Showing 44 results for Hosseini
Saeed Hajihashemi, Tahereh Jafarian, Mahboobeh Ahmadi, Ali Rahbari, Nasser Hosseini,
Volume 18, Issue 4 (7-2015)
Abstract
Background: Gentamicin is an aminoglycoside antibiotic that broadly is used to treat gram negative bacteria infections, although it has side effects such as nephrotoxicity. According to antioxidant, anti-inflammatory and vasodilatory properties of Zataria Multiflora, the effects of co-treatment with zataria Multiflora and hydroalcholic extract on gentamicin induced nephrotoxicitj were investigated.
Materials and Methods: In this study, male rats of Vistar race were divided into 4 groups: control group, co-treatment with gentamicin and vehicle group, co-treatment with gentamicin and zataria Multifiora extract group, and co-treatment with zataria Multiflora extract and normal saline solution group. Zataria Multiflora hydroalcoholic extract was added to drinking water as 800 PPm concentration. They, systolic blood pressure and renal blood flow (RBF) were measured. Also, the amounts of urea, creatinine, sodium, potassium and osmolarity were measured in plasma and urine samples
Results: In co-treatment group with zataria Multiflora extract, the amounts of urea, creatinine, absolute sodium excretion and relative sodium and potassium excretion and malondialdehyde (MDA) that have been inceased in treatment with gentamicin, significantly were reduced. Creatinine clearance, urine osmolarity, RBF and FRAP that was decreased in gentamicin group in compare to control group, significantly increased.
Conclusion: Co-treatment prevents nephrotoxicity induced by gentamicin and attenuates oxidative-stress associated renal injury by reducing oxygen free radicals and lipid peroxidation, So it can be effective to cure rats receiving gentamicin.
Amir Hossein Hosseini, Leila Kohan, Sara Fallahi,
Volume 18, Issue 8 (11-2015)
Abstract
Background: Obesity is a complex, multifaceted disease resulting from a combination of genetic, environmental, and lifestyle backgrounds, and is associated with increased risk of diseases, such as hypertension, dyslipidemia, and type 2 diabetes. MiRNAs have been reported to be associated with chronic diseases such as obesity. The present study is the first investigation that examines the possible association of rs2910164 polymorphism in mir-146a gene with overweight and obesity in Iranian women.
Materials and Methods: This case-control study was conducted on 133 overweight, 75 obese and 173 healthy control women with normal weight. The rs2910164 polymorphism genotypes of mir-146a gene were determined by the Tetra-ARMS PCR method. Also, logistic regression analysis was used to estimate the association between genotypes and obesity risk.
Results: There was a significant association between GC (OR: 1.8, 95%CI: 1-3.3, p: 0.04) and CC (OR: 4.5, 95%CI: 1.6-12.6, p: 0.004) genotypes with susceptibility to obesity. In the dominant genetic model of the C allele (comparison between CC+GC vs. GG), CC+GC genotypes were associated with the risk of obesity (OR = 2.1, 95% CI: 1.2–3.7, p= 0.01).
Conclusion: This study showed that mir-146a gene rs2910164 polymorphism is associated with obesity risk and the C allele may act as a dominant allele and increase the obesity risk in Iranian women.
.
Majid Askaripour, Syed Reza Fatemi Tabatabaei, Hossein Najafzadehvarzi, Foruzan Hosseini,
Volume 18, Issue 11 (2-2016)
Abstract
Background: Renal injury following ischemia - reperfusion (I/R) is still an unavoidable problem in many remedial and medical situations. Portulaca oleracea (PO) has been known for its anti-oxidative effects. Then, the present study aimed to investigate the effect of ethanolic extract of PO (EEPO) on the renal function and antioxidant status after induction of I/R injury in the rat kidney.
Materials and Methods: A total of 30 rats (Wistar) were divided into five groups (n = 6 each). Sham group: underwent laparotomy without I/R, EEPO group: EEPO administered 300 mg/kg then was operated like sham, I/R group: was underwent renal ischemia/reperfusion only, EEPO150+ I/R and AEPO300+ I/R groups: were administered PO 150 and 300 mg/kg then underwent I/R operation. PO extract was administered for 5 days in the relevant groups by gavage. Serum urea and creatinine (Scr), the level of malondialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH) and total antioxidant activity (TAA) were determined. Data were analyzed by ANOVA and post hoc LSD test. P values of 0.05 or less were considered statistically significant.
Results: Induction of I/R and pretreatment with PO extract, increased the level of superoxide dismutase (SOD) in comparison with sham group (p<0.05, p<0.001). There were no significant differences in the levels of MDA, GSH and TAA among different groups. On the other hand, the Scr and serum urea of the I/R and treated groups were elevated compared to the sham group (p<0.001).
Conclusion: Ethanolic extract of PO did not strongly affect the renal antioxidant status and could not prevent the renal injury following I/R.
Hamid Dalvand, Mehdi Rassafiani, Seyed Ali Hosseini, Seyyed Ali Samadi, Hamid Reza Khankeh,
Volume 18, Issue 12 (3-2016)
Abstract
Background: Mothering handling plays an important role in the daily life of children with cerebral palsy (CP) and their mothers, so that the greatest amount of handling of children with CP is done by the mothers at home. The study aimed to explore the process of mothering handling in the children with CP at home.
Materials and Methods: This qualitative study was conducted using grounded theory methodology in Tehran. The purposeful sampling followed by theoretical sampling. Selecting participants continued to achieve theoretical saturation. The number of participants was 26 including 15 caregivers, 3 children with cerebral palsy, 5 occupational therapists, 1 physiotherapist, and 3 rehabilitation manegers. The main source for gathering data was in-depth, semi-structured interviews. Data were analyzed by Corbin & Straus method (2008).
Results: Six categories/themes emerged from the data, including: motherly care, confronting with unusual co-occupation, confusion in roles, effort to special care, dynamic management of handling, and continuing care. The central category, confrontation with unusual co-occupation, represented the main theme of the research, and all major categories had been related to it.
Conclusion: The results of this research could provide broad perspective to rehabilitation therapists, managers and policy makers for understanding the needs, meeting challenges and concerns of caregivers and children with CP and designing a comprehensive plan for handling process of children with CP and helping them to be empowered for achieving the proper management and effective handling.
Bijan Khademi, Mahboubeh Razmkhah, Ebrahim Eftekhar, Ahmad Hosseini, Hossein Hamedi,
Volume 18, Issue 12 (3-2016)
Abstract
Background: Laryngeal carcinoma induce immune system suppression in tumour micro environments with unknown mechanism. Toll like receptors (TLRs) are important molecules which play a critical role in the management and induction of immune responses. In this regard, the importance and the role of TLR 2, 4 and 9 have not been studied together in laryngeal cancer. The present study aims to evaluate the expression level of TLR2, TLR4 and TLR9 in patients with laryngeal carcinoma.
Materials and Methods: 89 tumour samples and 35 tumour-free tissues were obtained from laryngeal carcinoma male patients and the expression level of TLR2, TLR4 and TLR9 was analysed using Real-time PCR method.
Results: The expression level of TLR2 was increased as the result of increasing lymph node involvement, pretumoral involvement and regional metastasis. Also, the TLR4 gene expression levels were increased 1.5 fold in patients with lymph node involvement. The expression Level of TLR9 was increased by increasing stage and primary tumour involvement. The expression pattern of TLR2 and TLR4 in tumour and tumour-free tissues was the same, while TLR9 gene expressions show higher level in tumour tissues than its normal tissue. None of our findings were statistical significant.
Conclusion: we have shown that the expression status of TLR2, TLR4 and TLR9 in patients with laryngeal cancer was correlated with their clinicopathologic features. Additionally, the expression level of TLRs in cancerous and non-cancerous tissues shows no significant changes.
Seyyed Reza Attarzadeh Hosseini, Morteza Motahari Rad , Navideh Moien Neia ,
Volume 19, Issue 7 (10-2016)
Abstract
Background: The aim of this study was to investigate the effect of resistance training with different intensities on serum myostatin and follistatin levels in sedentary young women.
Materials and Methods: In this practical and semi experimental study, 24 sedentary young women with range of 20-30 years and BMI 22-25 kg/m2 were selected by convenience sampling. Then, the volunteers were randomly assigned into two groups, [resistance training group with low intensity (40-60% of one repetition maximum) and high intensity (70-90% of one repetition maximum)]. The training protocols included: 8 weeks, 3 times a week. Blood samples (5cc) were obtained at baseline and 48 hours after at the end of the study; Also Serum levels of myostatin and follistatin were measured by ELISA methods. Data were analyzed using analysis of variance of repeated measures test by SPSS at the significant level (p<0.05).
Results: There was a significant increase in the levels of follistatin and follistatin to myostatin ratio in high intensity group (p≤0.05). Also there was a significant decrease in the levels of myostatin in high intensity group (p≤0.05); however, there was no significant change in the levels of follistatin, myostatin and follistatin to myostatin ratio in low intensity group (p≥0.05). Also there was no significant change in these variables in high intensity group compared to low intensity group (p≥0.05).
Conclusion: It’s seems that the activation of important myogenic and myostatic factors in sedentary young women need to do high intensity resistance training.
Hosna Rastegarpouyani, Seyed Masoud Hosseini, Seyed Reza Mohebbi, Pedram Azimzadeh, Shabnam Kazemian, Mahsa Saeedi Niasar, Afsaneh Sharifian, Mohammad Reza Zali,
Volume 20, Issue 2 (5-2017)
Abstract
Background: Parvovirus 4 (PARV4) was first discovered in 2005, in a hepatitis B virus–infected injecting drug user (IDU). To date, the best evidence about PARV4 transmission is parenteral roots and comes from IDU individuals. It seems that the prevalence of the virus in the normal population is very low. In this study, we investigated the prevalence of PARV4 virus among patients with chronic HCV infection compared with healthy controls and related risk factors among these groups.
Materials and Methods: A total of 206 patients, including 103 patients with chronic HCV infection and 103 healthy controls, were studied by use of nested-PCR and also real-time PCR techniques.
Results: AST enzyme levels with a mean of 40.45+34.84 and 18.58+5.9 in patients and healthy group respectively and the amount of enzyme ALT among patients with a mean of 40.45+35.75 and 21.50+11.35 in patients and healthy group respectively, were reported. Finally, after screening all DNA samples from patients and controls, we discovered that none of these people are infected with the PARV4 virus.
Conclusion: This study is the first to investigate the occurrence of PARV4 among HCV patients in Iran. The results show that, the virus is not important in Iranian population, even in patients with blood born infections such as HCV and further studies in other areas and various groups are required.
Morteza Motahari Rad, Seyyed Reza Attarzadeh Hosseini,
Volume 20, Issue 2 (5-2017)
Abstract
Background: The aim of this study was to investigate the response of the most important angiogenic and angiostatic factors to a session activity before and after a period of L-Arginine supplementation in active men.
Materials and Methods: In this practical and semi experimental study, 22 active men were selected by convenience sampling method and they were randomly assigned into supplement (n=11) and placebo (n=11) groups. Baseline levels of VEGF and endostatin were measured, then subjects participated an exhaustive treadmill protocol in pre-test and post-test. Immediately and two hours after the protocol, 3 cc blood samples were prepared. The subjects used daily 0.1 g.kg-1 respectively taking l-arginine and placebo for 14 days. The results were analyzed at the significant level (p<0.05).
Results: Immediately after exercise, the levels of VEGF and VEGF to endostatin ratio were significantly decreased in both groups compared to baseline (p≤0.05), and two hours later this change were lower than the baseline value (p≤0.05). The levels of endostatin immediately after exercise were significantly increased in both groups compared to baseline (p≤0.05) and two hours later this change were lower than the baseline value (p≤0.05). Before and after L-Arginine supplementation, the levels, of VEGF and VEGF to endostatin ratio immediately after exercise were not significant(p≥0.05). while this change in the supplementation group were significantly increased two hours after exercise (p≤0.05). There was no significant change in the levels of endostatin between two groups immediately after exercise (p≥0.05); however, these changes were significantly decreased two hours after exercise (p≤0.05).
Conclusion: It seems that short-term L-arginine supplementation probably stimulate angiogenesis factors in response to exercise in active men.
Azam Alinaghipour, Marziyeh Tavassoli, Elahe Seyed Hosseini, Abolfazl Ardjmand,
Volume 20, Issue 7 (10-2017)
Abstract
Abstract
Background: Neuronal damage following seizures and epilepsy is one of the main causes of disabilities and mortality worldwide. In recent years, preconditioning has been introduced as a novel strategy for the prevention of brain damage. Preconditioning is a phenomenon in which a minor noxious stimulus protects from a subsequent more severe insult. The aim of present study was to examine the effect of ethanol (Eth) preconditioning on pentylenetetrazole (PTZ)-induced impairment memory in the inhibitory avoidance model.
Material and Methods: This study was carried out on 45 adult male Wistar rats (180-200 g). Animals were assigned into five groups: Control, Eth 0.25, Eth 0.5, PTZ and Eth (0.5) +PTZ (n=9, for all groups). Eth-preconditioning was induced 6 days before the injection of PTZ. The animals were tested in a single trial step-through inhibitory test in two sessions (train and test). Then locomotor activity of rats was recorded in the open-field apparatus and NR1 mRNA expression in the hippocampus was measured by real-time PCR technique.
Results: One-way ANOVA revealed that the Ethanol preconditioning did not impair inhibitory memory. Further, post-test analyses showed that Ethanol preconditioning significantly prevented from PTZ-induced memory impairment, and increased NR1 subunit mRNA expression in PTZ-induced memory impairment group. In addition, one-way ANOVA for the locomotor activity showed no significant difference between the groups.
Conclusion: Our results showed that a pre-conditioning treatment with Ethanol
(0.5g/kg/day), 6 days before PTZ-induced memory impairment may provide a kind of neuroprotection in rats.
Abolfazl Ahani, Mohammadmehdi Hassanzadeh-Taheri, Mehran Hosseini, Mohammad Hassanpour-Fard,
Volume 20, Issue 8 (11-2017)
Abstract
Abstract
Background: The rhizome of Iris songarica Scherenk has been prescribed as anodyne in Persian traditional medicine system. However, its effects have never been investigated experimentally. Thus, the present study was designed to evaluate the antinociceptive and anti-inflammatory effects of alcoholic extract of Iris songarica Scherenk rhizome in mice.
Material and Methods: In this experimental study, adult male balb/c mice were used. 40 animals were allocated into five equal groups (control, morphine 5mg/kg, the extracts at doses of 100, 200 and 300 mg.kg) and tested for antinociceptive evaluation via using hot-plate in 30,60 and 120 minutes after the investigations. Also, the other 36 mice were divided into six equal groups (no-inflammation control, inflammation model, dexamethasone 4 mg/kg and the extracts at doses of 100, 200 and 300 mg.kg) and evaluated for anti-inflammatory activity in xylene induced inflammation model. All the investigations were done via intraperitoneal injection. Data were analyzed using one-way ANOVA or Kruskal-Wallis tests in SPSS.
Results: Compared to the control group, the extract at the all doses could increase latency time in hot plate test at 30, 60 and 120 minutes after investigation (p<0.05).This potential was comparable to morphine in the high doses or long time. In addition, the extracts at the all doses exhibited high anti-inflammatory activity which was comparable to dexamethasone (p<0.001).
Conclusion: The results of present study clearly showed that Iris songarica Scherenk rhizome has antinociceptive and anti-inflammatory activities in mice.
Iman Jamhiri, Saber Zahri, Davood Mehrabani, Zahra Khodabandeh, Ramin Yaghobi, Seyed Younes Hosseini,
Volume 20, Issue 11 (2-2018)
Abstract
Abstract
Background: High morbidity and limited therapies of hepatic fibro genesis are important factor for better understanding the molecular mechanisms of the disease. Advances in the understanding of the molecular behavior of hepatic stellate cells (HSC) allow the progress of a field dedicated to anti-fibrotic therapy. Melanoma differentiation associated gene-7 (IL-24/mda-7) as a gene induced during terminal differentiation in human melanoma cells, but the inflammatory response of cells to IL-24/mda-7 is not entirely cleared.
Materias and Methods: LX-2 cells (a human hepatic stellate cell) were treated by leptin (positive control), media (control negative), or were transfected by empty plasmid and pcDNA3.1/mda-7. The inflammatory state was evaluated through measuring the mRNA expression level of inflammatory molecule, IL-1β. The role of IL-24/mda-7 modulation on inflammatory response was assayed using SOCS1 and SOCS3 gene expressions.
Results: The expression levels of IL-1β, SOCS1 and SOCS3 were compared in LX-2 cell line groups. The expression of the IL-1β in the transfected cells was higher than the control cell, but it was not significant. The results indicated that the expressions of SOCS1 and SOCS3 were up-regulated following pcDNA 3.1/mda-7 transfection into LX-2 cells compared to control plasmids (p=0.0179, p=0.0428).
Conclusion: The endogenous IL-24/mda-7 exhibited a significant modulatory effect on stellate cells. Therefore, IL-24/mda-7 and relevant signaling pathways could be employed as a target for fibrosis treatment.
Ali Reza Morad Abadi, Mohammad Arjomandzadegan, Navid Emami, Manijeh Kahbazi, Azam Ahmadi, Saeed Falahat, Seyyed Hossein Hosseini, Mehdi Kargaran, Parisa Khosravi,
Volume 21, Issue 4 (8-2018)
Abstract
Background and Aim: Ziehl Nelson staining, fluorescent and also culture are the standard methods for the diagnosis of tuberculosis. In this study, the performance of conventional cultivation methods was compared with Flash PCR.
Materials and Methods: A total of 56 sputum samples from patients with suspected tuberculosis in Tuberculosis Center of Arak city were collected and Ziehl–Neelsen and culture in Löwenstein–Jensen medium were accomplished. Moreover, DNA from all of the 56 sputum samples was extracted by Chelex100 method. Molecular evaluation was accomplished by Flash PCR kit containing probes and primers for gene amplification IS6110. Positive and negative controls together with samples were used in a MTC410 apparatus for amplification. FD-12 apparatus was used to evaluate the results. In addition, electrophoresis on agarose was used for confirmation of the results.
Findings: From 56 sputum samples of suspected TB patients, 20 samples were positive and 36 samples were negative on microscopic evaluation and culture methods. FLASH-PCR molecular analysis showed that all of 20 positive samples were positive in molecular methods, too. On the other hand, three of sputum samples that were negative by culture and staining were positive in FLASH-PCR method. One of these 3 patients, received Isoniazid, pyrazinamide and ethambutol antibiotic by responsible medicine. All results were confirmed using conventional electrophoresis.
Conclusion: In some negative samples, possibly because of the small number of bacteria in sample or a defect in the sampling, the Flash PCR may due good advantages. Therefore, due to the low cost, this method is recommended for routine use.
Mohammad Khalili Kelaki, Ruholah Karimzadeh , Neda Soleimani, Seyed Masoud Hosseini, Maghsud Arshadi,
Volume 22, Issue 3 (8-2019)
Abstract
Background and Aim: Background and Aim: Photodynamic therapy is a minimally invasive approach to cancer, which is used to combine non-toxic photosensitizer and visible light to produce reactive oxygen species and destroy tumors. This study aimed to investigate the cytotoxicity effect of Graphene Oxide (GO)as an organic matter with many oxygen groups on photodynamic on destroying cancer cells.
Materials and Methods: This study was performed on breast cancer cells (MCF-7) in vitro. The study groups included the first group of drug with different concentrations of graphene oxide (333.3, 285.7, 230.7, 166.6, 90.9,
47.6 µg/ml), the second group co-drug and laser light irradiation and the control group consisted of cells treated only with laser irradiation and the control group was treated with no treatment. Cells were exposed to visible laser irradiation (405 nm) at 0.1 W / cm2. Cell viability was determined by MTT assay.
Ethical Considerations: This study with research ethics code SBU/S.1397.46A has been approved by research ethics committee at Shahid Behesht University of Tehran, Iran.
Findings: The results of in vitro experiments showed that the dark toxicity of graphene oxide at concentrations of less than the 90.9 μg / ml concentration had no significant effect on cancer cells. Also, laser light alone don’t has toxic effect on cells. But graphene oxide-mediated dynamic light therapy has reduced the bioavailability of cancer cells on average by 21% over dark toxicity. Results are presented as mean of three independent replications, standard error, and p< 0.05 was considered significant.
Conclusion: In this study, graphene oxide is fully biodegradable at concentrations below a certain value, but with increasing concentration, the toxicity effect increases. With exposure to light and graphene oxide, viability decreses that it is more effective for in vivio studies.
Seyed Vali Kazemi Rezaei, Keivan Kakabraee, Saeedeh Sadat Hosseini,
Volume 22, Issue 4 (9-2019)
Abstract
Background and Aim Psychological factors play a significant role in the exacerbation of cardiovascular diseases. This study aimed to investigate the effectiveness of teaching emotion regulation skill (based on dialectical behavioral therapy) on cognitive emotion regulation and Quality of Life (QoL) of patients with cardiovascular diseases.
Methods and Materials The present study has a quasi-experimental design with pretest-posttest and the control group. The statistical population of the study included all patients with cardiovascular diseases in Kermanshah City, Iran in 2018. Among them, 30 participants were selected by simple random sampling method. Then, they were randomly assigned to the two groups of experimental and control (each group 15 patients). We performed the intervention of excited ordering education based on dialectical behavioral therapy for the experimental group in eight 90-minute sessions, while the control group did not receive any intervention during this period. To collect study information, we used a short form of the emotional cognitive regulation questionnaire and MacNew Quality of Life Questionnaire. To analyze the data, we used the multivariate analysis of covariance in SPSS V. 20.
Ethical Considerations The Research Ethics Committee of Kermanshah University of Medical Sciences approved this study (Code: IR.KUMS.REC.1397.39).
Results The results showed that the scores of Positive Cognitive-Emotional Strategies and quality of life of cardiovascular patients after training of emotional regulation skills based on dialectical behavioral therapy in experimental group significantly increased in comparison with control group, and also Negative Strategies Scores were decreased (P<0.01).
Conclusion Based on our positive study results, we recommend the therapists to use psychological treatments as complementary therapies for these patients.
Mohammad Saeed Poorsoleiman, Seyed Seyed Ahmad Hosseini, Alireza Etminan, Hamid Abtahi, Ali Koolivand,
Volume 22, Issue 5 (11-2019)
Abstract
Background and Aim The widespread application of crude oil and its products has caused numerous environmental pollutions. This study aimed to isolate, identify, and determine a bacterial strain’s potential of oil degradation isolated form oily sludge.
Methods & Materials After preparing the oily sludge in the sterile containers and cultivating in Bushnell-Haas medium, 24 distinct bacterial colonies were obtained. After performing biochemical and molecular tests, the “Acinetobacter radioresistens strain KA2” with the highest growth rate and crude oil degradation was selected. Then, degradation of various concentrations of crude oil at different PHs (5, 6, 7, 8 and 9), bacterial adherence to hydrocarbons and emulsification index of the selected strain were measured. Total petroleum hydrocarbons were determined by gas chromatography.
Ethical Considerations This study has been approved by the Research Ethics Committee of Islamic Azad University of Kermanshah Branch (code: 19250587962001 ).
Results The results indicated that the removal efficiency of crude oil at concentrations of 1, 2, 3, 4, and 5% were 65.24, 76.14, 53.81, 31.84, and 25.21%, respectively. Crude oil removal at pH values of 5, 6, 7, 8, and 9 was 42.4, 69.16, 65.24, 59.41 and 48.24%, respectively. Bacterial adherence to hydrocarbons and emulsification index of the isolated strain were calculated to be 13.69 and 59.14%.
Conclusion The isolated bacterium is an efficient strain in treating the crude oil and petroleum compounds.
Zeinab Abdolhosseini, Isaac Rahimian Boogar, Siyavash Telepasand,
Volume 22, Issue 6 (February & March 2020)
Abstract
Background and Aim: Physical complaints that have no clear cause are a process that is commonly seen in patients with Somatic Symptom Disorder (SSD). The increasing number of patients with this disorder and its related chronic symptoms including changes in quality of life and loss of individual efficiency has created social and psychological economic costs for these patients and their families.
Methods & Materials: This descriptive cross-sectional study conducted on 70 patients with SSD having digestive symptoms and chronic pain referred to the health centers in Semnan, Iran in winter 2018. They were selected using a convenience sampling method. The data collection tools were 15-item Patient Health Questionnaire Physical Symptoms (PHQ-15) and Rorschach test (Exner’s Comprehensive System). In order to analyze the collected data, multiple linear regression analysis, logistic regression analysis, and multivariate ANOVA were performed in SPSS v. 22 software.
Ethical Considerations: The present study was approved by the Research Ethics Committee of Semnan University of Medical Sciences (code: IR.SEMUMS.REC.1397.029).
Results: Perceived location indices including D and Dd scores in Rorschach test were able to significantly differentiate the SSD patients from controls (P<0.05). In the logistic regression model, 70% of participants were classified properly.
Conclusion: There is difference in projective responses between SSD patients and controls, and patients were less holistic. Anxiety and psychiatric symptoms were also higher in patients with SSD.
Fatemeh Sadat Hosseini Poor Abardeh, Mandana Niknam,
Volume 24, Issue 3 (August & September 2021)
Abstract
Background and Aim: Anxiety is one of the common disorders affecting the treatment process in patients with breast cancer. Regarding the importance of spiritual health on anxiety in cancer patients, the purpose of this study was to investigate the relationship between spiritual health with existential anxiety and morbid anxiety in the female with breast cancer.
Methods & Materials: The research method was descriptive-correlational. The statistical population included all female patients with breast cancer referred to Imam Reza Oncology and Radiotherapy Center in Mashhad in 2017. A total of 195 patients with breast cancer were selected through random sampling. Data collection tools included Beck Anxiety Inventory (1990), Lawrence & Good Existential Anxiety Inventory (1974), and Paulotzin & Ellison Spiritual Health Inventory (1982). Data were analyzed using Pearson correlation and multivariate regression.
Ethical Considerations: This study was registered by the Ethics Committee of Islamic Azad University E-Campu (Code: 950261902191).
Results: The results showed a significant positive relationship between spiritual and existential dimensions of spiritual health with existential anxiety (P>0.01). But the relationship between two dimensions of spiritual health and patients’ anxiety was not significant (P>0.01).
Conclusion: Considering the importance of spiritual health in existential anxiety and morbid anxiety, strengthening spiritual health can influence cancer patients’ anxiety.
Masoud Golpayegani, Zahra Fayazi, Yasin Hosseini,
Volume 24, Issue 5 (December & January 2021)
Abstract
Background and Aim: Patellofemoral Pain Syndrome is one of the most common musculoskeletal problems in the elderly that Can affect their daily activity. This study aims to compare the effectiveness of a period strengthening core stabilization exercise with the Knee strengthening exercises on improving pain in female athletes with Patellofemoral Pain Syndrome.
Methods & Materials: In this study, 20 female athletes with Patellofemoral Pain Syndrome participated. They were accidentally divided into two groups: strengthening core stabilization exercise (10 people( and strengthening knee exercise (10 people). A visual analog scale measured patients’ pain before and after eight weeks of practice interventions. Paired t-test and independent t-test were used at the significant level of (P<0.05) to analyze the results.
Ethical Considerations: This study was approved by the Research Ethics Committee of Bu Ali Sina University Hamedan (Code: IR.BASU.REC.1398.032).
Results: The results showed that the pain level in both groups decreased significantly after strengthening core stabilization exercises (P=0.006) and the Knee strengthening exercises (P=0.000). Although intergroup comparison did not show a significant difference in the results (P̀=0.064), the calculation of the effect showed a more significant effect of strengthening knee exercise [ES=1.8) on the improvement of pain compared to the strengthening core stabilization group (ES=0.7).
Conclusion: The results showed that knee strengthening and core stabilization exercises reduced the pain. But due to the higher effectiveness of knee strengthening exercises in improving pain, it is recommended to use this protocol to reduce the pain of these patients.
Pardis Mirmoeini, Mohammad Hosseini Bayazi, Javad Khlatbari,
Volume 25, Issue 1 (April & May- 2022)
Abstract
Background and Aim Given the increasing number of patients with multiple sclerosis and the psychological complications that affect this group, the present study was conducted to compare the effectiveness of acceptance and commitment therapy and compassion-focused therapy for these patients
Methods & Materials This research was a quasi-experimental study with a pre-test-post-test design with a control group. A total of 45 patients with multiple sclerosis were selected from MS patients in Tehran Clinic, Tehran City, Iran, in 2020. They were randomly divided into three groups: the first group was under treatment based on acceptance and commitment therapy, the second group was assigned to the compassion-focused therapy, and the third group was the control. The participants completed the Connor and Davidson resilience questionnaire and the Pennsylvania concern questionnaire in the pretest and post-test stages. The first and second groups participated in eight sessions of acceptance and commitment therapy and ten sessions of compassion-focused therapy, respectively. The control group did not receive any intervention. The post-test was done at the end of the therapy sessions. Data were reported by analysis of covariance.
Ethical Considerations This research was approved by the Torbat Jam Branch, Islamic Azad University (Cod: IR.IAU.TJ.REC.1399.012).
Results The results of univariate analysis of covariance were obtained at the statistical level of P<0.05. In this regard, F=5.88 for resilience and F=42.60 for anxiety intensity were obtained, which indicated the greater effectiveness of acceptance and commitment treatment.
Conclusion Considering the effectiveness of both treatments, it is suggested that these treatments be given more attention to controlling patients’ psychological symptoms.
Mr Mohammad-Mehdi Khashmin, Mrs Farahnaz Hosseini, Mrs Samira Jafari, Mrs Sepideh Najafzade, Mr Human Ghasemi, Mrs Niloufar Darvishi, Mrs Asal Golchin,
Volume 25, Issue 4 (October & November 2022)
Abstract
Introduction: Depression is an injury to the central nervous system that is caused by several factors that affect a large number of people around the world. Emotion regulation refers to the processes by which we influence what emotions we experience, when we experience them, and how we express them. The aim of this study was to investigate the role of emotion regulation in predicting depressive symptoms in students of Kermanshah University of Medical Sciences.
Methods: The present study is a descriptive correlational study. Participants were all students of the School of Nursing and Midwifery of Kermanshah University of Medical Sciences during 2020-2021. Three hundred and five participants were selected by available sampling method and randomly. Informed consent forms got from the participants, then they completed the Beck Depression Inventory - Second Edition (BDI-II) and the Cognitive Emotion Regulation Scale (CERQ-18). This research was reviewed in the ethics committee of Kermanshah University of Medical Sciences and approved with the ID IR.KUMS.REC.1400.623.
Results: In this study, the study population was 305 people, 9 of whom were excluded from statistical analysis due to incomplete answers. Total mean age was 50.08 ± 191.30 Of these, 198 (66.9%) were female and 98 (33.1%) were male. Self-blame strategies (β = 0.31, P≤0.001), positive reassessment (β = -0.26, P≤0.001), catastrophic (β = 0.26, P≤0.001), numerical importance (β = -0.12, P≤ 0.001) and positive refocus (β = -0.10, P≤0.001) in five steps predict 40% of the variance of depression. Inconsistent strategies such as self-blame and catastrophe directly and positive reassessment, insignificance and positive refocus inversely predict depression. Mahalanobis distance was used to investigate multivariate throw values. Statistical assumptions were tested by performing an initial regression analysis and evaluating the scatter plot of residues. After confirming the regression assumptions, the data were analyzed using Pearson correlation and stepwise regression. The findings of our study showed that there is a significant direct relationship between self-blame and catastrophic thinking as maladaptive strategies of cognitive emotion regulation with depression. Also in our study among adaptive emotion regulation strategies; Positive refocusing, positive reassessment, and a small number had a significant negative correlation with depression.
Conclusions: The results of our study showed that emotion regulation strategies play an important role in predicting the occurrence of depression. Therefore, it is necessary for health policy makers to strengthen adaptive emotion regulation strategies in designing and modifying interventions related to depression.
