Showing 23 results for Ayati
Mrs Elham Mohammadi, Dr Akram Bayati, Dr Sharare Khosravi, Dr Fakhredin Shariat Madari,
Volume 26, Issue 2 (June & July 2023)
Abstract
Introduction: Seizure due to fever is the most prevalent neurological condition in children aged 6 to 60 months. A child's seizure can cause significant distress for parents, particularly the mother. Anxiety control and the well-being of the mother are crucial elements in managing child seizures.
Methods: In this clinical trial, 70 mothers with children experiencing febrile convulsions were divided into two groups: an experimental group and a control group. The division was done using an available sampling method. The mothers in the experimental group received an intervention based on Orem's self-care model, while the mothers in the control group received the usual care. Mothers' anxiety was assessed one day after the child's hospitalization and again three weeks later using the Spielberger questionnaire. The data was analyzed using descriptive statistics, Chi-square test, Fisher's test, and analysis of covariance in SPSS software version 25.
Results: The study showed that after one day of hospitalization, the anxiety score of mothers in the test group was 101.68, compared to 106.25 in the control group. Three weeks later, the test group's anxiety score decreased to 68.97, while the control group's score was 96.34. Importantly, the decrease in the test group was statistically significant compared to the control group (P = 0.000).
Conclusions: Engaging in self-care activities results in a decrease in maternal anxiety. Hence, it is recommended to employ this approach when caring for children who are hospitalized.
Ensiyeh Abbaspour Naderi, Mohammad Ali Bepouei, Mahzad Diar, Matin Mohamadi, Mohammad Hedayati, Mahdi Shahriarinour,
Volume 26, Issue 4 (October & November 2023)
Abstract
Introduction: Urinary tract infection (UTI) is one of the most important and common infections in children. The aim of this study was to investigate the frequency of qnrB and qnrS genes in Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections of children in 17 Shahrivar Hospital in Rasht.
Materials and methods: In this descriptive cross-sectional study, 49 strains of Escherichia coli and Klebsiella pneumoniae were isolated from 17 Shahrivar Hospital in Rasht and identified using biochemical methods. Sensitivity and resistance of strains to antibiotics were determined by Kirby Bohr and dilution broth methods. PCR method was used to evaluate the frequency of qnrS and qnrB genes in isolates.
Results: In this study, the highest resistance was observed in piperacillin (81.5%) and cefazolin (88.9%) isolates from Escherichia coli and in Klebsiella pneumoniae (cefazolin (90.9%) and amoxicillin (95.5%) isolates from 49 Isolated, 73.4% had qnrB gene and 97.9% had qnrS gene.
Conclusion: It seems that one of the reasons for increasing multidrug resistance in hospital isolates of urinary tract infection (UTI) in Rasht is the increased transfer of plasmid genes between these isolates.
Dr. Maryam Arabloei Sani, Dr. Zahra Hajebrahimi, Dr. Parichehreh Yaghmaei, Dr. Nasim Hayati Roodbari,
Volume 26, Issue 5 (December & January 2023)
Abstract
Background and Aim: Diabetes is a type of metabolic disease and one of the most common endocrine diseases. Oxidative stress and inflammation play an important role in the development and progression of diabetes. mTOR signaling pathway play an important role in glucose homeostasis and proliferation of pancreatic beta cells. In the present study, the therapeutic effects of p-cymene on oxidative stress markers and expression of the mTOR gene in diabetic male Wistar rats were investigated.
Materials and Methods: Diabetes was induced by injecting 55 mg/kg body weight of streptozotocin. Biochemical analyses of pancreatic tissue and real-time PCR were done to investigate the effects of metformin (55 mg/kg body weight) and p-cymene (25, 50, and 100 mg/kg body weight) on the activities of catalase and glutathione peroxidase enzymes and mTOR gene expression.
Findings: Streptozotocin decreased catalase and glutathione peroxidase enzymes and decreased the expression of the mTOR gene in pancreatic tissue. Treatment with metformin or p-cymene improved the activities of catalase and glutathione peroxidase enzymes and the expression of the mTOR gene in a dose-independent manner.
Conclusion: Results indicate that p-cymene has antioxidant properties and can regulate the mTOR signaling pathway. Therefore, p-cymene may be effective for the treatment of diabetes alone or in combination with metformin.
