Showing 31 results for Mehri
Sahar Mehrabi, Maryam Shokrpoor, Mehri Jamilian, Hamidreza Sakhi,
Volume 18, Issue 7 (10-2015)
Abstract
Background: Episiotomy is one of the most common gynecologic surgery that was done in the second stage of labor, in order to facilitate the delivery. Cutting this area is associated with pain and discomfort. Healing causes pain relief and returning to daily activities became faster. Considering that the high rates of episiotomy infection, we decided to examine the effect of topical cream, saffron 20%, on women who had undergone episiotomy.
Materials and Methods: This randomized, double-blind clinical trial study was performed on 60 primiparous women in 2013-2014 who underwent vaginal delivery and episiotomy at in Taleghani Hospital of Arak. Intervention group recieved 20% topical cream containing saffron extract three times daily for 2 weeks and the control group received a placebo cream. Wound status and its healing were investigated in the first, seventh and fourteenth postpartum.
Results: There was a significant difference between both groups with healing of episiotomy location in seventh(p=0.54) and fourteenth(p=0.003) days and the continuity process of the wound edges in the first (p=0.015), seventh(p=0.013) and fourteenth(p=0.001) days. there was no statistically significant difference about the opening the wound in the first day(p=0.492), There was a statistically significant difference between the two groups in seventh(p=0.001) and fourteenth(p=0.026) days.
Conclusion: This study showed that saffron extract cream 20% can be effective for episiotomy wound healing and wound edges continuity.
Mehri Jamilian, Masoomeh Heydari,
Volume 18, Issue 9 (12-2015)
Abstract
Background: Missed abortion refers to pregnancy products remain dead with age less than 20 weeks in the womb for several weeks. This study was designed to evaluate the efficacy of castor oil on cervical ripening in the treatment of abortion.
Materials and Methods: This triple blind clinical trial was done on 72 women with missed abortion who were divided into two groups of 36 patients based on odd or even numberd of cases. The case groups received 800 mg vaginal misoprostol and 60 ml castor oil mixed with fruit juice and control groups received 800 mg vaginal misoprostol and 60 ml placebo with fruit juice, respectively. In both groups, if needed, 3 doses of vaginal suppository 800 mg were repeated with at least 24 hours. After the disposal of pregnancy products, sonography and curettage were performed if necessary.
Results: During the intervening period, the time of the opening of the cervix in the intervention group was shorter than control group and there was a statistically significant difference (p=0.032). Also, the control group required a higher frequency of administration of misoprostol than intervention group and the difference was statistically significant (p = 0.037).
Conclusion: It seems that the castor oil can be effective on cervical ripening for treatment of abortion.
Hamid Reza Jamilian, Mostafa Nokani, Mohammad Reza Khansari, Mahamood Ajloo, Farzaneh Doroodgar, Mehri Jamilian,
Volume 19, Issue 3 (6-2016)
Abstract
Background: Adoption has a significant role for strengthening families without children and also resolution of psychological confilicts of unsupervised children. The goal of this study is to assess the psychological status of adoption applicant couples.
Materials and Methods: This is a descriptive- analytic study that is done with cooperation of welfare organization and Arak University of Medical Sciences in 2014. All adoption applicant couples referred to welfare organization for 1 year participated in the study. Data were gathered by using demographic questionnaire and MMPI-II. Data were showed by descriptive statistic and were analyzed by using mean, average and covariance analysis indices.
Results: Mean and standard deviation of all clinical scales and reliability of MMPI-II in all samples and also different subgroups of statistical population were under 65. All applicants had good mental health and psychologically were eligible for adoption. A group of applicants have pretended themselves better than what they are because of the fear of rejection that led to significant difference in k scale(p=0.019).
Conclusion: According to the findings of this study, applicants had good mental health and didn’t have any psychopathologic damage, but sometimes they have pretended themselves better than what they are. Investigation of other diagnostic tools in future studies is recommended.
Mehri Jamilian, Somayeh Bakhshayeshy,
Volume 19, Issue 6 (9-2016)
Abstract
Background: Few studies have examined the effects of calcium plus vitamin D supplementation on metabolic profiles in overweight women with polycystic ovary syndrome (PCOS).This study was conducted to determine the effects of calcium plus vitamin D supplementation on metabolic profiles among overweight women with PCOS.
Materials and Methods: This randomized double-blind placebo-controlled clinical trial was conducted among 104 overweight and obess women with PCOS. Participants were randomly assigned into four groups to receive: 1) 1000 mg/d calcium+ vitamin D placebo; 2) 50000 IU/weeks vitamin D; 3) 1000 mg calcium/d and 4) calcium placebo + vitamin D placebo for 8 weeks. Fasting blood samples were taken at baseline and after 8 weeks intervention to measure metabolic profiles.
Results: After administrating calcium plus vitamin D supplementation, a significant decrease was observed in serum insulin (-3.3±11.4 vs.-1.1±8.5, -1.4±3.0 and +3.1±6.1 µIU/ml, p=0.03), insulin resistance (-0.7±2.4 vs.-0.3±2.5, -0.2±0.6 and +0.8±1.9, p=0.04), malondialdehyde (-0.6±0.3 vs.-0.1±0.2, -0.5±0.2 and +0.6±0.4 µmol/L, p=0.009) and a significant rise was seen in total antioxidant capacity (+35.2±21.7 vs.+22.5±37.7, +21.1±34.1 and -153.8±65.2 mmol/L, p=0.006) and glutathione (+216.0±79.3 vs.-47.5±60.2, +3.9±31.3 and -160.8±82.9 µmol/L, p=0.001) compared with vitamin D, calcium and placebo groups.
Conclusion: In conclusion, calcium plus vitamin D supplementation for eight weeks among women with PCOS had beneficial effects on metabolic profiles.
Mehri Jamilian, Zeinab Zolfi,
Volume 19, Issue 8 (11-2016)
Abstract
Abstract
Background: We are aware of no study evaluating the effects of zinc supplementation on metabolic profiles of patients with polycystic ovary syndrome (PCOS). This study was conducted to evaluate the effects of zinc supplementation on glucose homeostasis parameters in PCOS women.
Materials and Methods: This randomized, double-blind, placebo-controlled trial was conducted among 52 women diagnosed with PCOS and aged 18-40 years old. Participants were randomly divided into two groups to receive 220 mg zinc sulfate (containing 50 mg zinc) supplements (n=26) or placebo (n=26) per day for 8 weeks. Fasting blood samples were taken at baseline and after 8 weeks of intervention to quantify glucose and insulin.
Results: After 8 weeks of intervention, zinc-supplemented patients had reduced fasting plasma glucose (FPG) (-4.3±9.6 vs. +0.5±6.0 mg/dL, p=0.03), serum insulin (-3.0 ± 2.9 vs. + 1.5 ± 8.4 µIU/ml, p=0.01), serum triglycerides levels (-15.6±40.3 vs. +14.5±25.3 mg/dL, p=0.002) and a significant increase in insulin sensitivity (+0.02±0.02 vs. -0.004±0.05, p=0.03) compared with the placebo.
Conclusion: Taken together, 220 mg zinc sulfate supplementation per day for 8 weeks among PCOS women had beneficial effects on metabolic profiles.
Mehri Jamilian, Roghayeh Afshar,
Volume 19, Issue 12 (3-2017)
Abstract
Abstract
Background: The efficacy of evening primrose oil has been reported in metabolic syndrome and other diseases.The role of vitamin D has been proposed in the risk reducing of chronic diseases such as obesity, metabolic syndrome and diabetes too. We are aware of no study that examined the effects of evening primrose oil and vitamin D supplementation on metabolic profiles in gestational diabetes (GDM). This study was designed to assess the effects of evening primrose oil and vitamin D supplementation on metabolic profiles among pregnant women with GDM.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was performed among 60 women with GDM. Subjects were randomly assigned to receive either evening primrose oil and vitamin D supplements (n=30) or placebo (n=30) for 6 weeks. Fasting blood samples were taken at study baseline and after 6 weeks of intervention to quantify biochemical variables.
Results: Evening primrose oil and vitamin D supplementation led to a significant decrease in serum high sensitivity-C reactive protein (hs-CRP ) levels (change from baseline: -1.9±4.0 vs. +0.6±2.6 µg/mL, p=0.006) and MDA (-0.8±2.1 vs. +0.6±1.5 µmol/L,p=0.005) compared with placebo. Furthermore, a significant increase in plasma NO (+2.5±3.8 vs. -1.9±8.1 µmol/L, p=0.009) and TAC levels (+84.4±174.8 vs. -36.4±143.1 mmol/L, p=0.005) was seen after evening primrose oil and vitamin D supplementation compared with placebo.
Conclusion: Evening primrose oil and vitamin D supplementation in GDM women had beneficial effects on metabolic profiles.
Mehri Jamilian, Reyhaneh Sahebkashaf,
Volume 20, Issue 1 (4-2017)
Abstract
Abstract
Background: We are aware of no study examining the effects of Soy supplementation on patients with polycystic ovary syndrome (PCOS).This study was conducted to evaluate the effects of Soy supplementation on metabolic profiles in women with PCOS.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was conducted among 70 women diagnosed with PCOS. Participants were randomly divided into two groups to receive 50 mg Soy isoflavone supplements (n=35) or placebo (n=35) for 12 weeks. Fasting blood samples were taken at baseline and after a 12-week intervention to quantify related factors.
Results: Intervention group, subjects who received Soy supplements had significantly decreased total serum testosterone levels (-0.2±0.4 vs. +0.1±0.3 ng/mL, p=0.01) compared with the placebo. In addition, a significant rise in plasma glutathione (+96.0±102.2 vs. +22.7±157.8 µmol/L, p=0.04) and a significant decrease in malondialdhyde levels (-0.7±0.8 vs. +0.8±2.3, p=0.001) was observed following the consumption of Soy supplements compared with the placebo.
Conclusion: According to this study, Soy supplementation among PCOS women had beneficial effects on metabolic profiles.
Mehri Jamilian, Jamilian Somayeh Jamshidi,
Volume 20, Issue 10 (1-2018)
Abstract
Abstract
Background: Selenium supplement has multiple important effects, including anti-inflammatory effect. The aim of this study was to assess the effects of selenium supplement on gene expression of inflammatory cytokines and vascular endothelial growth factor in gestational diabetes.
Materials and Methods: This randomized double blind placebo control trial was performed on 40 patients suffering from GDM aged 18–40 years old. Participants were randomly divided into interventional group receiving 200mg/day selenium supplements (n=20) and control group receiving placebo (n=20) for 6 weeks. Primary outcome was gene expression of inflammatory cytokines and VEGF which were assessed in lymphocyte of GDM patients by RT-PCR method.
Results: After 6 weeks intervention, in comparison with the control group, interventional group showed down regulation of gene expression of tumor necrosis factor alpha (TNF–α) (p=0.02) and transforming growth factor beta (TGF–β) (p=0.01) and up-regulation of gene expression of vascular endothelial (VEGF) (p = 0.03) in lymphocytes of GDM. There was not any significant change following intervention with selenium regarding gene expression of interleukin IL-1 β and IL-8 in lymphocytes of GDM patients.
Conclusion: 6 weeks supplementation with selenium in patients with GDM can cause down regulated gene expression of TNF-α and TGF–β, and up regulated gene expression of VEGF. Selenium supplement had not any effect on gene expression of IL-1 β and IL-8.
Mehri Jamilian, Nazanin Ravanbakhsh,
Volume 21, Issue 5 (10-2018)
Abstract
Background and Aim: We are aware of no study that examined the effects of vitamin E plus omega-3 fatty acid supplementation on inflammatory and oxidative stress biomarkers in pregnant women with gestational diabetes (GDM). This study aimed to evaluate the effects of vitamin E plus omega-3 supplementation on insulin metabolism and inflammatory and oxidative stress biomarkers in pregnant women with gestational diabetes.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was performed on 60 women with GDM. Subjects were randomly assigned to receive either 400 IU vitamin E plus 1000 mg omega-3 fatty acid supplements (n=30) or placebo (n=30) for 6 weeks. Fasting blood samples were taken at study baseline and after 6 weeks of intervention to quantify biochemical variables.
Findings: Vitamin E plus omega-3 fatty acid supplementation led to a significant rise in plasma total antioxidant capacity (+187.5±224.9 vs. -32.5±136.1 mmol/L, p<0.001) and a significant decrease in MDA levels (-0.1±0.9 vs. +0.6±1.4 µmol/L, p=0.04) compared with placebo. Furthermore, a significant increase in plasma NO levels (+5.0±7.7 vs. -12.0±28.0 µmol/L, p=0.002) was seen after vitamin E plus omega-3 fatty acid supplementation compared with the placebo.
Conclusion: Vitamin E plus omega-3 fatty acid supplementation in GDM women had beneficial effects on biomarkers of inflammation and oxidative stress.
Somaye Delavar, Niloofar Shadmehri, Hamid Dalvand,
Volume 22, Issue 1 (4-2019)
Abstract
Background and Aim: Children with cerebral palsy (CP) may have musculoskeletal disorder due to inappropriate position during sleep. The aim of this study was to design the equipment for sleep positioning of children with CP.
Materials and Methods: This research was a designing device study for sleep positioning of children with CP. The design was carried out in three stages: needs assessment, develop an idea and final design. Seventeen children with CP aged 2-12 year olds at the levels of III to V Gross Motor Function Classification System Expanded and Revised (GMFCSE&R) were recruited from Tehran and Karaj rehabilitation clinics by a convenience sampling strategy. For data collection, some demographic questionnaire and GMFCS E&R were used.
Ethical Considerations: This study was approved in Research Ethics Committee of Faculty of Applied Arts at Tehran University of Art with the code IR. ART U.REC.1394.118.
Findings: In the process of needs assessment, a researcher made questionnaire and pictures of sleep positioning children with CP when they were sleeping were used. In developing an idea stage, the free and creative ideas under the name of black box, as well as, Etudes at the transparency stage were presented as the combination of creative ideas. In the final design stage, by using superior materials, positioning and packaging, we achieved a superior design.
Conclusion: The proposed plan is designed as an interventional tool based on the need of Iranian children with CP and there is no similar national or international device available. The final design of the sleeping equipment includes a set of mattresses and a variety of modular styling devices based on a family centered approach, so that, allow parents to active engagement during sleep and rest of their children and can help the children to assume the proper positions.
Mohammad Sadegh Maschi, Sheida Sodagar, Farhad Jomehri, Marjan Hosseinzadeh Taghvai, Mojgan Forootan,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: Patients with the symptoms of gastrointestinal diseases and ulcers constitute a large number of patients referring to general and internal clinics. Furthermore, preliminary studies on gastric ulcers highlighted the role of psychological factors in the development of a susceptible gastric ulcer. The current study aimed to determine the effects of Cognitive-Behavioral Therapy (CBT) on pain intensity and stress coping styles in patients with gastric ulcers.
Methods & Materials: This was an experimental study with a pretest-posttest-follow-up and a control group design. The statistical population included all patients with a gastric ulcer who were referred to public health centers in Tehran City, Iran, in the winter of 2018. Among the volunteers participating in the study, 30 patients with gastric ulcers were selected by the convenience sampling method. Next, they were randomly assigned to the experimental and control groups (n=15/group). Measurement tools included the McGill Pain Questionnaire (MPQ) and the Coping Inventory for Stressful Situations (CISS; Endler & Parker, 1990). The experimental group subjects participated in eight 90-minute sessions of CBT. However, the controls received no psychological treatment in this period. For data analysis, repeated-measures Analysis of Variance (ANOVA) and post-hoc tests were applied.
Ethical Considerations: This study was approved by the Research Ethics Committee of the Islamic Azad University, Karaj Branch (Code: IR.IAU.K.REC.1397.85).
Results: The present research results signified that CBT improved problem-oriented coping styles (P<0.01) and decreased emotion-focused coping styles (P<0.01) and avoidance (P<0.01) in the test group. Besides, the mean scores of pain intensity decreased in the experimental group, compared to the controls (P<0.01).
Conclusion: The provided CBT was effective on pain intensity and stress coping styles in patients with gastric ulcers.
