Showing 124 results for Zahra
Mohammad Parastesh, Zahra Yousefvand, Behzad Aria, Majid Mardaniyan Ghahfarrokh, Jamileh Ahmadi,
Volume 28, Issue 3 (8-2025)
Abstract
Introduction: Cisplatin, a widely used chemotherapy agent, offers therapeutic benefits for cancer treatment but often leads to adverse effects on neurogenesis and oxidative stress. On the other hand, physical activity has been proposed as a potential strategy to counteract these side effects. Therefore, the aim of the present study was to investigate the effect of an endurance training period on oxidative stress markers in the brain tissue of rats induced with cisplatin.
Methods: In this study, 32 male rats with an average weight of 220 grams were divided into four groups: healthy control, cisplatin-injected control, endurance training, and cisplatin + endurance training. After 8 weeks of endurance training, the rats were dissected, and blood serum was separated to measure oxidant and antioxidant factors. Additionally, the brain was removed under sterile conditions for the examination of the desired markers. Data were analyzed using one-way ANOVA.
Results: The results showed that cisplatin significantly decreased MDA and significantly increased TAC and CAT in the cisplatin-receiving control group. On the other hand, 8 weeks of endurance training significantly decreased MDA and significantly increased TAC and CAT. Moreover, no significant change was observed in serum SOD levels. In brain tissue, MDA levels significantly increased, and TAC, CAT, and SOD levels significantly decreased in the cisplatin-receiving group. Conversely, 8 weeks of endurance training reduced MDA levels and increased TAC, CAT, and SOD levels.
Conclusions: Based on the findings of the present study, it appears that physical exercise has protective effects against cisplatin-induced oxidative stress in the brain, which may be attributed to its antioxidant capabilities
Mehtab Farahani, Fatemeh Mehrabi, Mohammad Ali Mardom, Abdollah Abolfathi, Zahra Borzabadi Farahani, Fatemeh Rafiei,
Volume 28, Issue 4 (10-2025)
Abstract
Introduction: The purpose of this study was to investigate the effect of education based on the self-efficacy model on coping strategies and hope in breast cancer patients undergoing chemotherapy.
Methods: This study was conducted on 62 breast cancer patients undergoing chemotherapy. The intervention group received four training sessions on chemotherapy side effects and management strategies based on the self-efficacy model, while the control group received routine care without additional training. Demographic questionnaires, the Billings and Moss Coping Skills Questionnaire, and the Schneider Hope Scale were completed by both groups immediately before and after the intervention. Data were analyzed using appropriate statistical tests.
Results: The average hope in the intervention and control groups was low before and after the intervention. It remained low in the control group but showed a significant increase in the intervention group (P < 0.05). Statistical tests showed that there is a significant relationship between the average total life expectancy and their age, economy and education (P<0.05). Before the intervention, both groups demonstrated low use of coping strategies. After the educational intervention, the control group maintained low usage while, the intervention group showed substantially increased use of coping strategies.
Conclusions: Self-efficacy training intervention increased life expectancy and coping strategies in breast cancer patients undergoing chemotherapy.
Hana Asadi, Hossien Ghamari Givi, Zahra Akhavi Samarien,
Volume 28, Issue 5 (12-2025)
Abstract
Introduction: This study aims to examine the psychological experiences of adolescent girls coping with Premenstrual Syndrome (PMS) and analyze its psychological, emotional, and social effects on their quality of life. Understanding how PMS influences various aspects of adolescent girls' lives, including academic performance, social relationships, and emotional well-being, is essential for developing appropriate interventions.
Methods: This qualitative study employed a phenomenological approach. A total of 18 adolescent girls, aged 14-18, who had experienced PMS at least once, participated in the study. Participants were selected using purposive sampling. Data were collected through semi-structured interviews, and Colaizzi’s seven-step method was used to analyze the data.
Results: The findings of the study revealed four main themes and twelve sub-themes. The psychological impacts included reduced concentration, difficulty in logical decision-making, and mental fatigue. In the emotional domain, participants reported feelings of depression, anxiety, irritability, and mood swings. The social impacts involved Social Withdrawal, concealment of symptoms, and reduced interaction with family members. Additionally, participants used coping strategies such as relaxation techniques, stress management, and seeking social support to manage their symptoms.
Conclusions: The results of this study showed that premenstrual syndrome (PMS) has significant psychological, emotional, and social effects on the lives of adolescent girls. Participants reported experiences such as decreased concentration, anxiety, emotional instability, social withdrawal, and efforts to hide their symptoms. Moreover, coping strategies like stress management, mental relaxation, and receiving social support played an important role in helping them deal with their condition. A deeper understanding of these adolescents’ lived experiences can serve as a foundation for awareness-raising efforts, psychosocial support, and educational policy-making within schools and families.
Najmeh Hejazi, Farid Zand, Seyed Jalil Masoomi, Marzieh Akbarzadeh, Zahra Sohrabi, Zahra Moosavi Shirazifard,
Volume 28, Issue 6 (1-2026)
Abstract
Introduction: The aim of the present study was to investigate the relationship between the nutritional status of patients with different methods on the day of admission and dietary intake during the stay with the ICU mortality rate.
Methods: In this prospective cohort study, 125 patients were studied from admission to discharge in eight ICUs. At the time of admission, the nutritional status of the patients was assessed using the SGA questionnaire, anthropometric measurements, biochemical indices, body composition markers and the assessment of Organ Function Impairment (SOFA) and Severity of Illness (APPACHE) scores. The prescribed and received diet of the patients during their stay was recorded. By recording the mortality cases of this unit, the factors related to the mortality were also determined.
Results: Based on the SGA questionnaire, the rate of malnutrition on the day of admission was 28.8% and 29.6% of patients died during their stay in the intensive care unit. It was also found that a one-unit increase in serum IL-6 level and SOFA score at admission increased the risk of death during the stay in the ward by 1.008 and 1.14, respectively (P=0.003 and P=0.01), and with a one-gram increase in protein intake, the risk of death during the stay in the ward decreased by 8% (P<0.001).
Conclusions: This study showed that serum interleukin-6 level and SOFA score at the time of admission and the amount of protein intake during the stay in the ward affect the mortality rate in the ICU patients.
