamal Ghaem Maghami Hezaveh, Mojtaba Pourakbar, Shahram Nazari,
Volume 17, Issue 6 (9-2014)
Abstract
Background: Drugs residual discharge into the environment through municipal and hospital wastewaters is one of the emergent environmental problems. Imipenem as a professional hospital antibiotic is widely used against gram- positive and negative bacteria and with entrance to the aquatic environments could prompt a lot of risks such as bacteria resistance, allergies, spoiling alga and daphnia and interrupting in wastewater treatment processes. Therefore there is a command to develop a method for extraction and determination of Imipenem from hospital sewage.
Materials and Methods: Solid phase extraction (SPE) was used to extract Imipenem from samples. Recovery percentage calculated at different pH of 3 and 7. The extracted samples analyzed by High Performance Liquid Chromatography (HPLC) equipped with UV detector. HPLC operated using borate buffer/methanol as mobile phase at flow rate of 0.7 ml/min, column temperature of 20 °C, and UV wavelength of 280-300 nm.
Results: Maximum recovery percentage was obtained 68% at pH=7. The best condition for HPLC was 80:20 ratio of borate buffer/methanol with pH=7.5 and at UV wavelength of 300 nm. Linearity calculated 0.9829, primary and intermediate precision both were more than 95%. Limit of detection (LOD) and limit of quantification (LOQ) were 3 and 10 µg/l respectively.
Conclusion: The method could simply and with significant reliability be applied to extract and determinate Imipenem in complex hospital wastewater matrixes.
Hassan Izanloo, Mohammad Ahmadi Jebelli, Shahram Nazari, Navid Safavi, Hamid Reza Tashayoe, Gharib Majidi, Mohammad Khazaei, Vahid Vaziri Rad, Behnam Vakili, Hussein Aghababaei,
Volume 17, Issue 9 (12-2014)
Abstract
Background: This study aimed to examine the antibacterial effect of Polyamidoamine-G4 dendrimer on Escherichia coli, Enterobacter cloacae, Bacillus subtilis and Staphylococcus aureus.
Materials and Methods: In this experimental study, the antibacterial effects of Polyamidoamine-G4 dendrimer were studied by disc diffusion and micro-dilution method. Different concentrations of Polyamidoamine-G4 inoculated onto blank disks and were placed in Mueller-Hinton agar media. Zone of inhibition was investigated by bacterial inoculation according to the McFarland standard 0.5. Minimum inhibitory concentration and minimum bactericidal concentration of Polyamidoamine-G4 dendrimer were determined by micro-dilution method in nutrient broth culture.
Results: Zone of inhibition in concentration 500 &mug/ml of Polyamidoamine-G4 dendrimers for Escherichia coli, Enterobacter cloacae, Bacillus subtilis and Staphylococcus aureus were 14, 0, 35 and 29mm, respectively. Concerning the Zone of inhibition in gram negative bacteria with gram positive ones was p<0.05 and had significant difference. The minimum inhibitory concentration of Polyamidoamine-G4 dendrimer for Escherichia coli, Bacillus subtilis and Staphylococcus aureus were 1250, 2.5, and 1 &mug/ml, respectively. The minimum bactericidal concentration of Polyamidoamine-G4 dendrimer belonged to Escherichia coli, Bacillus subtilis and Staphylococcus aureus were 2500, 5 and 5 &mug/ml, respectively. Polyamidoamine-G4 dendrimer had not bacteriostatic and bactericidal effects on Enterobacter cloacae.
Conclusion: According to the results, Polyamidoamine-G4 dendrimer can eliminate Escherichia coli, Staphylococcus aureus and Bacillus subtilis effectively. It is suggested in the rest of this study that the probable toxicity of nanostructured compounds examined in drinking water and, economic studies is done for synthesis and their applications in case of prevention of using.
Saeid Razi, Hamid Salehiniya, Mehri Fathali Loy Dizaji,
Volume 18, Issue 2 (5-2015)
Abstract
Background: Cancer is one of the most common causes of deaths in the world. Cancer incidence and prevalence is increasing in the world. There is no clear trend is available on incidence of these cancers in Iran, therefore, this study aimed to determine the incidence of 10 common cancers among Iranian women from 2003 to 2009.
Materials and Methods: A cross-sectional study was conducted by analyzing existing data. Data from a national registry of cancer cases were received. Data included the records from the cancer registry system in Iranian women during 2003 to 2009. The incidence rates were then standardized using direct method. We used Cochrane Armitage Test for linear trend by Winpepi software to determine the variation in the incidence of cancers.
Results: The results show that the proportion of all cancers is rising in women as compared to all population. Breast, skin, colorectal, gastric, esophageal, thyroid, leukemia, ovary, brain and uterus were the most common cancer among Iranian women. During the years of the survey, these cancers are significantly increased.
Conclusion: The results of this study showed that the incidence of cancer in women is increased. screening programs can be useful in reducing the cancers.
