---

---

Background and Aim: Food restriction (FR) affects on depression and anxiety behavior. Previous studies have pointed to the role of sulpiride in the treatment of depression and anxiety. The purpose of this study was to determine the role of dopaminergic system and food restriction on depression and anxiety. Materials and Methods: Forty two adult male Wistar rats (180-220g) were divided into 7 groups including: control, sham, 25%, 50%, 75% FR, 75% FR with sulpiride and sulpiride(50µg/rat). The treatment period was 21 days. Day 19 surgery and cannulation was performed and Sulpiride was injected intracrebroventricularly (icv) on the 21st day. Depression and anxiety tests (Tail suspension test and Elevated Plus Maze), was taken from the rats on the 21st day. Data were analyzed by ANOVA test. Ethical Considerations: Ethical points were observed according to the declaration of Helsinki and acts of Bioethics Committee at Urmia University (Ref No: AECVU-180-2018). Findings: Mobility time in FR groups and sulpiride compared to control and in 75% with sulpiride compared to 75% had significant increase. immobility time in FR and sulpiride had significant decrease compared to control. Open arm entry in 75% FR had significantly decreased compared to control and in 75% FR with sulpiride had significantly increased compared to 75%. Open arm spend time in 75% FR with sulpiride had significant increase compared to 75%. Motor activity was reduced in FR groups and injection sulpiride. Conclusion: It seems that sulpride and FR play a role in improving semi-depression circumstances. Sulpiride also play a role in controlling the anxiety behavior induced by FR.

---

---

---

---

Background and Aim Apoptosis or programmed death is active biological process and reversible that the balance between growth and cell death in various tissues, particularly myocardial tissue is essential role. The aim of this study was the effect of 8 weeks High Intensity Interval Training (HIIT) with and without food restriction on gene expression of Caspase 3 and 9 in rats.
Methods & Materials: This study was experimental multi group design with control group which conducted on 30 rats with two months old male. Subjects were divided in to five homogenous groups including base control, control, caloric restriction, interval exercise training and caloric restriction+interval exercise training. Training groups five sessions in weeks were participated in interval exercise training for 8 weeks. The level of gene expression of the proteins Caspase 3 and 9 was evaluated by Real Time-PCR. Dates were analyzed using the 1-way ANOVA at the level of (P<0.05).
Ethical Considerations: The protocol of this study was approved by the Medical Committee of Sanandaj University of Medical Sciences (Code: IR.MYK.REC.1397.5022).
Results: The results showed that the training group had a significant decrease in gene expression of Caspase 3 in comparison with caloric restriction+exercise training (P<0.05). Also, exercise training and exercise training+caloric restriction significantly decrease in the gene expression of Caspase 9 compared to caloric restriction, base control and control (P<0.05) and significantly decrease in the gene expression of Caspase 3 compared to base control and control (P<0.05).
Conclusion: According to the results, it seems that high intensity interval training with and without calorie restriction provides the necessary adaptations to inhibit or stop apoptosis induced by aerobic exercise. 

---

---

---

Background and Aim: The purpose of this study was to determine the effectiveness of mindfulness-based cognitive therapy on marital self-regulation, marital burnout, and self-criticism of infertile women.
Methods & Materials: This experimental study was conducted with a pretest-posttest design with the control group. The statistical population of this study included all the infertile women of Mazandaran Province, Iran, in 2018-2019. In this study, 30 infertile women were considered the sample size in the experimental group mindfulness-based cognitive therapy (of 15 infertile women) and control (15 infertile women). The experimental group underwent mindfulness-based cognitive therapy (10 sessions 60 minutes), but the control group received no training. To collect data, we used the marital self-regulation scale of Wilson and et al., the marital burnout scale of Pines, and the self-criticism scale of Thompson and Zuroff. Data analysis was performed in SPSS V. 24 with descriptive and inferential statistics (multivariable analysis of covariance).
Ethical Considerations: This study with research ethical code IR.IAU.TON.REC.1397.030 was approved by the Research Ethics Committee at Islamic Azad University Tonekabon Branch.
Results: The results showed that the scores of marital self-regulation of infertile women after mindfulness-based cognitive therapy in the experimental group significantly increased in comparison with the control group, and also marital burnout, and self-criticism scores were decreased (P<0.01).
Conclusion: Therefore, it is suggested that counselors and therapists use mindfulness-based cognitive therapy to improve marital self-regulation, marital burnout, and self-criticism of infertile women. 

---

---

---

Background and Aim: The development of any society depends on the educational system of that society. The educational system can be efficient and successful when considering the academic performance of learners in different courses. This study aimed to investigate the effects of mental self-care education on students’ mental health and academic motivation.
Methods & Materials: This was a quasi-experimental study with unequal control and experimental groups. The statistical population of this study was students referring to school counseling centers; 40 of them (n=20/group) were selected by random sampling method. The Depression, Anxiety, and Stress Scale - 21 Items (DASS-21), and Academic Performance Rating Scale were used to collect the necessary data. Psychological self-care training was presented to the experimental group in ten 2-hour sessions. Then, a posttest was conducted on the study groups. Data analysis was performed using Multivariate Analysis of Covariance (MANCOVA).
Ethical Considerations: This article was approved by the Ethics Committee of the Islamic Azad University, Khomeini Branch (Code: IR.IAU.ARAK.REC.1399.001).
Results: The obtained findings indicated that mental self-care education was effective on students’ mental health (P<0.05). Furthermore, psychological self-care education was ineffective on students’ academic motivation.
Conclusion: Mental self-care education was used to improve mental health; however, this training did not affect academic motivation in the examined subjects.

---

Background and Aim:  It is almost impossible to imagine life without electromagnetic waves. Such waves play a key role in the function of melatonin and create numerous diseases. 
Methods & Materials: This descriptive-analytical study was conducted on 230 kV substations in Golestan Province, Iran in 2016. In total, 44 workers of electrical substations (the case group) and 23 workers of healthcare centers (the control group) with 24-hour shift works were enrolled in this study.
Ethical Considerations: This  study was approved by the Ethics Committee of Shahid Beheshti University Medical Sciences( Code: IR.SBMU.THNS.REC.1395.9). 
Results: The obtained data suggested that 100% of the electric field intensity and the magnetic flux density measured at the substations were within the permissible range of occupational exposure. The mean level of melatonin in the case group was lower than that in the control group; however, no significant difference was observed in this regard (P=0.761). Additionally, there was no significant difference between melatonin level and age (P=0.381), work experience (P=0.213), job groups (P=0.515), and employee activity area (P=0.482).
Conclusion: According to this study, no significant relationship was observed between electromagnetic waves and melatonin levels. Moreover, electromagnetic waves were within the permissible exposure. Thus, electromagnetic waves did not affect the level of melatonin hormone in male employees of 230 kV substations in Golestan Province. However, there was a decrease in the case group, compared to the controls. Therefore, definite comments require further investigation.

---

Background and Aim: Considering the increasing use of dental implants in replacing lost teeth, the odds of failure over time in this treatment are inevitable, as with other dental treatments; thus, it requires careful and regular follow-up. Accordingly, the present study aimed to evaluate the awareness and attitude of general dentists about the follow-up of the dental implants to create baseline information to schedule future workshops concerning dental implants.
Methods & Materials: In this analytic cross-sectional study, 98 general dentists of Arak City, Iran were evaluated. Questionnaires were designed in 3 sections, as follows: demographic, awareness, and attitude. After checking the validity and reliability of the questionnaires, they were distributed among the research participants. The obtained data were analyzed using descriptive analysis, Chi-squared test, and Independent Samples t-tests. The significance level was considered 0.05.
Ethical Considerations: This article was approved by the Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.283).
Results: The average score of awareness of the questionnaires was equal to 10.8 (based on the score of 0-19); the mean score of attitude was measured as 12.8 (based on the score of 7-21). Fifty-Three of the explored dentists had performed implant treatment, whose awareness and attitude toward implants follow-up were significantly higher than those of the dentists who did not perform such treatment (P=0.0001). Work experience presented no significant effect on the examined dentists’ awareness and attitude (P>0.05).
Conclusion: General dentists have low awareness and attitude about implant follow-up. Follow-up plays an important role in the long-term success of implant therapy; therefore, dental education/retraining programs should be reviewed in this field.

---

Background and Aim: Needlestick injury (NSJ) is a common occupational health problem among dental healthcare workers, putting them at significant risk for blood-borne infections. This study aimed to investigate occupational exposure to NSJ and the psychological factors associated with it among dentistry students.
Methods & Materials: This descriptive cross-sectional study was carried out on students in the Arak school of dentistry training curriculum in the last three years in 2018. The questionnaires included questions about students’ awareness of NSJ conditions, the frequency of vaccinations, and antibody titration tests. The SCL-90 (Symptom checklist-90) questionnaire assessed psychological factors after NSJ in four dimensions of anxiety, phobia, self-morbidity, and depression. Data analysis was performed using descriptive statistical methods and a chi-square test.
Ethical Considerations: The study was approved by the Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.269).
Results: Of the eighty students surveyed, 59 students had experienced NSJ at least once. However, only 25.4% of students had reported the NSJ occurrence. The highest incidence rate of NSJ was reported in the endodontics section. In addition, 80% of students had received hepatitis B vaccinations. Based on the SCL-90 test, the anxiety dimension was more affected by NSJ than the other dimensions.
Conclusion: Despite the high prevalence of NSJ in dental students, the rate of reporting after the accident is very low. Also, due to the lack of attention to vaccination in some students, there is a need for more infection control training. Based on the SCL-90 test, the occurrence of NS is effective in causing psychological problems.

---

Background and Aim: Acquisition skill in sentence producing is one of the criteria for speech development. By developing and increasing the age, we are witnessing the emergence of compound sentences in speech. Clinical treatments for language disorders in Iran are mostly based on the experiences of Speech Language Therapists or in accordance with English language norms. We need to examine how the length of utterance and compound sentences develop in Persian. The study aimed to report the development of compound sentences and Mean Length of Utterance (MLU) for a Persian-speaking child from 15 to 34 months.
Methods & Materials: In this longitudinal case report, based on Developmental-Descriptive model, MLU and emergence of simple compound sentences of a Persian speaking girl sampled and described from 15 to 34 months by daily scripting. R software version 4.0.2 was used for data analysis. Correlation of age with linguistic variables through Pearson correlation coefficient was evaluated. 
Ethical Considerations: In this paper, the principles of publication ethics were considered.
Results: At the age of 21 months and 13 days, the child uttered her first simple two-word sentence, and at the age of 26 months and 29 days, she used a four-word compound sentence. With the emergence of compound sentences, the increase in the MLU has gained considerable speed. In a few days, we see the addition of a unit to the length of the sentence (word). There was a significant relationship between the MLU and age (r=‌0.925, P=‌0.001), Mean length of sentence and number of words in Persian speaking child (r‌=‌0.910, P=‌0.002) and total number of words and age (r‌=‌0.928, P<0.001). 
Conclusion: Although several longitudinal studies have been conducted on the development of MLU and number of words in other languages, similar studies are rare in Persian. It is important to conduct studies of this type in order to make cross-linguistic comparisons and to study the linguistic universality and language specificity. By increasing age, we see an increase in the number of words in a child's vocabulary, the emergence of compound sentences, and an increase MLU. At 27 to 28 months, there is a dramatic change in the development expressive language as the compound sentences appear. It seems that emergence of compound sentences in the language output, also plays a significant role in increasing the MLU and can be considered in clinical language assessments.

---

Background and Aim: The World Health Organization has recently identified COVID-19 as a pandemic. The outbreak of the disease has caused many people around the world to become extremely frightened and they show phobic signs. The purpose of the present study was to develop and normalize of Germophobia Questionnaire (GPQ).
Methods & Materials: The participants were 113 individuals (74-female) of the Iranian population. They completed the GPQ and Y-BOCS.
Ethical Considerations: All ethical principles and privacy policies of the results informed the participants. This study was approved in the second session of the Psychological Committee of the Islamic Azad University of Tehran’s province in March 2020.
Results: The results illustrate that the GPQ has acceptable internal consistency with Cronbach’s alpha coefficient (a=0.67), reliability coefficients with split-half (0.72), and one-week test-retest (r=0.73); in addition, the GPQ demonstrate moderate convergent validity with contamination obsessions checklist of Y-BOCS (r=0.44) as a convergent coefficient; and finally, the exploratory factor analysis indicates three-factors of the GPQ. 
Conclusion: Based on these findings, the GPQ has acceptable and good psychometric properties; researchers can use the GPQ as a reliable and valid instrument for assessing the germophobia levels in epidemic and pandemic crises like COVID-19.

---

Background and Aim: A common infection in complete or partial denture wearers is denture stomatitis. One of the most important factors in the adhesion of Candida albicans is the surface and chemical properties of the denture base materials. The aim of this study was to investigate the surface roughness and adhesion of Candida albicans to two different types of acrylic materials.
Materials and Methods: In this experimental study, 16 samples were prepared from each of Vertex and Ivoclar acrylic resin. The surface roughness of the samples was measured by a profilometer. The samples were then placed in a cell suspension of Candida albicans. After incubation and staining with acridine orange, the yeast cells attached to the acrylic samples were counted using a fluorescent microscope. Data were statistically analyzed by T-test.
Ethical considerations: This article is approved by the ethics committee of Arak University of Medical Sciences with the ethics code: IR.ARAKMU.REC.1398.301.
Findings: There was no statistically significant difference in the mean of surface roughness between the two study groups (P = 0.311). However, Candida albicans colonization in ivoclar acrylic was significantly lower than vertex acrylic. (P = 0.000).
Conclusion: Differences in surface topography and physical and chemical properties of Vertex and Ivoclar acrylic resin affect the adhesion of Candida albicans.

---

Background:  Rotator cuff injuries are one of the most common causes of shoulder pain.
There are different therapeutic approaches in this disease. The evidence of the positive effect of exercise therapy in this pathology is inconclusive. This study aimed to investigate the effect of a complete exercise protocol on improvement of the patients with rotator cuff injuries.
Methods: The patients with shoulder pain received the 12-week exercise protocol in 4 phases if they had confirmed rotator cuff injuries in clinical examination and shoulder MRI. 
Pain was measured by visual analog scale (VAS) and function was measured by two questionnaires; disabilities of the arm, shoulder and hand (DASH) and western Ontario rotator cuff index (WORC). Range of shoulder joint motion (ROM) was measured in five directions by goniometry. All of the outcomes were evaluated before intervention and in 6, 12, 24 weeks after starting the intervention.
Ethic: This study was registered in Iranian Registry of Clinical Trials (IRCT20100718004409N13). A written consent was taken from All participants before the study. 
Results: In this study Twenty-four patients with rotator cuff tendinopathy and tear were analyzed finally in terms of effectiveness of exercise therapy. The average of their age was 51.7 years old. 14 patients (53.8%) with Supraspinatus tendinopathy, 6 patients (23%) with Supraspinatus tear, 3 patients (12.5%) with Supraspinatus plus biceps tendinopathy, and one patient (4.16%) with Subscapularis plus Biceps tendinopathy were assessed. The pain score (Visual Analog Scale) decreased at all fallow-ups specially after 24 weeks (3±0.1) versus before intervention (8±0.1) (P value < 0.001). Shoulder range of motions by goniometer and also the patients function based on WORC and DASH Questionnaires were improved after 24 weeks versus before intervention that was significant statistically and clinically (P value < 0.001). 
Conclusion: A 12- week exercise protocol including strengthening, stretching, PNF and dynamic stabilizer exercises was effective on pain reduction and improvement of function and shoulder joint range of motion improvement in the patients with shoulder rotator cuff tendinopathy and partial tear. The improvement of the variables lasted 6 months.
 

---

Background and Aim: Different implant angulation, which is unavoidable in clinical situations, can affect the accuracy of impression. The aim of this study was to investigate the effect of fixture position on the accuracy of connecting impression coping to implants with internal hex.
Materials and Methods: A gypsum model with 4 implants with internal hex connection was prepared. The implants were installed in different mesiodistal angles of 0, 15, 25 and 35 degrees to the longitudinal axis in the gypsum model. To simulate the gums, a gingival mask was injected around the implants to a height of 2 mm. After a training session for senior dental students on how to close the impression coping, forty students were asked to close the impression copings on four implants. The correctness of the impression coping was evaluated by an expert prosthodontist. Data were statistically analyzed using Cochran Q test. Significance level was considered 0.05.
Ethical Considerations: this article is approved by ethics committee of Arak University of Medical Sciences.
Findings: The correct performance of students in connecting the impression coping to the implant at angles of 0, 15, 25 and 35 degrees was equal to 85%, 72%, 52%, 35%, respectively. With the exception of 0 and 15 degree groups, a statistically significant difference was observed between different study groups.
Conclusion: The fixture position has a significant effect on the accuracy of connecting impression coping to the implants with the internal hex and by increasing the implant angulation, the accurate connection the impression coping to the implant decreases.