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Introduction: Extracts of leaves from Camellia sinensis L contains polyphenolic components with antimicrobial activity. In this investigation biofilm inhibitory effects of black and green tea extracts were defined for five members of enterobacteriacea family including: Enteropathogenic Escherichia coli, Shigella flexneri, Proteus mirabilis, Klebsiella pneumoniae and Salmonella enterica serovar Typhimurium. Because tea is the most widely drunk beverage in Iran, therefore investigation of its effects on enterobacterial biofilm formation and colonization is very important. Materials and Methods: In this experimental study after extraction of samples with Soxhlet extractor in water/ methanol solution, further extraction took place in Ethyl acetate phase. The extracts preserved in 4oC refrigerator after sterilization by 0.44 µ filters. Well diffusion (Kirby Bauer) and broth dilution methods were used for evaluation of minimum inhibitory concentration of biofilm formation in black and green tea extracts treated cultures. Evaluation of biofilm formation was assayed by observation of colony forming unit of cultured bacteria per milliliter by sampling from Erlenmeyer flask wall scratching onto Tripticase soy agar medium and comparing the results with controls. Analysis of data was done using analysis of variance. Results: Biofilm inhibitory effects of black tea were greater than green tea. The concentration of 4.5 mg/ml of black tea and 5mg/ml of green tea had bactericidal effects against examined bacteria. On Mueller Hinton agar, Proteus mirabilis was more sensitive to black tea EPEC was more sensitive to green tea and Klebsiella pneumoniae showed more resistance to both extracts. Conclusion: Due to the fact that gastrointestinal tract is directly affected with consumed beverage, the high concentration of tea entered in lumen can reduce the number of enterobacteriaceae and can reduce their carcinogenic amine products. Thus it plays an important role in inhibition of gastrointestinal lymphoma and colon carcinoma. Also application of tea polyphenols as a food preservative can be useful.

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Introduction: Delivery of immediate medical interventions appropriate to the severity of clinical status of patients is a main public expectation of emergency departments. Waiting time and length of stay are the key measures to asses the quality of care in emergency departments. This study is done to investigate the waiting time and length of stay of attendants to emergency department of Vali-e-Asr Hospital, Arak-Iran. Materials and Methods: This analytical cross-sectional research was conducted in a general emergency department of a teaching hospital in Arak to asses the waiting time and length of stay of patients. In the first stage of the study all attendants during a 6 weeks period were classified regarding to the severity of their clinical status by an educated nurse and a general practitioner using a three category scale (guideline) presented by ministry of Health and Medical Education (2001). Also waiting time for a general practitioner visit was measured and documented by the resident general practitioner. In the second stage, a sample of 100 documents of patients in group 1 and 2 admitted for specialist visit were assessed for the waiting time and length of stay in emergency department. Mean of waiting time according to patients clinical status and the specialty of the first physician were analyzed by t-test and ANOVA (p =0.05). Results: During a 6 weeks period, of 1963 patients, 179(9.1%) were categorized as emergent (category 1), 391(19.9%) urgent (category 2) and 1393 (71%) non urgent. The mean waiting time for general practitioner visit was 5 minutes. The median and mean of waiting time for specialist visit in group 1 and 2 of patients were 225 and 262±156, 220 and 227±153 minutes, respectively. The median and mean of length of stay was 1 and 2 days, respectively. No differences were found between waiting time of various specialties visit in patients of categories 1 and 2. Conclusion: Regarding the long waiting time for specialist visit, using triage in emergency departments is necessary. This needs planning and organization for the presence of specialists in the hospital, over the time. Also regarding the large number of nonurgent patients, 24 hours presence of a general practitioner is necessary.

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Introduction: Based on statistical and epidemiological studies, cancer is the third most common cause of death after heart diseases and accidents, therefore planning to control cancer is essential for public health. Cancer registration is an important part of cancer control, and the collected data could be useful in etiological studies, and health programming to prevent and treat the disease. In this study cancer incidence and cancer registration in Markazi province investigated. Materials and Methods: In this descriptive study, data related to cancer were collected from the health center of Markazi province, from 2001 to 2006. Then the prevalence and incidence of different kind of cancer were determined. Results: Results showed that the top ten cancers among women were: 1-Breast 2-Skin 3-Stomach 4-Colorectal 5-Lung 6-Uterus 7-Bladder 8-Lymphoma 9-Thyroid 10-Esophagus, and the ten most prevalent cancers among men were: 1-Skin 2-Bladder 3-Stomach 4-Lung 5-Prostate 6-Colon and Colorectal 7-Esophagus 8-Lymphoma 9-Testese 10-Gall bladder. Conclusion: In this investigation we also compared cancer incidence and distribution in Markazi province with national rates and our results showed that in some years, cancer statistics is different from national statistics which it may be due to different environmental and epidemiological factors.

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Introduction: Methicillin resistant staphylococcus aureus strains are the most important agents of nosocomial infections. The conventional antibiotic susceptibility methods such as disk diffusion are not suitable for detection of these strains due to their heteroresistancy. Therefore, in this study, agar screen and duplex-PCR were compared in determination of methicillin resistant Staphylococcus aureus (MRSA) strains isolated from nose of personnel in Hajar hospital of Shahre-kord, 2007. Materials and Methods: In this experimental study a total of 204 nasal swabs from personnel of Hajar hospital over a period of 6 months were collected. The specimens were cultured on mannitol salt agar for primary isolation and identification of Staphylococcus aureus strains and their susceptibility pattern to oxacillin was assessed using agar screen method. Finally, using duplex PCR, the isolates were tested for the presence of mecA gene. Results were compared and sensitivity and specificity of the method was determined. Results: In this study, 23 of the 52 (44%) Staphylococcus aureus isolates were resistant to oxacillin using agar screen method. However, mecA gene was detected in 27 of the 52 strains (52%). Our results showed that the sensitivity and specificity of agar screen method in determination of MRSA strains were 81.5% and 96%, respectively comparing with PCR. Conclusion: Oxacillin agar screen, comparing PCR, is an inexpensive, applied and phenotypical method with low false positive and suitable for screening of MRSA. However, due to its relatively high false negative results is not appropriate for screening of MRSA strains isolated from hospital-employed nasal carriers.

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Introduction: In this study, antimutagenesis effect of ethanolic extract of propolis by Ames test against two mutagenic substances named azide sodium and potassium permanganate in the presence and the absence of microsomal homogenate of mouse liver (S9) has been investigated. Materials and Methods: In this experimental study at first, different concentrations of ethanolic extract of propolis (0.1-5%) for determining minimum inhibitory concentration (MIC) against tester strains were used. Then by Ames test, antimutagenesis effect was assessed in nontoxic extent. In this test, various strains of Salmonella typhymurium (TA100 and TA97) that contained selective mutation in their operon histidine, were used. Mutant strains (His-) were grown on culture media containing minimum salt and glucose in the presence of mutagen substances above. So only those bacteria that were reversed by mutation (His+) could grow and form colonies on culture media. If antimutagen (EEP) and mutagen substances were gathered, reversed mutation would be reduced and the rate of mutation inhibition could be calculated by means of formula. The differences between the averages of revertants per plate of the sample in relation to the mutagens were analyzed using SPSS software and one-way ANOVA. Results: The resulted MIC values clearly showed that ethanolic extract of propolis at 5% concentration has antibacterial activity against Salmonella typhymurium, but in 0.1-4% concentrations, such effects were not seen. Findings also showed that propolis in such concentrations could neutralize mutagenic effects of those substances in a dose dependent manner. Conclusion: Finally we found that ethanolic extract of propolis that contains different kinds of major and important substances like flavonoids, has good antimutagenic effects and the best concentration for obtaining such effect is in 4% which also was confirmed with microsomal results. The mechanism of antibacterial effect of propolis is complex and it has no analogy to any classic antibiotics, but it should be emphasized that bacterial cell division is inhibited by propolis. Some researchers also argue that propolis could inhibit DNA-dependent RNA polymerase.

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Introduction: Typhlitis is a complication in GI tract specially in ileum and cecum due to sever prolonged neutropenia. The syndrome usually occurs in patients with leukaemia who take aggressive chemotherapy or in solid tumor treated with taxane base regimen. The syndrome is accompanied with neutropenia, fever, generalized abdominal pain specially in right lower quadrant and probably a mass in this area. Case: The patient is a 44 year old man which was presented with enlargement of right testes since two months ago. In sonographic evaluation of testes a mass was defined and surgery was done for him, which pathologic result was seminoma. Staging workup was done and in CT Scan a lymph node with size of 35 mm was detected in paracaval area . According to this result the patient received chemotherapy with Cisplatin and Etoposide. One day after completion of chemotherapy he developed abdominal pain , fever and bloody diarrhea and referred to hospital and admitted with diagnosis of typhlitis. Conclusion: Typhlitis is not restricted to a complication of leukaemia treatment or taxane base chemotherapy and other cytotoxic drugs can induce this problem. On the other hand, neutropenia and typhlitis can occur immediately after chemotherapy in sensitive patient and so the time of nadir value of white blood cell is too short.

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Introduction: A pseudoaneurysm is a pulsetile hematoma secondary to bleeding into soft tissue, which involves peripheral vessels in the most cases. A femoral artery pseudoaneurysm that is a rare complication, mainly occurs following prior arterial catheterization but it may also be formed with trauma. In this article a superficial femoral artery is reported. Case: The patient is a 24 years old woman who was admitted with a wound in the posteroinferior region of right tight 10 days before her recent referral. The skin of the wound had been repaired. After 1 week pain, progressing swelling in inferior region of tight and knee, fever, shivering and limping were presented. In physical examination, 90 degree flexion of knee, edema, warmth and tenderness in inferior region of tight were observed. Any pulse of dorsalis-pedis and posterior-tibialis was not touched. In the next step blood laboratory test, simple X-ray, Doppler sonography and magnetic resonance imaging (MRI) of right lower limb were accomplished. Finally, with the diagnosis of femoral artery pseudoaneurysm, excision of the pseudoaneurysm with reverse saphenous vein grafting was performed. Conclusion: Pseudoaneurysm should be noticed in patients with history of penetrating trauma and symptoms due to infection. In these cases sonography is necessary to get the exact diagnosis. The size of aneurysm and patient’s symptoms, determine the method of treatment.

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Background: In molecular diagnosis of microbial agent, purification of chromosome is very important step. In this study, after cell destruction, DNA replication was done by increasing the denaturation time, without DNA purification. Methods and Materials: In this experimental study eight different dilution of E.coli (8/100, 4/100, 2/100, 1/100, 1/200, 1/400, 1/800 and 1/1600) solution were madce in D.W, Bacteria were separated by filtration. Polymerase chain reaction method was used to propagate 162 rRNA gene by design primers without DNA Purification. In order to confirme sensitivity of PCR, contamination of 15 different sources of Arak well water wafer was compared by MPN method. For confirmed sensitivity of PCR, 15 sources of water in Arak were examined and compared with MPN method. Results: Present of bacteria in diution sou tion were confirmed by culture. Polymerale Chain reaction (PCR) data were shown this method is able to recognize bacteria in above dilutions after filtration. This study showed high sensitivity of PCR method in compare to MPN method. Conclusion: Results were shown without stages of extraction of DNA, PCR were done without losing chromosome. Therefore false negative results were decrease and avoided from difficult phases.

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Background: Marital conflicts have great impact on social, economic and cultural aspects of the couples and their children. New Psychological interventions like “Imago Relationship Therapy” (IRT) have been widely used for resolving these conflicts. This study examined the efficacy of couple dialogue technique on marital relationship and children`s behavior in Iranian society. Methods and Materials: In a Clinical Trial study eighty consecutive couples refered to general pediatric clinics due to their children’s diseases, randomly allocated to intervention group(couple dialogue technique) and control group (consult usual treatment method) in consultation center. They filled "Distance and Isolation Questionnaire" and "Gottmann Love and Respect Scale" at baseline, post treatment and three months after intervention as follow up all of them. General linear Model with Repeated Measurements was used to analyze the data. Results: In this study, scores of mutual love and respect in marital relationship (Gottmann scale) and scores in Flooding, Loneliness and Retreatment subscales of Distance and Isolation Questionnaire had a better condition in IRT group just after the trial (P<0.05) but after three months, the differences between two groups were only marginal significant (P<0.1). In Parallel lives` subscale, scores were decreased in two groups, but right after trial there was not significant scores of the groups did not difference between scores. Scores after three months in IRT group was significantly lower in compare to control group. Scores of CBCL have not statistically significant differences in both groups at any time (P>0.05). Conclusion: This study revealed couple dialogue technique was an effective intervention in solving marital conflicts in Iranian population but had not a significant effect on children’s behavioral profile. This may be due to other factors or insufficient duration of intervention and needs more investigation and needs more investigation.

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Background: pentylenetetrazole Kindling is widely used as a model for epileptogenesis. The achievement of kindling criterion is known to require repeated drug injection during time to develop. In this article a series of experiments aimed to examin the hypothesis that after 4 primary injections only time is needed to induced kindling in wistar rats. Methods and Materials: In this experimental research, 32 male Wistar rats were divided in two groups. Control Group were kindled by repeated injections of pentylenetetrazole (PTZ 37.5 mg/kgi.p. 48 h interval), in case group were done 4 repeated injections of pentylenetetrazole and have 32 days time lapse, at the end of experiment two groups received same dose of PTZ simultaneously and seizure parameters were assessed. Data were analyzed using student’s t-test and one way ANOVA and Turkey’s test. Results: Results showed there isn’t significant differences in seizure parameters such as seizure stage (control 4.75±0.26, case 4.75±0.29), stage 2 latency (control 165±16.6, case 216±38.68), stage 5 latency (control 2.13±0.38, case 3.47±0.64) and stage 5 duration (control 21.15±2.42, case 23.42±1.20) between two groups. Conclusion: Resuits of this experiment introduces the new critical time window for PTZ kindling.

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Background: There has been an increase in the number of women willing to have a caesarean birth because of their fear of childbirth. It seems the childbirth preparation educational class is a good way to remove or alleviate fears associated with pregnancy and childbirth.This research designed to identify the effect of childbirth preparation classes on childbirth fear on the primiparous women. Methods and Materials: The present study is a clinical trial which was carried out in 2007 at Milad Hospital, with 100 nulliparous pregnant women. Childbirth fear was measured by childbirth attitudes questionnaire. Normal pregnant women in the second trimester with childbirth fear score was 28 or more were randomly selected and dirided into experimental and control group with 50 subject in each qroup. The experimental group attended nine childbirth preparation class sessions and control group received routine antennal care. Results: The mean scored fear of childbirth in case and control group were 39.35±6.96 and 40.71±6.23 respectively. There was not significant difference between two groups. After the sessions, comparing childbirth fear score between two groups in third trimester showed the mean score of childbirth fear among experimental group was lower than control group (29.82+/- 7.18 compare to 38.03+/-9.27), and the differences statistically was significant (p<0.001). Mode of delivery was significantly different between the two groups. Conclusion: Primiparous women attended childbirth preparation classes acquired lower score of childbirth fear in compare to women received routine prenatal care. The results of this research showed relaxation training decreased childbirth fear and increased normal vaginal delivery.

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Background: The face the main channel through which the individual communicates. It is the site of beauty and attractiveness. Physical attractiveness has stereotyping nature. Because the precise content of the stereotype depends on cultural values. The aim of this study was described the range of psychosocial issues burned disfigurement people that psychosocial support programmes may need to address after hospitaization. Methods and Materials: Part of data from a larger study grounded theory approach was reported by this Paper. In this qualitative study, individual in depths interview performed with 21 participants. Interviews were analyzed using a content analysis. Results: After data analyzed five axial category emerging from this qualitative study included social behaviors and beliefs (reproach, retirement, wrong thoughts and beliefs, stigmatize, pity) emotional problems (grief, shame, fear of expulsion, aversion, hopelessness) reactions assessment (positive assessment, Negative assessment) strategy (hidden, separation, self-presentation) and weariness. Conclusion: Findings indicated negative behaviors' and beliefs' of people cause emotional problems in disfigured people. Thise persons perform inappropriate strategy against behaviors' and beliefs' of people. Therefore This persons need to appropriate supportive programs for community, family and person instruction to knowledge, attitude and practice promotion.

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Background: Backache is a common problem in pregnancy period . Scientists believe that some simple exercise can help to prevent the occurrence of backache during their pregnancy period. Thus, this research carried out in order to investigate the effect of some simple exercises and correct daily activity in prevention of backache in pregnancy period. Methods and Materials: This is a clinical trial study that was carried out on 138 of pregnant women .The first group including 66 women which considered as control group and treatment group including 72 women. The research had four stages: 1) stage of taking history. 2) Arrange a teaching program. 3) stage of performance( In case group samples were done 60 minutes aerobic exercises for 3 days a week for the 30 weeks undersupervision a physiotherapist). 4) Assessment the results. Data were analyzed by SPSS for statistical analysis. Results: According to the result 18.2% of woman that were under treatment and 36.6% of control group, suffered from backache. Chi-square test showed significant differences between two groups. In addition Odd ratio of treatment population was 2(CI%95 = 4/04-1/91 & p<0/05). Conclusion: The result showed simple exercises during pregnancy period can not eliminate backache, but it can decrease delay backach.

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Background: Breast cancer is the most prevalent type of all cancer in women. In this study form various methods for treatment of depression due cancer. This study conducted for comparison drug therapy and drug-cognitive therapy on decreasing depression, effect of drug and cognitive theray on decreasing depression. Methods and Materials: This is a clinical trial study. Form patient refered to oncology clinic and ward of vali-e-Asr hospital 78 women were selected by simple sampling. Based on Beck depression test, 42 of them had depression. They randomly divided to case and control groups. Both groups received antideresant drug as usual. But case group had also cognitive- drug therapy. Afrer 6 Month treatment both group were tested again for depression. Data was analyzed by spss using independent and paired t tests. Results: The mean depression score hadnot signigiant difference between case and control grops beor and after treatment. The mean depression score in control group had no significant deference before and after treatment the mean depression score in the case group was significantly different after treatment (p<0.05). The mean score of depression in control group was more than case group after treatment. Conclusion: In the present study cognitive therapy cause a significant decrease in depression score of case group.

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Background: Metronidazole has antibacterial and antiparasitic action. Therefore it can use for treatment inflammatory diseases as Crohn. The effect of metronidazole on human’s blood lipids to reducing levels of LDL and VLDL and increasing level of HDL is under investigation. Target of this research is consideration effect of metronidazole on hyperlipidemia case of death such as coronary artry disrase. Methods and Materials: This study is a triple blind clinical trial was done on 100 voluntaries between 25-65 years old. with hyperlipidemia. Samples divided in two equal groups. The first group received metronidazol, 500mg, BID, for 10 days, and control group received placebo with the same dose. Lipids of serum were measured before and after using drugs, then data analyzed by SPSS software. Results: In metronidazol group amount of total cholesterol, LDL and Triglyceride were significantly less than placebo group. HDL’s amount in metronidazole group was significantly more than placebo group. Conclusion: Significant effect of metronidazole on reducing harmful blood lipids and increasing useful blood lipids. It can be suggested a probable candidate in treatment of hyperlipidemia. Maybe it can use with this application. Although it needs to more study by meta analysis to validate this effect.

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Background: One of the best examples of epimorphic regeneration in the mammals is the formation of new tissues formed from blastema in holes punched in the ears of rabbits. The aim of this research is to investigate speed and percentage of regeneration in different geometrical shaped holes and different regions of rabbit's ear. Methods and Materials: In this experimental research different region of rabbit's ear (proximal, medial and distal) were punched as different geometrical shaped holes (circlc, quadrangle and triangle) with the same area (50 mm2) Ubyg a puncher which designed for this purpose. The regeneration of wounds was evaluated and the percentage of regeneration was calculated. After punching, each 3 days (36-40 days). Results: Results showed speed and percentage of regeneration in circular holes was significantly (P<0.05) more than quadrangular and triangular holes. In addition, regeneration speed of holes located in proximal regions of ear, was more than peripheral holes. Conclusion: Wound regeneration in rabbit's ear is related to the geometrical shape of holes. Speed and the percentage of regeneration in circular shapes is more than angular shapes.

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Background: Pain is an unpleasant feeling which humans experience. It is a warning sign of the damaged tissue. Due to the awful sense of pain, scientists always attempt to relieve it. Retinoic acid (RT), an active metabolite of natural vitamin A has important roles in modulation of the inflammatory responses. The aim of the present study was to analyze the pain threshold of rats which had microinjections of RT, applying acute and chronic models. Methods and Materials: In this study, the tail flick and formalin tests were used to determine pain threshold. In each test, the acute and chronic pain thresholds of 252 Wistar male rats (275 ± 25 gr) were assayed. The druge were injected in the acute model one-dose30 minutes before behavioral testing and in chronic model two-dose for one or two-weeks. The rats of both models divided randomly into six groups (n=7). In four treatment groups retinoic acid (RT) intra cerebro ventricular (i.C.V) were injected as dosagc of 0.5, 3 and 6 (µg/kg) micrograms per kilogram. In control group, was microinjected by ACSF. In vehicle group injected RT solvent (DMSO+ Distil water). Results: The resuits Showed acute injection of RT did not change pain thresholds in the tail-flick methd, but the chronic administration of RT (0.5, 1, 3, 6 µg/kg) reduced tail-flick latencies of the rats (p<0.05) in compare to DMSO group. The threshold of pain in the first phase of formalin test was reduced after injection of 3µg/kg of RT for two weeks. Conclusion: It was concluded that chronic i.c.v. injections of RT can induce significant hyperalgesia in rat.

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Background: Epileptic seizures are manifestation of epilepsy. Understanding of the mechanisms causing epileptic disorder needs careful analyses of the electroencephalograph (EEG) records. The detection of epileptic form discharges (spike wave) in the EEG is an important component in the diagnosis of epilepsy. Approximately one in every 100 persons will experience a seizure at some time in their life. Already intelligence spike detection method discucsed but purpose of this research is diagnosis of different kind of epilepsy (grandmal and Petitmal) by design of an intelligence diagnosis processing. Methods and Materials: In this descriptive study, 100 EEG signals of brain hemispheres from different person in healthy, interictal and ictal conditions were used. Fifty Hz noise and artifact signals were removed by soft ware procedure then signals separated by expert neurologist to three categories, healthy (frequency band 8-12 Hz), petitmal seizures (typical 3 Hz), grandmal seizures (clonic stage with 4 Hz frequency) and divided each of them to 6 seconds segments. Information of this signals (background alpha, spike and slow, poly spike and poly sharp) were extracted by wavelet transform and classified by soft ware procedure neural network to there groups healthy, ptitmal and grandmal epilepsy. Results: In designed software accuracy of diagnosis ptitmal and grandmal epilepsies was obtained about 80% Conclusion: This method introduced intelligent diagnosis of epilepsy (ptitmal and gradmal) and automatically detected healthy person from epileptic patients. One of the other advantages is help to neurologist for detection of sickness clearly and expendable different kinds of other epilepsy

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Background: According to the report of Iranian Center of Disease Control, in the summer of 2005 an outbreak of cholera (Inaba serotype) occurred in Iran. The outbreak lasted the mid of September. The aim of this study was to use the result of different studies performed during this period to determine source of infection. Methods and Materials: This is a meta-analysis study, which studies performed in Qum, Arak, Karaj, Golestan and Ghazvin were eligible. All of these studies were case control ones performed during the August 2005. The total of cases were 531. Pooled odds ratios was used to estimate by fixed and random method. All computations were performed by Stata 8 software. Results: The estimated pooled odds ratios resulted from 5 differemt studies were used in the meta-analysis as the following: travelling (1.64 95% CI: 0.98-1.88), non-pasteurized ice cream (0.88 95%CI: 0.48-1.61), post toilet hand washing (3.72 95% CI: 0.86-16.05), eating meal outside home (2.38 95% CI: 1.46-3.90), raw fruit eating (0.98 95% CI: 0.42-2.18) and raw vegetables use (5.36 95%CI: 2.4-12). Conclusion: According to the results of this study raw vegetable use and having meal outside home were significantly associated to the cholera in mentioned provinc

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Background: In the recent years, oxidative stress was attended as one of the causal factors of ischemic stroke. In terms of the role of genetic, geographic and ethnic factors in the prevalence of stroke, This study was designed to compare the oxidative stress indexes of stroke patients with normal healthy subjects in this geographic area. Methods and Materials: In this case-control study, 36 patients older than 50 years with ischemic stroke and 45 healthy subjects with same age and sex, were enrolled. Five milliliter blood were drawn from all subjects. Samples were centrifuged and plasma was separated. Total antioxidant capacity, lipid peroxidation and thiol levels were measured respettively by FRAP, TBA and HU methods. Then the result was analyzed using t-test. Results: Results showed total antioxidant capacity and thiol plasma levels were lower in stroke patients in compare to healthy subjects, but only the thiol group had significant difference(P=0/001). Although lipid peroxidation showed a slight but non-significant difference in stroke patients in compare to control group. Conclusion: These findings suggest oxidative stress in patients with acute ischemic stroke may be conseaqence of an imbalance in oxidant/antioxidant homeostasis. Therefore it may be useful to recommend antioxidant medications or diet for these patients.