Showing 60 results for Morad
Azadeh Safari, Mehdi Moradi, Mojtaba Khansooz,
Volume 23, Issue 2 (June & July 2020)
Abstract
Background and Aim: The purpose of this study was to investigate the effect of eight weeks of aerobic exercise and the consumption of kefir dough on anthropometric indices, plasma lipid profile and blood pressure in overweight non-athletic women.
Methods & Materials: This quasi-experimental study was performed on 32 non-athletic women with overweight in Arak, Iran (mean age= 33.94±8.58 years, mean height= 1.59±0.05 cm, mean weight= 70.15±6.88 kg, and body mass index= 27.35±1.50 kg/m2) who were voluntarily selected and randomly divided into four groups of 8 (control, exercise, exercise + supplement, and supplement). The control group had a normal diet without exercise; the supplement group received 100 ml kefir dough three meals a day for 8 weeks; the exercise group performed aerobic exercise for 8 weeks, 3 sessions per week, each for 50 minutes. The exercise + supplement group received both aerobic exercise and kefir dough. Blood and anthropometric variables were measured at the beginning and at the end of the intervention. Paired t-test was used to examine the within-group variations and one-way ANOVA to examine the between-group variations. All statistical tests were performed at the significant level of P<0.05.
Ethical Considerations: This study has obtained its ethical approval from the Research Ethics Committee of Qom University (Code: IR.QOM.REC.1398.01).
Results: The combination of kefir dough supplementation and aerobic exercise significantly reduced the mean blood pressure (P=0.003) and BMI (P=0.03) but had no significant effect on total cholesterol (P=0.27), triglycerides (P=0.61), high-density lipoprotein (P=0.16), low-density lipoprotein (P=0.30) and waist-to-hip ratio (P=0.24).
Conclusion: Overweight women can benefit from the aerobic exercise combined with kefir dough supplementation to reduce their blood pressure and BMI. Further studies are recommended to determine the effect of aerobic exercise and kefir supplementation on serum total cholesterol, triglyceride, low- and high-density lipoproteins, and waist-to-hip ratio.
Mohammad Parastesh, Jalil Moradi,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: Coronavirus Disease 2019 (COVID-19) pandemic has reduced the physical activity of people worldwide. The purpose of this study is to provide a practical guide for performing physical activities at home during the COVID-19 pandemic.
Methods & Materials: The study was conducted by using library method and reviewing the books and articles on home-based physical activity, to provide a scientific basis for performing physical activity at home. In this regard, various physical activities with and without equipment at homes were examined.
Ethical Considerations: This article is a review article with no human or animal sample.
Results: Home-based practical suggestions for staying active and cope with its physical and psychological consequences of the COVID-19 pandemic were reported walking or running on a treadmill, the use of stationary bikes, and body weight resistance exercise, in addition to aerobic exercise.
Conclusion: This proposed physical activity programs can be used during the pandemic at home by people with sedentary lifestyle.
Abolfazl Morad, Mehdi Zeinoddini,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: In the microbial contamination of food and water, identifying the trace amounts of contaminating bacteria has always been of researchers’ interest and concern. The most frequent approach to resolve this problem is using culture-based methods to increase and enrich bacteria samples; accordingly, it extends the bacterial detection process to several hours or days. One of the smart strategies to solve this problem is the concentration of bacteria using physical methods. The present study aimed to enrich Vibrio cholerae as the most essential water-polluting germs. Accordingly, we used the filtration method and evaluated its function by culture method and two detection approaches of Adenosine Triphosphate (ATP) and PCR assay.
Methods & Materials: A certain concentration of V. Cholerae was artificially added to a specified volume of sterile water. Then, the bacteria were extracted from the medium and filtered using 0.450 µm separable filters. Finally, the performance of the pre- and post-filtration processes was compared using bacterial cell culture (CFU), ATP, and PCR assay with the specific primers for the ompW gene of V. cholerae.
Ethical Considerations: This article is a meta-analysis with no human or animal sample.
Results: The present research results indicated that the applied method presented high efficiency and recovery performance. In other words, samples provided no positive response before filtration in both methods; however, after filtration in isolated and recovered samples, the presence of bacteria was detected in the ATP and PCR methods.
Conclusion: In conclusion, the employed strategy can detect V. cholerae in non-culture and in the shortest time in contaminated water samples.
Zahra Jahangiri, Mohsen Shamsi, Mahboobeh Khorsandi, Rahmatollah Moradzade,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: Iron deficiency is among the most prevalent nutritional problems during pregnancy. Besides, it can significantly affect pregnant women’s health. Therefore, this study aimed to determine the effect of education based on the Theory of Planned Behavior (TPB) on promoting anesthetic prevention nutritional behaviors in the pregnant woman.
Methods & Materials: This was an educational randomized controlled trial study. In total, 80 pregnant women were randomly divided into two groups of test and control (n=40/group). Data collection with reliable and validity questionnaire consist of demographic factors, knowledge, the construct of TPB (attitude, subjective norms, perceived behavior control, intention), and performance. Before performing the intervention, pre-test data were collected from the study groups. Then, the educational intervention was performed based on the results of the needs assessment for the test group, within a month and in the form of four 60-minute training sessions based on the TPB. The results were collected 3 months after the intervention and analyzed using the Mann-Whitney U test, Chi-squared test, and correlation coefficient.
Ethical Considerations: The present study was registered with the code IRCT2017052334106N1 in the Clinical Trial Registration Center of Iran and was approved by the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1395.445).
Results: The present research results indicated that before the intervention, all variables were the same in the study groups. However, after the intervention, the research groups significantly differed concerning all the studied structures (P<0.05). Moreover, the Mean±SD pre-test performance score of the intervention group was equal to 2.88±0.415 (out of 5); accordingly, it was significantly improved after training to 3.64±0.216 (P<0.001).
Conclusion: Educational intervention based on the TPB improved anesthetic anxiety behaviors in the studied pregnant women; such a modification can be attributed to the provided educational program in the intervention group.
Maryam Moradi, Mahla Salarfard, Zahra Abedian, Seyed Reza Mazloum, Ehsan Mousa Farkhani,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: The adherence of diabetic patients to the recommended treatment regimens is among the major challenges in diabetes control. Dietary adherence is low in pregnant women with gestational diabetes. Non-compliance can reduce the beneficial effects of treatment, symptoms, and signs, increase complications, or even cause death. Therefore, further research on the determinants of follow-up behaviors is essential.
Methods & Materials: This was a descriptive-analytical study. In total, 260 women with gestational diabetes treated with diet referring to healthcare centers, and Imam Reza (AS), Ghaem, and Umm Al-Banin Hospitals in Mashhad City, Iran participated in this research. The study subjects were selected using convenience, multistage, class, and cluster sampling methods. The required data were collected using a demographic and pregnancy profile questionnaire and a researcher-made questionnaire of adherence to the treatment regimen. The obtained data were analyzed by inferential statists and regression tests in SPSS v. 16.
Ethical Considerations: This study was registered with ethics code of IR.MUMS.NURSE.REC.1397.091 in the ethics committee of Mashhad University of Medical Sciences.
Results: The regression analysis results indicated that dietary adherence, blood glucose monitoring, and exercise adherence scores presented a significant and positive effect on the total treatment adherence score (P<0.001). Furthermore, education (P=0.044), unwanted (P=0.006), or unplanned pregnancy (P=0.21) provided a positive and significant effect on the overall score of treatment adherence. Women with a history of diabetes in first-degree relatives (P=0.010) and those with a history of miscarriage (P=0.021) obtained higher scores of total treatment adherence.
Conclusion: According to the present study findings, some demographic and pregnancy characteristics can affect the rate of adherence to the treatment regimen in women with gestational diabetes. Healthcare providers need to pay attention to the impact of these factors in improving adherence to patients’ treatment regimens.
Abbas Alimoradian, Saeed Pazhoohan, Omid Mirzabeygi, Kiana Naderinia,
Volume 23, Issue 6 (February & March 2020)
Abstract
Background and Aim: Opioid and benzodiazepine family drugs are concurrently used in various patients. Considering the respiratory depressant effects of both classes, in this study, we investigated the effect of coadministration of morphine and several widely used benzodiazepines in the clinic on the rate of respiratory depression in rats.
Methods & Materials: Seventy adult male Wistar rats were randomly divided into 10 groups; morphine, midazolam, diazepam, lorazepam, alprazolam, morphine-midazolam, morphine-diazepam, morphine-lorazepam, and morphine-alprazolam. Respiration signal was recorded using whole-body plethysmography 15 minutes after the intraperitoneal injection of the drugs. The respiratory pattern was examined using several parameters; the mean value of inter-breath interval and the respiratory rate, as well as the coefficient of variation and sample entropy analysis of inter-breath interval.
Ethical Considerations: This study was approved by the Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.327).
Results: Analyzing respiratory data revealed that injecting the anxiolytic dose of alprazolam, and the combination of morphine-alprazolam and morphine-midazolam, altered the respiratory pattern. Such changes were associated with a decrease in the number of breaths and an increase in the inter-breath interval in the explored test animals, compared with the controls. The obtained data also indicated that morphine-midazolam injection increased the variability of the breathing pattern; such an alternation was associated with increased irregularity and decreased coefficient of variation of the inter-breath interval.
Conclusion: The present research results suggested that the short-term injection of morphine-midazolam changes the respiratory pattern more severely than morphine combined with other benzodiazepines.
Soheila Zolfaghari, Omid Moradi, Hamzeh Ahmadian, Narges Shams Alizadeh,
Volume 24, Issue 2 (June & July 2021)
Abstract
Background and Aim: The quality of sexual satisfaction of couples plays an essential role in marital dissatisfaction; therefore, sexual satisfaction training can be effective in reducing this marital problem. The present study aimed to investigate the effects of sexual satisfaction model training on reducing couples’ distress among couples referring to counseling centers.
Methods & Materials: This was a quasi-experimental study with pretest-posttest and a control group design. The statistical population of the study included all couples referring to counseling centers in Sanandaj City, in the academic year of 2019-2020. The instruments used in this research were Couple Burnout Measure (CBM). After selecting the sample and randomly forming two groups of 30 experimental and control groups, a pretest was conducted on the study groups. The researcher provided eight 90-minutes training sessions to the experimental group as a model of sexual satisfaction. The obtained data were analyzed using SPSS.
Ethical Considerations: This study was approved by Ethics Committee of Kurdistan University of Medical Sciences (Code: IR.MUK.REC.1397.5037).
Results: The current research results revealed a significant difference (P≤0.001) between the experimental and control groups concerning marital boredom (F=35.581) and its dimensions, including physical fatigue (F=25.074), emotional exhaustion (F=39.031), and mental exhaustion (F=35.020); the effect of the educational program was equal to 0.42, 0.31, 0.41, and 0.39, respectively.
Conclusion: The present study findings indicated that sex education model training was effective in reducing couples’ referrals to counseling centers.
Faranak Moradi, Ali Akbarnejad,
Volume 24, Issue 3 (August & September 2021)
Abstract
Background and Aim: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder in women of reproductive age. In cross-sectional and longitudinal studies, exercise training is an effective solution for treating and declining the symptoms. This study aims to compare the effects of the voluntary and the endurance exercise on some of the inflammatory and hormonal markers in rats with PCOS.
Methods & Materials: In this study, Which was experimental and applied in terms of purpose, 40 female Wistar rats with Mean±SD weight of 220±20 g were divided randomly into four groups of ten: 1) control, 2) PCOS, 3) PCOS + Running wheel and 4) PCOS + endurance training. The rats in the voluntary group experienced voluntary activity of wheel running for 8 weeks (5 times a week). Alternatively, the endurance training group underwent aerobic exercises for 8 weeks (5 sessions in a week) on a treadmill. The blood samples were taken from the heart to measure the concentration of interleukin-6 and testosterone level and were analyzed by one-way analysis of variance and LSD post hoc test.
Ethical Considerations: This study was approved by the Tehran University, Iran (Code: IR.UT.REC.1395016).
Results: The results showed no significant difference in IL-6 and testosterone indices between endurance and voluntary training groups (P=0.565), (P=0.496). Both training groups (endurance and voluntary) separately resulted in a significant reduction in il6 and testosterone compared to rats with PCOS (P=0.002), (P=0.000), (P=0.038), (P=0.007).
Conclusion: Altogether, the present study’s findings suggest that voluntary and endurance training in rats have similar effects on IL-6, Testosterone, and weight.
Marjan Hajimoradi Javarsiani, Javad Sajedianfard, Shagayegh Haghjooy Javanmard,
Volume 24, Issue 3 (August & September 2021)
Abstract
Background and Aim: Cancer cannot be explained only by genetic alterations but involves epigenetic processes. Modifying histones by acetylation plays a key role in epigenetic regulation of gene expression and is controlled by the balance between Histone Deacetylases (HDAC) and Histone Acetyltransferases (HAT). The HDACs expression and activity could be involved in several tumorigenesis mechanisms, so their inhibition induces cancer cell cycle arrest and migration.
Methods & Materials: Quisinostat is a novel promising second-generation HDAC inhibitor class of hydroxamic acid with high cellular potency towards classes I and II HDACs. Therefore, its low IC50 (<0.5nM) and bioavailability have been chosen to carry out our studies. Cancer cells were treated with Quiznos at nM200, and cell migration was measured by fluorescent microscopy.
Ethical Considerations: This study was the result of a preliminary study of Shiraz University (Code: 96GCU3M1293).
Results: The data showed that treatment of cancer cells with Quiznos significantly (P<0.05) reduced cell migration. DMSO did not affect reducing cell migration.
Conclusion: In this project try to explore the possible therapeutic application of this HDAC inhibitor against colon cancer. This study showed Quisinostat exerts broad-spectrum antiproliferative activity and migration.
Saeed Pirmoradi, Hedieh Jafari,
Volume 24, Issue 4 (October & November 2021)
Abstract
Background and Aim: The human coronavirus is a member of the Coronaviridae family and causes upper respiratory tract infections. Despite repeated severe epidemics and the lack of appropriate antiviral drugs, not much progress has been made on the epitope-based vaccine designed for HCoV.
Methods & Materials: The method of this study was to select the spike corona virus protein sequence from NCBI, retrieve the protein sequence and determine the T, B epitopes required to produce the chimer vaccine, evaluate the antigenicity and allergenicity and toxicity of the selected epitopes, respectively. Different servers were designed to configure the primary chimer composition of the epitope vaccine. Then, the chimer vaccine was evaluated in terms of structure and connectivity to B cells and MHCI and II compounds, and the two-dimensional structure and position of amino acids and bonds in the immunogenic model were studied, as well as the physicochemical and stability of the model vaccine by some other servers. Finally, it was tested for binding against HLA molecules using silico docking techniques to investigate the interaction with the epitope.
Ethical Considerations: All ethical principles are considered in this article. Participants were informed about the research objective and its implementation stages. They also made sure their information was confidential. The principles of the Helsinki Convention were also observed.
Results: The results showed that the immunogenic construct created in terms of two-dimensional and three-dimensional structure and the position of amino acids and bonds in the model of immunogenic structure, toxicity and allergenicity and antigenicity were in good condition. And had stability (instability index 33.93) and favorable half-life and suitable physicochemical conditions.
Conclusion: In general, the immunogenic structure that was prepared in this research process could have a favorable interaction with some components of the immune system (HLA) in the docking process, which indicates the optimal identification of this structure by the humoral and cellular immune system and stimulation in In order to produce immunity in the body of the host, of course, more reliable proof of it requires clinical phase processes.
Rahmatollah Moradzadeh, Iman Navidi, Maryam Zamanian,
Volume 24, Issue 5 (December & January 2021)
Abstract
Background and Aim: AIDS (Acquired Immune Deficiency Syndrome) is a deadly disease that affects the human immune system. This study evaluated the Quality of Life (QoL) of Human Immunodeficiency Virus (HIV) patients in Markazi Province .
Methods & Materials: This cross-sectional study was conducted in 2020-2021 in Markazi Province . The World Health Organization (WHO) questionnaire was used to determine the QoL in HIV patients. This questionnaire includes the physical, psychological, level of independence, social relationship, environment, and spirit. Statistical analysis was performed in STATA software.
Ethical Considerations: This study was approved by the ethics committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1398.008).
Results: A total of 126 people with HIV were included in the study. The mean age of the subjects was 40.4±10.2 years. The mean score of each of the physical domains was 14.4±3.3, psychological 11.7±3.2, independence 13.3±3.8, social relationships 11.2±3.1, environment 0.8±0.3 10, spiritual was 13.2±3.3, and total QoL score was 12.1±2.6. In multivariate linear regression analysis, socioeconomic status and history of imprisonment significantly predicted higher scores of overall qualities of life.
Conclusion: The total score of QoL in people with HIV in Markazi Province is average. Among the factors affecting it are gender, socioeconomic status, and history of imprisonment. It is suggested that QoL assessment of these patients be added to their care protocols to take effective measures to improve it.
Kolsoum Mohammadniamotlaghh, Mohsen Shamsi, Nasrin Roozbahani, Mahmood Karimy, Rahmatalah Moradzadeh,
Volume 24, Issue 5 (December & January 2021)
Abstract
Background and Aim: A lack of healthy nutrition first causes prediabetes and then overt diabetes, and every year about 5% to 10% of people with glucose intolerance develop type 2 diabetes. This study aimed to assess the factors affecting the consumption of healthy foods (CHF) based on the food pyramid among prediabetic women based on the Theory of Planned Behavior (TPB).
Methods & Materials: This cross-sectional study was conducted in 2019 on 99 prediabetic women selected from comprehensive healthcare centers in Arak, Iran. A demographic questionnaire, a TPB-based questionnaire, and a food consumption Questionnaire were used for data collection. Data were analyzed through Spearman’s correlation and linear regression analyses.
Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1398.07).
Results: The Mean±SD score of diet behavior was 1.34±0.28 (in the possible range of 0-2). Around 41% of participants consumed sugary foods such as sweets and chocolate at least once a week and 35% at least once a month. Regression analysis shows that by increasing a standard deviation in the behavioral intention score, the behavior score of a healthy diet will increase by 0.22 standard deviation (P<0.05).
Conclusion: To achieve a healthy lifestyle in the individual at risk for a diabetics education program to increase perceived behavior and motivation for decision making for adherence to healthy food can be attention for policymakers in a health system.
Anis Moradi, Pouya Ramin,
Volume 24, Issue 5 (December & January 2021)
Abstract
Background and Aim: The research results show tobacco use increases cardiovascular and lung disorders or the probability of periodontitis in humans, while no definitive relations were yet confirmed. This study evaluates the relationship between periodontitis and tobacco use by panoramic radiography in Bandar Abbas City.
Methods & Materials: A total of 198 panoramic radiographs were classified into periapical healthy (n=99) and patient (n=99) groups. Radiologists assessed radiographs for periodontitis via Total Teeth Numbers (TTN), the quality and length of Root Filling Treatment (RFT), the number (NoRFT), and inadequate root filling treatment (RFTin), age, gender, the cigarette and hookah use, and dental debris. Data were analyzed by Chi-Square, t-test, and logistic regression.
Ethical Considerations: Due to the lack of therapeutic intervention and the preservation of patients’ characteristics, ethical considerations are not included in this study (Code: IR.HUMS.REC.1399.384)
Results: Tobacco, hookah use, TTN, and RFTin were different (P<0.01) in groups, but cigarette smoking, debris, RFT, NoRFT, and age were not. Women in the periodontitis group showed high (P<0.01) in tobacco, hookah use, and RFTin, while no gender differences were observed in other parameters. The logistic regression results showed that based on the Odd Ratio NoRFT (39.7), RFTin (36.8), `hookah (8.1), tobacco (6.57), debris (3.62), smoking (3.59), RFT (1.4) and TTN (0.89) were the highest (P<0.01). At the same time, age and gender did not affect periapical tissues.
Conclusion: Hokka, tobacco, and cigarette use negatively affected the periapical tissues, respectively. The decrease in TTN and increase in debris and RFT were probably the effects of tobacco smoking on the periapical tissues. Age and gender were not related to the periapical lesions.
Doctor Monireh Nadeali, Doctor Mojtaba Bayani, Doctor Vahideh Nazari, Doctor Rahmatollah Moradzadeh,
Volume 24, Issue 6 (February & March 2022)
Abstract
Background and Aim: Different implant angulation, which is unavoidable in clinical situations, can affect the accuracy of impression. The aim of this study was to investigate the effect of fixture position on the accuracy of connecting impression coping to implants with internal hex.
Materials and Methods: A gypsum model with 4 implants with internal hex connection was prepared. The implants were installed in different mesiodistal angles of 0, 15, 25 and 35 degrees to the longitudinal axis in the gypsum model. To simulate the gums, a gingival mask was injected around the implants to a height of 2 mm. After a training session for senior dental students on how to close the impression coping, forty students were asked to close the impression copings on four implants. The correctness of the impression coping was evaluated by an expert prosthodontist. Data were statistically analyzed using Cochran Q test. Significance level was considered 0.05.
Ethical Considerations: this article is approved by ethics committee of Arak University of Medical Sciences.
Findings: The correct performance of students in connecting the impression coping to the implant at angles of 0, 15, 25 and 35 degrees was equal to 85%, 72%, 52%, 35%, respectively. With the exception of 0 and 15 degree groups, a statistically significant difference was observed between different study groups.
Conclusion: The fixture position has a significant effect on the accuracy of connecting impression coping to the implants with the internal hex and by increasing the implant angulation, the accurate connection the impression coping to the implant decreases.
Abbas Saremi, Dr Rahmatollah Moradzadeh, Alireza Bahrami,
Volume 24, Issue 6 (February & March 2022)
Abstract
Background and Aim Physical activity has multiple health benefits, but its association with fertility in women is still unknown. Considering the critical effects of lifestyle on reproductive health, this study aims to compare the physical activity and body composition of fertile and infertile women.
Methods & Materials This is a case-control study that was performed on 100 fertile and 100 infertile women aged 20-40 years referred to the infertility treatment centers in Arak, Iran. they completed self-reported questionnaires surveying sociodemographic characteristics and lifestyle, and the International Physical Activity Questionnaire (IPAQ) assessing physical activity and sedentary behavior. Anthropometric characteristics and body composition were also measured. Multiple logistic regression analysis was used to analyze the association of fertility with physical activity level, sedentary behavior, and body composition.
Ethical Considerations This study was approved by the Ethics Committee of the University of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1400.050).
Results The level of physical activity (P=0.001) was lower and the body mass index (P=0.03) was higher in infertile women than in fertile women. In women with moderate level of physical activity, the risk of infertility was lower (OR=4.42, 95% CI: 1.60-12.99, P=0.004). Women who spent the time sitting for more than 300 minutes a day were 2.07 times more likely to have fertility than women who were physically active (OR=2.07, 95% CI: 1.36-3.14, P=0.001).
Conclusion Low physical activity, sedentary lifestyle and obesity are independent risk factors of infertility. To prevent infertility, more attention should be paid to the lifestyle of women.
Mohammad Reza Heidari, Mehrdad Goudarzvand Chegini, Hamid Reza Rezaei Kelidbari, Morad Rezaei Dizgah,
Volume 25, Issue 2 (June & July 2022)
Abstract
Background and Aim The internationalization of higher education is an effective strategy to meet the diverse needs of a society. One of the factors determining the failure or success of internationalization is the organizational culture of universities. The present study aims to investigate the role of organizational culture-related factors in the internationalization of Iranian universities.
Methods & Materials This is a quantitative-quantitative study. Participants were 124 Iranian experts in higher education and those involved in internationalization of universities. A researcher-made questionnaire was used as a self-report tool with close-ended questions. In the quantitative stage, structural equation modeling and first- and second-order factor analysis were performed in SPSS and AMOS software.
Ethical Considerations This study was approved by the ethics committee of Islamic Azad University, Rasht Branch (Code: IR.IAU.RASHT.REC.1400.035)
Results The ranking of factors affecting the internationalization of Iranian universities showed that the factor with the highest factor loading was “communication & interaction” (1.03) and the factor with the lowest factor loading was “human/physical/financial resources” (0.87).
Conclusion Communication/interaction of universities with other education centers, as an organizational culture-related factor, plays an important role in the internationalization of Iranian universities.
Azin Niazi, Maryam Moradi, Ehsan Mazloumi,
Volume 25, Issue 3 (August & September 2022)
Abstract
Background and Aim Preeclampsia is a common complication of the second half of pregnancy. Sleep disorders can cause high blood pressure by causing oxidative stress and endothelial dysfunction. Therefore, the present study was performed to determine the relationship between sleep disorders and preeclampsia.
Methods & Materials This is a case-control study that was performed on 240 women referred to the affiliated university hospitals in Mashhad. Sampling was performed in the case group of hospitalized women with a definite diagnosis of preeclampsia (n=90) and in the control group (n=150) among pregnant women without preeclampsia referred to the obstetrics clinic. Data collection tools included demographic information questionnaire and gynecological/obstetric records, Pittsburgh Sleep Quality Questionnaire and clinical evaluation form to determine the symptoms and severity of preeclampsia. Data analysis was performed using SPSS statistical software (version 22) and Mann-Whitney, Chi-square and Fisher tests. A P value of less than 0.05 was considered significant.
Ethical Considerations The present paper is the result of a research project approved by the Vice-Chancellor for Research of Mashhad University of Medical Sciences (Code: IR.MUMS.NURSE.REC.1397.042).
Results The mean amount of real sleep at night in the group of healthy individuals (8.4±2.3) was significantly higher than patients (8.0±2.2) (P=0.028). In terms of loud snoring, waking up in the middle of the night was most frequent in the affected group (P<0.001). There was a statistically significant difference between the two groups in terms of sleep quality score level (P<0.001) based on logistic regression test in women with severe sleep problems at risk of preeclampsia (P<0.001, 95% CI 2.9-42.2, OR: 11/11) (11/11) was equal compared to healthy women.
Conclusion The present study showed that sleep disorders in pregnancy are associated with an increased risk of preeclampsia.
Ali Moradpoor Shamami, Dr Masumeh Anvari, Seyedeh Tooba Shafighi, Hadi Sedigh Ebrahim-Saraie,
Volume 25, Issue 5 (December & January 2022)
Abstract
Introduction: Considering the importance of urinary tract infections caused by uropathogenic Escherichia coli (UPEC) in the medical field, this study aimed to investigate serogroups O25 and O16 and the pattern of antibiotic resistance among UPEC isolates obtained from hospitalized patients with urinary tract infections (UTIs) in Rasht hospitals.
Methods: A total of 110 urine samples were collected from patients with UTIs referred to selected hospitals in Rasht. The disk diffusion method, as recommended by the CLSI, was used to determine the pattern of antibiotic susceptibility. Serogroups O25 and O16 were detected using specific primers.
Results: Among the studied samples, 36.4% (40/110) were men and 63.6% (70/110) were women. Based on the antibiotic susceptibility pattern, a high level of antibiotic resistance was observed against nalidixic acid (81.8%) and co-trimoxazole (78.2%), while the most effective antibiotics were amikacin (85.5%) and nitrofurantoin (83.6%). In addition, multi-drug resistant phenotype was found in 72.7% (110/80) of UPEC isolates. According to PCR results, the frequency of serogroups O25 and O16 was 36.4% and 17.3%, respectively. Both serogroups had the highest resistance to nalidixic acid and co-trimoxazole, while the lowest resistance in serogroup O25 to nitrofurantoin (20%) and amikacin (14.3%) and in serogroup O16 to imipenem (5.3%) and nitrofurantoin (10.5%).
Conclusions: This study showed that the high prevalence of MDR strains among UPEC strains is very worrying and professionals should be very careful in prescribing antibiotics for patients. Like most studies, the frequency of serogroup O25 was high, and probably, this serogroup can play a role in causing urinary tract infections and antibiotic resistance of UPEC strains.
Dr Sina Banijamali, Dr Oldooz Aloosh, Dr Vahan Moradians, Dr Tayeb Ramim, Dr Haleh Afshar,
Volume 26, Issue 3 (August & September 2023)
Abstract
Introduction: Patients with COVID-19 can have various and complex coagulation disorders that cause hypercoagulable conditions. Investigating the role of anticoagulants with different doses in the outcome of patients with COVID-19 seems to be needed. Therefore, the present study was conducted with the aim of predicting factors of severe disease, including the number of lymphocytes, LDH, and the recovery status of patients.
Methods: A cross-sectional study was conducted in patients with COVID-19 hospitalized in Hazrat Rasool Akram (PBUH) Hospital. Study entry includes acute respiratory symptoms caused by COVID-19 disease (uncontrollable cough, dyspnea, prolonged medicine and blood saturation drop) along with lung involvement in chest spiral CT scan without injection, SARS RT-PCR–CO virus test was positive and transfer to intensive care unit (ICU) was indicated. Anticoagulant starting time, type and dose of anticoagulant received and duration of use were recorded. Two groups of prophylaxis dose, higher dose than prophylaxis (medium dose and therapeutic dose) were divided.
Results: Out of the total number of patients referred to Rasul Akram Hospital, 90 people (43 women (47.8%) and 47 men (52.22%)) participated in this study. The average hospitalization in the ICU was 13.50 ± 12.39 days and 17.18 ± 13.36 days in the hospital. Also, the duration of coagulant therapy was 17.13 ± 13.38 days. 53 patients (58.9%) received a prophylactic dose, 28 patients (31.1%) received a therapeutic dose, and 9 patients (10%) received a moderate dose of anticoagulant. Anticoagulant in 74 patients (82.2%) was unfractionated heparin (UFH) and in 16 cases (17.8%) low molecular weight heparin (LMWH). The changes of LDH, number of lymphocytes, dimer, fibrinogen, ferritin and FDP according to the dose of anticoagulant assessed in the three groups of prophylaxis, treatment and no statistically significant difference. The mean of ICU admission days according to different doses of anticoagulant did not show a statistically significant difference.
Conclusions: Finally, the findings obtained from the study showed that the use of different doses of anticoagulant does not cause a difference in the level of LDH, number of lymphocytes, ferritin and FDP at different measurement times. Also, the length of stay in the hospital and the time of hospitalization in the intensive care unit did not differ between the groups receiving prophylactic anticoagulant, medium dose and therapeutic dose.
Mohammadrahim Amiri, Bayan Heydaryan, Fariba Moradivastghani, Sara Imani Brouj,
Volume 27, Issue 2 (5-2024)
Abstract
Introduction: The present study findings aimed to investigate the effect of exercises based on the American National Academy of Sports Medicine principles (NASM) on walking kinetics in piriformis syndrome in middle-aged men.
Methods: The current research was semi-experimental and laboratory-type. The statistical sample of the present study was 30 men with piriformis syndrome. Subjects were equally and randomly placed in two intervention and control groups. The intervention group performed NASM exercises for eight weeks. Before and after the exercises, the ground reaction force variables were measured using a Bartek force plate device with a sampling rate of 1000 Hz. Kinetic data were smoothed using a fourth-order Butterworth filter with a frequency cutoff of 20 Hz. For statistical analysis, analysis of variance and paired T-test were utilized at the significance level of P < 0.05.
Results: The findings of the present study showed that the effect of time on the FxHC and FyHC components at the peak of the forces and the FyHC component at the time of reaching the peak of the ground reaction force increased in the post-test compared to the pre-test. P > 0.025;
d = 0.64 - 0.96. The effect of the time factor in the FyPO component at the peak of the ground reaction force in the post-test was less than the pre-test (P < 0.025; d = 1.64-0.96). The interaction effect of the time × group in the FxPO component at the peak of the force and the FzHC component at the time of reaching the peak of the ground reaction force had a significant difference (P < 0.048; d = 0.87-0.83).
Conclusions: The NASM exercises used in this research can have a clinical and therapeutic effect that can reduce damage to the lower limbs and improve the quality of walking in people with piriformis syndrome.
