Esmaeel Moshiri,
Volume 4, Issue 3 (10-2001)
Abstract
Introduction: Thiopental is a short acting drug from barbiturates group, that is a favorable standard anesthetic for induction anesthesia because of pharmacologic effects. The goal of this study was to determine the incidence of thrombophlebitis with thiopental 2.5% and 5%.
Material and Method: Three hundred patients in ASA class I and II that referred to one of the college for elective surgery and was admitted 3 days after operative and was allocated in equal 2 groups (n=150) randomly. One group received thiopental 2.5% 4 mg/kg and the other group received thiopental 5% n 4mg/kg from one of the Veins of dorsum of hand.
Results: The incidence of phlebitis in this study was 1.33% (2 case from 150 case) in first group and 2% (3 case from 150) in second group. In both groups phlebitis was occurred in first 24 operative period and 2nd days no patient had not phlebitis in infusion site.
Conclusion: Thrombosis was not observed in patients in both groups. Incidence of phlebitis with thiopental 5% was greater than thiopental 2.5%.
