Showing 60 results for sadegh
Abdolrahim Sadeghi , Hosein Mozdarani ,
Volume 2, Issue 7 (Summer 1999)
Abstract
This research is performed to assess clastogenic capacity of cimetidine(CT) against clastogenic effect induced by benzene in terms of micronuclei. For this purpose micronuclei assay method was used. In each experimental group m 5 Balb /C mices was used. 24 hours after i. p .injections slides was prepared from bone marrow and frequency of micronuclei in polychromatic erythrocytes (PCEs) and normochromatic erythrocytes (NCEs) was obtained. Results indicated that CT at therapeutic dose (20mg/kg. b. w) can be reduce genetical damages (micronuclei) due to benzene (1010mg/Kb. B. w) with a dose- related manner (p<0.01, = -0.82). Therefore , our results indicated that CT has anticlastogenic capacity. According to above results and relatively long term use of CT, we suggest using it in the cases in which someone exposed to clastogenic agents such as benzene, especially when someone also suffer from diseases such as peptic ulcer.
Vahid Goharian, Mohammad Sadegh Rajaei, Saeid Sadrnia,
Volume 2, Issue 7 (Summer 1999)
Abstract
The aim of this study is to determining the prevalence of cigarette smoking and the causes of initiation in boy students of medical science in Arak university. Declining of smoking depends to recognizing risk factors specially in young age group and the results of this study use to evaluate the plans. This descriptive study was done with convenience sampling and studied all boy medical students in Arak university with self-administered questionaires in 77-78 curiculum. This survey instrument contained age, course of study, passed semesters, smoking bahaviour family history, praying and living site .The smoker also answered to question about time of initiation, mean of cost family information and the number who giving up the habit of smikong. 98.7% (n=475) of students with mean of age 23.06 years answered to question 34.3% had smoking bahaviour. The prevalence of smoking was the lowest among those who were married and negative family history. The prevalence of smoking in students who prayed was 1.4 of others. The most common cause of initiation were being resident with friends, stress life and initiation. Lowering we must improve the "NAMAZ" task and marriage accompaniment with lowering stress life and teaching for friend selecting and determining a suitable pattern for students in Arak university.
Abdolrahim Sadeghi, Hamidreza Rozati, Minou Golestani, Azadeh Moshtagh, Mozhgan Sadeghi , Zoreh Sari,
Volume 4, Issue 2 (Summer 2001)
Abstract
About 3-5 percent of population suffer from mental retardation (MR) mildly to severely. One of the most common causes of Mr is chromosomal aberrations. In this research, Chromosmal study was performed for 100 Mental Retarders (MRS) by G-banding Method. 100 MRS were suffering from downs syndromes: 21 cases with 21 free Trisomy, 1 case chromosomal mosaism and residual case had Robertsonian traslocation 14; 21 also chromosomal mosaism. Other 8 MRS had be structural aberrations in chromosmals such as inversion (3 cases), partial trisomy (1 case), ring 22 chromosme (1 case) and breakages in different chromosmes (3 cases). The results showed that chromosomal aberrations are frequent between Mental Retarderes and the most common chromosomal aberrations occure between MRS is 21 free trisomy.
Masoumeh Sadeghi, Norodin Moayedi, Hamid Reza Rooh Afza , Abdolmehdi Baghaie, Sedigheh Asgari, Pejhman Aghdak , Firozeh Sajadi ,
Volume 7, Issue 3 (Autumn 2004)
Abstract
Introduction: Diabetes is one of the most important problems in all countries. This study is designed to determine the prevalence of diabetes or glucose intolerance in central areas of Iran.
Materials and Methods: In a descriptive study in Arak, Isfahan and Najafabad cities, 12514 samples over 19 years old were selected by a multistage random sampling method. FBs and GTT were done. Lipid tests were also done in fasting. weight, height and blood pressure of samples were measured by standard methods. FBs>-126 or 2 hoursglucose >-200 was considered diabetes. Fasting glucose disturbance was considered with FBS <126 and glucose intolerance with 2 hours glucose >-140-200. Data was analyzed by SPSS software, t test, chi square and Fisher test.
Results: Of 12514 samples under investigation 51.1% were female. The overall diabetes incidence in urban and rural areas was 6.7% and 5.3% and in male and female 5.4% and 7.1% respectively .Mean of blood glucose was increased by age in both sexes. This was also increased in women of urban areas against women in rural parts. It was also found that glucose intolerance, known diabetes and newly diagnosed diabetes was increased by age. More than half of diabetes cases in all age groups were newly diagnosed. Blood pressure, age, BMI and abdominal obesity were higher in diabetics and those with glucose intolerance. These problems were more incident in women.
Conclusion: Regarding to the fact that diabetes is one of the major risk factors for noncommunitable disease and also its relative high incidence in central areas of Iran, it is necessary to have expanded programs for prevention and treatment diabetes family history.
Ali Nasimi, Sadegh Yousefi,
Volume 8, Issue 1 (Spring 2005)
Abstract
Dr Effat Sadeghin, Dr Ali Heidarian-Poor, Dr Farhang Abed,
Volume 9, Issue 2 (6-2006)
Abstract
Introduction: Infertility is an emotional crisis with physical, economic and psychosocial challenges, because it interferes with all personal life aspects. This event is a sever tension of life and produces strong emotional shock in the infertile couple. This study is done with the aim of comparison the psychiatric problems of infertile men and women referring to infertility clinic of Hamadan Fatemyeh Hospital. Materials and Methods: This is a cross-sectional analytical study. Sample size was 400 infertile men and women which were selected by convenience sampling. Data was collected by a demographic questionnaire and SCL90, and analyzed through descriptive statistics and independent T test. Results: Our study indicates that infertile women experience mental problem significantly more than men. With p<0.05 infertile women in 9 categorize of SCL90 including depression, anxiety, phobia, psychosomatic, interpersonal sensitivity, hostility, paranoid ideation and psychotics are significantly different from infertile men. Conclusion: It seems women experience more stress in personal, social and sexual life and women are more sensitive to infertility phenomena that probably is due to cultural problems, mental susceptibility and/or special forms of social communication
Hamidreza Roohafza, Bahamn Roohafza, Masoumeh Sadeghi,
Volume 10, Issue 2 (6-2007)
Abstract
Introduction: Stress is a condition that causes tension, disturbance in body and mind, discomfort and dissatisfaction. There are differences between stresses in the form of great life events and small daily stressful events. Regarding extension and variation of stresses in different parts of country, this study aims to investigate the prevalence and severity of stresses in central areas of Iran. Materials and Methods: This is a cross-sectional analythical study carried out on 6000 people older than 19 years old, selected from urban and rural areas of Isfahan, Arak and Najaf Abad on 2002, as a part of evaluation of the Healthy Heart program. Sampling method was cluster random sampling. Data was collected using GHQ-12 and stressors' type and severity questionnaire. Statistical analysis was performed using Chi square. Results: Of the total subjects under study %50.6 were male, and %49.4 female, with a mean age of 40.47±15.68 and 40.25±15.15 years respectivly. The proportion of women with high GHQ score was higher than men, which was more pronounced in Arak than the two other cities. There were also higher stress levels in unmarried and urban people. (p0.05)The most prevalent stressor included economical, social and job-related issues and the most severe were death, family related and economical events. Conclusion: This study on stress as an indicator of lifestyle reveals high stress levels in the population, which warrants appropriate planning and community-based interventions, to improve lifestyle and reduce stress.
- Masoumeh Delaram, Zahra Sadeghiyan,
Volume 13, Issue 3 (9-2010)
Abstract
Background: Dysmenorrhea is seen in nearly 5% of women with regular menstruation. In this regard, different methods have been proposed for treatment of dysmenorrhea, and drugs with fewer side effects are preferred. Hence, this study was done to detect the effect of echinophora- platyloba on primary dysmenorrhea. Materials and Methods: In a single-blind clinical trial, 60 students with primary dysmenorrhea were evaluated at Shahr-e-Kord University of Medical Sciences. The students were randomly divided into two groups of 30 each: Echinophora-platyloba extract and placebo. Data collection was done through visual analogue scale for detecting the intensity of pain. At the end of first and second months after treatment, the intensity of pain was determined in the two groups and compared with that before the intervention. Eventually, the data were analyzed through Chi square, t-test and Mann-Whitney test. Results: The means of dysmenorrhea severity scores two months before administering the drug in echinophora-platyloba and placebo groups were 8.46±2.75 and 8.80±2.53, respectively. Here the difference was not significant however, after administering the drug, the mean scores in intervention and non-intervention groups were 3.41±1.12 and 7.82±2.60, respectively, which indicated a significant difference between the two groups (p<0.001) . Conclusion: Both echinophora-platyloba extract and the placebo could reduce the severity of dysmenorrhea during the treatment, yet the effect of echinophora-platyloba was much greater than the placebo. Thus, the use of echinophora-platyloba extract is suggested in treatment of dysmenorrhea.
Sara Sadegh Moghaddam Abaspour , Naser Mahdavi Shahri, Seyed Mohammad Ali Shariat Zadeh,
Volume 15, Issue 3 (August 2012)
Abstract
Background: Obtaining cells from the patient, expanding cell population on a scaffold, and, eventually, grafting the tissue to the patient is one of the tissue engineering techniques to create replacement tissue structures. Blastema tissue is one of the cellular sources in this regard. This study investigated the use of human gum tissue to prepare a scaffold and the interaction between the three-dimensional tissue scaffold and blastema tissue. Materials and Methods: In this experimental study, human gingiva was prepared and through snap freezing method and the use of sodium dodecyl sulfate (SDS) and Triton X-100, went through cell bleaching. Then the provided scaffoldings were placed in 2-day-old blastema rings and stored in culture media for 25 days. Sampling of the blastema and scaffolding tissues was done once every five days. Results: The results confirmed the removal of the cells from the prepared scaffolds. Also, histological studies in the fifth and tenth days indicated cell penetration into the blastema scaffolds. In the fifteenth day, in addition to penetration, blastema cells division and differentiation as well as epidermis genesis were observed. In the twentieth and twenty-fifth days, infiltration, cell division, and differentiation processes continued. Conclusion: The findings of this study indicated the possibility of creating a natural scaffold of human gingiva through this method. This scaffold can have an inductive effect on cell behaviors such as such as migration, adhesion, division, and probable differentiation. However, further studies for demonstrating the identity of the cells and other properties of such a scaffold as well as the possibility of using it in gingiva tissue engineering are recommended.
Bahare Rahimi, Mana Shojapour, Abdorrahim Sadeghi, Ahmad Ali Pourbabayi,
Volume 15, Issue 3 (August 2012)
Abstract
Background: Pseudomonas aeruginosa is a human opportunistic pathogen which is considered one of the agents causing nosocamial infection. Recent studies have reported increased resistance of Pseudomonas aeruginosa to imipenem. The aim of this study was to determine resistance to antipseudomonal antibiotics including imipenem in Pseudomonas aeruginosa strains. Materials and Methods: In this cross-sectional study, 100 Pseudomonas aeruginosa strains obtained from clinical samples of patients in hospitals in Arak, Iran, were identified and isolated through microbiological methods, including Gram staining, oxidase test, Indol test, and oxidative-fermentative test. Then antibiotic susceptibility test was performed for imipenem, meropenem, gentamicin, amikacin, ciprofloxacin, and ceftazidime by disk diffusion method according to NCCLS (National Committee for Clinical Laboratory Standards) .Minimum inhibitory concentration (MIC) was done for determining imipenem-resistant strains Results: Antibiotic susceptibility test showed that resistance rates to imipenem, meropenem, gentamicin, amikacin, ciprofloxacin, and ceftazidime were 35%, 35%, 14%, 9%, 23% and 15%, respectively. Also, MIC test showed that 30 strains were resistant to imipenem, 27 to ceftazidime, 35 to cefepime, and 35 to ciprofloxacin. Conclusion: The results of this study indicated a high rate of antibiotics resistant of Pseudomonas aeroginosa strains to different antibiotic groups. Therefore, new and more effective methods should be found for controlling Pseudomonas infections and preventing the outbreak of its antibiotic-resistant strains.
Mana Shojapuor, Ghasem Mosayebi, Keyvan Ghasami, Ali Ghazavi, Abdolrahim Sadeghi,
Volume 15, Issue 4 (September 2012)
Abstract
Background: Multiple sclerosis (MS) is an autoimmune disease which demyelinates the central nervous system. Vitamin D, is a potential environmental factor which influences this disease. The majority of the biological activities of the polymorphism forms of vitamin D are done through its receptor gene (VDRG). The aim of this study was to examine the relationship between BsmI polymorphisms in VDRG and the incidence of MS. Materials and Methods: In this case-control study, the BsmI polymorphism in the VDRG was studied in 80 Iranian MS patients and 50 healthy controls of the same genetic background and age through polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method Results: There was a significant difference in the frequency of BsmI VDRG polymorphism genotypes between MS patients and controls (P=0.023). Conclusion: This study indicated that the VDRG BsmI polymorphism is associated with MS in this population.
Behroz Karimi, Mohamad-Sadegh Rajaei, Mohammad Javad Ganadzadeh, Masoumeh Mashayekhi, Mostafa Jahanbakhsh,
Volume 15, Issue 10 (March 2013)
Abstract
Background: The presence of nitrate in drinking water causes various health and environmental problems. The aim of this study was to evaluate the efficacy of nitrate reduction by Fe/H2O2 process and adsorption on activated carbon. Materials and Methods: This experimental study investigated nitrate oxidation by advanced oxidation process of Fe°/FeІІ/FeШ/H2O2 at pH 2-10, nitrate concentrations of 50-300 mg/L. After adjusting the pH, 0.5, 1, 2, 5, and 10 g/L values of GAC, PAC, H2O2/GAC, and Fe/H2O2/GAC together with H2O2 at retention times of 15, 30, 45, 60, and 90 minutes, respectively, were added and mixed. Results: At retention time of 10 minutes and 0.5 mL H2O2 and 1 g/L from Fe°, FeІІ, and FeІІІ, the removal efficacy was 88.5, 84 and 78%, respectively. At 50 mg/L nitrate and 0.5, 1, and 10 mg/L GAC concentrations, the removal efficacy was 56.5, 93.6, and 82.6%, respectively. The nitrate removal efficiency at pH=4 was approximately 50%, whereas at pH=3 with 30% efficacy, it increased to 80%. Conclusion: Modified Fe/H2O2 process with iron nano-particles and activated carbon adsorption can effectively reduce nitrate under optimal conditions. The use of activated carbon at a concentration of 1 g/L increased the removal efficiency of nitrate to 90%.
Hosein Honari, Iman Amlashi, Mohammad Ebrahim Minaee, Sadegh Safaee,
Volume 16, Issue 4 (7-2013)
Abstract
Background: Shigellosis is a major global issue of human health. To date, no effective vaccine has been found against Shigella. One of the major virulent factors in Shigella dysenteriae type 1 is Shigella enterotoxin or STx. STxB has immunogenic, adjuvant, or carrier properties. Vaccine candidate antigens can be coupled with this adjuvant for production of an appropriate vaccine. IpaD has a key role in invasion, virulence, and infection by Shigella.
Materials and Methods: In this study, the gene sequences of STXB and ipaD were obtained from gene bank and corresponding genes were prepared as synthetic construct and then transferred to E. coli BL21DE3. By PCR amplification and enzymatic digestion, protein expression levels were assessed. Its protein expression was confirmed by Western blot technique. After extraction by affinity chromatography, the recombinant protein was injected four times to guinea pigs. The pigs were, then, challenged by Shigella felexneri 2a and active toxin of E. coli O157:H7.
Results: The results showed that groups of guinea pigs challenged with 28×LD50 of toxin completely survived. Furthermore, guinea pigs were challenged by inducing Shigella felexneri 2a in their eyes. The results showed that the control pigs got cataracts, whereas the immune pigs were in health.
Conclusion: The findings of this study suggest that this recombinant protein is a good candidate for production of a recombinant vaccine against Shigella family.
Hosein Heydari , Mehdi Shafiee Ardestani, Rezvan Zabihollahi, Seyed Mehdi Sadat , Shiva Irani , Seyed Nezamedin Hoseini, Safieh Amini, Seyed Davar Syadat, Mohammad Sadegh Khosravi, Alireza Azizi Saraji, Pouneh Rahimi, Mohammad Reza Aghasadeghi,
Volume 16, Issue 6 (9-2013)
Abstract
Background: Due to the lack of efficient anti-HIV vaccine, anti-HIV pharmaceuticals play an important role in controlling HIV infection. Also significant rise in drug resistance and drug toxicity has caused increased interest in finding new anti-HIV agents. In this study, a nano-sized version of lamivudine based on PEGylated chitosan was synthesized.
Materials and Methods: In this research, nanoparticles of chitosan were efficiently PEGylated for increasing their stability in water and then the anti-HIV drug, lamivudine, was loaded on these PEGylated nanoparticles. After purification and lyophilization of new synthesized nanoparticle, the raw materials and final product were sampled and FTIR, HNMR and CHN analyses were done.
Results: Results of HNMR spectroscopy showed that chitosan nanoparticle was successfully PEGylated. HNMR data confirmed FTIR results and indicated that lamivudine was conjugated on chitosan nanoparticle. In addition, CHN analysis data also confirmed both HNMR and FTIR data, and demonstrated that a high yield of chitosan nanoparticle PEGylation (approximately 97%) was done and illustrated a high capacity of lamivudine conjugation on nano-sized PEGylated chitosan (30% W/W chitosan).
Conclusion: In this study, lamivudine drug was successfully synthesized, based on PEGylated chitosan nanoparticle.
Marjan Mojtabavi Naeini, Sadegh Vallian, Morteza Hashemzadeh Chaleshtori,
Volume 16, Issue 7 (10-2013)
Abstract
Background: SLC26A4 gene mutations are the second currently identifiable genetic cause of autosomal recessive non syndromic hearing loss (ARNSHL) after GJB2 mutations. In databases, several potential STR markers related to this region have been introduced. In this investigation, the identity and informativeness of D7S2459 CA repeat STR marker in SLC26A4 gene region was examined in five ethnic groups of the Iranian population.
Materials and Methods: The research study was accomplished by genotyping the locus in 165 individuals of five different ethnic groups including Fars, Azari, Torkaman, Gilak and Arab using polymerase chain reaction (PCR) followed by polyacrylamide gel electrophoresis (PAGE) and fluorescent capillary electrophoresis. In this study, results were analyzed by GeneMarker HID Human STR Identity software, GenePop program and Microsatellite Tools software.
Results: Analysis of the allelic frequency revealed the presence of 8 alleles for D7S2459 marker in the Iranian population. Among all, allele 148bp at the D7S2459 locus with 31% frequency was the most frequent. The Azari ethnic with 84.8% observed heterozygosity was the highest among all ethnic groups. Finally, analysis of PIC value revealed that D7S2459 marker could be considered as a highly informative marker in each ethnic of the Iranian population (PIC value above 0.7).
Conclusion: Our data suggested that D7S2459 could be introduced as a highly informative marker in molecular diagnosis of SLC26A4 based ARNSHL by Linkage analysis.
Nahid Bijeh, Sadegh Abbasian,
Volume 16, Issue 7 (10-2013)
Abstract
Background: Interleukin-1&beta (IL-1&beta) as a cytokine act in relationship to development of obesity and Insulin resistance. purpose of the study was compare the effects of Ramadan fasting (as dietary pattern) and aerobic exercise training on IL-1&beta and Insulin resistance in non-active obese subjects.
Materials and Methods: This study was semi-experimental research with repeated measures design. In this study, 18 obese male in Mashhad (between 40 to 50 years old and body mass index>30 Kg/m2) randomly was selected and after it was divided into fasting (N=9) and fasting and aerobic exercise training (N=9) groups. While the first group performed the fasting, then other group was performed aerobic exercise training for 27 sessions. They also performed the fasting. Finally, blood samples were taken for four different times.
Results: Statistic analysis shown that body fat percent of subjects was significantly decreased in both groups (p<0.05). Also, amount of insulin resistance was significantly decreased in fasting group (p<0.05). In addition, amount of IL-1&beta was significantly decreased in both groups(p<0.05).
Conclusion: Research results shown that levels of IL-1&beta decreased by fasting and especially by aerobic exercise training and it may lead to the decrease of insulin resistance in obese subjects.
Behrooz Karimi, Mohammad Sadegh Rajaei, Maryam Habibi, Mehri Esvand, Mehdi Abdollahy,
Volume 16, Issue 9 (12-2013)
Abstract
Background: Naphthalene is a polyaromatic hydrocarbon (PAHs) present in many water sediments. This study evaluated the performance of UV/H2O2 reaction to decompose naphthalene in the aqueous solution.
Materials and Methods: It was an experimental-laboratory study. A one liter cylindrical glass reactor was used for performing all degradation experiments. The radiation source was a low pressure mercury UV lamp emitting at 254 nm (30 W, UV-C) which was placed above a batch photoreactor for UV/H2O2 experiments and different concentrations of H2O2 (5, 10, 15, 20, 25 and 30 mg/L) were tested.
Results: In 15 mg/L naphthalene in UV/H2O2 system and reaction times 5, 10, 20, 30, 40, 50, 60, 100 and 120 minutes, 15, 28, 31 , 36, 42, 52, 56, 73 and 59.5% naphthalene removal efficiencies were observed and COD removal efficiencies in reaction times 5, 10, 20, 30, 40, 50, 60, 100 and 120 minutes, 22, 38, 45, 61.5, 67.5, 70, 80, 88.5 and 76 % were observed. When the initial pH values were 3, 4, 5, 6, 7,9, 10 and 12 the naphthalene removal efficiency was approximately 75.8, 63.4, 62, 58.5, 44.8, 35.8 and 30%, respectively, with UV/H2O2 system.
Conclusion: The experimental results of this study suggested that the dosages with 20 mg/L H2O2 at pH= 3 with 2.8 W/cm2 UV intensity (254 nm) provided the optimal operation conditions for the mineralization of naphthalene yielding a 73% mineralization efficiency after 100 minutes of reaction time.
Fatemeh Safi, Hormoz Haddad Larijani, Mehri Jamilian, Bahman Sadeghi,
Volume 16, Issue 9 (12-2013)
Abstract
Background: Today, ultrasonography has become the main tool used for the evaluation of fetal anomalies. The aim of this study was to evaluate fetal heart rate changes immediately after combined two- and 4-dimensional ultrasound.
Materials and Methods: This study was performed on 191 pregnant women aged 15 to 45 years old who were referred for 4-dimensional ultrasonography in summer 2013. Before the onset of 2-dimensional ultrasonography, baseline fetal heart rate was measured by ultrasound. At the same time, the maternal heart rate was recorded during one minute. Then, combined ultrasonography was performed and same parameters were recorded at the end.
Results: Maternal heart rate significantly decreased after combined ultrasonography (p=0.0001). Fetal heart rate did not differ before and after ultrasonography (p=0.693).
Conclusion: Four-dimensional ultrasonography has no effect on fetal heart as an indicator for evaluating the fetus temperature.
Habib Soheili, Parsa Yousefi Chaijan, Anita Alaghmand, Bahman Sadeghi Saddeh, Amin Tavasoli, Mahdyieh Naziri,
Volume 17, Issue 1 (4-2014)
Abstract
Background: Allergic rhinitis affects 40% of general population and has an increasing prevalence. Sleep disturbance is an important problem in individuals with allergic rhinitis. Recent studies have shown that 68% of cases with perennial rhinitis and 48% with seasonal rhinitis have impaired sleep.
Materials and Methods: In this case-report study, 33 children with allergic rhinitis aging 6-18 years entered the study. Thirty five children without allergic rhinitis entered the study as control group. A questionnaire containing demographic data and types of sleep disorders filled for every child.
Results: Except respiratory disorder, there was no other significant difference between groups in any sleep disorder. Sixteen children (48.5%) in case group has respiratory disorder while none of control children were involved (P=0.0).
Conclusion: Nasal congestion is the main factor involved in sleep impairment in children with allergic rhinitis. Therefore, it seems that it is the first symptom to be treated.
Kavoos Shahsavari Nia, Farzad Rahmani, Hanieh Ebrahimi Bakhtavar, Ali Akbar Taher Aghdam, Elyar Sadeghi Hokmabadi, Armita Massood,
Volume 17, Issue 1 (4-2014)
Abstract
Background: Sudden visual loss is one of the emergent problems that it may be a sign of a life-threatening disease. It should be quickly evaluated and identified the treatable causes.
Case report: A young man without any history of certain disease was referred to the emergency department with complaints of sudden blindness. He was presented with fever, coriza symptoms and progressive blurring of vision that ultimately led to his visual loss. After carefully evaluation, finally suspected diagnosis of acute fulminant multiple sclerosis was made.
Discussion: Multiple sclerosis is a chronic inflammatory disease that is associated with acute attacks of neurological dysfunction. Some of these attacks are an emergent situation and need to early detection and treatment. There is a variant of Multiple sclerosis that called Acute Fulminant Multiple sclerosis which can cause sudden visual loss.
