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Introduction: Depression is one of the most common affective disorders, and in addition to different neurotransmitters and life events, various internal stressors such as blood glucose, cholesterol, triglyceride and other factors are responsible for it. Considering hyperglycemia as a possible risk factor of this disorder and inconsistency in results of previous studies, we decided to assess the relationship between different levels of HbA1C and major depression. Materials and Methods: This is a cross-sectional analythical study that is carried out on 134 samples. They were chosen randomly among patients with type2 diabetes reffering to Vali-e-Asr hospital. The patients were divided into 2 groups on the basis of their HbA1C test results patients with HbA1C less than 7% (group A), consisting 55 persons and patients with HbA1C more than 7% and equal to it (group B), including 79 persons. Participants were assessed by Hamilton scale of depression. The relation between HbA1C levels and major depression in these 2 groups was assessed using Chi square and Mann Whitney U tests. Results: We found that 40% of depressed patients had HbA1C level lower than 7% and 60% of them had HbA1C level higher than 7%. No significant correlation was found between HbA1C and major depression. But the duration of disease, using Insulin and being hypertensive simultaneously was correlated to major depression in this study. Conclusion: This study indicates that uncontrolled diabetes and high level of blood glucose is cosidered of less importance as an undelying mechanism of depression in patients with type 2 diabetes.

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Background:Today, in spite of quick and amazing human advancements in prevention treatment, and control of diseases and their positive effects on the community, lack of reliance on the instructions of prophets on spirituality and ethics of human relationships has led to health, social, ethical, and environmental crises that have resulted in spread of emerging diseases such as AIDS. Therefore, the way out of this crisis is the return to the instructions of prophets and religions, especially Islam. This article explains the role of Islam instructions in achieving millennium development goals in the fight against malaria and AIDS. Materials and Methods: In this review article, through access to reliable sources in the form of a descriptive article, practical strategies of Islam for achieving millennium development goals for fighting diseases, AIDS, and malaria are investigated. In so doing, by applying appropriate keywords to electronic and manual search in reliable Islamic and medical resources, data were collected and the central research question was addressed. Results: Based on the results of the reviewed studies, instructions and ideas of Islam on reconstructing the environment, preservation of natural resources, observing personal health, priority of health to treatment, abstinence from risky sexual behaviors, and so forth have practical implications for malaria and AIDS control and prevention so that if there had been commitment to Islam, AIDS as an emerging disease might never have developed. Conclusion: Noticing the availability of resources and instructions in Islam on health and medicine for prevention and fight against diseases, such ideas can be utilized for preventing the emergence and development of other new diseases. Hence, Islamic instructions can be presented to the world as practical strategies for achieving millennium development goals.