Fateme Halalkhor, Ameneh Poorrahim, Marefat Siahkouhian,
Volume 26, Issue 5 (December & January 2023)
Abstract
Introduction: Anti-cytokine considerations in COVID-19 patients can play a significant role in preventing death, therefore, physical activity by reducing risk factors, as well as saffron with anti-inflammatory and antioxidant properties, are considered as anti-cytokine solutions. Therefore, the purpose of this research is to investigate the effect of saffron supplementation and endurance training on the concentration of interleukin-6, interleukin-10 and L-cysteine in outpatients with coronavirus.
Methods: The statistical population of this research is outpatients with coronavirus, 36 of whom were randomly selected. Cytokines and L-cysteine were measured using a special kit and ELISA method. The research hypotheses were checked at a significance level of P < 0.05 using ANOVA test with repeated measurements with between-group factor.
Results: The results showed that endurance activity and saffron supplementation caused a significant decrease in IL-6 levels and the ratio of interleukin 6 to interleukin 10 (P ≥ 0.05). Also, endurance activity along with saffron supplementation caused a significant increase in serum L-cysteine concentration (P = 0.035). The results showed that there is no interaction effect between the measurement stages and the group, as well as intra-group and inter-group differences in interleukin-10 variables (P = 0.511).
Conclusions: The levels of IL-6 and IL-10 decrease due to saffron supplementation and endurance training, and the amount of L-cysteine increases, which helps the recovery of COVID-19 patients.
