Showing 23 results for Miri
Fereshteh Narenji, Nasrin Rozbahani, Leila Amiri,
Volume 12, Issue 4 (Research in Education Supplement 2010)
Abstract
Abstract Background: Study of the nursing and midwifery instructors and students viewpoints, as two important groups in teaching proccess, can be effect on codifying and evaluating of educational program and effectiveness in this courses. The purpose of this study was to determine the effective educational and evaluation program on clinical learning from the nursing and midwifery instructors and students’ opinion in Arak University of Medical Sciences, 2008. Materials and Methods: In a descriptive study in 2008, all students and clinical lecturer (n=84) were studied. The data gathering tool was a questionnaire consisted of three parts, demographic information, clinical education and evaluation program. Results: The age mean of the teachers and students respectively were 38±3.14, 22.2±2.18 years and the mean of theoretical and clinical history teaching of instructors, respectively, were 6.04±2.48 and 10./95±2.9 years. The most percents of instructors (91.3%) emphasized on considering the communicating skills education in education program. The most percents of students (85.2%) emphasized on considering the critical thinking and moral students support. Also, the most percents of instructors (78.3%) emphasized on step by step evaluation. While, the most percents of students (90.2%) emphasized on the effect of teachers evaluation and reflected the results to them. Conclusion: Hope to, this study results can be helpful to effective nursing and midwifery students’ lesson planning and evaluating.
Tooba Heidari, Noorolsadat Kariman, Zahra Heidari, Laila Amirifarahani,
Volume 12, Issue 4 (Research in Education Supplement 2010)
Abstract
Abstract Background: Different studies have shown the inability of traditional lecture method to active teaching method in concept transmitting of higher learning domain. The aim of this study was comparing the effects of feedback lecture method and conventional lecture method on learning and quality of teaching. Materials and Methods: In quasi-experimental study, 27 Arak medical science midwifery students who were in fourth semester, randomly, were divided to two groups of “teaching by feedback lecture” and “teaching by conventional lecture”. Desired topic were presented by one teacher as a 90- minute lecture in control group and as two 35-minute lectures with 10-minute discussion after each part in case group. Informational form, and post test and student' opinion form were used respectively to identify the demographic characteristics, short tem and long term learning and quality of teaching form. Results: Demographic characteristics, quality of teaching form student’s opinion, total scores of pre and post test were similar in two groups. Results of teaching score in post test in knowledge and perception level were similar. But there was a significant difference between application and analysis level in two groups(p=0.011). Also, total and domain scores of post test after a month were not different in both groups. Conclusion: Results indicated that learning by feedback lecture can be more effective than conventional lecture method in application and analysis domain.
Mohammad Gholami Fesharaki, Davood Talebian, Zohreh Aghamiri, Masome Mohamadian,
Volume 14, Issue 5 (11-2011)
Abstract
Background: This study was done to assess the validity and reliability of Najmie Job Satisfaction Questionnaire (NJSQ) in order to provide a suitable tool for measuring job satisfaction (JS).
Materials and Methods: In this cross-sectional study, 212 staff members at Najime Subspecialty Hospital were selected by stratified sampling method. The participants took NJSQ. After evaluating content validity, confirmatory and explanatory factor analysis and Cronbach's Alpha were used to examine construct validity and reliability of the questionnaire, respectively. SPSS software version 16 was used to analyze the data.
Results: The samples, 212 subjects, consisted of 181 (86.6%) women and 28 (13.4%) men. The explanatory factor analysis showed 4 factors with 54% total variance and 0.82% Kaser-Meyer-Olkin index. These factors were also verified by confirmatory factor analysis (P=0.368). In addition, the reliability of the questionnaire was reported to be 0.88% based on Cronbach's alpha method.
Conclusion: Since validity and reliability indexes were reported suitable, NJSQ can be considered a valid and reliable questionnaire for measuring JS.
Leila Amiri Farahani, Tooba Heidari, Nasrin Roozbahani, Mahtab Attarha, Naeime Akbari Torkestani, Reza Bekhradi, Vida Siyanaki,
Volume 15, Issue 4 (September 2012)
Abstract
Background: Dysmenorrhea is a common problem in women of reproductive age and despite the current treatments, it still remains a common problem in women’s health. This study was done to determine the effect of aromatherapy on pain severity in primary dysmenorrhea. Materials and Methods: This randomized clinical trial was done on 108 students with primary dysmenorrhea with pain score of 2 and 3 based on the multidimensional spoken criteria. After random allocation, the participants received massage with almond oil, massage alone, and massage with a mixture of lavender and peppermint essential oil a week before menstrual period until the presence of pain in two continuous cycles. During cycles zero, one, and two, the participants recorded the highest level of pain during the first, second, and third days according to the visual analogue scale. Data were analyzed using SPSS software. Results: There was a significant difference in the total of the most pain in days 1, 2, and 3 among the groups(p=0.038). A reduction was observed in massage and aromatherapy groups(p=0.014). There were significant differences in within group comparisons (p=0.002) for zero and first cycles(p=0.016) and first and second cycles(p=0.002). Conclusion: Aromatherapy reduces menstrual pain and considering the prevalence of dysmenorrheal, the low price, and harmless nature of this essence, its application in relieving menstrual cramping and pain is recommended.
Naimeh Akbari Torkestani, Mahtab Atarha, Tooba Heidari, Leila Amiri Farahani, Nasrin Roozbehani,
Volume 16, Issue 5 (8-2013)
Abstract
Background: Depression is one of the most common problems in postmenopausal women. Diosgenin present in fenugreek seeds present study the effects of menopause on depression in menopausal women took the city in 1390.
Materials and Methods: In a randomized controlled trial enrolled 60 women with complaints of depression caused by menopause. Beck Depression Inventory on a sample of postmenopausal women and the inclusion criteria were enrolled. The samples were divided randomly into two groups, Diosgenin (6 g Fenugreek seed daily containing 25 mg Diosgenin) and sorbitol (25 mg daily) for 8 weeks were placed before and after 8 weeks of intervention questionnaire, Beck completed SPSS software was used to test the statistical Paired test scores before and after treatment were compared.
Results: Mean depression score decreased after 8 weeks took Fenugreek containing Diosgenin and sorbitol as compared with before of intervention of this study and it was significant.The comparison did not indicate a significant difference between the two groups.
Conclusion: According to the finding of this study, administration of 6 g Fenugreek seed containing Diosgenin for 8 weeks decreased menopausal depression . The need for further studies with longer duration and higher doses before any recommendations can be felt.
Fatemeh Dorreh, Parsa Yousefi, Javad Javaheri, Babak Eshrati, Zahra Amiri,
Volume 16, Issue 8 (11-2013)
Abstract
background: Early detection and treatment are crucial to prevent mental retardation in congenital Hypothyroidism (CH). The aim of this study was to evaluating of screening program of CH in Markazi Province.
Materials and Methods: In cross sectional descriptive study we used recorded data in Markazi province health center. From 2006 to 2012,127112 newborns were screened by measurement of serum TSH level by heel prick. Neonates who had blood TSH&ge5MIU/L were recalled for more evaluation. Neonates with confirmed hypothyroidism underwent treatment.
Results: From127112 screened neonates, 414 were diagnosed as CH patients (both permanent and transient). The prevalence of CH was . Recall rate was 4.8%. In 94.4% of patients, treatment were begun before the 40th day of life. The coverage percent in the province was 100% from the second year of the program.
Conclusion: Recall rate and the incidence of CH were higher than those in other studies, both in Iran and other countries. The mean age of treatment initiation and coverage percent were in favorable range.
Homa Mohseni Kouchesfahani, Khadije Sanamiri, Mahmoud Hashemitabar,
Volume 17, Issue 4 (7-2014)
Abstract
Background: Wharton's Jelly Mesenchymal Stem Cells (WJMSc) are potential renewable source of cells in replacement therapies of many diseases. Different biomaterials have been used as a scaffold to mimic the stem cell niche, which is important for promoting cellular interactions, cell proliferation and differentiation. Encapsulation involves entrapment of living cells within the semi-permeable membrane for the exchange of nutrients, oxygen and stimuli, whereas antibodies and host immune cells are kept out. In this study, a new approach for culturing and differentiating Wharton's Jelly Mesenchymal Stem Cells to definitive endoderm in a three dimensional environment using alginate capsules is presented.
Materials and Methods: In this experimental study, Wharton's Jelly Mesenchymal Stem Cells were capsulated and Trypan blue exclusion method was applied to determine cells viability. Then, encapsulated cells have been cultured in medium contain differentiating factors and to investigate the expression of definitive endoderm related genes, Real- time PCR was performed.
Results: The encapsulation procedure did not alter the morphology and viability of the encapsulated cells. Post-differentiation analysis confirmed the expression of FOXa2 and SOX17 as definitive endoderm specific markers.
Conclusion: Alginate has potential to be used as a three dimensional scaffold for culturing and differentiation of WJMSCs to definitive endoderm.
Mehdi Hooshmandi, Narges Hosseinmardi, Mahyar Janahmadi, Fereshteh Motamedi, Azadeh Elahi Mahani, Fatemeh Sadat Aghamiri,
Volume 17, Issue 6 (9-2014)
Abstract
Background: Considering the increased activity of hypothalamic orexinergic neurons due to morphine administration, and its extensive projections to the hippocampus, it is probable that morphine effect on CA1 neuronal function is mediated by orexinergic system. So the effect of hippocampal orexin-1 receptors (OX1R) blockade on CA1 baseline synaptic response and short term synaptic plasticity was investigated.
Materials and Methods: In this experimental study, animals received morphine 10 mg/kg/12h/(SC) for 10 days. SB-334867-A, OX1R antagonist (0.5&mug/0.5 &mul), was microinjected intrahippcampally for OX1R inhibition before each morphine injection. Baseline synaptic response and short term synaptic plasticity were evaluated by field potential recording. fEPSP was recorded from CA1 following Schaffer collaterals stimulation. After Input/Output construction, short term synaptic plasticity was induced by paired pulse stimulations.
Results: Chronic use of morphine did not affect the baseline synaptic response (p>0.05). SB- 334867-A microinjection in CA1 did not have any effect on baseline synaptic response in morphine dependent rats. Morphine increased paired pulse index (PPI) at 80 ms inter pulse interval (IPI, p<0.05). SB-334867-A pretreatment did not affect this morphine induced PPI change.
Conclusion: The results suggest that orexin-1 receptors (OX1R) do not mediate the effect of morphine on baseline synaptic response and short term synaptic plasticity in CA1 area of the hippocampus.
Mohammad Mosleh Abadi Farahani, Naser Amirizadeh, Arezoo Odi, Mona Khorshidfar, Mahin Nikougoftar Zarif,
Volume 17, Issue 7 (10-2014)
Abstract
Background: Hematopoietic stem cell transplants are routinely used to treat patients with cancers and other disorders of blood and immune systems. Osteoblasts constitute part of the stromal cell support system in marrow for hematopoiesis by participating in the formation of the HSC niche. It is believed that interaction between hematopoietic cells and bone forming osteoblasts regulate each other’s function. It is established that acute blood loss in animal models activates bone formation and niche development because of EPO stimulation. In this experimental study we have examined the co-culture of HSCs derived from cord blood which treated with EPO in vitro, on osteoblastic differentiation of mesenchymal stem cells.
Materials and Methods: In this experimental study MSCs isolated from bone marrow and co-cultured with CD 34+ CD38- HSCs isolated from cord blood. These co-cultured cells were treated with different doses of erythropoietin for 14 days, after that RNA were extracted from MSCs and analysed with RT-PCR to evaluate the expression of osteopontin and osteocalcin. Alizarin red and alkaline phosphatase staining were done for osteoblastic differentiation.
Results: Osteopontin and osteocalcin were expressed in MSCs. Cellular staining were positive for osteoblastic differentiation. Differentiated cells expressed osteoblastic markers.
Conclusion: These data suggest that EPO regulates the osteoblastic differentiation from bone marrow MSCs in vitro.
Fatemeh Sadat Seyedaghamiri, Narges Hosseinmardi, Mahyar Janahmadi, Azadeh Elahi Mahani,
Volume 18, Issue 9 (12-2015)
Abstract
Background: Considering the increased activity of hippocampal glial cells due to chronic morphine administration and the involvement of hippocampus in restoration of the addictive drug-associated experience, the role of these cells on morphine induced conditioned place preference (CPP) was investigated.
Materials and Methods: In this experimental study, four groups of animals were evaluated. After habituation to CPP apparatus on the first day, conditioning was done by injection of morphine (5 mg/kg) or its vehicle (saline) during three consecutive days. On the fifth day, the time spent in each compartment of CPP cage and locomotor activity was recorded for 20 min. To investigate the role of hippocampal glial cells in CPP, these cels were inbibited by bilaterally injecting fluorocitrate (1nmol/1ml), before each morphine injection. CPP testing in this group and animals received fluorocitrate vehicle (Phosphate buffer saline) was done before morphine injection.
Results: Fluorocitrate pretreatment reduced morphine induced conditioned place preference acquisition, so that a significant decrease was observed in conditioning score (unpaired t-test, p<0.01) in this group (n=8) compared to animals received morphine (n=9). Neither morphine nor fluorocitrate pretreatment did not affect locomotor activity (ANOVA, p>0.05).
Conclusion: The results suggest that glial cells in the hippocampus are involved in morphine induced conditioned place preference.
Majid Amiri Motlagh, Mohammad Ali Atlasi, Zeinab Vahidinia, Sayyed Alireza Talaei, Zeinab Rezazadeh Lavaf, Abolfazl Azami Tameh,
Volume 20, Issue 5 (8-2017)
Abstract
Abstract
Background: Glutamate is the most widespread excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays major role in the pathogenesis of ischemia brain injury.Glutamate transporters have a major role in glutamate removal and maintain its concentration below excitotoxic levels. Although estrogen’s and progesterone’s neuroprotective effects were well-described, the exact molecular mechanism has yet to be determined. This study has investigated estrogen and progesterone effect on glutamate transporters expression in the ischemic penumbra/peri-infarct region in rat.
Materials and Methods: Adult male Wistar rats were subjected to transient middle cerebral artery occlusion (tMCAO) for 1 h. Estrogen and progesterone combination was immediately injected after tMCAO subcutaneously. Sensorimotor functional tests for evaluating behavioral deficits and TTC staining for measurement of infarct volume were performed 24 h after MCAO. Real-time PCR technique was used for gene expression analysis of glutamate transporters EAAT2 and EAAT3.
Results: The combination of estrogen and progesterone could significantly reduce lesion volume. Also, hormone therapy could improve ischemic neurological disorders. After hormone therapy, gene expression of glutamate transporters EAAT2 and EAAT3 did not show significant changes.
Conclusion: Combined estrogen–progesterone treatment significantly reduces neurological deficits and infarct volume; these effects are independent of the glutamate transporters signaling pathways.
Rasoul Najafi, Fatemeh Amiri, Ghodratoalleh Roshanaei, Mohammad Abbasi,
Volume 22, Issue 2 (6-2019)
Abstract
Background and Aim: Colon cancer is one of the most common cancers in the gastrointestinal tract. Colon cancer is the third death cause among cancers. The aim of this study was to estimate the survival rate and determine the effective factors in colon cancer patients.
Materials and Methods: In this study, 193 colon cancer patients referring to Hamadan Imam Khomeini Clinic during the years 2003-2017 in a retrospective cohort study were used. Follow up of all patients was done by referral and phone call up to 2017. The Kaplan -Meyer model was used to estimate the survival of patients. Also, the effect of prognostic factors on the survival of patients was obtained by Cox regression model. The software used to analyze the data was STATA 11 and the significance level was 0.05.
Ethical Considerations: This study with research ethics code IR.UMSHA.REC.1396.144 was approved in Research Ethics Committee of Hamadan University of medical sciences, Iran.
Findings: The mean age of the patients at diagnosis was 57.09 ± 12.9 years. The probability of survival of one-, three- and five-year was 0.82, 0.61 and 0.48 percent, respectively. Also, the cancer stage has a significant effect on survival time of the patients.
Conclusion: Based on the Cox model, only the stage of cancer was effective on the survival time of patients with colon cancer. Therefore, timely diagnosis also helps prevent disease progression, as well as increase the survival time of the patient, especially at an advanced age.
Fatemeh Amiri, Mohammad Rafiei, Rasoul Najafi,
Volume 22, Issue 3 (8-2019)
Abstract
Background and Aim: Reducing the fertility rates in Iran and use of multiple contraceptive methods in recent decades have been affected by many social, economic and demographic factors. Therefore, this study was conducted to study the fertility pattern and common preventive fertility methods at Arak city in 2017 year.
Materials and Methods: This cross-sectional study was conducted on 384 married women referred to Arak remedial centers in 2017 year. The participants were randomly selected from Vali Asr, Taleghani and Amir Kabir hospitals. The participants information was collected using questionnaire and subsequently analyzed using Stata software version 12.
Ethical Considerations: This study with research ethics code IR.ARAKMU.REC.1396.4 has been approved by research ethics committee at Arak University of Medical Sciences.
Findings: Our results showed that the mean age and average duration of marriage of women were 40.03 ± 11.19 and 21.08 ± 12.73 respectively, as well, 281 (73.2%) of women used the natural fertility prevention methods. Most of the participated women were post-graduate diploma with lacked income and housekeeping. Other contraceptive methods such as pills, condoms, IUDs, one-month menses and three-month injections were 8.9, 3.28, 6.38, 1.7 and 2.6, respectively.
Conclusion: The most common method for preventing fertility is natural method. Condoms and pills are used more than the other contraceptive methods. There is a lack of awareness of modern contraceptive methods. Therefore, it is recommended that married women be educated about educational materials and counseling for familiarizing them with contraceptives. |
Fatemeh Amiri, Rasoul Najafi,
Volume 23, Issue 3 (August & September 2020)
Abstract
Background and Aim: Fertility pattern is one of the most important determinants of population fluctuations. Various individual and social factors affect this pattern. This study aimed to determine the factors affecting the fertility pattern using the structural equation model.
Methods & Materials: In this cross-sectional study, 384 women were randomly selected from married women of childbearing age who referred to Taleghani, Valiasr, and Amir Al-Momenin hospitals in Arak as patients. After obtaining verbal consent to participate in the study, a researcher-made and valid questionnaire was completed for them. Structural equation modeling was used to measure the effect of important individual and social variables on fertility patterns. Data analysis and analysis were performed with AMOUS software version 11 and SPSS V. 22.
Ethical Considerations: This study was registered with the ethics code IR.ARAKMU.REC.1396.4 by the Research Ethics Committee of Arak University of Medical Sciences.
Results: The Mean±SD age of the participants in the study was 40.03±11.19. The variables affecting the fertility pattern using the structural equation model included, respectively, the type of individual exercise, the method of contraception, the type of infertility treatment, and the duration of use of the contraceptive method.
Conclusion: The results showed that physical activity, contraceptive method, and duration of use of this method and the type of infertility treatment were related to fertility pattern. By recognizing the factors affecting the fertility pattern and increasing the awareness of young couples, it is possible to help improve the fertility pattern.
Said Ariapooran, Marzieh Amirimanesh,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: Nurses experience many psychological problems during the Coronavirus Disease 2019 (COVID-19) outbreak. This study aims to investigate the prevalence of depression, anxiety and suicidal ideation in nurses during the COVID-19 outbreak, and compare these problems in nurses based on gender, educational level, marital status and department.
Methods & Materials: This is a descriptive study conducted on 312 nurses working in hospitals in Malayer, Iran. who were selected using census method. They completed the Beck Depression Inventory, Beck Anxiety Inventory, and Scale for Suicidal Ideation questionnaire. Descriptive statistics and Multivariate Analysis of Covariance (MANCOVA) were used to analyze the collected data in SPSS v. 24 software.
Ethical Considerations: This study was approved by the Research Ethics Committee of Malayer University (Code: IR.MALAYERU.REC.1399.002).
Results: It was reported that 15.38% of nurses had moderate-to-severe depression; 46.47% had moderate-to-severe anxiety, 27.56% had plans for suicide, and 9.94% had active suicidal desire. The results of MANCOVA showed that depression (P=0.009) and anxiety (P=0.001) in female nurses was significantly higher than in male nurses. Depression and suicidal ideation of nurses with bachelor’s degree were higher compared to nurses with master’s degree (P=0.01). Anxiety and suicidal ideation of single nurses were higher compared to married nurses (P=0.01). Nurses in the emergency department (P=0.03), ICU/CCU (P=0.04) were more anxious than the pre-hospital emergency nurses.
Conclusion: Prevalence of depression, anxiety and suicidal ideation in nurses during the outbreak of COVID-19 in Iran is high. Therefore, it is recommended to use psychological therapies to reduce their depression, anxiety and suicidal ideation during the outbreak.
Mojgan Moaref Khanli, Mohammad Akbari, Ali Amiri,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: Conventional post-operative rehabilitation programs focus on quadriceps strengthening and knee range of motion. However, hip muscle weakness is evident in patients with knee osteoarthritis. The present trial study aimed to investigate the effects of adding early hip muscle strengthening exercises to conventional rehabilitation programs on pain, Range of Motion (RoM), Quality of Life (QoL), and physical function in patients with unilateral Total Knee Arthroplasty (TKA).
Methods & Materials: The intervention was initiated from the second day after surgery and continued for 10 sessions, 3 times a week on 24 participants in the control and intervention groups. Both research groups received Transcutaneous Electrical Neural Stimulation (TENS) and Infra-Red (IR), followed by exercises. The control group performed knee extensor and flexor strengthening and RoM exercises. The intervention group conducted hip-strengthening exercises in addition. Outcome measures included pain, knee flexion, and extension RoM, and QoL using the 36-Item Short Form Survey (SF-36), Timed Up and Go (TUG) test, Step Test, Six-Minute Walk Test (6MWT), and Hip and Knee Muscle Strength test.
Ethical Considerations: This research was approved by the Research Ethics Committee of Iran University of Medical Sciences (IR.IUMS.REC.1396.9511340012) and it was registered in the Clinical Trial Registration Center (Code: IRCT 20150314021459N6).
Results: All outcome measures improved in both research groups. The improvement in the scores of pain (P=0.03), knee extension RoM (P=0.007), and TUG test (P=0.033) were significantly higher in the intervention group, compared to the control group. The strength of knee flexors (P=0.023), hip flexors (P=0.040), hip extensors (P=0.028), hip adductors (P=0.040), and hip external rotators (P=0.047) significantly improved higher in the intervention group.
Conclusion: According to the present research results, both treatment approaches were effective on patients with unilateral total knee arthroplasty. Considering the better result of some of the outcome measures in the intervention group, the addition of hip strengthening exercises to knee exercises can be useful.
Fatemeh Amiri, Ghodrat Roshanaei, Meysam Olfati Far, Rasoul Najafi, Jalal Poorolajal,
Volume 24, Issue 2 (June & July 2021)
Abstract
Background and Aim: Acquired Immunodeficiency Syndrome (AIDS) caused by Human Immunodeficiency Virus (HIV), is a chronic and potentially life-threatening disease. Numerous factors affect its development and progression. Therefore, the present study attempted to identify characteristics impacting the prognosis and progression of AIDS using multistate models.
Methods & Materials: The present retrospective study consisted of 2185 patients affected with HIV referring to Behavioral Disease Counseling Centers in Tehran City, Iran, from 2004 to 2013. We considered multiple states of AIDS, tuberculosis, and tuberculosis/AIDS in the natural history of the disease (from the onset of HIV disease until death occurred). Then, we applied the multistate models, to examine the effect of contextual demographic and clinical variables on survival time; subsequently, the transition probabilities of HIV.
Ethical Considerations: This study was approved by the Research Ethics Committee of Hamadan University of Medical Sciences (Code: IR.UMSHA.REC.1396.117).
Results: HIV-Related deaths in individuals with an incarnation history were 2.40 times higher than in those without the prison history. Death risk was also 1.70 and 1.80 times higher in those aged 25-44 and 44 years, respectively, compared to the individuals aged less than 25 years. An inverse relationship was also found between CD4 levels and the risk of death in our participants.
Conclusion: Antiretroviral therapy, CD4 count, age, and history of imprisonment were the main factors in the progression of the disease and subsequent death in HIV patients. Thus, preventing the further spread of the disease to the community and controlling the disease in the patients requires targeted educational and therapeutic interventions; accordingly, the community will be familiarized with transmission routes and the preventing principle of disease. Furthermore, we can encourage patients to visit the healthcare centers early.
Seyedeh Sara Azadeh, Hoda Keshmiri Neghab,
Volume 24, Issue 5 (December & January 2021)
Abstract
In December 2019, a new type of coronavirus called COVID-19 was identified as an unknown cause of pneumonia in Wuhan, China. The pandemic virus was transmitted to humans from a type of seafood that could spread significantly among humans in a short time. Clinical signs of coronaviruses include fever, severe sweating, cough, pneumonia, and a weakened immune system, with acute cases leading to death. One of the most important coronavirus receptors in the host cell is the angiotensin 2 converting enzyme. It is noteworthy that the patient’s recovery process increases during the inhibition of angiotensin 2 converter enzyme. Therefore, the administration of drugs that inhibit this enzyme can be effective in recovering a patient with coronavirus. Flavonoids are one the inhibitors of the angiotensin-converting enzyme, which is abundant in fruits and vegetables. Fistula, a type of flavonoid known in nature as an antioxidant and anti-inflammatory agent in the treatment of many, can be effective in the treatment of coronavirus by inhibiting the enzyme converter angiotensin 2.
Mohammadrahim Amiri, Bayan Heydaryan, Fariba Moradivastghani, Sara Imani Brouj,
Volume 27, Issue 2 (5-2024)
Abstract
Introduction: The present study findings aimed to investigate the effect of exercises based on the American National Academy of Sports Medicine principles (NASM) on walking kinetics in piriformis syndrome in middle-aged men.
Methods: The current research was semi-experimental and laboratory-type. The statistical sample of the present study was 30 men with piriformis syndrome. Subjects were equally and randomly placed in two intervention and control groups. The intervention group performed NASM exercises for eight weeks. Before and after the exercises, the ground reaction force variables were measured using a Bartek force plate device with a sampling rate of 1000 Hz. Kinetic data were smoothed using a fourth-order Butterworth filter with a frequency cutoff of 20 Hz. For statistical analysis, analysis of variance and paired T-test were utilized at the significance level of P < 0.05.
Results: The findings of the present study showed that the effect of time on the FxHC and FyHC components at the peak of the forces and the FyHC component at the time of reaching the peak of the ground reaction force increased in the post-test compared to the pre-test. P > 0.025;
d = 0.64 - 0.96. The effect of the time factor in the FyPO component at the peak of the ground reaction force in the post-test was less than the pre-test (P < 0.025; d = 1.64-0.96). The interaction effect of the time × group in the FxPO component at the peak of the force and the FzHC component at the time of reaching the peak of the ground reaction force had a significant difference (P < 0.048; d = 0.87-0.83).
Conclusions: The NASM exercises used in this research can have a clinical and therapeutic effect that can reduce damage to the lower limbs and improve the quality of walking in people with piriformis syndrome.
Mostafa Mirzaei, Mohammadreza Amiri Nikpour, Rezvan Noruzzadeh,
Volume 28, Issue 2 (4-2025)
Abstract
Introduction: Imaging of the vascular system supplying the brain parenchyma is a diagnostic tool in the evaluation of stroke patients. This study aimed to compare the results of digital subtraction angiography with color Doppler ultrasound of the carotid arteries in patients with ischemic stroke.
Methods: In this cross-sectional-analytical study, the medical records of patients with ischemic stroke admitted to Imam Khomeini Hospital from July 1401 to July 1402 were reviewed to collect data. Demographic information, along with the results of color Doppler ultrasound and digital subtraction angiography of the patients, were extracted and evaluated.
Results: This study included 48 patients with ischemic stroke with a mean age of 12.8 ± 0.67 years. Hypertension was present in 68.8%, diabetes mellitus in 20.8%, and smoking in 25% of patients. Based on the results of digital subtraction angiography and color Doppler ultrasound, the most common vascular abnormality was plaque (79.2%). Vascular stenosis and occlusion were present in 91.7% of patients. Color Doppler ultrasound in examining the right and left internal carotid arteries had a sensitivity of 94.9% and 92.8%, specificity of 66.7% and 38.9%, positive predictive value of 92.1% and 70.3%, and negative predictive value of 75% and 77.8%.
Conclusions: Color Doppler vascular ultrasound demonstrated high sensitivity and specificity in detecting the presence and severity of stenosis in internal carotid arteries of ischemic stroke patients, supporting its use as a non-invasive and cost-effective method in clinical practice.
