Showing 26 results for Farahani
Saeed Hajihashemi, Razie Rajabi, Atefeh Ghiasabadi Farahani,
Volume 22, Issue 5 (11-2019)
Abstract
Background and Aim Gentamicin antibiotic has some side effects such as nephrotoxicity. The aim of this study was to evaluate the post-treatment effects of using hydroethanolic extract of Origanum Vulgare (OV) on nephrotoxicity caused by gentamicin.
Methods & Materials In this study, 32 male Wistar rats were divided into four groups of control (n=8), gentamicin (n=8; 100 mg/kg/day intraperitoneally for 8 days and gavage of distilled water for 2 days), OV extract group (intraperitoneal injection of normal saline for 8 days and using 40 mg/kg OV extract by gavage for 2 days), and gentamicin+ OV extract (intraperitoneal injection of gentamicin 100 mg/kg/day for 8 days and using 40 mg/kg OV extract by gavage for 2 days). The concentration of urea, creatinine, sodium, potassium and osmolarity were measured in plasma and urine samples. The right kidney was used to measure Malondialdehyde (MDA) and Ferric Reducing Antioxidant Power (FRAP).
Ethical Considerations This article was obtained from a research proposal approved by the Research Ethics Committee of Arak University of Medical Sciences (Code:IR.ARAKMU.REC. 1394.284)
Results Post-treatment administration of hydroethanolic extract of OV significantly decreased the concentration of urea, creatinine, absolute sodium excretion, relative sodium and potassium excretion, and MDA levels but significantly increased creatinine, urine osmolality and FRAP levels.
Conclusion Oral administration of OV extract as post-treatment method improved nephrotoxicity caused by gentamicin use by reducing oxidative stress of oxygen free radicals and lipid peroxidation in the affected kidneys.
Fatemeh Shahrestan, Parvaneh Jafari, Aram Gharebaghi, Iman Khani Farahani, Esmaeil Shahrestan,
Volume 23, Issue 2 (June & July 2020)
Abstract
Background and Aim: Diabetes mellitus is one of the leading causes of death, and its prevalence is increasing annually because of the change in lifestyle. Increased blood glucose level and dyslipidemia are the major symptoms of this metabolic disease. Currently, the main and effective treatment for diabetes is the use of medication such as insulin. Its control by using herbal products has received a lot of attention in the world. The aim of this study is to evaluate the effects of bioflora (a probiotic supplement) and aqueous extract of cinnamon in improvement of blood glucose level, dyslipidemia, and reduction of cardiovascular diseases in diabetic rats.
Methods & Materials: Thirty-five male Wistar rats were prepared and randomly divided into five groups of negative control, positive control, probiotic (treated with bioflora 3.2×108 CFUs/day for 30 days), cinnamon (treated with 200 mg/kg of cinnamon aqueous extract for 30 days), and probiotic + cinnamon. Diabetes was induced by intra-peritoneally injection of streptozotocin. The rats’ weight, blood glucose level, lipid profile, high sensitivity C-Reactive Protein (hs-CRP) and Atherogenic Index (AI) were measured at the end of experiment to predict the risk of cardiovascular diseases.
Ethical Considerations: This study ethically approved in Research Centre of Islamic Azad University of Arak (Code: IR.IAU.ARAKREC1397.005). All interventions performed in accordance with the Guide for Care and Use of Laboratory Animals prepared by the Institute of Laboratory Animal Resources.
Results: Induction of diabetes caused severe weight lost in rats, but the weight loss was lower in groups treated with probiotic. The blood glucose level in probiotic + cinnamon group was significantly reduced. Bioflora reduced triglyceride, cholesterol, and Low-Density Lipoprotein Cholesterol (LDL-C) levels, while cinnamon extract significantly reduced triglyceride and LDL-C levels compared to the positive control group. AI and hs-CRP values were reduced in the probiotic group compared to control groups. There was no synergistic effect by combined use of bioflora and cinnamon extract.
Conclusion: Bioflora effectively prevented dyslipidemia by improving intestinal microbiota, lowering blood glucose level, and improving lipid profile and, therefore, reduced the risk of cardiovascular diseases.
Yazdan Ghandi, Nooshin Sajadei, Seyed Mojtaba Hashemi, Javad Farahani,
Volume 24, Issue 2 (June & July 2021)
Abstract
Background and Aim: Considering the importance of childhood obesity and easier correction of related factors in this age group, the present study aimed to investigate the role of some factors related to family, nutrition, and lifestyle on childhood obesity.
Methods & Materials: This age-matched case-control study was performed on 150 obese and 150 healthy children, aged 2-15 years referring to Amir-Kabir Hospital in Arak City, Iran. Obesity was calculated based on Body Mass Index (BMI). Required information, including family factors, nutritional factors, and lifestyle characteristics were collected by a checklist.
Ethical Considerations: This study was approved by the Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1396.119).
Results The results of Odds Ratio (OR) with 95% of Confidence Interval (CI) were in favor of father’s age of 25-35 and over 35 years (0.24), respectively, father’s overweight and obesity (3.87 and 3.57), mother’s overweight and obesity (3.81 and 5.5)7, more than three children per household (3.33), low and high consumption of fruits and vegetables (0.3 and 0.19), breakfast eating (0.43), dietary supplementation (2.68), consuming fast food (3.98), more than two hours of playing a computer game (3.5), chewing well (0.38), using food as a reward (1.89), as well as participating in food and table preparation (3.14). We found a dose-response association between children’s obesity and parents’ BMI, the number of children, and computer games.
Conclusion: Obesity is associated with some factors related to the family, such as nutrition, computer games, and lifestyle characteristics. Due to various risk factors and adjustable safeguards, it is necessary to provide families and children with proper education to reduce obesity.
Ms Kobraa Mastery Farahani, Dr Soghra Akbari Chermahini,
Volume 25, Issue 5 (December & January 2022)
Abstract
Introduction: Investigating the psychological issues of patients with diabetes, especially in adolescence and youth, is particularly important. Therefore, this study aims to compare the health anxiety and response inhibition of people with type 1 diabetes with healthy people.
Methods: This research is a description of the causal and comparative types. Its statistical population consists of all boys and girls aged 14 to 24 years old with type 1 diabetes in Arak city who were referred to the treatment clinics of this city in 1400. From this population, 30 people were selected by purposive sampling, and 34 healthy teenagers participated in this study as a comparison group. The tools of this research included the health anxiety questionnaire (Salkoskis and Warwick, 2002) and the open-ended task, and multivariate analysis of variance was used to analyze the data.
Ethical Considerations: The present research has been registered with the code IR.ARAKU.REC.1401.015 in the Ethics Committee of Arak University.
Results: The present study's findings showed a significant difference between health anxiety and cognitive inhibition of adolescents with type 1 diabetes and healthy adolescents (P<0.05).
Conclusions: The results of this research show the higher level of health anxiety and poor performance of adolescents with type 1 diabetes in choosing the right answer and neglect the wrong answer, which indicates a weakness in their inhibition system. Considering the placement of these problems along with the psychological characteristics of adolescence, it is suggested to use suitable psychological treatment approaches and suitable cognitive rehabilitation interventions to solve or reduce these problems and increase the health of these patients.
Miss Homa Rastegari, Dr Davood Hekmatpou, Dr Ramiz Kamrani, Dr Moloud Farmahini Farahani,
Volume 26, Issue 1 (April & May 2023)
Abstract
Introduction: One of the common problems of patients with covid-19 is the occurrence of respiratory problems that may accompany the person for a long time. Also, based on clinical and research evidence, different degrees of anxiety and stress have been observed in those who have recovered from this disease. This study was conducted with the aim of determining the effect of diaphragmatic breathing on dyspnea and state anxiety in patients with covid-19.
Methods: This study was a randomized clinical trial conducted in 2021-2022. The study population consisted of 78 patients with covid-19 hospitalized in Amir al-Momenin Hospital in Arak city, who were selected by available sampling and divided into two groups of 40. In this study, the Spielberger anxiety inventory, Borg scale, MRC breathlessness scale and measurement of blood oxygen saturation were used. The test group received diaphragmatic breathing training on the day of discharge and performed the exercise for ten minutes, and after discharge, they performed diaphragmatic breathing twice a day (ten minutes each time) at home for a week. Questionnaires were completed by the patients before the intervention, immediately after and one week later. The data was analyzed with SPSS software version 23 at the level (P < 0.05).
Results: The findings showed that the mean anxiety score of the patients immediately and one week after the intervention in the test group was significantly lower than the control group (P < 0.001). The mean oxygen saturation in the test group after the intervention was significantly higher than the control group (P < 0.001). Also, a significant difference was observed between the mean dyspnea scores using the MRC and Borg dyspnea scales after the intervention in the two groups (P < 0.001).
Conclusions: The results showed diaphragmatic breathing reduced anxiety and shortness of breath in patients with covid-19 after discharge. Therefore, teaching this simple and effective method is recommended for these patients during discharge from the hospital.
Umm Kulsum Tabarte Farahani, Naimeh Akbari Torkestani, Leila Khazaei, Dr Mehdi Ranjbaran, Masoomeh Davoodabadi Farahani,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Sexual self-efficacy is a fundamental concept in behavior, health, and sexual performance that changes over time due to events such as pregnancy and childbirth. The present study was conducted to investigate factors affecting sexual self-efficacy in pregnant women in Arak City.
Methods: The current research is a cross-sectional, descriptive, and analytical study conducted with 234 pregnant women aged 18 to 40 who had minimal reading and writing literacy and lived with their husbands. Ten comprehensive urban health centers were selected using cluster sampling. Data were collected through a demographic information checklist and a sexual self-efficacy questionnaire. Data analysis was done using Mann-Whitney U and Kruskal-Wallis and (LSD) tests.
Results: The mean score of sexual self-efficacy of pregnant women was 28.51 ± 6.45 and was at a high level. Kruskal-Wallis test showed that the sexual self-efficacy of pregnant women is unrelated to their education (P = 0.2). There is a significant relationship between education and the education of their spouses (P = 0.04). (LSD) test showed a significant difference between different levels of education of husbands and the sexual self-efficacy of pregnant women. Also, no significant relationship was observed between the mean score of sexual self-efficacy and other variables.
Conclusions: The sexual self-efficacy of pregnant women is related to the education of their husbands, so it is suggested to provide a suitable platform for increasing the knowledge and awareness of men.
