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Showing 69 results for Mojtaba

Mojtaba Khansooz, Bahram Abedi, Mehdi Moradi, Abbas Mehranpour,
Volume 19, Issue 12 (3-2017)
Abstract

Abstract

Background: The aim of this study was to investigate the acute effect of supplementation Jadvar on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzymes after exhaustive incremental exercise in men's handball.

Materials and Methods: In this semi-experimental double blinded study 12 handball players with at least 2 years record in league (with average age=21.42, height=186cm, weight=83.25, and body mass index=24.09kg/m2) divided into 2 groups (n=6) accidentally. Both groups performed maximum Bruce protocol until exhausting level. Before (fasting) and after performing protocol ,blood samples were taken from middle forearm vein and transferred to lab then supplementation group consumed three 500 mg jadvar capsules and control group consumed three 500 mg maltodextrin  for 7 days daily. 24 hours after eating last capsule ,they performed maximum Bruce protocol up to exhausting level and the samples were collected like primary protocol blood samples before (fasting)and after performing protocol and were transferred to the laboratory.

Results: The results of dependent and independent t-test showed that consuming jadvar supplements for 7days did not have significant effect on aspartate aminotransferase(AST) and alanine aminotransferase(ALT)(p≥0.05).But alanine aminotransferase in supplementation group (16.83 mg.dl-1) decreased in comparison to placebo group (20.5 mg.dl-1). Also, aspartate aminotransferase was increased from 28 mg.dl-1 to 35.17 mg.dl-1 , but neither decrease nor increase was not meaningful (p≥0.05).

Conclusion: It seems that acute consuming of jadvar supplement and one session incremental exercise does not have meaningful effect on AST and ALT in man handball players.


Mojtaba Rahimi Varposhti, Darioush Moradi Farsani, Babak Ali Kiaei, Behzad Nazem Roaya, Seyed Hosein Moosavi,
Volume 20, Issue 3 (6-2017)
Abstract

Abstract

Background: The aim of this study is to evaluate the impact of preemptive adding topical Ketorolac to Tetracaine drop on pain intensity and hemodynamic parameters during and after cataract surgery.

Materials and Methods: Eighty patients scheduled for elective cataract surgery under sedation and topical anesthesia, were randomly allocated to two equal groups: group T received Tetracaine 0.5%, and group TK received Tetracaine with ketorolac eye drops. One drop of each ophthalmic drug was applied every 10 minutes from 30 minutes before surgery. Pain intensity and hemodynamic parameters were assessed just before starting the operation and 5, 10, 15and 20 minutes during the operation, and then 0, 5, 10, 15 and 20 minutes after arrival of the patient to the recovery room.

Results: Mean pain intensity was significantly lower in TK group (1 ± 0.128) compared with T group (2 ± 1.54) during the surgery (p = 0.003), but there was no significant difference between the two groups in this regard during the recovery time (p =0.157). The number of patients requiring additional analgesic was not significantly different between the groups. There was no significant difference between the two groups regarding hemodynamic parameters except at 20th minutes and 15th and 20th minutes (heart rate and respiratory rate) after arrival to the recovery room.

Conclusion: Preemptive adding topical Ketorolac to Tetracaine drop is more effective than Tetracaine alone to reduce pain during cataract surgery.


Mohabbat Jamhiri, Zeinab Hafizibarjin, Mojtaba Ghobadi, Ali Moradi, Fatemeh Safari,
Volume 20, Issue 4 (7-2017)
Abstract

Abstract

Background: Oxidative stress plays an important role in the pathogenesis of hypertension- induced cardiac hypertrophy. Plants are a rich source of antioxidant compounds. Thymol is a natural monoterpen phenol which is plentiful in some plants and shows many biological effects. The aim of the present study was to assess the effects of thymol on activity of antioxidant enzyme catalase, malondialdehyde (MDA) level and the activity of the inhibition of free radical DPPH (2,2-Diphenyl-1-picryl-hydrazyl), following left ventricular hypertrophy in rats.

Materials and Methods: In this experimental study, rats were divided into hypertrophied group without any treatment (H group) and rats pretreated with 25 and 50 mg/kg/day of thymol (Thy25+H and Thy50+H groups, respectively). Intact animals were served as control (Ctl). Animal model of left ventricular hypertrophy was induced by abdominal aortic banding. Serum catalase (CAT) activity, malondialdehyde (MDA) level and the activity of inhibition of free radicals DPPH were determined by the biochemical methods.

Results: In Thy25+H and Thy50+H groups, the CAT activity was increased significantly in serum (p<0.01, vs. Ctl). Also, serum level of MDA was decreased significantly compared to the group H in Thy25+H and Thy50+H groups (p<0.05 and p<0.001, respectively). The effect of inhibiting DPPH free radicals was increased significantly in Thy25+H and Thy50+H groups compared to the group H (p<0.001 and p<0.05, respectively).

Conclusion: The findings of this study suggest that thymol as an antioxidant causes cardioprotective effects and as well as prevents left ventricular hypertrophy via augmentation of serum antioxidant capacity.


Mojtaba Asgari, Masoumeh Asle-Rousta, Mohammad Sofiabadi,
Volume 20, Issue 5 (8-2017)
Abstract

Abstract

Background: Diabetes is the most common endocrine disorder that leads to hyperglycemia and hyperlipidemia. Royal jelly is as a bee-collected natural product has diverse biological properties and that is rich in natural antioxidants. The aim of this study was to investigate the effects of royal jelly on serum glucose and lipids profile in streptozotocin induced type 1 diabetic rats.

Materials and Methods: In this experimental study, 40male Wistar rats were divided into 5 groups(8 in each): control, diabetic rats, Glibenclamide, and two groups of royal jelly- treated diabetic. Diabetes was induced in the rats by injection of streptozotocin (60 mg/kg b.w) intraperitoneally. The royal jelly was gavaged at doses of 100 and 200 mg/kg after streptozotocin injection for30 days. At the end of this period, levels of glucose, cholesterol, triglyceride, LDL and HDL in serum were measured.

Results: Royal jelly and Glibenclamide significantly decreased the levels of glucose, cholesterol, triglyceride and LDL in diabetic rats (p<0.01). In addition, significant increase (p<0.01) in HDL level was observed in royal jelly-treating rats in comparison to the diabetic rats.

Conclusion: The results indicated that royal jelly may be used effectively in controlling and attenuating the complications of diabetes. The hypoglycemic and hypolipidemic effects of royal jelly may be due to the presence of antioxidants.


Mahdi Jafarzadeh, Mojtaba Salouti, Rasoul Shokri,
Volume 20, Issue 6 (9-2017)
Abstract

Abstract
Background: Candida glabrata is the fourth most common cause of blood infection in America and, due to its resistance to amphotericin B, we have to look for new therapies. The aim of this study was to evaluate the antifungal properties of silver nanoparticles, copper and combine them together with amphotericin B in order to produce an effective drug.
Materials and Methods: Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for nano silver copper and combining them together and amphotericin B was conducted by macro dilution. By intraperitoneal injection, anti-fungal effect of nano silver, copper and combining them together and amphotericin B was evaluated in a mouse model.
Results: The amounts of MIC and MFC for silver nanoparticles, copper nanoparticles and their combination were 31 and 62.50 ppm, 31 and 62.50 ppm ,and 31and 15.50 ppm, respectively. The amounts of MIC and MFC for the combination of silver nanoparticles and amphotericin B were 8 and 15.5 ppm, also, 15.5 and 31 ppm for the combination of copper nanoparticles and amphotericin B. Mouse model study confirmed the effect of silver nanoparticles, copper nanoparticles and combining them together and amphotericin B against Candida glabrata. The combination of silver and copper nanoparticles had maximum effect and the combination of silver and copper nanoparticles with amphotericin B had minimum effect in animal model.
Conclusion: The combination of silver and copper nanoparticles has a better effect than other groups.

Mojtaba Rahimi Varposhti, Darioush Moradi Farsani, Kamran Montazeri, Fatemeh Tanha,
Volume 20, Issue 8 (11-2017)
Abstract

Background:
 
This study aimed to compare the effect of cold eye irrigation solution (BSS) and viscoelastic gel with their combination in room temperature on the dosage of sedative drugs which we use in Phacoemulsification cataract surgery.
 
Material and methods:
 
190 patients scheduled for cataract surgery under sedation were randomly divided into two equal groups. During surgery we used cold (4c) and warm (room temperature) BSS and viscoelastic gel in the first and second group respectively. For all patients we started sedation with Midazolam and Fentanyl and in case we needed additional drug we used Sodium Thiopental till we reached desired sedation level. Ramsay sedation scores (before, during and after surgery) and total sedative drug consumption   were evaluated   and compared between two groups and at the end of the surgery we checked the satisfaction score of patients and surgeon about the quality of sedation.
 
Results:
The average dosage of Midazolam wasn’t significantly different between the two groups, while the average dosage of Sodium Thiopental was significantly lower in Cold group. Also the average time of which we reached desired Ramsay sedation score and the level of Ramsay score were significantly different between the two groups.
 Conclusion:
Using cold BSS and viscoelastic gel in cataract surgery in comparison of their combination in room temperature will reduce the dosage of sedative drugs which we use during surgery and help us getting a more effective sedation and gaining both a satisfied patient and surgeon.
 
Esmaeil Soleimani, Shahin Azmoodeh, Mojtaba Habibi,
Volume 20, Issue 9 (12-2017)
Abstract

Abstract
Background: In present research, the structural equation modeling of the relationship between cognitive avoidance and rumination with clinical symptoms of OCD with mediating role of cognitive failure was studied.
Materials and Methods: In a descriptive correlational study, 220 patients with OCD were selected from Urmia psychological clinics and completed YBOCS, RRS, CAQ, and CFQ questionnaires. For data analysis, structural equation modeling (SEM) was used.
Results: The results showed that the modified final model is best fitted with present research data and cognitive avoidance, rumination, and cognitive failure paths with OCD and cognitive avoidance, and rumination paths with cognitive failure were significant. Also, indirect paths such as cognitive avoidance and rumination to OCD were significant.
Conclusion: According to the results of this study, it can be concluded that in addition to the direct relationship, cognitive failure can adjust the relationship between cognitive avoidance and rumination with OCD.

 

Darioush Moradi Farsani, Khosro Naghibi, Mojtaba Rahimi Varposhti, Bahador Malekipoor, Tahereh Fasihi,
Volume 20, Issue 9 (12-2017)
Abstract

Abstract
Background: Postoperative nausea and vomiting (PONV) is one of the most common complications in the patients undergoing strabismus surgery. The aim of current study was comparing supplemental 80% and 40% oxygen on reducing postoperative nausea and vomiting in the pediatrics undergoing strabismus surgery.
Materials and Methods: In this clinical trial study, 100 pediatric patients scheduled for strabismus surgery under general anesthesia were allocated randomly into two parallel supplemental 80% and 40% oxygen groups during surgery. PONV in patients was compared until 24hrs after operation.
Results: In the first 6hrs postoperatively, PONV in the supplemental 40% and 80% oxygen groups were 48.8% and 30.6% respectively, also were 20.8% and 12.2% in the 6 to 24hrs postoperatively. Therefore, there were no significant differences between both groups in regarding of PONV in 6hrs and 6 to 24hrs postoperatively (p values were 0.18 and 0.25, respectively).
Conclusion: According to our results, there is no any difference between 40% and 80% oxygen postoperatively in the pediatrics undergoing strabismus surgery.

 

Mina Ghasemi, Zeinab Khazaei Koohpar, Mojtaba Falahati,
Volume 21, Issue 3 (6-2018)
Abstract

Background and Aim: Prolonged ischemia in organs with high metabolic rates such as brain and heart is associated with deleterious effects. Therefore, nutritive distribution through angiogenesis after ischemia is necessary for repairing damaged region of tissue. In this study, the effects of iron oxide nanoparticles and magnetic field on angiogenesis after ischemia reperfusion (IR) in rat model have been investigated.
Materials and Methods: In this experimental study, fifty male rats aged between 6 -7 weeks at the 220-250gr weight were purchased from Tehran University. Animals were categorized in 5 groups including sham (ischemia reperfusion model), control, iron oxide nanoparticles-treated, magnetic field-exposed, and combination therapy with iron oxide nanoparticles and magnetic field-exposed groups. Angiogenesis was evaluated in hippocampus of 5 groups after 4 days by H&E staining method. The expression of Vegfa gene was studied in 5 groups by Q-RT- PCR.
Findings: Iron oxide nanoparticles as well as the magnetic field induced angiogenesis during 4 days in animals after IR (p<0.05), but their combination therapy did not show any significant difference compared to sham group during 4 days. Upregulation of Vegfa gene was observed in iron oxide nanoparticles treated group and the magnetic field exposed group significantly (p<0.05) relative to ischemia reperfusion (IR) model. But overexpression of Vegfa gene in combination therapy group was not significant relative to ischemia reperfusion (IR) group.
Conclusion: It seems that iron oxide nanoparticles and magnetic field can separately be two effective methods for angiogenesis after ischemia reperfusion (IR).

Mojtaba Habibi, Nikzad Ghanbari, Moloud Sivandian, Hanieh Mahdizadeh Hanjani,
Volume 21, Issue 5 (10-2018)
Abstract

Background and Aim: Present study was conducted to investigate the prediction of juvenile delinquency based on individual vulnerability and the risk opportunity in the family, peers, school and neighborhood in high schools in Tehran
Materials and Methods: This is a coss-sectional study. The statistical population of this study included all the female and male students of 20 districts of Tehran who were studying in high school during the academic year 2013-2014. The sample size of the study was 1847 individuals (946 (51.2%) girls and 901 (48.8%) boys). The sampling was performed in a multi-stage cluster method due to the extent of the population, and the participants of this study completed the socio-mental protective and risk factors and behaviors scale. Data were analyzed using multiple regression analysis, stepwise method, and SPSS-24 statistical software.
Findings: Results of present study showed that among predictor variables, risk opportunity/availability (B=0.67, t=13.28, p<0.001), vulnerability/family (B=0.37, t=8.57, p<0.001), and vulnerability/school (B=1.14, t=6.7, p<0.001) have significant prediction effect on adjusted index of adolescents’ delinquent behavior, also adolescent boys do more delinquent behavior than girls (t (1823) =4.82, p<0. 01).
Conclusion: This study showed that the individual vulnerability and risk opportunity in the family, peers, school and neighborhood predict delinquent behavior in adolescents. So, it is necessary to take preventive measures and interventions for this age group, risk factors should be considered at individual, school and family levels.

Leila Dehghan, Hamid Dalvand, Mojtaba Bayani, Alireza Shamsoddini,
Volume 22, Issue 2 (6-2019)
Abstract

Background and Aim: Feeding problems can limit the participation of children with cerebral palsy (CP) in the daily activities of life, especially feeding and eating. The aim of this study was to determine frequency of primary oral reflexes and oral motor dysfunction in children with CP.
Materials and Methods: This study was a descriptive-analytic and cross-sectional study that has been done on children with CP aged 2-15 years old. The participants were chosen by a convenience sampling from the rehabilitation clinics in the city of Arak in 2017. The presence of primary abnormal oral reflexes including Bite, Rooting, and Tongue Thrust was evaluated; and Oral motor assessment scale was used to evaluate oral motor function.Data were analyzed using statistical tests including chi-squared test.
Ethical Considerations: This study with research ethics code IR.ARAKMU.REC.1395.82 has been approved by research ethics committee at Arak university of medical sciences, Iran.
Findings: Based on the present results, the most subjects with primitive oral reflexes (bite, rooting, tongue thrust) were found at levels of IV and V Gross Motor Function Classification System Expanded &Revised(GMFCS E&R) and at level of III Manual Abilities Classification System and type of quadriplegia spastic. The highest frequency of passive in oral motor was observed in level of V and functional in oral motor in levels of I and II GMFCS E&R. Furthermore, there was significant difference between gross motor function and oral motor function.
Conclusion: The study results demonstrated a significant difference between GMFCS E&R levels and oral motor function. Therefore, it was suggested that particular attention should be paid to oral motor function in terms of evaluations of gross motor function.

Fatemeh Sadat Hashemi, Mojtaba Habibi , Sara Sepahvand, Ali Moghaddam Zadeh, Fahimeh Lavassani,
Volume 22, Issue 3 (8-2019)
Abstract

Background and Aim: The aim of this study was to present a conceptual model of spiritual well-being in prevention of substance abuse in adolescent.
Materials and Methods: The present study was done with a qualitative meta-synthesis with systematic review of the studies present in the foreign and Iranian journals about spiritual well-being and the role of them in prevention of substance abuse in adolescents. The population of this study consisted of non-interventional archive studies that were done during 1986 -2016 in Oxford Journal, Science Direct, Wiley Online Library, Taylor&Francis, ProQuest, Springer, Iranmedex, Irandoc, SID and Magiran. Keywords were including of spiritual well-being, spirituality, prevention of substance abuse and adolescents.
Ethical Considerations: This study with ethics code 8797/1129 has been approved by Farabi Campus of University of Tehran.
Findings: After reviewing and evaluating the quality of the research, eventually 73 papers and theses included 8 Persian articles, 65 English papers including 11 theses and 54 articles were found and dissertations and finally conceptual model based on fisher (1998) theory's, wree presented. On this ground, subcategory of spiritual well-being was consisted of three theme of relationship with others, relationship with self and relationship with God. Each of them consisted of two subtheme of psychological health (interpersonal and intimate) and psychological well-being(interpersonal and intimate).
Conclusion: The results showed that spiritual well-being influenced on multiple dimensions of adolescent psychological health and well-being and prevention of adolescent substance abuse from this way.

Ali Iranpoor, Mojtaba Bayani, Mohammad Arjomandzadegan, Afrooz Nakhostin,
Volume 22, Issue 4 (9-2019)
Abstract

Background and Aim Periodontal diseases are among the most prevalent inflammatory diseases caused by oral bacteria. Expansion of oral biofilm causes various diseases such as gingival inflammation and periodontitis. The Satureja plant has various species, all of which are aromatic. This plant is traditionally used for the treatment of some diseases. The present study was conducted to evaluate the effect of Satureja essential oil on periodontal pathogens.
Methods and Materials In this study, we evaluated four pathogens; Enterococcus faecalis, Streptococcus sanguinis, Eikenella corrodens, and Actinomyces viscosus. We also used the disk diffusion test and broth microdilution method to evaluate the antimicrobial effect of Satureja essential oil. Finally, we determined the minimum inhibitory concentration and minimum bactericidal concentration.
Ethical Considerations The Ethics Committee of Arak University of Medical Sciences approved this study (Code: IR.ARAKMU.REC.1397.67).
Results In concentration of 0.1 g/mL of Satureja plant, Actinomyces viscosus, Streptococcus sanguinis, Enterococcus faecalis, and Eikenella corrodens were found to be sensible to resistance. The Satureja essential oil had the highest effect on Eikenella corrodens. Results obtained from the biofilm test showed no biofilm in a concentration of 12.5 mg/mL and higher of Satureja plant.
Conclusion The Satureja plant was found to have an antibacterial and inhibitory effect on biofilm growth and formation in the oral cavity. 

Mina Mirnezami, Bahman Sadeghi, Sajid Ghadbighi, Farid Sahabi, Mojtaba Ahmadloo,
Volume 22, Issue 5 (11-2019)
Abstract

Background and Aim Male Androgenic Alopecia (MAA) is one of the most common causes of hair loss in men. Minoxidil solution is one of the most commonly used medications for MAA treatment; however, it has several cutaneous side effects including itching, scaling and erythema, which cause the discontinuation of its consumption.
Methods & Materials In this double-blind randomized clinical trial, 51 males with MAA were treated with 5% minoxidil solution and 7% chamomile extract. At the same time, 49 patients as controls were matched with this group and treated with 5% minoxidil solution alone. Both groups were treated and followed up for 6 months.
Ethical Considerations This study has received its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences (code: IR.ARAKMU.REC.1395.456) and is a registered clinical trial (Code: 2017042420258N41).
Results In both groups, the severity of itching and scaling gradually decreased. in the control group, erythema increased, while in the chamomile group, erythema also decreased. All three side effects of itching, scaling and erythema were lower in the group treated with chamomile extract and minoxidil solution than in the group used minoxidil solution alone.
Conclusion It seems that simultaneous administration of 7% chamomile extract and 5% minoxidil solution leads to a reduction in the severity and duration of cutaneous side effects caused by minoxidil solution use in treatment of MAA. It can increase the patient's compliance to the treatment and eventually the chance of MAA treatment.

Fatemeh Momeni, Afrooz Nakhostin, Mojtaba Bayani,
Volume 23, Issue 1 (April & May 2020)
Abstract

Background and Aim: Periostin acts as necessary protein in tissue development and has a key role in tooth-supporting tissues such as periodontal ligament. The effect of inflammation on reducing periostin level has been shown in some studies. The aim of this study was to compare the salivary and Gingival Crevicular Fluid (GCF) periostin levels in patients with chronic periodontitis and healthy peers.
Methods & Materials: In this matched case-control study, 106 participants (53 patients with chronic periodontitis and 53 healthy controls) were studies after signing a informed consent form. They were matched for age, gender, weight, and Body Mass Index (BMI). The GCF and salivary samples were collected from all participants and were assessed using standard Enzyme-Linked Immunosorbent Assay (ELISA). The statistical analysis was conducted in Stata V. 11.
Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.34).
Results: The salivary and GCF periostin levels was significantly lower in patients than in healthy subjects (P<0.001). Moreover, the periostin levels was significantly different based on periodontal parameters (P<0.001).
Conclusion: There is association between the incidence of chronic periodontitis and salivary and GCF periostin levels. Hence, the periostin may act as a potential biomarker for the diagnosis  of chronic periodontitis and prevention of its progression.

Azadeh Safari, Mehdi Moradi, Mojtaba Khansooz,
Volume 23, Issue 2 (June & July 2020)
Abstract

Background and Aim: The purpose of this study was to investigate the effect of eight weeks of aerobic exercise and the consumption of kefir dough on anthropometric indices, plasma lipid profile and blood pressure in overweight non-athletic women.
Methods & Materials: This quasi-experimental study was performed on 32 non-athletic women with overweight in Arak, Iran (mean age= 33.94±8.58 years, mean height= 1.59±0.05 cm, mean weight= 70.15±6.88 kg, and body mass index= 27.35±1.50 kg/m2) who were voluntarily selected and randomly divided into four groups of 8 (control, exercise, exercise + supplement, and supplement). The control group had a normal diet without exercise; the supplement group received 100 ml kefir dough three meals a day for 8 weeks; the exercise group performed aerobic exercise for 8 weeks, 3 sessions per week, each for 50 minutes. The exercise + supplement group received both aerobic exercise and kefir dough. Blood and anthropometric variables were measured at the beginning and at the end of the intervention. Paired t-test was used to examine the within-group variations and one-way ANOVA to examine the between-group variations. All statistical tests were performed at the significant level of P<0.05.
Ethical Considerations: This study has obtained its ethical approval from the Research Ethics Committee of Qom University (Code: IR.QOM.REC.1398.01).
Results: The combination of kefir dough supplementation and aerobic exercise significantly reduced the mean blood pressure (P=0.003) and BMI (P=0.03) but had no significant effect on total cholesterol (P=0.27), triglycerides (P=0.61), high-density lipoprotein (P=0.16), low-density lipoprotein (P=0.30) and waist-to-hip ratio (P=0.24).
Conclusion: Overweight women can benefit from the aerobic exercise combined with kefir dough supplementation to reduce their blood pressure and BMI. Further studies are recommended to determine the effect of aerobic exercise and kefir supplementation on serum total cholesterol, triglyceride, low- and high-density lipoproteins, and waist-to-hip ratio.

Elaheh Rezaie, Mojtaba Bayani, Mohamohammad Arjomandzadeganmmad,
Volume 23, Issue 2 (June & July 2020)
Abstract

Background and Aim: Although there are methods such as the use of mouthwashes to prevent periodontal diseases, these diseases are still the most common oral diseases. Given the side effects of chemical methods, the present study aimed to evaluate the inhibitory and antibacterial effects of peppermint essential oil on periodontal pathogens.
Methods & Materials: Antibacterial effect of the peppermint essential oil by the disk diffusion and Microplate dilution techniques was performed on 4 standard bacteria purchased from the microbial bank of Iran, including Enterococcus Faecalis, Streptococcus Sanguinis, Eikenella corrodens, and Actinomyces Viscosus. The minimum inhibitory concentration and minimum bactericidal concentration of the essential oil were also evaluated. The amount of biofilm formation was obtained by calculating the average biofilm formation in the three wells and comparing it with the optical density of negative control by the Elisa Reader device.
Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences with code: IR.ARAKMU.REC.1397.15.
Results: Results of diffusion test showed the inhibitory effect of 0.1 g/mL essential oil on Enterococcus Faecalis and Streptococcus Sanguinis. Pure essential oil of peppermint showed the strongest inhibitory effect on streptococcus sanguinis followed by enterococcus faecalis, actinomyces viscosus and eikenella corrodens. 
Conclusion: The peppermint plant has antibacterial and inhibitory effects on the bacteria of enterococcus faecalis, streptococcus sanguinis, eikenella corrodens, and actinomyces viscosus. Therefore, peppermint as a natural and effective antibacterial agent, has a potential application in the prevention of periodontal disease.

Kurosh Farhadtoski, Mojtaba Bayani, Hamid Sarlak, Zohreh Salimi,
Volume 23, Issue 2 (June & July 2020)
Abstract

Background and Aim: Chronic periodontitis is the most prevalent form of periodontitis and it generally considered as a progressive inflammatory disease. Environmental and systemic factors can alter the immune response to biofilm and lead to progressive degenerative disease. Chronic periodontitis is defined as an infectious disease that causes inflammation in the tooth-supporting tissues, periodontal attachment loss, and bone loss. Identification of risk factors for this disease is important. Hence, this study aims to evaluate the risk factors for chronic periodontitis.
Methods & Materials: This case-control study was conducted on 120 periodontitis patients and 120 healthy controls in Arak, Iran. A questionnaire was used to estimate their Socio-Economic Status (SES) and survey demographic and risk factors. For the diagnosis of chronic periodontitis, the identification of plaque accumulation site and clinical examination were performed. To investigate the association of chronic periodontitis with study variables, multilevel logistic regression analysis was used in STATA V. 11 software. 
Ethical Considerations: This study obtained its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences under code: 1397.145.
Results: The Odds Ratio (OR) of chronic periodontitis in adults aged above 30 years was 2.91 (95% CI: 1.01-8.73). Compared to subjects with low SES, the OR of chronic periodontitis was 2.28 (95% CI: 1.22- 4.27) in those with moderate SES and 0.89 (95% CI: 0.79-0.98) in those with high SES. Compared to patients who did not brush their teeth, the OR of chronic periodontitis was 0.67 (95% CI: 0.39-0.89) in patients reported toothbrushing. Compared to those who reported changing toothbrush sooner than 3 months, the OR was 4.96 (95% CI: 2.27-11.3) in those their changed their toothbrush for more than 6 months interval. The OR of chronic periodontitis in current smokers was 3.09 (95% CI: 1.52-4.76).
Conclusion: Cigarette smoking, alcohol consumption, tooth brushing, and SES are the risk factors associated with chronic periodontitis.
Alireza Amani, Ali Kamali, Bahman Sadeghi, Ali Reza Sistani, Mahdi Tavakolizadeh, Sajad Ghodibigi, Farid Saghabi, Mojtaba Ahmadlou,
Volume 23, Issue 4 (October & November 2020)
Abstract

Background and Aim: Ankle injuries are among the most common musculoskeletal injuries in sports, accounting for 10% to 15% of all injuries. Since controlling pain and inflammation in ankle sprains is one of the main goals of treatment, we decided to compare the therapeutic effects of Cheleh daghi Herbal ointment with a common therapeutic gel such as piroxicam.
Methods & Materials: This study was performed as a double-blinded clinical trial for 6 months from January 2019 to August 2019. After referral, all patients completed the consent form, and the patient's details and study variables were recorded by the evaluator in the research form. To measure joint inflammation, we measured the ankle with a meter tape in the ankle area (cm) and recorded. A goniometer was also used to measure the degree of ankle movements. The symptoms of ankle ecchymosis were also checked by physical examination and observation and recorded in the checklist. Statistical analysis was performed in SPSS V. 18 using statistical tests (the Mann-Whitney U test, the Chi-square, and the independent t-test).
Ethical Considerations: The Research Ethics Committee of Arak University of Medical Sciences approved the study (Code: IR.ARAKMU.REC.1396.55) and registered by the Clinical Trial (Code: IRCT2017071720258N53).
Results: The Mean±SD age in the control group was 34.2±8.6 years, and in the case group was 35.4±8.9 years. There was no statistically significant difference according to the Mann-Whitney U test (P<0.05). Also, the Mean±SD height in the control group was 1.7±0.12 m and in the case group was 1.72±0.11 m. The results also showed a statistically significant difference between the two groups studied before and after the intervention regarding the mean indicators of pain, swelling, and inflammation around the joints (P<0.05).
Conclusion: The results of our study showed that Cheleh daghi Herbal ointment for 3 weeks could be more effective in reducing local pain and inflammation than piroxicam gel treatment.
Seyyed Mehrzad Shaddel, Masoud Bayat, Mojtaba Bayani, Vahideh Nazari,
Volume 24, Issue 2 (June & July 2021)
Abstract

Background and Aim: Considering the increasing use of dental implants in replacing lost teeth, the odds of failure over time in this treatment are inevitable, as with other dental treatments; thus, it requires careful and regular follow-up. Accordingly, the present study aimed to evaluate the awareness and attitude of general dentists about the follow-up of the dental implants to create baseline information to schedule future workshops concerning dental implants.
Methods & Materials: In this analytic cross-sectional study, 98 general dentists of Arak City, Iran were evaluated. Questionnaires were designed in 3 sections, as follows: demographic, awareness, and attitude. After checking the validity and reliability of the questionnaires, they were distributed among the research participants. The obtained data were analyzed using descriptive analysis, Chi-squared test, and Independent Samples t-tests. The significance level was considered 0.05.
Ethical Considerations: This article was approved by the Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.283).
Results: The average score of awareness of the questionnaires was equal to 10.8 (based on the score of 0-19); the mean score of attitude was measured as 12.8 (based on the score of 7-21). Fifty-Three of the explored dentists had performed implant treatment, whose awareness and attitude toward implants follow-up were significantly higher than those of the dentists who did not perform such treatment (P=0.0001). Work experience presented no significant effect on the examined dentists’ awareness and attitude (P>0.05).
Conclusion: General dentists have low awareness and attitude about implant follow-up. Follow-up plays an important role in the long-term success of implant therapy; therefore, dental education/retraining programs should be reviewed in this field.

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