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Background and Aim: Exercise aerobic is associated with increased creatine kinase and blood lactate immediately after exercise, leading to increased muscle damage and undesirable changes in many cellular markers including serum creatine kinase. In such situations, consuming nutrients and supplements such as coenzyme Q10 may prevent metabolic stress damage by increasing buffering power. However, comprehensive studies have not been performed on the effects of this nutrient on the index of muscle injury and fatigue caused by exercise.
Methods & Materials: For this purpose, 20 inactive volunteer men were randomly divided into two groups of 10-person Coenzyme Q10 supplement (2.5 mg/kg body weight) and quasi-drug (2.5 mg/kg body weight Dextrose). All subjects participated in the Bruce test exercise contract after 14 days of supplementation. Blood sampling was performed in four stages including baseline, after supplementation, immediately after exercise and two hours after exercise. Creatine kinase, lactate and cortisol indices of both groups were measured during these four stages. Data were analyzed by means of standard deviation and repeated measures ANOVA, Bonferroni post hoc and Independent T-test using SPSS V. 17 at the significant level of 0.05.
Ethical Considerations: This article has been approved by the ethics committee of Tabriz School of Medical Sciences with the ethics code IRCT 201203104663N8.
Results: The results showed that 14 days of Coenzyme Q10 supplementation had a significant effect on cortisol level (P<0.05). In addition, one session of exhausting aerobic activity increased creatinine kinase and lactate (P<0.05). On the other hand, creatinine kinase did not differ significantly after exercise (P>0.05). 
Conclusion: According to the results of the present study, 14-day supplementation of Coenzyme Q10 may reduce the cellular damage induced by exhaustive aerobic activity in inactive men and prevent an increase in blood lactate levels.

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Background and Aim: Fungal infections are among the most critical and common issues for hospitalized patients, especially in intensive care units. This study aimed to determine the fungal contamination of indoor air and surfaces in sensitive wards of the Arak University of Medical Sciences educational hospitals and determine the drug susceptibility pattern of isolated species.
Methods & Materials: In this descriptive cross-sectional study, 63 air samples were taken from sensitive hospital wards using the one-stage Anderson method, and 63 surfaces samples were taken using wet cotton swabs and cultured in saprodextrose agar medium containing chloramphenicol. Identification of the genus and, as far as possible, the species of fungi was performed using the culture method on the slide. Drug susceptibility testing was performed on isolated species by broth microdilution method (CLSI-M38A2 standard). 
Ethical Considerations: This study was approved by the Research Ethics Committee at Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1395.315).
Results: From the total samples, 18 species of fungi were isolated. These included: Aspergillus niger (8), Aspergillus flavus (4), Aspergillus fumigatus (2), Rhizopus spp. (2), Mucor spp. (1) and Fusarium spp. (1). In the drug sensitivity assay, instances of resistance included: Partial sensitivity of Aspergillus fumigatus to Itraconazole (1), Partial sensitivity of Aspergillus niger to Ketoconazole (1), and Resistance of Aspergillus niger to Itraconazole (1).
Conclusion: The pattern of nosocomial fungal infection with pathogenic fungi and the drug susceptibility pattern of these organisms in other regions of Iran and the world is relatively consistent with the present study results. And drugs listed in global guidelines for treating these infections, such as voriconazole and caspofungin in the treatment of invasive aspergillosis and amphotericin B in the treatment of invasive mucormycosis and Fusarium wilt, are now effective drugs.

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Introduction: Beyond the members of the charter board, the horizon of Amedwar Kanandah for the sake of Bimaran Niyazmand, the member of the board of the board. In parallel, there is a new medical science in New Mutrah, in the opinion of specialists who claim that it is a model and that they have a source for beyond the organs with children. Definitively The current issue is that of new topics and the question of programs in the possession of jurisprudence and rights, which must be carefully selected from the angles that are the subject of jurisprudence debate.
Methods: This is a book in the form of a textbook and a description - an analysis with the use of the books of science and jurisprudence of his room.
Results: This type of child is based on the basis of investigations, which are believed to be valid, according to the permissibility of the organs that are nozadan with severe cranial defects, i.e., in the womb of a mother, or from a cutaneous period, but from birth in the middle of my heart; A defensible issue.
Conclusions: The use of the nostril organs affected by the cornea with limitations of the cervical spine, but with a significant meaning in the development of Rastafarian, and the use of non-main organs based on multiple rational and legal evidences; Milabashed project. The parts of my life are afflicted with severe corneal ulcers, based on the inevitability and inevitability of the disease, and the reason for the fact that the situation is similar to the meaning of the disease. Develop a legitimate development in the most vigorous manner, and the issue of the necessity of preserving human dignity This is an issue that cannot be denied. But from the point of view of the role that is not a conditional legality, it is a present issue with conditional auspices in no severe form.
 

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Abstract
Introduction: Insomnia and sleep disorders are related to a decrease in physical and mental health and quality of life. The purpose of this study was to investigate the effect of sleep deprivation on blood sugar, cortisol and insulin levels in athletes compared to non-athletes.
Methods: In this semi-experimental study, 14 healthy men participated in two groups of athletes (7 people) and non-athletes (7 people). One night of sleeplessness (8 hours) was applied to the subjects of both groups. According to the objectives of the research, blood samples were taken from all the subjects in two stages. The data were analyzed using the dependent t test for intra-group comparison and independent t test for inter-group comparison at a significance level of 5%. In conducting the research, the principles of the Declaration of Helsinki, the general guidelines for ethics in research with human subjects and the regulations governing it were observed and the code of ethics was issued by the ethics committee of Lorestan University.
Findings: Insomnia did not lead to a significant difference between the blood sugar and insulin levels of athletes and non-athletes when faced with a (p≤0.05). Also, insomnia did not cause a significant difference in the amount of cortisol between two groups of athletes and non-athletes (p≤0.05). Conclusion: It seems that changes in blood sugar, cortisol and insulin are related to the duration of insomnia and are not affected in short-term and intermittent insomnia.

Keywords: Insomnia, blood sugar, cortisol, insulin, athlete, non-athlete
 

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Backgrand: Inflammation can cause damage to the central nervous system, leading to neuropathological diseases such as stroke, pain, schizophrenia, and Alzheimers. AIM2 is a member of the PYHIN hematopoietic nuclear protein family that binds to cytosolic DNA and activates caspase-1, one of the inflammatory-mediated caspases that activates pro-inflammatory cytokines. The aim of this research is to investigate the effect of a swimming training course on the expression of caspase-1 and AIM2 proteins in the hippocampus of male Wistar rats.
Method: The statistical population of this study included 16 male Wistar rats (6 weeks) divided into two groups: a group without training and an endurance training group. Eight rats were placed in each group. The group without training did not engage in any sports activities, while the training group participated in a swimming training session. After a 4-day familiarization period, the rats swam for 30 minutes from the fifth day. Independent T-test was used to evaluate the interventions, and all statistical calculations were done using SPSS statistical software.
Results: The results of this research showed that exercise caused a significant decrease in the level of caspase-1 and AIM2 proteins in the hippocampus of male Wistar rats.
Discussion: Overall, this study suggests that endurance swimming training can effectively reduce caspase-1 and AIM2 proteins. Therefore, it is possible that exercise, by reducing inflammatory factors, can be a potential treatment for diseases caused by inflammation, such as sclerosis, diabetes, cancer, and Alzheimers.
 

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Abstract
Introduction: Resistance training (RT) is an important part of athletes' preparation exercises with the aim of strengthening physical fitness, creating neuro-muscular adaptations and improving sports performance. The aim of this study was to investigate the effect of resistance training with weight on NCV of tibial and peroneal nerves, muscle strength, agility, flexibility and performance of half-back, half-turn and angel balance skills in seven- to ten-year-old gymnasts.
Methods: In this semi-experimental study, 24 children with two years of experience in gymnastics (age: 8.5±1.5 years, weight: 32.10±9.40 kg, height: 135±13 cm) voluntarily Participated. Subjects were randomly divided into two groups including gymnastics training and gymnastics training + resistance training with weights. And they trained for 10 weeks. During the research, one group did general gymnastics exercises, and the other group did resistance training with weights three times a week in addition to gymnastics exercises. Before and after the exercises, NCV test, Sargent's jump muscle power tests, agility of 9x4m back-and-forth run, Wells' flexibility, and performing half-back, half-turn and balance skills of Angel were performed. Independent t-test was used to analyze the data. And a significance level of P<0.05 was considered.
Results: The results showed that the NCV in the tibial and peroneal nerves increased significantly in the weight resistance training group compared to the general gymnastics training group. Also, muscle strength in Sargent's jump, agility in 4x9m back and forth running, and the performance of half-back and half-turn skills increased significantly (P<0.05). However, no significant change was observed in the flexibility with the Wells test (P=0.870) and execution of Angel's balance skill (P=0.552).
conclusion: 10 weeks of resistance training with weights significantly increases neuromuscular adaptations, NCV, muscle power, agility, and implementation of half-back and half-varus skills in gymnast children. Therefore, it is suggested to use resistance exercises with weights to improve the performance of children athletes in the field of gymnastics and fields where nerve conduction speed, muscle power and agility are effective in the success of athletes.

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Introduction: Traffic accidents are a principal challenge in the injury and death of people in Iran and many other countries, which has made the formulation of necessary strategies and planning for inter-sectoral cooperation to prevent and reduce traffic accidents undeniable. Therefore, this research was conducted to investigate the dimensions of inter-sectoral collaboration in preventing traffic accidents in Iran.
Methods: This research is a qualitative study that was conducted in 2023. In this study, sampling was done in a targeted manner, and 15 people from the statistical population were interviewed. The statistical population of the research at this stage included executive managers, traffic police, field activists, and public institutions active in the field of traffic accidents in Central Province and Tehran, who, due to the relevance of their job field, were informed or participated in intersectoral cooperation in line with the management of accidents and traffic accidents were included in the study. Data were collected and analyzed through structured interviews, and their coding was done with the help of MAXQDA 11 software.
Results: The study identified and extracted eight main dimensions of intersectoral cooperation in preventing traffic accidents. These dimensions include laws and law enforcement, research and development, information and data management, internal and external coordination, crisis management, education and awareness, roads, and vehicles.
Conclusions: Providing platforms for promoting the development and expansion of inter-sectoral cooperation in accident prevention and traffic accidents can have various benefits, including long-term social, political, economic and, well-being. Therefore, based on the findings of the research, it is suggested to design an intersectoral cooperation model for the prevention of accidents and traffic accidents so that traffic accidents can be reduced to the minimum possible with proper planning and design so that we can witness the highest level of effectiveness and efficiency in this area.

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Introduction: Physical activity positively influences various physiological factors, laying the groundwork for beneficial changes. Myostatin and follistatin are among these factors, whose levels are influenced by gender and physical activity. The present study was conducted with the aim of investigating the effect of traditional resistance training (RT) and high functional training (HIFT) on the serum levels of myostatin and follistatin in young women.
Methods: In this semi-experimental study, 30 young women were selected and divided into three groups: intense functional training, traditional resistance training, and control. Blood was drawn 24 hours before and 48 hours after the end of the interventions to measure the serum levels of myostatin and follistatin. The exercise protocols were performed for eight weeks, 3 days a week and 60 minutes a day. Ultimately, the collected data were analyzed using the ANOVA statistical method, with a significance level set at P < 0.05.
Results: The results showed that follistatin level was significantly higher in the RT and HIFT groups than in the control group (P = 0.001). Also, the amount of follistatin in the HIFT group was considerably higher than the RT group (P = 0.01). The results showed that the level of myostatin in the RT and HIFT groups was significantly lower than the control group (P = 0.001). Also, the amount of this factor in the HIFT group was substantially lower than in the RT group (P = 0.01).
Conclusions: In general, the findings of the present study show that performing intense resistance and functional exercises causes a favorable change in the expression of physiological factors related to muscle growth in women. It seems that the effect of intense functional exercises is greater than resistance exercises.

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Introduction: Diabetic foot ulcer is the most common cause of hospitalization in diabetic people, while one of the prominent sources of anxiety in patients is the time of discharge from the hospital. This study aimed to determine the effect of the SMART discharge protocol on the anxiety of diabetic foot ulcer patients.
Methods: In this semi-experimental study, 50 patients with diabetic foot ulcers Were divided equally into two control (25 patients) and intervention (25 patients) groups, randomly and based on the Inclusion criteria. In the intervention group, the SMART discharge protocol was implemented from their admission to the day of discharge. The Demographic information questionnaire and Spielberger questionnaire were used to determine patients' anxiety. The data were analyzed at two descriptive and inferential levels.
Results: There was no statistically significant difference in the mean score of anxiety for diabetic foot ulcer patients in the two groups before the intervention. In contrast, after the intervention, the mean anxiety score in the two groups showed a statistically significant difference (P = 0.0001).
Conclusions: According to the results of the present study, it seems that the smart discharge protocol was effective in reducing the anxiety of diabetic foot ulcer patients. Therefore, it is recommended that nursing officials and managers implement this protocol.