Showing 161 results for Ag
Nahal Moharekpour, Vahab Habibipour, Davood Shamci,
Volume 25, Issue 2 (5-2022)
Abstract
Background and Aim Crisis management is an important field of management, especially in the field of health. This study aims to investigate the factors affecting the development of disaster management mechanisms in hospitals of Arak, Iran.
Methods & Materials In this regard, 240 questionnaires were distributed among hospital and nursing managers in Arak. The questionnaire had acceptable reliability with Cronbach’ alpha value of 0.897.
Ethical Considerations This study was approved by the ethics committee of Arak University of Medical Sciences (code: 1274.1401.REC.ARAKMU.IR).
Results Then, by using structural equation modeling in LISREL software, the designed model was analyzed. Finally, by using statistical tests, the research hypotheses were examined.
Conclusion The results showed the significant effect of three factors of “lack of stability in business environment”, “risk taking”, and “organizational culture” on the development of the mechanism of crisis management.
Mahmood Haghiri, Vahab Habibpour, Nahal Moharekpour, Morteza Ghasemi,
Volume 25, Issue 2 (5-2022)
Abstract
Background and Aim This study aims to investigate the effect of nurses’ autonomy on the quality of patient care based on Kramer and Schmalenberg’s model
Methods & Materials This is a causal-comparative study. Participants were 101 nurses of Imam Khomeini Hospital in Arak, Iran from the intensive care unit and internal medicine, surgery, pediatrics, gynecology, orthopedics, and emergency departments. The data collection tools were Moghimi and Ramazan’s patent care quality questionnaire and an autonomy assessment questionnaire based on Kramer and Schmalenberg’s autonomy model. The data were analyzed in SPSS software.
Ethical Considerations This study was approved by the ethics committee of Islamic Azad University of Arak Branch (Code: IR.IAU.ARAK.REC.1397.66).
Results The mean autonomy score of nurses was 3.16 ±0.35, indicating a desirable level. Nurses of all departments had limited autonomy. In the internal department, nurses had unsanctioned autonomy, while in the surgical department, they had autonomous nursing care action. The regression models were significant for all departments except for the internal department. With an increase of one unit in limited autonomy in the intensive care unit, autonomous nursing care in the surgical department, and limited autonomy in pediatrics, gynecology, orthopedics, and emergency departments among the nurses, the quality of care can be increased by 0.253, 0.187, 0.522, 0.205, 0.466 and 0.129, respectively.
Conclusion Nurses’ autonomy can increase the quality of patient care. The nursing managers need to empower nurses and provide an environment for them to apply their knowledge in practicing autonomy.
Fatemeh Mohammadi, Maryam Nikrou, Kimia Sadeghi, Farid Askarifard, Mohammad Sayyadi,
Volume 25, Issue 2 (5-2022)
Abstract
Background and Aim Coronavirus disease 2019 (COVID-19) is a respiratory disorder that can affect many body systems, including the hemostatic system. In this study, we aim to investigate the role of hemostatic system and the blood coagulation in COVID-19.
Methods & Materials In this review study, the articles were searched using the keywords COVID-19, Respiratory infection, and Coagulopathy in Google Scholar, PubMed, Google Springer and Science Direct databases.
Ethical Considerations Ethical principles in writing this article were observed in accordance with the guidelines of the National Ethics Committee and the Committee on Publication Ethics (COPE).
Results Many changes in the coagulation profile of infected patients were reported, including changes in the platelet count, fibrinogen/fibrin degradation product, D-Dimer, fibrinogen, prothrombin time, and activated partial thromboplastin time. With the increase in the number of patients with COVID-19, several studies found out the occurrence of thrombosis and coagulopathy in patients.
Conclusion Due to the increase in the occurrence of coagulation disorders in patients with COVID-19, the administration of anticoagulants is needed for their treatment; it can play an effective role in improving the prognosis of patients.
Sousan Salehi, Maryam Tarameshkou, Saeed Mirahmadi, Saghar Hashemnia, Milad Hassansheikhi,
Volume 25, Issue 3 (8-2022)
Abstract
Background and aim: It is suggested that hearing impaired children with hearing aids and cochlear implant, showed poor pragmatic abilities. Pragmatic is the most related language component to social interaction. Further, it has effect on personality development and self-esteem. The main aim of the present study is investigating the relationship between pragmatic abilities and self-esteem in hearing impaired children.
Materials and methods: Sixty hearing impaired children with hearing aids or cochlear implant were included into this study according to inclusion and exclusion criteria. Then parents or other caregivers were asked to fulfill Children’s Communication Checklist (CCC) and self-esteem questionnaire. The participants were divided into three groups based on hearing impairment severity, including: severe, moderate and mild. The relationship between pragmatic ability and self-esteem was examined in three groups and without considering categorization, by Pearson correlation coefficient, significant level was 0.05.
Ethical considerations: This project is approved in Arak university of medical sciences with ethical registration code IR.ARAKMU.REC.1399.150. All parents gave written informed consent form.
Findings: the results illustrated that there is significant relationship between pragmatic abilities and self-esteem in all hearing impairment children without considering categorization (p<0.05). By considering categorization, significant relationship was showed in self-esteem and pragmatic abilities in moderate and mild groups (p<0.05).
Conclusion: according to our analysis, pragmatic abilities and self-esteem are related. This relationship is more obvious in low severity impairment.
Mrs. Mahnaz Ghahramani Til, Mrs. Rezvaneh Sadat Fatemi, Dr. Rahman Shokri, Dr. Mahdi Banitalebi Dehkordi, Dr. Mahdi Paryan,
Volume 25, Issue 4 (9-2022)
Abstract
Introduction: Salmonella infection (salmonellosis) is a common bacterial disease that affects the intestinal tract. Several methods like Multiplex or real-time PCR, ELISA, and Agglutination are used to identify these bacteria. However, normally rapid, cost effective and easy diagnostic methods such as agglutination test is recommended. In Iran, positive control antiserums used in diagnostic kits work based on polyvalent agglutination and are against O and H antigens. The purpose of this research was to produce specific anti-sera against O and H antigens for using in agglutination and ELISA kits.
Methods: New Zealand white rabbits were immunized by intravenous injections of inactivated bacterial O and H antigens adjusted to a cell density equivalent to a turbidity of a McFarland number 3 standard. Serum collection was performed 7 days after the last injection. Collected Antisera were tested with positive human specimens as well as cross-reaction antibodies. Absorption method was used to obtain specific anti-sera against O and H antigens. Produced Anti-O and Anti-H antibodies were mixed with bacterial H and O antigens respectively and incubated for 1 hours in 37˚c. The Mixture was centrifuged and the supernatant was collected. Furthermore, in order to use these antisera in specific kits such as ELISA, Immunofluorescence etc., purification methods like Ammonium sulphate precipitation, tangential Flow Filtration and Chromatography were performed. This study was approved by the ethics committee of Pasteur Institute of Iran (Code: IR.PII.REC.1399.006).
Results: Results of agglutination test before and after adsorption showed cross-reaction before adsorption and no cross-reaction with H and O antigens with monospecific antisera against O and H after adsorption, respectively. Moreover, high quality and quantity of mono-specific antibody was obtained after purification.
Conclusions: Serum-based assays are recommended for the timely diagnosis of the disease since these assays are specific, sensitive, inexpensive, and rapid. Therefore, the produced antiserum in the present research can be used in primary screening of salmonella infections based on agglutination tests which are cost effective and simple. In addition, purified anti-sera can be used in the development of ELISA and Immunofluorescence assays.
Mr Mohsen Shamsi, Mr Ali Kulivand, Mr Mohammadjavad Ghannadzadeh, Ms Mahboobeh Khorsandi, Mr Seyedhamed Mirhosseini, Mr Amir Almasi-Hashiani, Mr Behrooz Karimi, Mr Seyednadali Alavi Bakhtiarvand, Ms Masoume Naderi Noreyni,
Volume 25, Issue 4 (9-2022)
Abstract
Introduction: Today, with the increase in population, the per capita production of waste materials and the subsequent threat and destruction of the environment is an increasing process, and waste management by the people of a society can play an essential role in reducing this problem. Therefore, the aim of this study was determine of predicting the waste management behaviors of households in Arak city in 2022.
Methods: This is a cross-sectional and analytical study that was carried out on 600 mothers of households in Arak city, who were selected by multi-stage sampling. The data collection tool was a valid and reliable researcher-made questionnaire that included demographic characteristics, knowledge, attitude and behavior of households in the field of waste management. Data were analyzed using SPSS software and t-test, chi-square and regression tests. This study was approved by the research ethics committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1401.040).
Results: The average age of the studied was 39±11 years and the number of family members was 3.6. In terms of type of housing, most of them lived in apartments (44%) and a smaller number lived in complexes (14%). 65 percent of the people had not received the training on the waste separation plan from the source, and among the effective training methods, the majority (38 percent) of the people had overestimated the effectiveness of the training through the Internet. The mean and standard deviation of knowledge was 66±19, attitude was 84±11 and performance was 73±18. The majority of the people studied had a good level of awareness and attitude. The regression analysis model showed that the greatest impact on the waste management behavior of the samples was the age of the people, their knowledge and attitude, which predicted a total of 33% of the waste management behavior.
Conclusions: Considering the favorable state of awareness and attitude of households in Arak city, it seems that for better waste management, other environmental factors should be emphasized, including sources of waste production at the source. Also, based on the prediction model, it is still important to inform and change the attitude of households in Arak city for better performance at younger ages.
Dr. Mojtaba Bayani, Dr. Shirin Shafiei Lialestani, Dr. Amir Almasi-Hashiani, Dr. Seyed Hamed Mirhoseini,
Volume 25, Issue 5 (12-2022)
Abstract
Introduction: Dental unit water lines (DUWL) are a potential place for the accumulation of microorganisms and the formation of microbial biofilm, which exposes people to infection risk. This study aimed to investigation of the effectiveness of four commonly used substances and selection of most effective disinfectant in DUWLs disinfection.
Methods: This systematic review study was conducted based on PRISMA templates and the PubMed, Scopus and Web of Science databases with a specific search strategy were examined. In this systematic review study, the effectiveness of 4 disinfectants including: hydrogen peroxide, chlorhexidine, chlorine-dioxide, sodium hypochlorite on microbial biofilms in the DUWL was investigated. The study was conducted on July 10, 2021, and finally the data of all studies related to the subject of this systematic review were extracted. This study was approved by the Research Ethics Committee at Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1399.347).
Results: All four disinfectants in sufficient concentration and time can be useful and effective. If the biofilm in DUWL is old and stabilized, it will affect the effectiveness of these materials and it will take longer to remove.
Conclusions: The use of materials in combination can cover all the microbial spectrum present in the biofilm of this area, and even fixed biofilms can be removed with extended and continuous use.
Miss Homa Rastegari, Dr Davood Hekmatpou, Dr Ramiz Kamrani, Dr Moloud Farmahini Farahani,
Volume 26, Issue 1 (4-2023)
Abstract
Introduction: One of the common problems of patients with covid-19 is the occurrence of respiratory problems that may accompany the person for a long time. Also, based on clinical and research evidence, different degrees of anxiety and stress have been observed in those who have recovered from this disease. This study was conducted with the aim of determining the effect of diaphragmatic breathing on dyspnea and state anxiety in patients with covid-19.
Methods: This study was a randomized clinical trial conducted in 2021-2022. The study population consisted of 78 patients with covid-19 hospitalized in Amir al-Momenin Hospital in Arak city, who were selected by available sampling and divided into two groups of 40. In this study, the Spielberger anxiety inventory, Borg scale, MRC breathlessness scale and measurement of blood oxygen saturation were used. The test group received diaphragmatic breathing training on the day of discharge and performed the exercise for ten minutes, and after discharge, they performed diaphragmatic breathing twice a day (ten minutes each time) at home for a week. Questionnaires were completed by the patients before the intervention, immediately after and one week later. The data was analyzed with SPSS software version 23 at the level (P < 0.05).
Results: The findings showed that the mean anxiety score of the patients immediately and one week after the intervention in the test group was significantly lower than the control group (P < 0.001). The mean oxygen saturation in the test group after the intervention was significantly higher than the control group (P < 0.001). Also, a significant difference was observed between the mean dyspnea scores using the MRC and Borg dyspnea scales after the intervention in the two groups (P < 0.001).
Conclusions: The results showed diaphragmatic breathing reduced anxiety and shortness of breath in patients with covid-19 after discharge. Therefore, teaching this simple and effective method is recommended for these patients during discharge from the hospital.
Dr Sina Banijamali, Dr Oldooz Aloosh, Dr Vahan Moradians, Dr Tayeb Ramim, Dr Haleh Afshar,
Volume 26, Issue 3 (9-2023)
Abstract
Introduction: Patients with COVID-19 can have various and complex coagulation disorders that cause hypercoagulable conditions. Investigating the role of anticoagulants with different doses in the outcome of patients with COVID-19 seems to be needed. Therefore, the present study was conducted with the aim of predicting factors of severe disease, including the number of lymphocytes, LDH, and the recovery status of patients.
Methods: A cross-sectional study was conducted in patients with COVID-19 hospitalized in Hazrat Rasool Akram (PBUH) Hospital. Study entry includes acute respiratory symptoms caused by COVID-19 disease (uncontrollable cough, dyspnea, prolonged medicine and blood saturation drop) along with lung involvement in chest spiral CT scan without injection, SARS RT-PCR–CO virus test was positive and transfer to intensive care unit (ICU) was indicated. Anticoagulant starting time, type and dose of anticoagulant received and duration of use were recorded. Two groups of prophylaxis dose, higher dose than prophylaxis (medium dose and therapeutic dose) were divided.
Results: Out of the total number of patients referred to Rasul Akram Hospital, 90 people (43 women (47.8%) and 47 men (52.22%)) participated in this study. The average hospitalization in the ICU was 13.50 ± 12.39 days and 17.18 ± 13.36 days in the hospital. Also, the duration of coagulant therapy was 17.13 ± 13.38 days. 53 patients (58.9%) received a prophylactic dose, 28 patients (31.1%) received a therapeutic dose, and 9 patients (10%) received a moderate dose of anticoagulant. Anticoagulant in 74 patients (82.2%) was unfractionated heparin (UFH) and in 16 cases (17.8%) low molecular weight heparin (LMWH). The changes of LDH, number of lymphocytes, dimer, fibrinogen, ferritin and FDP according to the dose of anticoagulant assessed in the three groups of prophylaxis, treatment and no statistically significant difference. The mean of ICU admission days according to different doses of anticoagulant did not show a statistically significant difference.
Conclusions: Finally, the findings obtained from the study showed that the use of different doses of anticoagulant does not cause a difference in the level of LDH, number of lymphocytes, ferritin and FDP at different measurement times. Also, the length of stay in the hospital and the time of hospitalization in the intensive care unit did not differ between the groups receiving prophylactic anticoagulant, medium dose and therapeutic dose.
Shiva Kavousinejad, Mohadese Shokripour, Bahareh Asgartooran, Zahra Cheraghi,
Volume 26, Issue 4 (11-2023)
Abstract
Abstract
Background and Aim: This study aimed to compare the microleakage of an adhesive fissure sealant (AFS), a flowable composite resin (FC), and a resin-modified glass ionomer (RMGI) in permanent teeth.
Materials and Methods: This in vitro, experimental study was conducted on 45 extracted posterior teeth with sound fissures. The teeth were randomly divided into 3 groups (n=15). The occlusal fissures were sealed with Beautisealant AFS without etching and bonding in group 1, with Beautifil FC after 37% phosphoric acid etching in group 2, and with Fuji II LC RMGI in group 3. The teeth underwent 500 thermal cycles (5-55°C), and their apices were sealed with wax. They were then immersed in 2% methylene blue for 24 hours. Next, the teeth were sectioned buccolingually and inspected under a stereomicroscope to measure the dye penetration depth as an indicator of microleakage. Data were analyzed by ANOVA, Chi-square test, and Scheffe test (alpha=0.05).
Ethical consideration: The study was approved by the ethics committee of Hamadan University of Medical Sciences (IR.UMSHA.REC.1399.728).
Findings: The microleakage score of RMGI was significantly higher than that of AFS and FC (P<0.05), while the microleakage scores of FC and AFS were not significantly different (P=0.330).
Conclusion: The AFS showed a sealing ability comparable to that of FC, and can be used as an alternative to FC due to its fewer application steps.
Zahra Hassanbeigi, Fereshteh Bamdad, Kourosh Bamdad,
Volume 26, Issue 5 (12-2023)
Abstract
Introduction: Nowadays, due to the increasing spread of electronic devices and digital transmitters, the general public is exposed to electromagnetic waves with different wavelengths. According to the function of the thyroid gland on the metabolic actions of the body, the purpose of this study was to investigate the changes in the serum level of thyroid stimulating hormone after receiving short-term and long-term electromagnetic waves emitted from home Wi-Fi.
Methods: 60 rats in the weight range of 250-300 grams were randomly divided into 3 equal groups. The first group did not receive any waves. The second group was placed near Irancell's portable Wi-Fi device for 10 days,1 hour a day, and the third group was near Wi-Fi waves for 3 hours a day for a month. After one month, blood was taken from the mice and the serum level of thyroid stimulating hormone was measured.
Results: The data analysis showed that the serum level of thyroid stimulating hormone in the group that was exposed to medium-term Wi-Fi waves was significantly different from the control group, but the level of this hormone in the group that was exposed to the waves for a short period of time, it was not significant in comparison with the control group.
Conclusions: According to the present results, it is possible that electromagnetic waves lead to hormonal disorders in the body, and one of these disorders can be a change in the amount of thyroid stimulating hormone.
Mahnaz Shokri, Nabiollah Akbar Nataj Shub, Jamal Sadeghi, Arsalan Khanmoham Otaghsara,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: Several factors influence students' behaviors and develop motivation. Meanwhile, cognitive factors such as psychological capital play a more prominent role than others, and it is crucial to understand the factors that affect them. The current research purpose was to compare the effectiveness of mindfulness intervention and cognitive-behavioral game therapy on the psychological capital of female first-secondary school students in Amol City.
Methods: The research method was semi-experimental with a pre-test-post-test design with a control group. The statistical population included all the female students of the first secondary school of the seventh grade of the public schools of Amol City in the academic year of 2023. Among them, 45 people were selected by the available sampling method and were replaced randomly and by lottery in two experimental and control groups (30 individuals in the experimental group and 15 people in the control group). The people attending the first experimental group received mindfulness intervention (8 sessions) and two sessions per week for 60 minutes, and the second experimental group received cognitive-behavioral game therapy intervention (10 sessions) and two sessions per week for 30 minutes. The questionnaire used in this research included psychological capital. The study data was analyzed using the repeated measures analysis of variance (ANOVA) method.
Results: The findings showed that mindfulness and cognitive-behavioral game therapy affected the psychological capital of female students of the first secondary school in Amol City (P < 0.01). Also, mindfulness training on psychological capital was more effective than cognitive-behavioral game therapy (P < 0.01).
Conclusions: Although both methods of mindfulness training and play therapy improved students' psychological capital, the approach and method used in each are different. Mindfulness training focuses more on awareness and the presence of the mind in the present moment. At the same time, play therapy focuses more on strengthening psychological skills and abilities through interactive activities and games, which can better capitalize on increased psychological.
Soraya Soheili, Razieh Peyghambardoost,
Volume 27, Issue 2 (5-2024)
Abstract
Introduction: The postpartum period is a dangerous potential time for postpartum depression. Postpartum depression is the reducer instrument for postpartum support. The purpose of the current study is to determine the effectiveness of postpartum supports on the postnatal women depression after childbirth.
Methods: This study a semi experimental study was conducted in Marand hospital. Two hundred sixty mothers agreed to take part and were randomly allocated to an intervention group
(n = 130) or control group (n = 130). The intervention group received telephone counseling for 20- minute at the first week twice, second week till 6th weeks once at week plus routine care. The control group received only the routine care. Also for evaluation of the unanticipated mother’s needs, 24-hour telephone access to researcher was provided. The main outcome measure was recording demographics data sheet, postpartum problem’s checklist and the Edinburgh Postnatal Depression Scale (EPDS) administered by presence interview questionnaire at six weeks after delivery. Control group received general postpartum education. The data were analyzed by χ², Fisher test and T test.
Results: At 6 week postpartum, mean of depression was obtained in the intervention group (15/80 ± 5/12) and in the control group (18/43 ± 5/90). On the EPDS scale, in the intervention group was significantly decrease to control group (P < 0.0001).
Conclusions: The result of this research showed that Postpartum Fallow Up by midwife could effective to decrease women’s postpartum depression in the pureperium.
Seyedeh Midya Khosravi, Morteza Azizi, Hajar Aghaei, Hajar Aghaei,
Volume 27, Issue 2 (5-2024)
Abstract
Introduction: Postpartum depression is a type of mood disorder that can affect pregnant women who have given birth and is affected by various factors, so the present study aims to predict postpartum depression based on marital satisfaction, satisfied body, and dysfunctional beliefs in women of Bukan City.
Methods: The present study is descriptive-correlational. The population consisted of all women with pregnancy in the last month in the first half of 2022 in the city of Bukan in the number of 2980 according to Morgan's table and with informed written consent, 340 pregnant women referring to Shahid Qolipur Hospital in Bukan were selected by available sampling method and filled in the questionnaire. Beck-2 depression, Edinburgh postpartum depression, Enrich's marital satisfaction, Body image satisfaction, and Weisman and Beck's dysfunctional beliefs responded. The analysis was done using a stepwise regression method.
Results: Marital satisfaction, physical satisfaction, and dysfunctional beliefs have a significant ability to predict postpartum depression at P < 0.01 level. This effect is inverse in marital and physical satisfaction and positive in dysfunctional beliefs. Also, marital satisfaction, with an effect size of 0.324, physical satisfaction, with an effect size of 0.497, and ineffective beliefs, with an effect size of 0.652, explain the postpartum depression variable. Also, the prevalence of postpartum depression among women in Bukan City is 30.6%, which is higher than the average of the articles recorded in this field.
Conclusions: According to the results of the research, Marital satisfaction, physical satisfaction inversely, and dysfunctional beliefs directly and positively predict postpartum depression in pregnant women.
Amir Najafi, Mohammad Amin Momeni-Moghaddam, Dr Davoud Salarbashi, Narges Amini Beidokhti, Marziye Rahmani, Milad Khorasani,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Type 2 diabetes is a non-communicable disease that imposes a significant financial burden on the healthcare system each year. Numerous studies have demonstrated the involvement of inflammatory factors in the initiation and progression of this condition. The primary goal of this study is to compare the polymorphism of the interleukin 1 receptor antagonist gene among individuals with type 2 diabetes and those in the control group.
Methods: Following approval from the Ethics Committee of Gonabad University of Medical Sciences, blood samples were collected from 100 participants at Bohlool Hospital in Gonabad. These individuals were categorized into two groups: cases (individuals with type 2 diabetes) and controls (healthy individuals). DNA extraction was carried out using the salting out method. To examine the polymorphism, the specific segment was initially amplified through PCR with designated primers and then identified via gel electrophoresis. The data were analyzed using subjected to the Chi-square test at a significance level below 5%.
Results: Findings from the polymorphism analysis revealed a notable contrast in the genotype 2/1 (P = 0.001) and 2/2 (P = 0.004) within the case group when compared to the healthy participants. Specifically, individuals with genotype 2/1 exhibited a heightened risk of developing type 2 diabetes by up to 15 times.
Conclusions: Within the examined population, the polymorphism of the interleukin 1 receptor antagonist gene substantially influenced the predisposition to type 2 diabetes, amplifying the likelihood of developing this ailment. Individuals harboring allele 2 are at an increased susceptibility to type 2 diabetes.
Mohammad Douzandeh Nargesi, Zohreh Teymori, Mehnoosh Tavakkolifard,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: The stress caused by COVID-19 had affected many people in society, especially individuals at risk. The present study was carried out to investigate, firstly, whether COVID-19-related stress plays a mediating role in the relationship between rumination and aggression in drug-dependent people undergoing treatment. Secondly, the study was conducted to know whether rumination has an indirect effect on the aggression of substance-dependent people under treatment through the mediation of COVID-19-related stress.
Methods: In this correlational analytical study, 136 patients undergoing maintenance treatment with methadone who were willing to enter the study were investigated by the available sampling method in two addiction treatment centers in the 1st and 2nd districts. The data collection tools in the present study included the Corona Disease Anxiety Questionnaire, Rumination Questionnaire, and Bass and Perry Aggression Questionnaire. After collecting the data, the anxiety score of each participant was measured from 0 to 54, the rumination score from 0 to 88, and the aggression score from 29 to 145. Then, the data was analyzed using Lisrel statistical software.
Results: Findings showed that the direct effect of rumination on aggression is 0.23, which is significant at the P < 0.01 level. Therefore, rumination has a positive and direct effect on aggression. Also, COVID-19-related stress plays a mediating role in the relationship between rumination and aggression in drug addicts under treatment. In addition, the indirect effect of rumination on aggression is 0.25, which is significant. Thus, rumination has an indirect effect on aggression through the mediation of COVID-19-related stress.
Conclusions: According to the high prevalence of psycho-social problems such as depression, anxiety, fear, addiction, job burnout, suicidal thoughts, violence, domestic and post-traumatic stress during the COVID-19 pandemic, in the post-corona era, we have witnessed a high amount of mental and social injuries in the world. For this reason, governments must screen psychologically vulnerable groups in advance.
Malihe Keykhapour, Javad Baharara, Hamed Hatami, Maryam Lotfi, Sajad Farrokhyar,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Harmine is an alkaloid from the carboline family, belonging to the harmal plant, which has extensive applications in traditional medicine, with numerous studies highlighting its anti-cancer effects. Since biological processes are influenced by electromagnetic fields, the current study examined the anti-cancer effects of harmine and low-frequency electromagnetic fields on the expression of COX2, VEGF, and MMP-2 genes in the A2780 cell line.
Methods: In this experimental-laboratory study, ovarian cancer cell lines were randomly divided into four groups: control, harmine at concentrations of 6, 12, 24, 48, 96, and 192 micromolar, low-frequency electromagnetic field with an intensity of 50 Gauss, and harmine at a concentration of 48 micromolar with a low-frequency electromagnetic field of 50 Gauss intensity. Their toxicity was assessed using the MTT assay, nuclear morphological changes by DAPI staining, apoptotic effects of these compounds by measuring nitric oxide (NO), and gene expression changes by Real-Time PCR. Quantitative data were analyzed the ANOVA statistical test at a P < 0.05 level.
Results: Quantitative data comparison of this research indicated that harmine and a low-frequency electromagnetic field with an intensity of 50 Gauss caused a concentration-dependent reduction in the viability of ovarian cancer cells. Additionally, in the nitric oxide test, a significant decrease was found in the control group compared to the groups treated with a concentration of 48 micromolar and synergized with a 50 Gauss electromagnetic field (p<0.05). The expression of the aforementioned genes in treated cells showed a significant decrease. Treating ovarian cancer cells with harmine and its combined application led to significant nuclear morphological changes, including chromatin condensation, formation of apoptotic bodies, and wrinkling of the cell membrane.
Conclusions: The combined application of harmine and a low-frequency electromagnetic field induced apoptosis in A2780 cancer cells and resulted in the downregulation of COX2, VEGF-A, and MMP-2 gene expression. Consequently, the combined use of harmine with a low-frequency electromagnetic field, due to its effective cytotoxicity in inhibiting proliferation and inducing apoptosis, could be a suitable candidate for clinical studies.
Marzieh Ganjavi, Alireza Manzari Tavakoli, Zahra Zeinaddiny Meimand,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Delinquency is a serious challenge for teenagers and has significant negative social effects. The main goal of this research was to find out the structural equation modeling of extraversion and delinquent behavior disorder: the mediating role of moral intelligence among the juveniles of Kerman Correctional Center.
Methods: This was a descriptive correlational research of structural equation model type. The statistical population of this research was made up of 80 juveniles of Kerman Correctional Center, who were selected and studied by simple random sampling using Morgan's table. To collect information, Hans Eysenck's (1963) Personality Type Questionnaire, Goodman's Conduct Disorder Questionnaire (1997), Aiti Juvenile Delinquency Questionnaire (2013) and Link and Keel's Moral Intelligence Questionnaire (2005) were used. Descriptive and inferential statistics (structural equation modeling) were used for data analysis through SPSS-28 and Smart PLS-3 software.
Results: The results of this research showed that there is a direct and positive relationship between extraversion and juvenile delinquency. There is a significant direct and positive relationship between conduct disorder and juvenile delinquency. There is a direct and positive relationship between extroversion and moral intelligence of teenagers. There is a significant direct and negative relationship between conduct disorder and moral intelligence of adolescents. There is a direct negative relationship between moral intelligence and delinquency. There was no relationship between extraversion and juvenile delinquency as a mediator of moral intelligence. There was no relationship between conduct disorder and juvenile delinquency with the mediating role of moral intelligence.
Conclusions: According to the results, it can be acknowledged that moral intelligence is an effective component of delinquency affected by extroversion and behavior disorder in teenagers. Therefore, education and training programs should be implemented to strengthen moral intelligence in schools and families, because these programs can strengthen moral skills and moral decision-making power in teenagers and help reduce behavioral disorders and, as a result, delinquency.
Leila Ghanbari-Afra, Mina Gaeeni, Jafar Shahbazpour,
Volume 27, Issue 4 (10-2024)
Abstract
Introduction: The fundamental role of marital satisfaction is vital in family formation and marriage survival. Marital dissatisfaction can make couples fail to solve their conflicts. Marital discontent, combined with job-related stress such as pre-hospital emergencies, can lead to heightened conflict in job responsibilities. It leads to the effect on personnel, patients, and their families. Therefore, this study aimed to investigate the marital satisfaction of pre-hospital emergency personnel at Qom University of Medical Sciences in 2023.
Methods: This cross-sectional study was conducted on 200 pre-hospital personnel of Qom University of Medical Sciences in May 2023. The sampling method was a stratified cluster. The data collection tool included the "Demographic Information" checklist and Enrich's "Marital Satisfaction" questionnaire. Data analysis was done using descriptive tests, Independent T-test, and Regression.
Results: The average age of the participants was 37.3 ± 7.06. More than half of the participants had a bachelor's degree. Most people had rotating shifts. The average score of marital satisfaction was 145.94 ± 22.21. Based on the results of the multivariate regression test, the variables of education, employment status, work experience, type of shift, having a second job, and having a job other than medical staff explain 63% of the variance of marital satisfaction of pre-hospital personnel.
Conclusions: According to the findings of the present study, in general, the marital satisfaction of pre-hospital emergency personnel of Qom University of Medical Sciences is at an average to high level. People with a fixed shift, with a second job, high work experience, without a fixed job status, and bachelor's and associate's degrees had less marital satisfaction than others. Therefore, managers and policymakers in the health field must pay more attention to the quality of family life, especially the married life of pre-hospital emergency workers with the mentioned conditions.
Reavan Afshar, Masoud Rahmati, Rahim Mirnasouri,
Volume 28, Issue 1 (3-2025)
Abstract
Introduction: Considering the synthesis and secretion of irisin and BDNF from muscle tissue during exercise and the possible relationship of these factors with improving muscle strength and performance, the present study aimed to investigate the effect of 12 weeks of strength training on muscle strength, body fat percentage, irisin, and BDNF in inactive middle-aged women.
Methods: In a semi-experimental study, 20 inactive middle-aged women (mean age 37.70 ± 5.91 years, weight 79.80 ± 5.82 kg) were selected and randomly assigned to two strength training groups (n = 10) and control groups (n = 10). The training group performed 12 weeks of strength training, three sessions per week at an intensity of 65 to 80% of maximum strength. Then, blood samples were taken using ELISA to measure irisin and BDNF. Independent t-test and Pearson correlation test were used to analyze the data. The significance level (P ≤ 0.05) was considered.
Results: Strength training significantly increased serum irisin concentration (P = 0.035) and serum BDNF concentration (P = 0.058) and also considerably decreased body fat percentage (P = 0.058) in middle-aged women. There was also a positive and significant relationship between lower body strength and serum irisin levels (P = 0.040). The Results from the Pearson correlation test indicate a significant positive relationship between BDNF and upper body strength (P = 0.038).
Conclusions: Based on the results of the present study, it seems that increased secretion of serum irisin and BDNF hormones is related to increased muscle strength following strength training in middle-aged individuals.
