Farshideh Didgar,
Volume 2, Issue 7 (6-1999)
Abstract
In this report we present a care of cephalic tetanus in a 57-year old man whose onset was accompanied by right facial palsy following injuries to the face. Three days before the appearance of facial palsy, the patient have had a wound on his forhead on the same side and seven days after the injury the parient showed trismus lock jow dysonea dysphagia hoarsness and progressing generalized seizure without disturbance of consciousness as are typical in tetanus. There were no remarkable finding on brain CT or Laboratory data. He was managed as a case of tetanus in I.C.U. The patient was completely cured and he discharged on the 35th day after the onset of right facial palsy.
Mozhgan Hashemieh , Fataneh Kobar Fard ,
Volume 2, Issue 7 (6-1999)
Abstract
This study was performed on 50 thalassemic patients in Arak city in order to assess the incidence of hearing loss among these patients. Evaluation of hearing loss in these patients were done with audiometry tests. The mean age was 10 and 40% of patients were in the range of 5-9 years old, 54% of patients were female and 46% of them were male. M/F ratio was 0.85%. 86% of patients have used Desferal (DFO) , and 14% of them have not used DFO. 14% of patients that have hearing loss, were in DFO user group. Also there is a significant relationship between hearing loss and DFO usage and between duration of DFO usage and hearing loss too. There is no significant relationship between hearing loss and ferritin level Thalassemic patients that use DFO must be assess with serial audiometry tests in order to prevent the effect of ototoxicity of Desferal.
Abdolrahim Sadeghi , Hosein Mozdarani ,
Volume 2, Issue 7 (6-1999)
Abstract
This research is performed to assess clastogenic capacity of cimetidine(CT) against clastogenic effect induced by benzene in terms of micronuclei. For this purpose micronuclei assay method was used. In each experimental group m 5 Balb /C mices was used. 24 hours after i. p .injections slides was prepared from bone marrow and frequency of micronuclei in polychromatic erythrocytes (PCEs) and normochromatic erythrocytes (NCEs) was obtained. Results indicated that CT at therapeutic dose (20mg/kg. b. w) can be reduce genetical damages (micronuclei) due to benzene (1010mg/Kb. B. w) with a dose- related manner (p<0.01, = -0.82). Therefore , our results indicated that CT has anticlastogenic capacity. According to above results and relatively long term use of CT, we suggest using it in the cases in which someone exposed to clastogenic agents such as benzene, especially when someone also suffer from diseases such as peptic ulcer.
Vahid Goharian, Mohammad Sadegh Rajaei, Saeid Sadrnia,
Volume 2, Issue 7 (6-1999)
Abstract
The aim of this study is to determining the prevalence of cigarette smoking and the causes of initiation in boy students of medical science in Arak university. Declining of smoking depends to recognizing risk factors specially in young age group and the results of this study use to evaluate the plans. This descriptive study was done with convenience sampling and studied all boy medical students in Arak university with self-administered questionaires in 77-78 curiculum. This survey instrument contained age, course of study, passed semesters, smoking bahaviour family history, praying and living site .The smoker also answered to question about time of initiation, mean of cost family information and the number who giving up the habit of smikong. 98.7% (n=475) of students with mean of age 23.06 years answered to question 34.3% had smoking bahaviour. The prevalence of smoking was the lowest among those who were married and negative family history. The prevalence of smoking in students who prayed was 1.4 of others. The most common cause of initiation were being resident with friends, stress life and initiation. Lowering we must improve the "NAMAZ" task and marriage accompaniment with lowering stress life and teaching for friend selecting and determining a suitable pattern for students in Arak university.
Mehrangiz Naderi Nabi,
Volume 2, Issue 7 (6-1999)
Abstract
One of the most common psychiatric disorders is depression, that sometimes may be misdiayne because of various presentations, one of these presentations is somatic complaints and patients are referred the different physicans and specialists and received symptomatic therapies. The aim of this study is the determination of prevalence of depression in patients who referred to internal clinic of Hazrat-e-Rasool-e-Akram Hospital. This study was performed between September and march of 1997. All of these patients had various somatic problems for more than two years without any organic findings them the number of patients were one hundered and the assessment was performed by SCL-90-R test. Between these patients , the score of 37 them were about of mean score. Depression was more common low admission groups and also in female. This research shows that depression is one of the best diagnoses in patients with chronic and rewirten somatic complaints which physicans did not find any organic finding in them.
Nemat Billan ,
Volume 2, Issue 8 (9-1999)
Abstract
This research has done for assessment of attitude, practice and knowledge of the internists in medicine faculty in relation to prevalent and nonprevalent diseases of pediatrics involving 10 prevalent and nonprevalent diseases. Results of prevalent emergency diseases:
Index of study =93% good management and trearment ability with supervision of manager = 40%
Follow up = 43%, Reporting=10%
In nonprevalent emergency diseases:
Index of study = 88%, management and treatment ability= 27% good, management and treatment ability with supervision of manager = 47%, Fpllpw up = 26%, Reporting = 3% and in regard to above subjects, scores of education in this department were: prevalent emergency = 36% optimum, 59% acceptable, 5% nonacceptable and nonprevalent emergency=18% optimum, 67% acceptable and 15% nonacceptable.
Mohmoud Soorati, Abbas Bazargani , Elahe Hejazi ,
Volume 2, Issue 8 (9-1999)
Abstract
Present research principal aims was situations determine and effective factors in achievement of Arak medical sciences university students in pre interning test modification, family environment, academic self- concept and learning, s spent time. Statistical social were number 75 from, medical students that only one time had participated in pre interny test. This social was considered by correlation descriptive method, that were data, s collecting instruments one questionaier which constitutes of 29 questions, statistical methods were multiple regression. Results had shown in five of only cognitive entry behaviour predicate present 15 of students academic achievement variance in general test. This sufficient to set in p<0.01 level. But it is nor qualified neither obvious other variable effects. Compound or common effects of principal variables that are part of researches result precent 20 of academic achievement variance of statistical social to account. This sufficient sit on significant p<0.05 level. Results entirely marked enough unability of supposed variables in explaining and predict were studied students academic achievement. So it is doubt variables validity about account and explaining of academic achievement in all of the academid sections and conditions.
Masoume Soufian, Farshideh Didgar,
Volume 2, Issue 8 (9-1999)
Abstract
Cholera is potentially dangerous bacterial infection of the small intestine which may be serious enough to cause death, cholera epidemics cause economical and hygienic problems. In retrospective study, 54 cases were consider during 4 months admitted in Valie -asr hospital. Results were as follow:
There was no significant changes due to sex. Sixty percent of cases were above 50 years. 78% showed vomiting, 11% fever and bloody diarrhea which in half of above cases ameobic dyscentery was observed. In stool examination we observed 32% WBC, 14% RBC and 19% WBC along with RBC. Cell was not seen in 35% of the cases in 5.5% ameobic trophozoite observed. Hypokalemia were observed in 80% acidosis 21% and ATN in 50% which 82% of that resolved after treatment. In all cases with leukocytosis above 20000, ATN have been observed. Rate of ATN and mortality in patients above 50 years significantly increased (4.9) and mortality and time of admission and observing initial symptoms. Due to above results may suggested that, leukolytosis above 20000 may be consider as a prognostic factor in incidence of ATN in above cases, also existence of WBC or RBC in stool smear can not denial eltor.
Zabihollah Shahmoradi,
Volume 2, Issue 9 (3-1999)
Abstract
The ORF disease is transmitted to human from animals such as sheep and goat. Most of the ORF lesions are solitary and appear on the fingers. At the beginning a red macule appears and after one week it is changed to 1-4cm hemorrhagic bullae and after 4-6 weeks complete remission occurs.
In this investigation from 16 patients who are differentiated from other patients, the following information about age, sex, profession, site, number of lesion, previous treatmet, remission period, scar and concomitant skin disease have been collected and the following results have been concluded:
Age distribution of disease has been between 25 to 60 years.
_Sexual distribution is 62.5% in females and 37.5% in male patients.
_Professional distribution is higher 56.25% among housekeepers.
_The most frequent site of involvement in patients was both fingers(75%) and solitary(62.5%)
_Most of the patients (81.25%) recovered without any scar and in 5 cases (31.25%) erythema multiform was seen with ORF.
_Eleven patients (68.75%) has been misdiagnposed and treated as slam tumor, or local infection.
Latif Moeini,
Volume 2, Issue 9 (3-1999)
Abstract
Our study was a descriptive observational and cross sectional research. We studied those asthmatic patients whom referred to Arak Vali-Asr teaching center O.P section during six months from 75/5/1 to 75/8/1 and 75/12/1 to 76/3/1. The number of our patients were around 150. Age of patients: The most age groups are 70-61 years old and 60-51 years old. Sex: 84 men (56%) and 66 women(44%). Residence: 119 urban (79.4%) and 31 rural (20.6%). Age of first attack: maximum number of the Asthmatic patients are between 31-40 years old and minimum are between 11-20 years old (15.3%). Average time of asthmatic attack: The maximum number of asthmatic attacks once per month (32.6%) and minimum once to many times per day(2%). Admition history: -109 patient (72.6%) m admitted for asthma. Time of attack: night (70.6%), day (10.6%) and day and night together (18.6%). Chief complains: dyspnea(72%), wheezing (19.3%), cough (8.6%). The other complains included: cough, wheezing, white color sputum, breathlessness, fever, green color sputum. Risk factors: Allergy: seasonal (92.7%), history of personal allergy (86%), family history of allergy (58.6%), family history of asthma(54%). Drugs: Allergy to asprin and NSAIDE (6%), blocker (2%0).
Mohsen Khaki,
Volume 3, Issue 1 (3-2000)
Abstract
Various gastrointestinal viruses among infected and sensitive people are transmitted through fecal-oral. In some cases according to the type of virus and host conditions, they can cause gastrointestinal disease such as diarrhea and other infections. In some cases it may cause inflammation in tissues and organs post gastrointestinal infections. In this study feces or rectal swab samples were cultures on Hela cell culture media using specific antisera, and the cultured viruses were identified. The results of this study were showed that neutralization is a very available method in isolation and diagnosis of virus. This method can also be used for identification and isolation of viruses in various clinical samples in the pathological, epidemiological and vaccination studies.
Ali Fani,
Volume 3, Issue 1 (3-2000)
Abstract
A 56 years old female was admitted to our hospital, because of, dyspnea, tachycardia hematemesis and melena. In physical exams she was severely ill, pale, and tachycardia, with decreased breath sounds on the base of right lung, with BP, 100.60, and pulse rate of 120/min. Abdomen was soft In rectal exam streaky fresh blood and melena was observed. Diffuse red populace on face, trunk and oral mucosa were present with recurrent nasal bleeding since last year. In upper GI endoscopy and colonoscopy, diffuse telangectasic lesions in esophagus, stomach, duodenum and entire length of colon and streaky fresh blood in colon were observed, Under conservative treatment her bleeding stopped on the 10th day after treatment. Collagen vascular diseases, coagulopathy and malignancies were ruled out by paraclinical examinations. Senile angiodisplastic diseases which are usually limited to colon and vascular ectasia can not be suggested because the skin and upper gastrointestinal tract is involved. Cancers, polyps and hemorrhoid , were ruled out by endoscopy and colonoscopy. Heriditary Hemorrhagic Telangictasia (HHT) is an Auto-Dom disorder with involvement of oral and gastrointestinal mucosa, skin and viscera. HHT involves capillaries, makes tortuous, fragile bloody spaces which can be manifested through infancy to old age. The most common manifestation of the diseases(in addition to nose bleeding and skin lesions), is the severe gastrointestinal bleeding, often leading to massive blood transfusion. Recommended treatment:
1-Coagulotherapy of hemorrhagic lesions. 2- Estrogen and progesterone therapy. 3- Amino caproic acid therapy for prevention of fibrinolysis. 4- In severe cases , surgical therapy is needed.
Hamidreza Nikbin, Jamal Falahati, Ali Akbar Karami,
Volume 3, Issue 1 (3-2000)
Abstract
Tearing is the most important complaints in ophthalmologic patients that one of its reasons is obstruction of lacrimal drainage system. Lacrimal drainage system include superior and inferior punctums that are joined to common canalicule by the superior and inferior canalicule at the medial canthus. Common canalicule leads to lacrimal sac and lacrimal sac is connected by the Nasolacrimal duct to inferior meatus. The most common cause of obstruction is NLD obstruction that in children, it is caused by the failure of canalization of 4 N.L.D (Naso Lacromed ducat). The research has been conducted among 2500 people in Arak city by muitistage sampling. 26 people had lacrimal drainage system disorder. This disorder was observed among all ages but it was mostly among 0-9 and 60-69 age. 18 patients (69.23%) were female and 8 other ones (30.76%)m were male. 21 people (80.76%) had unilateral disorder and 5 (19.23%) patients had bilateral disorder. Among the patients who had unilateral disorder, 11 persons (52.38%) had right side disorder and 10 persons (47.61%) had left side disorder. None of the patients were asymptomatic and all of them had tearing. 22 persons (82%) had obstruction in common cunalicule and one person in punctum.
Ali Fani, Parisa Fani, Mohammad Rafiei, Navid Reza Mashayekhi, Reza Shahmirzaei, Khosro Minavand,
Volume 13, Issue 1 (4-2010)
Abstract
Background: Aspirin (ASA) and helicobacter pylori infection are two major known risk factors for peptic-ulcer. This research aims to examine the interaction between helicobacter pylori and low dose ASA in inducing gastro-intestinal complications. Materials and Methods: The target group consisted of patients with cardiovascular disease who were under low dose ASA therapy. Patients, who had symptoms of dyspepsia, were placed in the case group and those who did not have these symptoms were placed in the control group. 5cc blood samples, required for conducting ELISA Ab., were taken simultaneously in both of the groups. ELISA positive patients underwent UBT test. UBT positive patients were categorized as helicobacter pylori positive and those with negative UBT were placed in the helicobacter pylori negative group. Finally, the ratio of dyspepsia incidence probability to Aspirin usage and helicobacter pylori infection was analyzed. Results: Of the 129 individuals present in the control group and 71 individuals who were in the case group, 72(36%) were UBT positive, and the rest were UBT negative. Of all the patients, 35.5% had dyspepsia and there was a significant difference between UBT positive and UBT negative individuals (p=0.001, OR=6.54). of 43 patients who had signs of intensified dyspepsia 23 persons under went endoscopy assessment which 20 of them were diagnosed with peptic ulcer. Eighty percent of the patients who had developed peptic ulcer, were UBT positive which revealed a significant difference with UBT negative (p=0.001, OR=8.86). Conclusion: In order to reduce gastro-intestinal complications, it is suggested that long term low dose Aspirin takers be subjected for screening and to receive treatment in terms of infection with helicobacter pylori and clinical manifestations.
Kevan Ghasami, Ali Ghazavi, Yahya Jand, Mohamdali Payani, Mahmodreza Khazaei, Ghasem Mosayebi,
Volume 13, Issue 2 (6-2010)
Abstract
Background: Multiple sclerosis (MS) is a chronic, autoimmune disease of the central nervous system (CNS) of unknown etiology. Vitamin D3 (1,25(OH)2D3) has strong immune modulating potential. Nitric Oxide (NO) has been identified as one of the most destructive products of the immune system and is an important factor in demyelination. The effect of short-term vitamin D3 supplementation on NO level was assessed in MS patients. Materials and Methods: The study included 60 MS patients (male and female). Patients were randomized independently, in a double blind design, into one of two treatment groups. Controls (n=30) received current treatment. Vitamin D treated (n=30) individuals received current treatment plus 300000 IU vitamin D3. Vitamin D3 injection was repeated monthly for 6 months. Nitric oxide (NO) production was estimated by Griess reaction. Results: NO levels decreased following vitamin D3 treatment but the differences did not reach significance (12.411.1 μmol/L to 9.88.9 μmol/L). Control group was also associated with an increase in NO levels but not statistically significant (18.417.07 μmol/L to 22.0716.8 μmol/L). Conclusion: Vitamin D3 has not significant effect on the level of nitric oxide. However, further studies should be done to evaluate the potential of vitamin D as an immune modulator in management of MS.
Behrouz Moghaddasi, Zahra Moghadasi, Parvaneh Taheri Nasab,
Volume 13, Issue 2 (6-2010)
Abstract
Introduction: Researches indicates that physical training are a basic component of pulmonary rehabilitation in asthmatic patients , and can result in improvement of sign and symptoms of asthmatic patients.The purpose of present study is evaluation of the effects of physical exercises on pulmonary function and clinical manifestations and signs and symptoms of asthmatic patients.
Materials and methods: The samples included 24 asthmatic patients that participated in a physical exercise program have refered to Ardebil Bou _Ali Hospital (1386) .The researcher followed test –re-test design in the present study.
The data were collected using an asthma clinical manifestations questionnaire and pulmonary function test (Spirometery).
Results: Physical exercises program was effective in improvement pulmonary function of asthmatic patients, and exercises decrease asthmatic signs such as: attacks of wheezing, shortness of breath, chest tightness and coughing.
Conclusion: The results indicate that asthmatic patients would benefit from a physical training and such a physical exercise program can be adapted for use in clinical practice.
Ali Fani, Mohsen Ghasedi, Fatemeh Esmaeeliun, Behrouz Alizadeh,
Volume 13, Issue 3 (9-2010)
Abstract
Background: Irritable bowel syndrome (IBS) which is characterized by chronic abdominal pain and changes in bowel movements is the most common gastrointestinal disease. Curcuma is one of the traditional medications which has been considered in treatment of gastrointestinal diseases. In this study, the effects of curcuma on IBS were investigated. Materials and Methods: In a double-blind randomized study, 140 IBS patients after meeting the inclusion and exclusion criteria, regardless of sex and age and based on internist’s diagnosis, were involved. The patients were randomly divided into case (curcuma) and control (placebo) groups which included 69 and 71 patients, respectively. For converting subjective criteria to objective ones, treatment forms were filled out before the treatment and two and four weeks after the treatment according to visual analog scale. Data were analyzed through descriptive statistics and t-test. Results: Using curcuma and placebo before the treatment and two and four weeks after that improved patients’ clinical symptoms except for vomiting (p=0.001) however, no significant differences were observed in the effectiveness of placebo and curcuma on improvement of clinical symptoms of patients in case and control groups (p>0.05). Conclusion: Using curcuma does not offer any significant differences in controlling and reducing the symptoms of IBS in comparison to the placebo, but its application improves the clinical symptoms of IBS patients.
Fardin Faraji, Afsoon Talaie, Azadeh Saeidi,
Volume 13, Issue 4 (1-2011)
Abstract
Background: Multiple sclerosis (MS) is a demyelinating disease of central nervous system which has different clinical manifestations. Noticing the role of vitamin B12 in synthesis of myelin tissue and the existence of different views about its pathogenesis and causes, we decided to evaluate B12 serum levels in MS patients. Materials and Methods: In a case-control study, 40 patients with definite clinical diagnosis of MS and 80 traumatic patients hospitalized in the emergency ward of Vali-asr Hospital of Arak (the control group) were chosen. The level of blood vitamin B12 was measured for all the subjects through the same type of kit and clinical checklist. Data were analyzed through t-test. Results: The mean vitamin B12 serum level in case and control groups were, respectively, 295±133.3 pg/dl and 257.73±91.3 pg/dl which did not indicate a significant difference(p> 0.05). However, in terms of the type of clinical manifestations, the mean vitamin B12 serum level in MS patients showed at least one sensory, motor, or sphinctery symptom lower than the control group. This difference turned out to be significant(p< 0.05). In terms of MRI findings, patients with brainstem and vertebra plucks respectively had the maximum and minimum vitamin B12 serum levels. Conclusion: Although a significant difference was not observed between the mean vitamin B12 serum levels, based on the significant decreases in the serum levels of this vitamin in some of the patients with subtypes of MS, further studies with larger sample sizes and over longer periods of time are suggested.
Ahmad Neghahi, Hadi Sarafraz, Alireza Shahab Jahanlou, Hamidreza Samimagham,
Volume 14, Issue 2 (5-2011)
Abstract
Background: One of the main complications associated with arteriovenous fistula in hemodialysis patients is the median nerve ischemic neuropathy in the wrist. This study was conducted to examine the effect of arteriovenous fistula on the development of carpal tunnel syndrome.
Materials and Methods: This cross-sectional study was conducted on 37 hemodialysis patients at Shahid Mohammadi Hospital of Bandar Abbas in 2007-2008. All of the patients had either a distal or a proximal arteriovenous fistula in one hand. Nerve conduction velocity and median nerve distal sensory and motor latency were applied to the diagnosis of carpal tunnel syndrome. The limb with fistula (the case) was compared to the one without it. Data were analyzed through independent t-test and Pearson product correlation.
Results: Overall, 17 patients had proximal and the rest had distal fistulas. Fistulas aging more than one year were seen in 15 patients and 22 patients had fistulas less than one year old. Carpal tunnel syndrome had developed in 25 wrists with fistula (17 motor and 8 sensory cases) and 27 wrists without fistula. A significant difference was observed in the median nerve distal sensory latency between the wrists with fistula and those without it. There was not a significant difference between the variables. In addition, there was a significant difference between the age of the fistulas and the incidence of carpal tunnel syndrome.
Conclusion: The rate of the development of carpal tunnel syndrome in wrists with or without fistula is the same. Also, the site of the fistula does not have any effects on the incidence of the median nerve ischemic neuropathy.
Zahra Adgi, Afsaneh Talaei, Mahnaz Mohamadi Kelishadi,
Volume 14, Issue 2 (5-2011)
Abstract
Background: Hirsutism in women is identified as the increasing growth of terminal hair in areas of skin that are sensitive to androgen. The most common causes of hirsutism are PCOS (polycystic ovary syndrome) and idiopathic hirsutism. The role of insulin resistance and hyperinsulinemia as the most important pathogenesis mechanism of PCO is quite obvious, but there is not enough information on the role of insulin resistance in idiopathic hirsutism.
Materials and Methods: This cross-sectional study was conducted on 16 to 40 year old women. Medical history and physical examination were completed for patients with PCOS and idiopathic hirsutism. Hormonal tests and sonography were run for both groups and insulin resistance was assessed using HOMA-IR formula. Data were analyzed using SPSS version. 17.
Results: Mean of serum insulin levels in PCOS and idiopathic hirsutism groups were 16.04±1.4 and 7.32±6.85 µIu/ml, respectively (P<0.001). HOMA-IR values in PCOS and idiopathic hirsutism groups were 3.7± 3.36 and 1.67±1.75, respectively (P< 0.001). Mean of serum DHEA-S levels in PCOS and idiopathic hirsutism groups were 2.48±1 and 1.84±0.46 pg/ml, respectively (P< 0.001). These findings indicated a significant difference between the two groups. However, in terms of serum glucose, testosterone, androstendione, and follicular hormones levels, there were not any significant differences between the two groups.
Conclusion: In both PCOS and idiopathic groups, there was a significant relationship between hirsutism and insulin resistance. This relationship, however, was more significant the PCOS group
