Showing 24 results for Farid
Fatemeh Samimi, Reza Azizi, Farideh Jalali Mashayekhi,
Volume 24, Issue 5 (December & January 2021)
Abstract
Coronavirus disease-19 (COVID-19) is a new member of the coronavirus family causing acute respiratory infection. Patients with COVID-19 have a higher risk of developing oxidative stress during this infection. Moreover, the virus induces ROS production that activates cellular pathways for viral replication.
Nuclear factor erythroid 2-related factor (Nrf2) is a crucial transcription factor in cellular antioxidant defense by mediating Virus-induced oxidative stress and ROS production. This article suggests that an Nrf2 activator may be beneficial in preventing oxidative stress development in COVID-19 patients. Coronaviruses are a significant group of viruses that cause different illnesses in humans and animals. These illnesses can range from the common cold to more severe diseases such as SARS (Severe acute respiratory syndrome), Middle East Respiratory Syndrome (MERS), and COVID-19. COVID-19 is a new viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The main symptoms of COVID-19-infected patients are fever, dry cough, fatigue, and sometimes respiratory problems such as shortness of breath, sore throat, and infection [1].
Fatemeh Mohammadi, Maryam Nikrou, Kimia Sadeghi, Farid Askarifard, Mohammad Sayyadi,
Volume 25, Issue 2 (June & July 2022)
Abstract
Background and Aim Coronavirus disease 2019 (COVID-19) is a respiratory disorder that can affect many body systems, including the hemostatic system. In this study, we aim to investigate the role of hemostatic system and the blood coagulation in COVID-19.
Methods & Materials In this review study, the articles were searched using the keywords COVID-19, Respiratory infection, and Coagulopathy in Google Scholar, PubMed, Google Springer and Science Direct databases.
Ethical Considerations Ethical principles in writing this article were observed in accordance with the guidelines of the National Ethics Committee and the Committee on Publication Ethics (COPE).
Results Many changes in the coagulation profile of infected patients were reported, including changes in the platelet count, fibrinogen/fibrin degradation product, D-Dimer, fibrinogen, prothrombin time, and activated partial thromboplastin time. With the increase in the number of patients with COVID-19, several studies found out the occurrence of thrombosis and coagulopathy in patients.
Conclusion Due to the increase in the occurrence of coagulation disorders in patients with COVID-19, the administration of anticoagulants is needed for their treatment; it can play an effective role in improving the prognosis of patients.
Farideh Barghi, Sahar Safarzadeh, Faremah Sadat Marashian, Saeed Bakhtiarpour,
Volume 25, Issue 6 (February & March 2023)
Abstract
Introduction: Since a more appropriate psychological treatment has not yet been found in the treatment of autism to be a definite solution in autism, in this research, two more common psychological methods have been compared. Objectives The aims of this study were to compare the effectiveness of ABA and Fluortime play therapy on sensory processing in children with autism spectrum disorder in Qom in 1401.
Methods: The method of this quasi-experimental study was pre-test-post-test and follow-up with a control group. The statistical population of the research included all the children with autism in land Qom at Golhay Behesht Autism Center. The statistical sample of this research was 45 people who were selected by available sampling, and randomly divided into three experimental groups using the ABA method (15 people Fluortime method (15 people) and the control group (15 people) were placed. The first experimental group was treated with the method of ABA in the designated sessions. 23 20-minute sessions were presented to the subject group. During experimental group Fluortime was treated with the method of 23 sessions of 20 minutes, it was presented to the subject group, then it was analyzed using analysis of variance with repeated measurements. Ethical Considerations: This article is approved by the ethics committee of Islamic Azad University Ahvaz branch IR.IAU.AHVAZ.REC.1401.032.
Results: The results of the analysis showed that the Flortime play therapy training in sensory processing was significantly at the level of the effect of the implementation of independent variables on the registration components down (P = 0.02) Sensory seeking (P = 0.001) Sensory sensitivity (P = 0.019) Sensory avoidance (P = 0.004) is significant. On the other hand, the average difference of sensory processing components in the applied behavior analysis and game group is significant. Fluortime treatment is significant with the control group. So that the mean of the components of sensory processing in both experimental groups has a significant0.05 ≥ P decrease compared to the control group.
Conclusions: This finding, in line with the change trend of the mean of the components of sensory processing, shows that functional ABA and Fluortime play therapy during the implementation period. And three months after the completion of the implementation period, it has led to a significant decrease in the average scores of sensory processing components. Sensory processing in children with autism spectrum disorder. It should be mentioned that in comparison, the scores of sensory seeking, sensory sensitivity and sensory avoidance in the Fluortime were higher than in the ABA method, and low registration was higher in the ABA method, but the results of the Ben Feroni test show that although each method was significant separately in sensory processing, the difference in effect Functional behavior analysis and Fluortime play therapy on sensory processing components of p>0/05 is not significant.
Parto Hekmatpou, Parnian Hekmatpou, Farideh Jalali Mashayekhi, Sahar Bayat, Milad Gholami,
Volume 28, Issue 1 (3-2025)
Abstract
Introduction: Oculocutaneous Albinism is a hereditary disease with an autosomal recessive pattern. The incidence of this disease is about 1 in every 17 thousand births. Most of the affected people in Iran are the result of consanguineous marriages. White hair, fair skin, and reduction of iris pigments are the main manifestations of this disease. Also, exposure to sunlight increases the susceptibility of these patients to skin cancer. This study aimed to investigate the genetic cause of a person with Oculocutaneous Albinism by whole exome sequencing.
Methods: A 6cc peripheral blood sample was obtained from a child with oculocutaneous Albinism with an autosomal recessive inheritance pattern. DNA extraction and whole exome sequencing were performed. After analyzing the exome sequencing data, the pathogenic mutation was identified. Then, the Sanger sequencing method was used to confirm and segregate.
Results: The affected case showed homozygous pathogenic mutation (NM_000372.5): c.286dupA p.(Met96AsnfsTer73) in exon 1 of the TYR gene. Oculocutaneous albinism IA was determined according to the mutated gene. Also, the parents of the affected person were heterozygous for the mutation.
Conclusions: The mutation causing oculocutaneous albinism was identified in the affected person using the high-efficiency whole exome sequencing method and then confirming the mutation through Sanger sequencing. Considering the parents' consanguineous marriage of the parents, this finding can be used for preventive measures in the future.
