Showing 31 results for jamilian
Neda Saleh Jafari , Farzad Zamanibarsari, Hamidreza Jamilian, Bahman Sadeghi Sede , Hamidreza Zafari,
Volume 19, Issue 7 (10-2016)
Abstract
Background: The definite treatment of indicated Hypertrophy of the tonsils is Tonsillectomy. The aim of this study was to compare the efficacy and necessity of diclofenac suppository and simultaneous prescription of acetaminophen alone in controlling and reducing pain and improving swallowing and satisfaction after surgery for tonsillectomy in children.
Materials and Methods: In this clinical trial, 180 children 7 to 14 years Tvnsykltvmy surgery were enrolled. Patients in an improbable way, easy and were divided into three groups of 60. Immediately after the surgery acetaminophen, diclofenac, or a combination of both was used. The cases of pain in the early hours, seventh, thirteenth and nineteenth after surgery were compared.
Results: There was a significant difference between the average pains of all groups in all hours (p<0.05). There was a significant difference between the groups from the point of view of side effects such as Nausea, Vomiting and Pyrexia (p<0.05), But there was no significant difference between the groups from the point of view of After Surgery Bleeding (p>0.05).
Conclusion: We can say that Rectal Diclofenac is a more effective medication for reducing pain after the Tonsillectomy surgery in contrast with Rectal Acetaminophen or a mixture of the two, which may cause the patients to use less Narcotics after the surgery.
Mehri Jamilian, Zeinab Zolfi,
Volume 19, Issue 8 (11-2016)
Abstract
Abstract
Background: We are aware of no study evaluating the effects of zinc supplementation on metabolic profiles of patients with polycystic ovary syndrome (PCOS). This study was conducted to evaluate the effects of zinc supplementation on glucose homeostasis parameters in PCOS women.
Materials and Methods: This randomized, double-blind, placebo-controlled trial was conducted among 52 women diagnosed with PCOS and aged 18-40 years old. Participants were randomly divided into two groups to receive 220 mg zinc sulfate (containing 50 mg zinc) supplements (n=26) or placebo (n=26) per day for 8 weeks. Fasting blood samples were taken at baseline and after 8 weeks of intervention to quantify glucose and insulin.
Results: After 8 weeks of intervention, zinc-supplemented patients had reduced fasting plasma glucose (FPG) (-4.3±9.6 vs. +0.5±6.0 mg/dL, p=0.03), serum insulin (-3.0 ± 2.9 vs. + 1.5 ± 8.4 µIU/ml, p=0.01), serum triglycerides levels (-15.6±40.3 vs. +14.5±25.3 mg/dL, p=0.002) and a significant increase in insulin sensitivity (+0.02±0.02 vs. -0.004±0.05, p=0.03) compared with the placebo.
Conclusion: Taken together, 220 mg zinc sulfate supplementation per day for 8 weeks among PCOS women had beneficial effects on metabolic profiles.
Mehri Jamilian, Roghayeh Afshar,
Volume 19, Issue 12 (3-2017)
Abstract
Abstract
Background: The efficacy of evening primrose oil has been reported in metabolic syndrome and other diseases.The role of vitamin D has been proposed in the risk reducing of chronic diseases such as obesity, metabolic syndrome and diabetes too. We are aware of no study that examined the effects of evening primrose oil and vitamin D supplementation on metabolic profiles in gestational diabetes (GDM). This study was designed to assess the effects of evening primrose oil and vitamin D supplementation on metabolic profiles among pregnant women with GDM.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was performed among 60 women with GDM. Subjects were randomly assigned to receive either evening primrose oil and vitamin D supplements (n=30) or placebo (n=30) for 6 weeks. Fasting blood samples were taken at study baseline and after 6 weeks of intervention to quantify biochemical variables.
Results: Evening primrose oil and vitamin D supplementation led to a significant decrease in serum high sensitivity-C reactive protein (hs-CRP ) levels (change from baseline: -1.9±4.0 vs. +0.6±2.6 µg/mL, p=0.006) and MDA (-0.8±2.1 vs. +0.6±1.5 µmol/L,p=0.005) compared with placebo. Furthermore, a significant increase in plasma NO (+2.5±3.8 vs. -1.9±8.1 µmol/L, p=0.009) and TAC levels (+84.4±174.8 vs. -36.4±143.1 mmol/L, p=0.005) was seen after evening primrose oil and vitamin D supplementation compared with placebo.
Conclusion: Evening primrose oil and vitamin D supplementation in GDM women had beneficial effects on metabolic profiles.
Mehri Jamilian, Reyhaneh Sahebkashaf,
Volume 20, Issue 1 (4-2017)
Abstract
Abstract
Background: We are aware of no study examining the effects of Soy supplementation on patients with polycystic ovary syndrome (PCOS).This study was conducted to evaluate the effects of Soy supplementation on metabolic profiles in women with PCOS.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was conducted among 70 women diagnosed with PCOS. Participants were randomly divided into two groups to receive 50 mg Soy isoflavone supplements (n=35) or placebo (n=35) for 12 weeks. Fasting blood samples were taken at baseline and after a 12-week intervention to quantify related factors.
Results: Intervention group, subjects who received Soy supplements had significantly decreased total serum testosterone levels (-0.2±0.4 vs. +0.1±0.3 ng/mL, p=0.01) compared with the placebo. In addition, a significant rise in plasma glutathione (+96.0±102.2 vs. +22.7±157.8 µmol/L, p=0.04) and a significant decrease in malondialdhyde levels (-0.7±0.8 vs. +0.8±2.3, p=0.001) was observed following the consumption of Soy supplements compared with the placebo.
Conclusion: According to this study, Soy supplementation among PCOS women had beneficial effects on metabolic profiles.
Mostafa Jani, Hamidreza Jamilian, Ahmad Aramoon,
Volume 20, Issue 9 (12-2017)
Abstract
Abstract
Background: The purpose of the present research was to compare the perceived stress, self-efficacy and mental health in patients with HIV and Hepatitis C.
Materials and Methods: The method of present research was causal-comparative research. Population included of all patients with acquired immune deficiency syndrome or AIDS referred to a behavioral disease counseling centers of Arak city and all patients of chronic hepatitis caused by the hepatitis C virus referred to Gastroenterology Research Center and private practice of digestive specialists in Arak city. The sample consisted of 200 people, including 100 HIV and 100 people with hepatitis C who participated in the study and were selected for screening. All participants responded to the three instruments including Cohen Perceived Stress, Kamark and Mrimlstyn, Sherer's Self-efficacy and Goldberg general health questionnaires. Data analysis was done in two descriptive and inferential levels using SPSS version 20.
Results: The results of MONOVA showed that two groups were different in the perceived stress, self-efficacy and mental health, physical symptoms, depression, anxiety, social dysfunction, at the level of 0.01.
Conclusion: It is suggested that workshops to be held to careful inform how much stress and self-efficacy had affected on physical and mental health of patients with acquired immune deficiency syndrome or AIDS.
Mehri Jamilian, Jamilian Somayeh Jamshidi,
Volume 20, Issue 10 (1-2018)
Abstract
Abstract
Background: Selenium supplement has multiple important effects, including anti-inflammatory effect. The aim of this study was to assess the effects of selenium supplement on gene expression of inflammatory cytokines and vascular endothelial growth factor in gestational diabetes.
Materials and Methods: This randomized double blind placebo control trial was performed on 40 patients suffering from GDM aged 18–40 years old. Participants were randomly divided into interventional group receiving 200mg/day selenium supplements (n=20) and control group receiving placebo (n=20) for 6 weeks. Primary outcome was gene expression of inflammatory cytokines and VEGF which were assessed in lymphocyte of GDM patients by RT-PCR method.
Results: After 6 weeks intervention, in comparison with the control group, interventional group showed down regulation of gene expression of tumor necrosis factor alpha (TNF–α) (p=0.02) and transforming growth factor beta (TGF–β) (p=0.01) and up-regulation of gene expression of vascular endothelial (VEGF) (p = 0.03) in lymphocytes of GDM. There was not any significant change following intervention with selenium regarding gene expression of interleukin IL-1 β and IL-8 in lymphocytes of GDM patients.
Conclusion: 6 weeks supplementation with selenium in patients with GDM can cause down regulated gene expression of TNF-α and TGF–β, and up regulated gene expression of VEGF. Selenium supplement had not any effect on gene expression of IL-1 β and IL-8.
Mehri Jamilian, Nazanin Ravanbakhsh,
Volume 21, Issue 5 (10-2018)
Abstract
Background and Aim: We are aware of no study that examined the effects of vitamin E plus omega-3 fatty acid supplementation on inflammatory and oxidative stress biomarkers in pregnant women with gestational diabetes (GDM). This study aimed to evaluate the effects of vitamin E plus omega-3 supplementation on insulin metabolism and inflammatory and oxidative stress biomarkers in pregnant women with gestational diabetes.
Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was performed on 60 women with GDM. Subjects were randomly assigned to receive either 400 IU vitamin E plus 1000 mg omega-3 fatty acid supplements (n=30) or placebo (n=30) for 6 weeks. Fasting blood samples were taken at study baseline and after 6 weeks of intervention to quantify biochemical variables.
Findings: Vitamin E plus omega-3 fatty acid supplementation led to a significant rise in plasma total antioxidant capacity (+187.5±224.9 vs. -32.5±136.1 mmol/L, p<0.001) and a significant decrease in MDA levels (-0.1±0.9 vs. +0.6±1.4 µmol/L, p=0.04) compared with placebo. Furthermore, a significant increase in plasma NO levels (+5.0±7.7 vs. -12.0±28.0 µmol/L, p=0.002) was seen after vitamin E plus omega-3 fatty acid supplementation compared with the placebo.
Conclusion: Vitamin E plus omega-3 fatty acid supplementation in GDM women had beneficial effects on biomarkers of inflammation and oxidative stress.
Khadijeh Mohsenpourian, Mostafa Nokani, Hamidreza Jamilian, Mohsen Ghasemi,
Volume 22, Issue 4 (9-2019)
Abstract
Background and Aim Obsessive-Compulsive Disorder (OCD) is the fourth most common psychiatric disorder. It consists of symptoms, including intrusive thoughts, rituals, behaviors, preoccupations, and compulsions. This study aimed to evaluate the effectiveness of attention bias modification and selective serotonin reuptake inhibitors in reducing the symptoms of OCD.
Methods and Materials study population comprised patients with OCD referring to the outpatient clinic of Amir Kabir Hospital in Arak City, Iran. Of them, 80 patients were randomly assigned to the two groups. The first group received the selective serotonin reuptake inhibitors, and the other group received the treatment modality to determine the effectiveness of the Yale-Brown OCD scale and dot-probe task tests.
Ethical Considerations The Research Ethics Committee of Arak University of Medical Sciences approved this study (Research Ethics Code: IR.ARAKMU.REC.1396.284).
Results Treatment of attention bias modification in comparison with selective serotonin reuptake inhibitors did not show a significant difference in the reduction of attention bias (P=0.377). Also, a significant difference between the two groups in reducing the symptoms of OCD (P=0.007), indicates that selective serotonin reuptake inhibitors are more effective in diminishing the symptoms of OCD. Besides the attention bias modification decreased the symptoms of OCD, but these results were not significant (P=0.228)
Conclusion Attention bias modification is a significant improvement in reducing attention bias and can be used with other interventions. However, it appears that the reduction in the severity of OCD symptoms, as against this intervention, continues to be the preferred treatment for pharmacotherapy.
Zahra Zarimoghadam, Hosein Davoodi, Khalil Ghafari, Hamidreza Jamilian,
Volume 24, Issue 1 (April & May 2021)
Abstract
Background and Aim: The development of any society depends on the educational system of that society. The educational system can be efficient and successful when considering the academic performance of learners in different courses. This study aimed to investigate the effects of mental self-care education on students’ mental health and academic motivation.
Methods & Materials: This was a quasi-experimental study with unequal control and experimental groups. The statistical population of this study was students referring to school counseling centers; 40 of them (n=20/group) were selected by random sampling method. The Depression, Anxiety, and Stress Scale - 21 Items (DASS-21), and Academic Performance Rating Scale were used to collect the necessary data. Psychological self-care training was presented to the experimental group in ten 2-hour sessions. Then, a posttest was conducted on the study groups. Data analysis was performed using Multivariate Analysis of Covariance (MANCOVA).
Ethical Considerations: This article was approved by the Ethics Committee of the Islamic Azad University, Khomeini Branch (Code: IR.IAU.ARAK.REC.1399.001).
Results: The obtained findings indicated that mental self-care education was effective on students’ mental health (P<0.05). Furthermore, psychological self-care education was ineffective on students’ academic motivation.
Conclusion: Mental self-care education was used to improve mental health; however, this training did not affect academic motivation in the examined subjects.
Farideh Ranjbaran, Hamid Reza Jamilian, Bahman Sadeghi Sade,
Volume 24, Issue 1 (April & May 2021)
Abstract
Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, with a severe decline in performance, disability, and a 15% risk of suicide. Allopurinol increases the level of tryptophan in the body by inhibiting xanthine oxidase, and by elevating the level of tryptophan, i.e., a precursor to serotonin. Accordingly, it can improve the symptoms of depression. This study aimed to investigate the impact of allopurinol on MDD.
Methods & Materials: In this double-blind clinical trial, 70 patients with MDD, diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition-Third Edition (DSM IV-TR) were randomly (paired & individual patient records) divided into two equal groups. Both research groups received 40 mg of citalopram daily for 6 weeks. In addition to citalopram, the intervention group received 300 mg allopurinol daily and the control group received a placebo. At the end of the third and sixth weeks, the examined patients were tested for Hamilton Depression Rating Scale (HDRS).
Ethical Considerations: This study was approved by the Ethics Committee of the Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1394.68). Also, it was approved by the Iranian Registry of Clinical Trials (Code: IRCT201508277373n6).
Results: The Mean±SD HDRS’s score, after 3 weeks of treatment, in the control and allopurinol groups was measured as 28.42±3.1 and 23.02±3.4, respectively. After 6 weeks after treatment, the Mean±SD depression score in the control and allopurinol groups was equal to 23.28±4.1 and 20.4±1.2, in sequence. A significant difference was observed between the research groups; thus, the intervention group obtained a lower mean score in the HDRS than the controls.
Conclusion: Allopurinol can improve the symptoms of depression and can also be used as an adjunct in the treatment of depression.
Morteza Ghasemi, Hamidreza Jamilian, Mansoureh Nourizadeh Ab-Barik,
Volume 24, Issue 4 (October & November 2021)
Abstract
Background and Aim: The main purpose of this study was to compare the metacognitive beliefs of people with hypochondriasis Covid 19 and normal people.
Methods & Materials: In this research, the causal-comparative method has been used. The statistical population of the study included all people with hypochondriasis disorder Covid 19 in Arak, based on this, 30 people from the population with this disorder and 30 people from the normal population were selected by available sampling method and based on Age and education were matched. Data were collected based on the short form of the 1997 Wells Metacognition Questionnaire (MCQ-30). Multivariate analysis of variance was used to analyze the data.
Ethical Considerations: The present study has been registered with the code IR.IAU.ARAK.REC.1399.036 in the ethics committee of Islamic Azad University Arak branch.
Results: There was a significant difference between metacognitive beliefs in patients with hypochondriasis covid 19 and normal individuals (P<0.001). These patients were significantly different from normal individuals in the components of positive beliefs about worry, negative beliefs about thought control, self-awareness, cognitive uncertainty, and the need to control thoughts. And in the components of positive beliefs about anxiety, negative beliefs. They got higher scores on controlling thoughts and cognitive self but on the components of cognitive uncertainty and the need to control thoughts compared to normal people.
Conclusion: Hypochondriasis disorder causes many problems for the individual and the health system, so by recognizing the dysfunctional metacognitive beliefs of these patients, metacognitive therapy can be an effective treatment for this disorder.
