Showing 70 results for Mohamad
Narges Aliniya, Alireza Elmieh, Mohamadreza Fadaei Chafy,
Volume 23, Issue 1 (April & May 2020)
Abstract
Background and Aim: Non-alcoholic fatty liver disease is a type of accumulation of fat in the liver cells. Moreover, portulaca oleracea has hypolipidemic properties. Accordingly, the present study aimed to investigate the effect of a combination of training and portulaca oleracea supplementation on plasma lipid profile and liver ultrasound in obese women with nonalcoholic fatty liver.
Methods & Materials: The study population consisted of 40 to 60-year-old obese women with non-alcoholic fatty liver disease. In total, 40 obese women with nonalcoholic fatty liver disease were randomly selected and divided into 4 groups. The study groups included training (n=10), training + supplementation (n=10), placebo (n=10) and supplementation (n=10). Before and after the intervention, sonography of the liver and blood tests were performed. The Paired Samples t-test and Analysis of Variance (ANOVA) were used to analyze the obtained data. The significance level was set at P<0.05.
Ethical Considerations: This study was approved by the Research Ethics Committee of Islamic Azad University, Rasht Branch, Iran (code: IR. IAU.RASHT.REC. 1397. 034). Moreover, it was registered at the Iranian Registry of Clinical Trials (IRCT) (code: IRCT201903090429871).
Results: The obtained data suggested that 12 weeks of portulaca oleracea supplementation and combination training significantly decreased the plasma concentrations of cholesterol (P=0.001), triglyceride (P=0.00), LDL (P=0.00), and significantly increased serum HDL levels (P=0.00) in the exercise + supplement, supplement, and exercise groups (P<0.05). Liver ultrasound data also improved in the exercise + supplement (P=0.02), and exercise (P=0.00) groups.
Conclusion: Portulaca oleracea supplementation with combination exercises could be effective in reducing plasma lipids and improving liver ultrasound in obese women with nonalcoholic fatty liver.
Rahil Mirzaei, Mehdi Javad Chavosh, Mehdi Rajabnia, Valiollah Arash, Ali Bijiani, Maysam Mirzaie, Mohamad Mehdi Naghibi Sistani,
Volume 24, Issue 1 (April & May 2021)
Abstract
Background and Aim: There exists increased demineralization risk of enamel adjacent to fixed orthodontic attachments by cariogenic bacterias (e.g., Streptpcoccus mutans, Streptpcoccus sobrinus) and inadequate data about commonly used orthodontic cements. Thus, we evaluated the antibacterial effects of three common domestic and foreign orthodontic cements (Glass ionomer, Zinc phosphate, & polycarboxylate) on two cariogenic pathogens (S. mutans & S. sobrinus).
Methods & Materials: In this laboratory study, after culturing two standard strains of Streptococcus mutans and Subrinus bacteria and concentrating and diluting them, a direct contact test was used to evaluate the antibacterial properties of types of cement. The study groups (n=5) included the following: three types of glass ionomer resilience cement, Hoffman’s zinc phosphate and Hoffman’s polycarboxylate, and three glass ionomer cement, zinc phosphate, and carboxylate from Aria Dent factory in Iran. The acquired data were analyzed using SPSS v. 17.
Ethical Considerations: The present study was approved by Babol University of Medical Sciences (Code: MUBABOL.REC.1391.7).Results: In both types of culture media, containing Streptococcus mutans and Streptococcus subrinus bacteria, there was a significant difference between culture media containing 3 groups of cements respecting bacterial growth inhibition zone (P<0.001). In general, The mean diameter of the inhibition zone was greater in Iranian polycarboxylate, compared to its foreign counterpart (P<0.001).
Results: Regarding to zone of inhibition, there was statistically significant difference between three tested cements in both S.mutans and S.sobrinus culturing media (P<0.001). The mean diameter of inhibition zone was greater for Iranian polycarboxylate compared to its foreign counterpart (P<0.001).
Conclusion: Glass ionomer cement demonstrated better antibacterial effect compared to zinc phosphate and polycarboxylate cements. There was also greater antibacterial effect of three tested cements on S.sobrinus than S.mutans. Iranian polycarboxylate showed stronger inhibition on both mentioned bacterias compared to the foreign one.
Mohamadreza Arab, Abdolreza Yavari, Marzieh Babaee, Farhad Fatehi,
Volume 24, Issue 6 (February & March 2022)
Abstract
Background and Aim: Swallowing disorder is a common and constant problem in people with Down Syndrome. In experimental method electromyography can be used to evaluate Mastication . The aim of this study was to evaluate the electromyography of the masseter and temporal muscles during Mastication in 2 to 12 years old children with Down syndrome in Arak.
Material and methods: This is a descriptive-analytical and case-control study, that conducted with the purpose of electromyographic study of masseter and temporal muscles during Mastication on 15 children from available 2 to 12 years old Down Syndrome and 15 children that were matched according the method of person-to-person matching in terms of age and gender with samples with Down syndrome
Ethical considerations: In this study, conscious consent was obtained from all parents and no physical harm was inflicted on individuals.
Findings: About the comparison of the mean of amplitude (intensity) of electrical signal of muscle between two groups except right temporal muscle during Mastication and about the mean of the mean frequency when Mastication except for left temporal muscle, in other cases the difference was significant. In the case of comparing the median frequency of the electrical signal of the muscle in most muscles the difference was not significant.
Conclusion: Mean amplitude (intensity) and frequency of the mean electrical signal of the muscle when chewing in most muscles was different between the two groups with Down syndrome and normal, but the differences in mean median frequency in most muscles were insignificant.
Ms Nafise Mohamadi Farsani, Doctor Ebrahim Nasiri Formi, Ms Zohre Khodadadi Jahromi,
Volume 25, Issue 4 (October & November 2022)
Abstract
Introduction: The period of the epidemic of covid-19 is a critical situation where the operating room personnel are in the front line and are in more contact with the sick patient and his respiratory tract. The purpose of this study is to determine the preventive behaviors of operating room personnel of Isfahan teaching hospitals during the epidemic of Covid-19.
Methods: In this cross-sectional descriptive study, 100 operating room personnel of Isfahan teaching hospitals were investigated in 2019-1400. The required information was collected with the help of demographic information questionnaires and a standard questionnaire of specific questions related to preventive behaviors. Data collection was done from March 1999 to June 1400, then it was analyzed by SPSS statistical software. The Research Ethics Committee of Sari University of Medical Sciences has registered this study with the code IR.MAZUMS.REC.1400.115.
Results: The average rate of compliance with preventive behaviors among operating room personnel was 64.53%, which was above the average level. The highest compliance rate was preventive behaviors after the patient with corona virus left the operating room (84.50%). In this research, 100 health care personnel of operating rooms participated in the study. The gender of the majority of them (74%) was female and 63% of them were under 30 years of age. The participants stated that after the patient with corona virus leaves the operating room, they often or always dispose of the patient's consumables correctly (85%), complete disinfection. It was done with detergents (87%), using UV rays (86%), storing and transporting samples in special double-layered containers and fully complying with hygiene principles (83%).
Conclusions: The results showed that at the time of admission of the patient without Covid 19, contraceptive protocols were observed to a lesser extent than when the patient with Covid was admitted. Preventive behaviors and staff knowledge and awareness about the proper use of personal protective equipment can play an effective role in reducing their incidence.
Fatemeh Salabi, Mahsa Lari Baghal, A Rahman Kordzangene, Ali Mohamadian,
Volume 26, Issue 3 (August & September 2023)
Abstract
Introduction: The scorpion of Androctonus crassicauda belongs to the Buthidae family, it has a strong and deadly venom for humans, and every year there are cases of death due to the sting of this scorpion. The purpose of this study is the biological evaluation of the venom of this scorpion, the production of monovalent antivenom against it, and the evaluation of the effectiveness of the produced antivenom.
Methods: The A. crassicauda scorpions were collected from different cities of Khuzestan province and milked by electric shock. In this research, the amount of venom protein, lethal dose 50 (LD50), immune response of horses, purification of antibodies, effectiveness of antivenom (ED50), degree of neutralization of venom with antivenom and the effect of monovalan antivenom in neutralizing the activity of hyaluronidase enzyme were evaluated. This research has been approved by the Ethics Committee of the Razi Vaccine and Serum Research Institute with code IR.RVSRI.REC.1401.017.
Results: The amount of protein and LD50 of the venom from studied scorpion were calculated to be 78 mg/ml and 11.27 µg per mouse, respectively. The results of measuring the antibody titer at different times of venom injection showed the increase in the immune response of horses against the venom. The value of ED50 was around 9 LD50 and 92.22 µg per mouse. According to the results, scorpion venom has hyaluronidase enzyme activity, and 10 µL of the produced pure antivenom was able to neutralize 100% of the venom's hyaluronidase activity.
Conclusions: In this project, extracted venom and produced antivenom showed their effectiveness. The produced antivenom was able to neutralize the venom in mice and prevented the death of the envenomed mice.
Ensiyeh Abbaspour Naderi, Mohammad Ali Bepouei, Mahzad Diar, Matin Mohamadi, Mohammad Hedayati, Mahdi Shahriarinour,
Volume 26, Issue 4 (October & November 2023)
Abstract
Introduction: Urinary tract infection (UTI) is one of the most important and common infections in children. The aim of this study was to investigate the frequency of qnrB and qnrS genes in Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections of children in 17 Shahrivar Hospital in Rasht.
Materials and methods: In this descriptive cross-sectional study, 49 strains of Escherichia coli and Klebsiella pneumoniae were isolated from 17 Shahrivar Hospital in Rasht and identified using biochemical methods. Sensitivity and resistance of strains to antibiotics were determined by Kirby Bohr and dilution broth methods. PCR method was used to evaluate the frequency of qnrS and qnrB genes in isolates.
Results: In this study, the highest resistance was observed in piperacillin (81.5%) and cefazolin (88.9%) isolates from Escherichia coli and in Klebsiella pneumoniae (cefazolin (90.9%) and amoxicillin (95.5%) isolates from 49 Isolated, 73.4% had qnrB gene and 97.9% had qnrS gene.
Conclusion: It seems that one of the reasons for increasing multidrug resistance in hospital isolates of urinary tract infection (UTI) in Rasht is the increased transfer of plasmid genes between these isolates.
Ali Jadidi, Soleiman Zand, Mr Ali Khanmohamadi Hezave, Negin Hosseini,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: Quality of life is one of the most influential issues that can encourage a person to continue a happy and healthy life. On the other hand, spiritual health is one of the dimensions of health and a sense of harmonious connection between oneself, others, nature, and beyond, and leads to understanding the ultimate purpose and meaning in life. The purpose is to determine the relationship between spiritual health and quality of life in university students in Arak. The results of this study can be used to formulate strategic plans improve spiritual health and the quality of students' lives.
Methods: First, the population of each university in Arak city was measured, and taking into account their population and establishing a ratio between the sample size of the study and the population of each university, people who had the characteristics of entering the study were included in the study. The sample size was 400 people and was conducted on students who have been studying at the university for at least six months. After obtaining the consent of the participants, the researchers filled out the questionnaire through interviews with the students. The questionnaires included two instruments: a spiritual health questionnaire and a quality of life questionnaire with 36 questions.
Results: No significant relationship was observed between spiritual health and demographic variables. Likewise, spiritual health had no statistically significant relationship with demographic variables. The analysis of the study data showed that there is a positive correlation between the quality of life and spiritual health of students. (P < 0.05).
Conclusions: According to the horoscope results, there is a relationship between the quality of life and the spiritual health of the students of Arak universities. By improving the quality of students' lives, we can increase their spiritual health, and even by increasing their spiritual health, we can witness the improvement of students' quality of life.
Alireza Rezaie Ashtiani, Ali Jadidi, Ali Khanmohammadi Hazaveh, Seyed Mohamad Aghae Pour,
Volume 27, Issue 4 (10-2024)
Abstract
Introduction: One of the clinical manifestations of coronavirus is neurological symptoms. However, due to the emergence of this virus, little information is available about its symptoms. Therefore, this study aimed to evaluate the prevalence of neurological symptoms in patients with coronavirus at hospitals in Arak.
Methods: In this study, all patients hospitalized with COVID-19 in two hospitals in Arak who were willing to participate were selected by census. The questionnaires consisted of two parts: demographic information and the prevalence and severity of neurological symptoms, which were completed by interviews with patients.
Results: 208 patients with a mean age of 60.5±14.1 years participated in the study. Of the 20 neurological symptoms studied, only two (tingling around the mouth and cranial nerve palsy) were absent in patients. The most common neurological symptoms in patients were headache (82.5%), fatigue (81%) and muscle pain (74.9%), respectively. Also, according to the visual scale, participants reported the highest severity for headache (average: 7.5), followed by fatigue (average: 7.03), and muscle weakness (average: 6.9).
Conclusions: The results showed that the most common neurological symptoms in patients with coronary heart disease include headache, fatigue, and muscle pain and the most severe neurological symptoms in these patients are headache, fatigue, and muscle weakness. According to the findings of this study, these results can be used to diagnose patients and follow them up.
Atefeh Khaki, Maryam Baazm, Mohamad Bayat,
Volume 27, Issue 5 (12-2024)
Abstract
Introduction: Glyphosate is the most popular broad-spectrum herbicide globally due to the growing demand for glyphosate-resistant crops. Glyphosate exhibits harmful properties, including cytotoxicity, neurotoxicity, and reproductive toxicity. This study aimed to investigate the detrimental effects of glyphosate on ovarian histopathology in mice and the in vitro maturation (IVM) of oocytes following superovulation.
Methods: In this study, thirty-two female NMRI mice were randomly divided into the following groups: control, glyphosate, superovulation, and superovulation-glyphosate. Animals received glyphosate (0.5%) continuously through drinking water for three weeks. HMG and HCG were used to induce superovulation. Oocytes were collected from the ampulla, and the quantity and quality of oocytes were analyzed. Then, in vitro maturation (IVM) of oocytes was performed. At the end of the study, ovarian histopathology was analyzed.
Results: Compared to the control group, the glyphosate-treated group exhibited a significant decrease in secondary and Graafian follicles while demonstrating a concomitant increase in atretic follicles (P < 0.05). Additionally, the superovulation-glyphosate group showed fewer germinal vesicle breakdown (GVBD) and MII oocytes than the superovulation group. In the superovulation-glyphosate group, there was a notable reduction in GVBD and MII oocytes following in vitro maturation (IVM).
Conclusions: Glyphosate has the potential to damage ovarian tissue and adversely affect IVM and oogenesis.
Davoud Shamsi, Dr Mohsen Mohammadian, Dr Khalil Ali Mohamadzadeh, Dr Azadeh Ashrafi,
Volume 28, Issue 2 (4-2025)
Abstract
Good governance, as one of the fundamental concepts in managing health systems, plays a critical role in improving efficiency, effectiveness, and equity in delivering healthcare services. Emphasizing principles such as transparency, accountability, participation, and rule of law, good governance has been regarded as a framework for enhancing policymaking and management within health systems.
Objective: This study aimed to design and propose a model of good governance in the health system using a combined approach of thematic analysis and the partial least squares (PLS) method.
Methodology: The research employed both qualitative and quantitative methods. In the qualitative phase, the research population consisted of managers, experts in health and medical sciences, senior officials from the Ministry of Health and Medical Education, and academic scholars. Seventeen participants were selected using purposive and snowball sampling methods until theoretical saturation was achieved. In the quantitative phase, the PLS method was utilized to fit the proposed model. The statistical population included all health and medical professionals in Iran. Based on Cochran’s formula, the minimum sample size was calculated to be 384 participants.
Findings: The results of thematic analysis in the qualitative phase, followed by model fitting in the quantitative phase, revealed that the final model of good governance in the health system consists of seven main dimensions: effectiveness, efficiency, equity, transparency and accountability, participation, rule of law, and leadership. Each dimension was further divided into specific components, confirming their significance in strengthening good governance.
Conclusion: This study presents a comprehensive model of good governance for the health system, offering a framework to enhance policymaking, management, and performance in this field. The proposed model can serve as a tool for strategic decision-making and improving managerial structures.