Showing 10 results for Zarei
Parvin Zareian,
Volume 12, Issue 1 (5-2009)
Abstract
Background: The role of sex hormones in pain perception and the effect of stress on reproductive system have not been determined yet. The present study investigated the effects of acute and chronic restraint stress on nociception and sex hormones concentration in rats. Methods and Materials: This experimental study was carried out with 47 male and female rats which ranged in weight from 170-230 gr. In order to transmit stress to the rats, they were initially exposed to acute restraint stress (1h) and chronic stress (for two weeks-1h/day). Then they were submitted to tail flick test for nociception evaluation. Sex hormones serum level was measured by radioimmunoassay method. Results were analyzed with Mann-Whitney and Kruskal-Wallis tests. Results: In male and female rats, acute restraint stress had significant increment in latency in the tail flick test. Chronically stress in male rats, was not significant effect on latency time. Chronically stress in females responded to restraint stress with an increase in tail flick latency. Both acute and chronic restraint stress reduced testosterone level in the male rats. In the female rats, only acute restraint stress significantly decrease plasma estradiol level. Restraint stress did not effect on testosterone concentration level in the female and estradiol level in the male rats. Conclusion: Acute restrain stress decrease nociceptive and sex hormon levels in male and female rate but, chronic restraint stress causes sex dependent response.
Ali Zarei, Saeed Ashtiyani, Fatemeh Rasekh, Ali Asghar Mohamadi, Ayob Gabari,
Volume 14, Issue 2 (5-2011)
Abstract
Background: Hyperlipidemia is an important risk factor for cardiovascular diseases. In this study, the effects of physalis alkekengi extract on the levels of cholesterol, low density lipoproteins (LDL), high density lipoproteins (HDL), and triglycerides (TG) were evaluated.
Materials and Methods: In this experimental study, fifty adult male Wistar strain rats were selected and divided into five groups of ten: Control group with a normal diet, control group with a high fat diet receiving interpritoneal injection of saline for 21 days, and treatment groups with fatty diets which received maximum (0.1 g/kg), moderate (0.2 g/kg), and minimum (0.4 g/kg) dose interpritoneal injections of the extract. After this period, blood sampling was done and the obtained results were analyzed through SPSS software.
Results: According to the obtained results, LDL and cholesterol concentrations decreased significantly (P<0.05), whereas HDL and TG plasma concentrations did not reveal any significant changes.
Conclusion: The findings of this study show that such changes are mainly due to the lycopene existing in the plant. Lycopene is a strong antioxidant which inhibits the production of LDL and presumably increases the excretories through releasing cholesterol therefore, it reduces blood cholesterol level and controls cholesterol synthesis.
Saeed Changizi Ashtiyani, Ali Zarei, Mehrdad Shariati, Jabary, Hasan Ghasemi,
Volume 14, Issue 5 (11-2011)
Abstract
Background: Physalis Alkekengi is a perennial plant with a creeping and ryzumy stem belonging to the solanaceae family. This study investigates the possible effects of Physalis Alkekengi on plasma concentrations of some biochemical factors.
Materials and Methods: Fifty male Wistar rats weighing an average of 190 ± 5 g were divided into five groups of ten: Control group without receiving any substances, control group with 2.0 ml/dl administration of the solvent, and three experimental groups receiving 0.4 (maximum), 0.2 (medium), and 0.1 (minimum) g/kg intra-peritoneal (IP) injections of the drug. The intra-peritoneal (IP) injection of the drug was done for 14 days and after this period, for conducting lab tests, blood sampling was done and the results were analyzed through ANOVA and Tukey test.
Results: According to the results, protein and albumin plasma concentrations showed a significant increase (P<0.05) while creatinine plasma concentration, bilirubin, and urea nitrogen (BUN) did not reveal any significant changes.
Conclusion: This family of plants contains significant amounts of glucocorticoids, such compounds are likely to increase liver and plasma proteins. In addition, due to the presence of compounds, such as physaline, vitamin C, and albumin, this extract is likely to increase blood pressure and, eventually, increase glomerulic refinement and diuretic properties therefore, the absence of significant increases in plasma concentrations of the substances produced by metabolism in plasma seems reasonable
Amir Almasi-Hashiani, Soheila Zareifar, Seyed Hamid Hosseini, Aziz Dehghan,
Volume 15, Issue 2 (June-July 2012)
Abstract
Background: Leukemia is the most common type of cancer in children which its relapse decreases the patients’ survival rate. The aim of this study was to determine the risk factors involved in leukemia relapse in patients in Shahid Faghihi Hospital, Shiraz, during 2004-2009 years.
Materials and Methods: In this retrospective cohort study, 280 patients with acute lymphoblastic leukemia and acute myeloid leukemia were included. Patient characteristics were analyzed with respect to their association with recurrence through Chi-square test, Fisher’s exact test, and logistic regression model using SPSS software version 16 (P-value<0.05).
Results: Logistic regression model revealed a statistically significance relationship between age and recurrence of the disease (odds ratio (OR) = 0.35, 95% confidence interval (CI) = 0.15-0.82), odds ratio of relapse in the 5-10 years old age group was 0.35 times more than the 0-5 years old age group (p=0.01).
Conclusion: Noticing the greater likelihood of relapse in 0-5 years old age group compared with the 5-10 years old age group, more attention and better follow-up for decreasing the side effects of the disease and enhancing the survival rate of the 0-5 y/o age group are recommended.
Ali Zarei, Mehrdad Shariati, Shahnaz Shekar Forosh , Saeid Ashtiyani, Fateme Rasekh,
Volume 15, Issue 7 (December 2012)
Abstract
Background:Noticing the side effects associated with chemical drugs, using natural medicinal plants has gained more prominence recently. Physalis alkekengi extract is a medicinal plant belonging to Solanaceae family which similar to most drugs used in traditional medicine, despite possessing a multitude of medicinal properties, has not received sufficient attention. The aim of the present study was to briefly review the effects of Physalis alkekengi extract on the concentration of thyroid hormones, blood cholesterol, some plasma biochemical factors, liver function, immune system, and sexual hormones. Due to the extensive usage of Physalis alkekengi extract in traditional medicine, determining its advantages and possible side effects is of great physiologic and pharmacologic significance. Physalis alkekengi extract due to the presence of such effective substances as alkaloids, lycopene, glucocorticoids, alcoholic agents, and a large amount of vitamin C as well as antioxidant properties can play a significant role in changes in body homeostasis. This study dealt with the function and effect of Physalis alkekengi extract on different body organs through using proper keywords and extensive online search through electronic databases and credible sources. The results of this mini-review showed that Physalis alkekengi extract can bring about various significant changes in different body organs that have not been properly recognized. Therefore, further and more extensive studies should be done on this plant.
Majid Motamedzade , Ali Dormohammadi, Hosein Amjad Sardrodi , Esmaeil Zarei , Reza Dormohammadi, Masoud Shafii Motlagh,
Volume 16, Issue 6 (9-2013)
Abstract
Background: Load lifting is the most stressful activity of the Manual Material Handling and can trigger of work-related musculoskeletal disorders of workers. Purposes of this study are determining the prevalence of musculoskeletal disorders, assessment lifting tasks by NIOSH lifting equation method, ergonomic design and assessment of its effectiveness.
Materials and Methods: This analytical and interventional study was performed on 30 workers in a Porcelain Health Manufacturing industry in Hamadan. Assessment of lifting tasks by NIOSH lifting equation and determining the prevalence of musculoskeletal disorders by Nordic questionnaire was conducted. Then, construction steps and determination of the effectiveness of ergonomic design was conducted.
Results: The results showed that the most frequent musculoskeletal disorders related to back. Results of the lifting index (LI) showed that the risk of lifting load in before intervention is high (greater than 3). This value after the conducting of ergonomic intervention (load-carrying cart) decreased to moderate level (between 1 to 3). The relationship of risk average amount before and after interventions were significant (p<0.001).
Conclusion: Load-carrying cart designed with shelves capable of moving vertically up and down has considerable role in safe making of lifting tasks and probability of reduce the prevalence of musculoskeletal disorders and lumbar injuries will bring in the near future.
Saeed Changizi-Ashtiyani, Majid Ramezani, Hossein Poorcheraghi, Seyed Mohammad Afzali, Parand Pirouzi, Sina Atashi, Ali Zarei,
Volume 22, Issue 5 (11-2019)
Abstract
Background and Aim Among the plants with multiple healing properties and a long and common history of use in Iranian traditional medicine, is dog-rose plant with the scientific name of “Rosa canina” that belongs to the Rosaceae family. This study aimed to review the effectiveness of Rosa canina in treatment of different body organs and tissues and emphasizes its therapeutic mechanism.
Methods & Materials This is a review study. About 176 papers published from 2010 to 2018 were extracted from PubMed, Science Direct, Scopus, Google Scholar, Ovid, MagIran, and SID databases using related keywords and entered into study.
Ethical Considerations Ethical issues (including plagiarism, misconduct, data fabrication, falsification, double publication or submission, redundancy) have been completely observed by the authors.
Results Different studies had indicated the importance of Rosa canina as a medicinal plant protecting liver, lowering glucose and lipid levels, and having antioxidant and anti-inflammatory properties. The highest flavonoid activity in the Rosaceae family is related to Rosa canina. The use of herbal extracts in the treatment of common diseases, such as diabetes, fatty liver, urinary tract and Alzheimer's, has been recommended.
Conclusion High qualitative and quantitative diversity of effective ingredients, ease of access, absence of adverse effects of consumption and endemic nature of Rosa canina plant make it necessary to use it for the control and treatment of common human diseases.
Azar Hamidi, Amir Rashidlamir, Rambod Khajei, Mehdi Zarei, Ahmad Zendedel,
Volume 23, Issue 3 (August & September 2020)
Abstract
Background and Aim: Coronary Heart Disease (CAD) is one of the most important causes of mortality. Exercise activities after coronary artery bypass surgery increase the density of myocardial capillaries called angiogenesis and improve cardiovascular function. The aim of the present study was to determine the effect of aerobic-resistance training on plasma basic fibroblast grown factor levels in post-coronary artery bypass grafting patients.
Methods & Materials: The sample consisted of 30 men aged 45-60 years who underwent bypass surgery. They were randomly divided into experimental (n=15) and control (n=15) groups. The experimental group performed aerobic resistance training for eight weeks (3 sessions per week) and the control group did not. Blood samples were taken 24 hours before the start of the first training session and 48 hours after the last training session while all subjects were fasting. In vitro ELISA method was used to measure BFGF. Independent and paired t-test and Shapiro-Wilk test were used to analyze the data at the significant level of 0.05 in SPSS v. 21.
Ethical Considerations: This study was registered (Ethics Code: IR.IAU.NEYSHABUR.REC.1398.01) in the Ethics Committee of Islamic Azad University, Neishabour Branch, and with Clinical Trial Code: IRCTID:IRCT20191228045919N1.
Results: Eight weeks of aerobic-resistance training significantly increased bFGF levels in the exercise group compared to the control group (P=0.002). Also, pre and post changes in the experimental group showed a significant increase in plasma bFGF levels (P=0.002), which was not significant in the control group (P=0.758).
Conclusion: According to the results, it may be concluded that combined (aerobic resistance) exercise may increase angiogenesis and capillary density in post-CABG patients by increasing plasma bFGF levels
Mohammad Ranjbarian, Korosh Etemad, Fatemeh Zarei, Rozita Farhadi, Jalaledin Sa´di,
Volume 24, Issue 1 (April & May 2021)
Abstract
Background and Aim: It is almost impossible to imagine life without electromagnetic waves. Such waves play a key role in the function of melatonin and create numerous diseases.
Methods & Materials: This descriptive-analytical study was conducted on 230 kV substations in Golestan Province, Iran in 2016. In total, 44 workers of electrical substations (the case group) and 23 workers of healthcare centers (the control group) with 24-hour shift works were enrolled in this study.
Ethical Considerations: This study was approved by the Ethics Committee of Shahid Beheshti University Medical Sciences( Code: IR.SBMU.THNS.REC.1395.9).
Results: The obtained data suggested that 100% of the electric field intensity and the magnetic flux density measured at the substations were within the permissible range of occupational exposure. The mean level of melatonin in the case group was lower than that in the control group; however, no significant difference was observed in this regard (P=0.761). Additionally, there was no significant difference between melatonin level and age (P=0.381), work experience (P=0.213), job groups (P=0.515), and employee activity area (P=0.482).
Conclusion: According to this study, no significant relationship was observed between electromagnetic waves and melatonin levels. Moreover, electromagnetic waves were within the permissible exposure. Thus, electromagnetic waves did not affect the level of melatonin hormone in male employees of 230 kV substations in Golestan Province. However, there was a decrease in the case group, compared to the controls. Therefore, definite comments require further investigation.
Manijeh Zarei Mahmood Abadi, Talieh Zarifian, Dr Robab Teymouri,
Volume 24, Issue 4 (October & November 2021)
Abstract
Background and Aim: Acquisition skill in sentence producing is one of the criteria for speech development. By developing and increasing the age, we are witnessing the emergence of compound sentences in speech. Clinical treatments for language disorders in Iran are mostly based on the experiences of Speech Language Therapists or in accordance with English language norms. We need to examine how the length of utterance and compound sentences develop in Persian. The study aimed to report the development of compound sentences and Mean Length of Utterance (MLU) for a Persian-speaking child from 15 to 34 months.
Methods & Materials: In this longitudinal case report, based on Developmental-Descriptive model, MLU and emergence of simple compound sentences of a Persian speaking girl sampled and described from 15 to 34 months by daily scripting. R software version 4.0.2 was used for data analysis. Correlation of age with linguistic variables through Pearson correlation coefficient was evaluated.
Ethical Considerations: In this paper, the principles of publication ethics were considered.
Results: At the age of 21 months and 13 days, the child uttered her first simple two-word sentence, and at the age of 26 months and 29 days, she used a four-word compound sentence. With the emergence of compound sentences, the increase in the MLU has gained considerable speed. In a few days, we see the addition of a unit to the length of the sentence (word). There was a significant relationship between the MLU and age (r=0.925, P=0.001), Mean length of sentence and number of words in Persian speaking child (r=0.910, P=0.002) and total number of words and age (r=0.928, P<0.001).
Conclusion: Although several longitudinal studies have been conducted on the development of MLU and number of words in other languages, similar studies are rare in Persian. It is important to conduct studies of this type in order to make cross-linguistic comparisons and to study the linguistic universality and language specificity. By increasing age, we see an increase in the number of words in a child's vocabulary, the emergence of compound sentences, and an increase MLU. At 27 to 28 months, there is a dramatic change in the development expressive language as the compound sentences appear. It seems that emergence of compound sentences in the language output, also plays a significant role in increasing the MLU and can be considered in clinical language assessments.
