Mohammad Parastesh, Zahra Nadi,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: The present study aimed to investigate the effect of a 10-week resistance training on the serum levels of insulin resistance index (HOMA-IR), the serum levels of liver enzymes, chemerin, and resistin in healthy and type 2 diabetic rats.
Methods & Materials: In this experimental study, 40 Wistar rats with the mean±SD weight of 200±48 gr were randomly divided into 4 groups (normal control, diabetic control, diabetic resistance training, and resistance training). The training groups performed regular resistance exercises for 10 weeks by ladders. Twenty-four hours after the last training session, the blood sample of rats was collected for resistin, chemerin, insulin, and liver enzymes. The obtained data were analyzed using one-way Analysis of Variance (ANOVA), Tukey posthoc test, Analysis of Covariance (ANCOVA), and Bonferroni posthoc test at a significance level of 0.05.
Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences, Iran (Code: IR.ARAKMU.REC.1394.329).
Results: Diabetes induction significantly HOMA-IR, the serum levels of liver enzymes, resistin, and chemerin in the diabetic control group, compared to the healthy control group (P<0.05). Resistance training also significantly decreased insulin HOMA-IR, the serum levels of liver enzymes, resistin, and chemerin in the diabetic resistance training group, compared to the diabetic control group (P<0.05).
Conclusion: The obtained data suggested that resistance training improved liver enzymes in type 2 diabetic rats by decreasing the insulin HOMA-IR, the serum levels of chamirin, and resistin.
Narges Aliniya, Alireza Elmieh, Mohamadreza Fadaei Chafy,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: Non-alcoholic fatty liver disease is a type of accumulation of fat in the liver cells. Moreover, portulaca oleracea has hypolipidemic properties. Accordingly, the present study aimed to investigate the effect of a combination of training and portulaca oleracea supplementation on plasma lipid profile and liver ultrasound in obese women with nonalcoholic fatty liver.
Methods & Materials: The study population consisted of 40 to 60-year-old obese women with non-alcoholic fatty liver disease. In total, 40 obese women with nonalcoholic fatty liver disease were randomly selected and divided into 4 groups. The study groups included training (n=10), training + supplementation (n=10), placebo (n=10) and supplementation (n=10). Before and after the intervention, sonography of the liver and blood tests were performed. The Paired Samples t-test and Analysis of Variance (ANOVA) were used to analyze the obtained data. The significance level was set at P<0.05.
Ethical Considerations: This study was approved by the Research Ethics Committee of Islamic Azad University, Rasht Branch, Iran (code: IR. IAU.RASHT.REC. 1397. 034). Moreover, it was registered at the Iranian Registry of Clinical Trials (IRCT) (code: IRCT201903090429871).
Results: The obtained data suggested that 12 weeks of portulaca oleracea supplementation and combination training significantly decreased the plasma concentrations of cholesterol (P=0.001), triglyceride (P=0.00), LDL (P=0.00), and significantly increased serum HDL levels (P=0.00) in the exercise + supplement, supplement, and exercise groups (P<0.05). Liver ultrasound data also improved in the exercise + supplement (P=0.02), and exercise (P=0.00) groups.
Conclusion: Portulaca oleracea supplementation with combination exercises could be effective in reducing plasma lipids and improving liver ultrasound in obese women with nonalcoholic fatty liver.
Sedigheh Ahmadi, Saeid Toulabi, Hossein Ilanloo,
Volume 23, Issue 1 (3-2020)
Abstract
Background and Aim: Adolescent students are at high risk for substance abuse. The tendency to substance abuse in students is of significant importance. Therefore, this study aimed to investigate the relationship between the tendency to substance abuse based on resilience and procrastination in high school students.
Methods & Materials: This was a cross-sectional and correlational study. The statistical population consisted of high-school male students in district 12 of Tehran City, Iran, in the academic year of 2017-2018. The statistical sample consisted of 149 individuals who were selected using a multistage cluster sampling technique. The data collection instruments were Conner and Davidson’s Persistence Questionnaire (2003), Solomon and Roth Blum (1984), and Golparvar Substance Abuse Tendency Questionnaire (2003). Pearson’s correlation coefficient and regression analysis were used for data analysis.
Ethical Considerations: This study was approved by the Research Ethics Committee of Kharazmi University (Code: IR.KHU.REC1397.29).
Results: The current study results suggested a significant relationship between resilience and the tendency to substance abuse (P<0.05). There was a significant and positive relationship between academic procrastination and the tendency to substance abuse (P<0.05) in the study samples. Academic resilience and procrastination could explain 54% of the variance in substance abuse tendency in the investigated adolescents. Resiliency (-0.556) and academic procrastination (-0.436) played a significant role in predicting the tendency of substance abuse in adolescents.
Conclusion: Academic resilience and procrastination predicted a tendency for substance abuse in secondary school students. Therefore, these risk factors need to be considered in preventive measures and interventions for this age group.
Yalda Mirmoeini, Hamid Sarlak, Shima Normohammadi, Afrooz Nakhostin, Zohreh Salimi,
Volume 23, Issue 2 (5-2020)
Abstract
Background and Aim: Parental acceptance is an important parameter in selecting the proper behavior management technique during pediatric dental treatment. The present study aimed to compare the effects of different informing methods on acceptance of parents about behavior management techniques used in pediatric dentistry.
Methods & Materials: This quasi-experimental study was conducted on one 162 parents of 3-7-year-old uncooperative children who were candidates for dental treatment. They were randomly divided into three groups. Their acceptance about six behavior management techniques including general anesthesia, voice control, hand-over-mouth, parental separation, active and passive physical restraint were assessed by a questionnaire. After determining the level of acceptance, the information about the techniques was presented through three ways include writing, verbal and visual methods. Finally, their acceptance of each technique and the reasons for non-acceptance were re-evaluated. Data were analyzed in SPSS v.23 software using ANOVA and t-test.
Ethical Considerations: This study obtained its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences under code: IR.ARAKMU.REC.1398.102.
Results: The informing methods significantly increased the parents’ acceptance about behavior management techniques. According to the ANOVA results, the effect of visual presentation method in general anesthesia technique was significantly lower than that of other methods (P<0.05), while its effect in active physical restraint technique was significantly greater than that of other methods (P<0.05). There was no statistically significant difference between the effects of informing methods in other behavior management techniques.
Conclusion: Informing parents about pediatric behavior management techniques increase their acceptance. Informing by visual presentation is the most effective method for increasing their acceptance of physical restraint technique, while in their acceptance of general anesthesia technique other informing methods are more effective
Azadeh Safari, Mehdi Moradi, Mojtaba Khansooz,
Volume 23, Issue 2 (5-2020)
Abstract
Background and Aim: The purpose of this study was to investigate the effect of eight weeks of aerobic exercise and the consumption of kefir dough on anthropometric indices, plasma lipid profile and blood pressure in overweight non-athletic women.
Methods & Materials: This quasi-experimental study was performed on 32 non-athletic women with overweight in Arak, Iran (mean age= 33.94±8.58 years, mean height= 1.59±0.05 cm, mean weight= 70.15±6.88 kg, and body mass index= 27.35±1.50 kg/m2) who were voluntarily selected and randomly divided into four groups of 8 (control, exercise, exercise + supplement, and supplement). The control group had a normal diet without exercise; the supplement group received 100 ml kefir dough three meals a day for 8 weeks; the exercise group performed aerobic exercise for 8 weeks, 3 sessions per week, each for 50 minutes. The exercise + supplement group received both aerobic exercise and kefir dough. Blood and anthropometric variables were measured at the beginning and at the end of the intervention. Paired t-test was used to examine the within-group variations and one-way ANOVA to examine the between-group variations. All statistical tests were performed at the significant level of P<0.05.
Ethical Considerations: This study has obtained its ethical approval from the Research Ethics Committee of Qom University (Code: IR.QOM.REC.1398.01).
Results: The combination of kefir dough supplementation and aerobic exercise significantly reduced the mean blood pressure (P=0.003) and BMI (P=0.03) but had no significant effect on total cholesterol (P=0.27), triglycerides (P=0.61), high-density lipoprotein (P=0.16), low-density lipoprotein (P=0.30) and waist-to-hip ratio (P=0.24).
Conclusion: Overweight women can benefit from the aerobic exercise combined with kefir dough supplementation to reduce their blood pressure and BMI. Further studies are recommended to determine the effect of aerobic exercise and kefir supplementation on serum total cholesterol, triglyceride, low- and high-density lipoproteins, and waist-to-hip ratio.
Kurosh Farhadtoski, Mojtaba Bayani, Hamid Sarlak, Zohreh Salimi,
Volume 23, Issue 2 (5-2020)
Abstract
Background and Aim: Chronic periodontitis is the most prevalent form of periodontitis and it generally considered as a progressive inflammatory disease. Environmental and systemic factors can alter the immune response to biofilm and lead to progressive degenerative disease. Chronic periodontitis is defined as an infectious disease that causes inflammation in the tooth-supporting tissues, periodontal attachment loss, and bone loss. Identification of risk factors for this disease is important. Hence, this study aims to evaluate the risk factors for chronic periodontitis.
Methods & Materials: This case-control study was conducted on 120 periodontitis patients and 120 healthy controls in Arak, Iran. A questionnaire was used to estimate their Socio-Economic Status (SES) and survey demographic and risk factors. For the diagnosis of chronic periodontitis, the identification of plaque accumulation site and clinical examination were performed. To investigate the association of chronic periodontitis with study variables, multilevel logistic regression analysis was used in STATA V. 11 software.
Ethical Considerations: This study obtained its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences under code: 1397.145.
Results: The Odds Ratio (OR) of chronic periodontitis in adults aged above 30 years was 2.91 (95% CI: 1.01-8.73). Compared to subjects with low SES, the OR of chronic periodontitis was 2.28 (95% CI: 1.22- 4.27) in those with moderate SES and 0.89 (95% CI: 0.79-0.98) in those with high SES. Compared to patients who did not brush their teeth, the OR of chronic periodontitis was 0.67 (95% CI: 0.39-0.89) in patients reported toothbrushing. Compared to those who reported changing toothbrush sooner than 3 months, the OR was 4.96 (95% CI: 2.27-11.3) in those their changed their toothbrush for more than 6 months interval. The OR of chronic periodontitis in current smokers was 3.09 (95% CI: 1.52-4.76).
Conclusion: Cigarette smoking, alcohol consumption, tooth brushing, and SES are the risk factors associated with chronic periodontitis.
Touhid Khanvari, Faramarz Sardari, Babak Rezaei,
Volume 23, Issue 3 (8-2020)
Abstract
Background and Aim: Exercise aerobic is associated with increased creatine kinase and blood lactate immediately after exercise, leading to increased muscle damage and undesirable changes in many cellular markers including serum creatine kinase. In such situations, consuming nutrients and supplements such as coenzyme Q10 may prevent metabolic stress damage by increasing buffering power. However, comprehensive studies have not been performed on the effects of this nutrient on the index of muscle injury and fatigue caused by exercise.
Methods & Materials: For this purpose, 20 inactive volunteer men were randomly divided into two groups of 10-person Coenzyme Q10 supplement (2.5 mg/kg body weight) and quasi-drug (2.5 mg/kg body weight Dextrose). All subjects participated in the Bruce test exercise contract after 14 days of supplementation. Blood sampling was performed in four stages including baseline, after supplementation, immediately after exercise and two hours after exercise. Creatine kinase, lactate and cortisol indices of both groups were measured during these four stages. Data were analyzed by means of standard deviation and repeated measures ANOVA, Bonferroni post hoc and Independent T-test using SPSS V. 17 at the significant level of 0.05.
Ethical Considerations: This article has been approved by the ethics committee of Tabriz School of Medical Sciences with the ethics code IRCT 201203104663N8.
Results: The results showed that 14 days of Coenzyme Q10 supplementation had a significant effect on cortisol level (P<0.05). In addition, one session of exhausting aerobic activity increased creatinine kinase and lactate (P<0.05). On the other hand, creatinine kinase did not differ significantly after exercise (P>0.05).
Conclusion: According to the results of the present study, 14-day supplementation of Coenzyme Q10 may reduce the cellular damage induced by exhaustive aerobic activity in inactive men and prevent an increase in blood lactate levels.
Mohammadreza Zarali, Zaher Etemad, Kamal Azizbeigi, Pouran Karimi,
Volume 23, Issue 3 (8-2020)
Abstract
Background and Aim Apoptosis or programmed death is active biological process and reversible that the balance between growth and cell death in various tissues, particularly myocardial tissue is essential role. The aim of this study was the effect of 8 weeks High Intensity Interval Training (HIIT) with and without food restriction on gene expression of Caspase 3 and 9 in rats.
Methods & Materials: This study was experimental multi group design with control group which conducted on 30 rats with two months old male. Subjects were divided in to five homogenous groups including base control, control, caloric restriction, interval exercise training and caloric restriction+interval exercise training. Training groups five sessions in weeks were participated in interval exercise training for 8 weeks. The level of gene expression of the proteins Caspase 3 and 9 was evaluated by Real Time-PCR. Dates were analyzed using the 1-way ANOVA at the level of (P<0.05).
Ethical Considerations: The protocol of this study was approved by the Medical Committee of Sanandaj University of Medical Sciences (Code: IR.MYK.REC.1397.5022).
Results: The results showed that the training group had a significant decrease in gene expression of Caspase 3 in comparison with caloric restriction+exercise training (P<0.05). Also, exercise training and exercise training+caloric restriction significantly decrease in the gene expression of Caspase 9 compared to caloric restriction, base control and control (P<0.05) and significantly decrease in the gene expression of Caspase 3 compared to base control and control (P<0.05).
Conclusion: According to the results, it seems that high intensity interval training with and without calorie restriction provides the necessary adaptations to inhibit or stop apoptosis induced by aerobic exercise.
Shahnaz Shahrjerdi,
Volume 23, Issue 3 (8-2020)
Abstract
Background and Aim: Hypertension is a common disease and universal that can cause cardiovascular disease and kidney damage. The purpose of this study was to determine the effect of an eight-weeks massage on blood pressure (systolic and diastolic), heart rate and C-reactive protein in women with hypertension.
Methods & Materials: In this quasi-experimental study, 44 volunteer women with Mean±SD age of 42.12±5.31years were selected from women referred to Arak Oil Company specialized polyclinic with hypertension. Four women excluded from the study for some reason, and the rest were divided into experimental and control groups. In massage group massage was done for three sessions per week, 45-60 minutes in each session, on the back and upper limbs for eight weeks. Data analysis was conducted using dependent and independent t-test by SPSS V. 25 statistical software at the significant level of (P≤0.05).
Ethical Considerations: This study (Code: 92-160-26) was approved in Research Ethics Committee of Arak University of Medical Sciences.
Results: The results showed that eight weeks of massage reduced blood pressure (P=0.001), the heart rate (P=0.001), and C-reactive protein (P=0.001) in women with hypertension compared to the control group (P=0.62).
Conclusion: The findings of this study showed that massage for eight weeks is an efficient and appropriate method to improve systolic and diastolic blood pressure, heart rate, and C-reactive protein in patients with hypertension.
Mohammad Jamalian, Mohsen Eslamdost, Ali Rezaee, Shabanali Alizadeh,
Volume 23, Issue 3 (8-2020)
Abstract
Background and Aim: The deaths caused by traffic accidents are one of the three leading causes of death in Iran. Considering that all deaths from traffic accidents in the forensic organization are undergoing autopsy and also in the treatment centers under oral autopsies, the cause of death is determined, we determined that the cause of reported death from oral autopsy and medical autopsy Compare the law.
Methods & Materials: In this descriptive study, patients who were admitted to the forensic medical center during the year 1395 admitted to the Vali-e-Asr Hospital in Arak, were referred. The causes of death in Vali-asr Hospital were evaluated and compared with the outcome of the forensic oral hearing.
Ethical Considerations: This study ethcally approved by the ethics committee of the Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1395.226).
Results: In this study, 109 patients (1.33%) died from a total of 8153 patients with traffic accidents referred to Valiasr hospital in Arak. Of these, 68.8% were male and 31.2% were women. The Mean±SD age of the patients died was 44.03±22.43 years. Also, 59.6% of the dead died during the first 24 hours of the accident. The most common cause of death, according to the results of oral autopsy, was “multiple injuries,” accounting for 49.5% of the patients in 45 patients.
Conclusion: Abundance of deaths among patients with road traffic accidents and they referred to Valiasr hospital, which was 1.33%. According to the existing standards and considering that the mortality rate in this center is less than 1.5%. It seems that the level of service delivery in this center is favorable.
Seyede Faezeh Fazelian, Ali Mohammadzadeh, Homa Zarinkub, Alireza Akbarzadeh Baghban,
Volume 23, Issue 3 (8-2020)
Abstract
Background and Aim: Lip reading is extraction of speech data from the activity of the lower part of face, particularly jaws, lips, tongue, and teeth that is a natural skill in people with hearing loss. The main purpose of lip reading is to increase the independence of people with hearing loss. Looking at the speakers facial movements significantly increase the ability to understand the spoken words, particularly in the environments where noise is present. In fact this reflects the important role of visual signals. In current study we consider the effects of education on lip reading ability by planning and instructing a lip reading program in male subjects.
Methods & Materials: Sara lip reading test 1 and 2 were used for the assessment of lip reading skills and for studying the effects of lip reading training on recognition of speech. This intervention as a semi-experimental study, was conducted on 27 male students, selected by available sampling. For data analysis, statistical analysis of variance with repeated measurements and Mcnemar was used.
Ethical Considerations: This research with the code IR.SBMU.REC.1394.144 has been approved by the ethics committee of Shahid Beheshti University of Medical Sciences.
Results: There were significant differences between Sara lip reading test 1 scores in 2 positions (P=0.000).Lip reading test scores also showed significant differences in Sara lip reading test 2 in 2 positions (P=0.000). Also between the scores of Consonant-vowel, consonant-vowel syllables, in the position before teaching lip-reading and then ,was significant difference (P<0.05).
Conclusion: The findings of this study showed that instructing lip reading has a positive effect on lip-reading ability in people.
Mahboubeh Sheikhan, Mohammad Reza Kordi, Hamid Rajabi,
Volume 23, Issue 4 (9-2020)
Abstract
Background and Aim: Several microRNAs are involved in regulating muscle mass, which plays an essential role in hypertrophy and atrophy of skeletal muscle, The present study examined the expression of some genes as regulators of muscular atrophy following a period of inertia in rats.
Methods & Materials: For this purpose, 18 male Sprague-Dawley rats were divided into three groups (Control, Exercise+inactivity, and Inactivity). The exercise+inactivity group run on the treadmill for 18 weeks and five times per week. The hindlimb of the animal was immobilized for seven days with the casting method. Soleus muscle was extracted and the expression of the genes was measured by the RT-PCR method. Univariate ANOVA and Tukey post hoc test was used to determine the differences (α=0.05).
Ethical Considerations: The Ethics Committee of the Tehran University of Medical Sciences Research approved this study (Code: IR.SUMS.REC.1396.S 463).
Results: Results showed that immobilization in both Exercise+ inactivity and inactivity groups, compare to the control group, increased expression of miR-1 genes (P<0.10), FOXO3a (P<0.001) and decreased expression of miR-206 (P<0.007) and IGF-1 (P<0.001). This difference was statistically significant.
Conclusion: According to the results of this study, it can be said that changes in the expression of RNAs by chromatography cause changes in the expression of muscle regulating genes, and although endurance exercises have protective effects, they cannot prevent these changes.
Masoumeh Khodadoust, Masoumeh Habibian,
Volume 23, Issue 6 (11-2020)
Abstract
Background and Aim: Weight gain and vitamin D deficiency are associated with increased systemic inflammation and chronic diseases. The current study aimed to investigate the effects of regular Pilates training associated with Vitamin D intake on Tumor Necrosis Factor-α (TNF-α) and Interleukin-10 (IL-10) levels in overweight males.
Methods & Materials: This quasi-experimental study was conducted on 52 overweight men aged 45-55 years. Volunteers were firstly selected through the convenience sampling method. Then, they were divided into Pilates training, Pilates training + vitamin D supplementation, vitamin D supplementation (combined), and control groups (n=13/group). The provided Pilates training program was performed for 8 weeks (with the intensity of 50%-75% of reserve heart rate, 3 sessions/week). The supplement and combined groups also received 50000 units of oral vitamin D weekly for 8 weeks. The serum levels of variables were determined using the ELISA method. The obtained data were analyzed by Paired Samples t-test, one-way Analysis of Variance (ANOVA), and Kruskal–Wallis test at the significant level of <0.05.
Ethical Considerations: This study was approved by the Research Ethics Committee at Islamic Azad University, Babol Branch, Iran (Code: IR.IAU.BABOL.REC.1398.088). Also, this study was approved by the Iranian Clinical Trial Registration Center (Code: IRCT20190831044650N2)
Results: The collected results indicated that 8 weeks of Pilates training, vitamin D intake, and the combined intervention were associated with a significant increase in IL-10 (P<0.001) and a decrease in TNF-α (P<0.001). Additionally, the presented combination intervention was associated with further alternations in the research variables, compared to the other two interventions; however, in the exercise group, the decrease in TNF-α level was more than that in the vitamin D intake group (P=0.012).
Conclusion: It seems that in overweight combined with vitamin D deficiency stats, the anti-inflammatory effects of Pilates training, vitamin D supplementation interventions, and a combination of the two methods can be attributed in part to up-regulation IL-10 and TNF-α reduction; however, the effectiveness of the combined intervention on the development of inflammation was greater than that of the other two interventions. Furthermore, the effect of Pilates training on reducing TNF-α was stronger than that of vitamin D supplementation.
Zahra Zarimoghadam, Hosein Davoodi, Khalil Ghafari, Hamidreza Jamilian,
Volume 24, Issue 1 (3-2021)
Abstract
Background and Aim: The development of any society depends on the educational system of that society. The educational system can be efficient and successful when considering the academic performance of learners in different courses. This study aimed to investigate the effects of mental self-care education on students’ mental health and academic motivation.
Methods & Materials: This was a quasi-experimental study with unequal control and experimental groups. The statistical population of this study was students referring to school counseling centers; 40 of them (n=20/group) were selected by random sampling method. The Depression, Anxiety, and Stress Scale - 21 Items (DASS-21), and Academic Performance Rating Scale were used to collect the necessary data. Psychological self-care training was presented to the experimental group in ten 2-hour sessions. Then, a posttest was conducted on the study groups. Data analysis was performed using Multivariate Analysis of Covariance (MANCOVA).
Ethical Considerations: This article was approved by the Ethics Committee of the Islamic Azad University, Khomeini Branch (Code: IR.IAU.ARAK.REC.1399.001).
Results: The obtained findings indicated that mental self-care education was effective on students’ mental health (P<0.05). Furthermore, psychological self-care education was ineffective on students’ academic motivation.
Conclusion: Mental self-care education was used to improve mental health; however, this training did not affect academic motivation in the examined subjects.
Mohammad Ranjbarian, Korosh Etemad, Fatemeh Zarei, Rozita Farhadi, Jalaledin Sa´di,
Volume 24, Issue 1 (3-2021)
Abstract
Background and Aim: It is almost impossible to imagine life without electromagnetic waves. Such waves play a key role in the function of melatonin and create numerous diseases.
Methods & Materials: This descriptive-analytical study was conducted on 230 kV substations in Golestan Province, Iran in 2016. In total, 44 workers of electrical substations (the case group) and 23 workers of healthcare centers (the control group) with 24-hour shift works were enrolled in this study.
Ethical Considerations: This study was approved by the Ethics Committee of Shahid Beheshti University Medical Sciences( Code: IR.SBMU.THNS.REC.1395.9).
Results: The obtained data suggested that 100% of the electric field intensity and the magnetic flux density measured at the substations were within the permissible range of occupational exposure. The mean level of melatonin in the case group was lower than that in the control group; however, no significant difference was observed in this regard (P=0.761). Additionally, there was no significant difference between melatonin level and age (P=0.381), work experience (P=0.213), job groups (P=0.515), and employee activity area (P=0.482).
Conclusion: According to this study, no significant relationship was observed between electromagnetic waves and melatonin levels. Moreover, electromagnetic waves were within the permissible exposure. Thus, electromagnetic waves did not affect the level of melatonin hormone in male employees of 230 kV substations in Golestan Province. However, there was a decrease in the case group, compared to the controls. Therefore, definite comments require further investigation.
Javad Vakili, Vahid Sari Sarraf, Towhid Khanvari,
Volume 24, Issue 1 (3-2021)
Abstract
Background and Aim: Obesity is a clinical condition that affects the growth-related hormonal system, especially in adolescents. High-Intensity Intermittent Training (HIIT) might reduce such destructive effects.
Methods & Materials: In this quasi-experimental research, among adolescent boys [age: 13-18 years, height: 154±8 cm, Body Mass Index (BMI): 27.05±1.4 kg/m²], 30 volunteer subjects were selected. The study participants were divided into 3 groups of short-term and long-term periodic exercises as well as controls. The short-term exercise group performed 9 bouts of 30 seconds with 150-second breaks between sessions; the long-term exercise group performed 4 bouts of 150 seconds with 240-second breaks between sessions 3 times a week for 8 weeks. Body composition and blood samples were obtained 48 hours before and after conducting the training protocol to measure the desired parameters. The changes of each index were analyzed by repeated-measures Analysis of Variance (ANOVA) at the significant level of P<0.05.
Ethical Considerations: This study was approved by the Ethics Committee of Tabriz University (Code: IR.TABRIZU.REC.1398.021).
Results: After 8 weeks of HIIT, growth hormone increased and thigh, arm circumference, and fat percentages decreased (P<0.05). However, no changes were detected in the insulin-like growth factor I, BMI, and weight of the examined subjects (P>0.05).
Conclusion: Short- and long-term HIIT have the potential to improve the growth hormone status and body composition of overweight adolescents.
Soheila Zolfaghari, Omid Moradi, Hamzeh Ahmadian, Narges Shams Alizadeh,
Volume 24, Issue 2 (5-2021)
Abstract
Background and Aim: The quality of sexual satisfaction of couples plays an essential role in marital dissatisfaction; therefore, sexual satisfaction training can be effective in reducing this marital problem. The present study aimed to investigate the effects of sexual satisfaction model training on reducing couples’ distress among couples referring to counseling centers.
Methods & Materials: This was a quasi-experimental study with pretest-posttest and a control group design. The statistical population of the study included all couples referring to counseling centers in Sanandaj City, in the academic year of 2019-2020. The instruments used in this research were Couple Burnout Measure (CBM). After selecting the sample and randomly forming two groups of 30 experimental and control groups, a pretest was conducted on the study groups. The researcher provided eight 90-minutes training sessions to the experimental group as a model of sexual satisfaction. The obtained data were analyzed using SPSS.
Ethical Considerations: This study was approved by Ethics Committee of Kurdistan University of Medical Sciences (Code: IR.MUK.REC.1397.5037).
Results: The current research results revealed a significant difference (P≤0.001) between the experimental and control groups concerning marital boredom (F=35.581) and its dimensions, including physical fatigue (F=25.074), emotional exhaustion (F=39.031), and mental exhaustion (F=35.020); the effect of the educational program was equal to 0.42, 0.31, 0.41, and 0.39, respectively.
Conclusion: The present study findings indicated that sex education model training was effective in reducing couples’ referrals to counseling centers.
Sahar Dehghani, Leila Rouhi, Noosha Ziya Jahromi, Reza Dehghani, Khalil Khashei Varnamkhasti,
Volume 24, Issue 2 (5-2021)
Abstract
Background and Aim: Proliferate potential differentiate into different cell lineages and high self-renewal of Mesenchymal Stem Cells (MSCs); thus, they are ideal tools for regenerative medicine. However, a leading problem is an oxidative stress in the target tissue and the apoptosis of transplanted stem cells before tissue repair. The pretreatment of stem cells with antioxidants may make them resistant to oxidative stress. Ginger is the main medicinal plant with antioxidant properties. This study explored the antioxidant effects of ginger extract on bioavailability and oxidative stress-induced apoptosis in human adipose tissue-derived mesenchymal stem cells and rat bone marrow examined.
Methods & Materials: In this study, human adipose tissue-derived mesenchymal stem cells and rat bone marrow were cultured in a DMEM medium with 20% FBS. The explored cells were incubated for 4 and 6 hours for pretreatment with different concentrations of ginger extract (50, 100, 200, & 400 mg/mL); then, they were treated with 200 μM H2O2 for 2 hours. Bioavailability was analyzed by ELISA reader using an MTS kit and apoptosis was analyzed by flow cytometry using an Annexin V-FITC/PI kit into the manufacturer’s protocol at both times. The obtained data were analyzed by Analysis of Variance (ANOVA) using SPSS.
Ethical Considerations: This study was approved by the Ethics Research Committee of Shahrekord Branch, Islamic Azad University (Code: IR.IAU.SHK.REC.1397.028).
Results: The MTS results indicated a dose- and time-dependent manner increase in the bioavailability of human adipose tissue-derived mesenchymal treated stem cells. Ginger extract treatment also dose- and time-dependently decreased the rate of apoptosis in rat bone marrow mesenchymal stem cells.
Conclusion: Ginger extract, by reducing the oxidative stress in mesenchymal stem cells, elevates their lifespan in the target tissue, and increases the efficiency of these cells in tissue regeneration.
Ali Asghar Ghalenoei, Hossein Ansari, Abolfazl Payandeh, Azizollah Arbabi Sarjou, Gholamreza Soleimani, Ali Meshkinian,
Volume 24, Issue 3 (8-2021)
Abstract
Background and Aim: Genetic and environmental factors are known to be related to the development of childhood Eczema. We aimed to assess the ecological factors associated with the prevalence of Eczema among children using the ISAAC questionnaire.
Methods & Materials: A total of 1600 primary school girls and boys were selected and examined by multistage random sampling in this cross-sectional study. Data were collected and completed using the International ISAAC Questionnaire, including demographic questions and risk factors through interviews with parents, especially the student’s mother. The data were analyzed in SPSS v. 19 software using the Chi-square test and multiple logistic regression.
Ethical Considerations: This study was approved by the Ethics Committee of Zahedan University of Medical Sciences (Code: REC.1397.481).
Results: The prevalence of current Eczema was 10.4% (95%CI: 8.9-11.9). Co-morbidity with Asthma and Rhinitis was 82.8% and 74.5%, respectively. In multiple logistic regression models, history of allergies in family members (OR: 2.35, 95%CI: 1.53-3.59), father snoring (OR: 3.00, CI95%: 1.98-4.55), Keeping any animal in (OR: 1.6, 95%CI: 1.002-2.58), family size (OR: 0.85, 95%CI: 0.68-0.95), exposure to tobacco smoke at home (OR: 2.84, 95%CI: 1.18-6.81), showed a significant relationship with the occurrence of students’ Eczema.
Conclusion: Exposure to tobacco smoke at home, keeping any animal at home are effective factors in the prevalence of Eczema in children. By eliminating these factors, the prevalence of this disease can be reduced. However, the mothers have the most crucial role in screening and early diagnosis of Eczema in school children regarding determinants in this study. According to the results of this study, it is suggested that parents’ education, especially mothers, be emphasized by paying attention to these favorable factors.
Fateme Dehghani Yunarti, Vazgen Minasian,
Volume 24, Issue 3 (8-2021)
Abstract
Background and Aim: This study aimed to investigate the effect of exercise timing on elevated postprandial glucose and after brief interval exercises in women with obesity.
Methods & Materials: Ten women with obesity (Mean±SD age = 40.41±3.97 years; weight = 86.66±7.26 kg; and BMI = 33.22±2.20 kg/m2) participated in a crossover design exercise intervention: 1) postprandial aerobic exercise, 2) pre-prandial aerobic exercise, 3) brief periodic exercise, and 4) control. Pre- and postprandial exercise included 30 min of moderate-intensity walking on the treadmill before and after each main meal (1 minute of exercise -30 seconds rest). The brief periodic exercise had three one-minute reps of activity every 30 min for 20 times during the day. Twelve-hour continuous glucose monitoring and two-hour postprandial glucose levels were calculated to examine changes in blood glucose levels.
Ethical Considerations: This study was approved by the institutional review board of the University of Isfahan (Ethics Code: IR.UI.REC.1397.119) and conducted in agreement with the ethical principles for biomedical research involving human subjects outlined in the declaration of Helsinki.
Results: The findings of this study suggested that brief periodic exercise resulted in a significant decrease in continuous glucose monitoring levels and postprandial glucose compared to the control group as well as pre-prandial exercise (P˂0.05). However, pre- and postprandial exercise did not result in significant changes in continuous glucose monitoring (P˃0.05). In addition, postprandial exercise led to a significant decrease in postprandial glucose compared to the control group (P˂0.05).
Conclusion: It seems that brief periodic exercise can have more beneficial effects on postprandial glucose levels, probably due to improved glucose metabolism in skeletal muscle.
