Journal of Arak University of Medical Sciences

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Goiter Survey and Urinary Iodine Concentration in School Children Aged 8 to 10 Year of Markazi Province in 1996

Fereydoun Azizi, Robabeh Sheikholeslam, Parvin Mirmiran, Gita Abdolhosini, Masoud Kimiagar, Hossein Malekafzali,
Volume 4, Issue 3 (Autumn 2001)

Abstract

Introduction: Iodine deficiency disorders (IDD) is a worldwide health problem. Many parts of the Islamic republic of Iran had been known as areas of endemic goiter. IDD was accepted as a priority health problem in the country and a National IDD Council was formed in 1989.
Material and Method: One of the main strategies of National Council for IDD control was to provide at least 150mg of iodine per day to the entire population through making available iodized salt. This study was performed to evaluate the National IDD council program in 1996, in rural and urban areas of Markazi province, 1300 school children, aged 8 to 10 years, including 50% boys, were selected through random sampling Grading of goiter was performed according to WHO. Classification, Serume, T3, T4 and TSH were measured by RIA and urinary iodine by digestion method.
Results: The mean of serume T3, T4 and TSH were: 10±2.0 μg/dl, 160±28 ng/dl and 2.3±1.3 μIu/ml respectively. There were no differences between males and females and school children of rural or urban areas. Four person had serum T4 more than 12.5μg/dl. The mean urinary iodine was 16mg/dl in entire population. 75% had urinary iodine more than 10mg/dl. Only 11% had urinary iodine less than 5μg/dl. Total prevalence of goiter was 35% (36% in girls and 34% in boys).
Conclusion: Based on the available data, seven years after distribution of iodized salt, urinary iodine of school children of Markazi province does not show iodine deficiency. However goiter is still endemic in Markazi province.

Evaluation of iodine sufficiency in school children of Markazi province, 2001

Dr Mosen Naghavi, Dr Ali Akbar Rezai Ashtiani, Dr Robabeh Sheikholeslam, Ms Naghmeh Tashakori, Dr Sepideh Hajforoush, Dr Fereydun Azizi,
Volume 8, Issue 4 (12-2005)

Abstract

Introduction: Markazi province was one of the regions with endemic goiter in Iran. Following initiation of iodine deficiency control program in 1989, production, distribution and consumption of iodized salt begun. This survey was conducted in the frame work of national monitoring survey in 2001 to find the prevalence of goiter and urinary iodine level in order to evaluate the iodine status of school age children in Markazi province.

Materials and Methods: 1200 school children (600 boys and 600 girls), aged 7-10 years, were selected randomly from all regions of Markazi province. The grade of Goiter was determined according to WHO classification and urinary iodine content was estimated using the digestion method in one tenth of the these children. Data was analyzed using T, Chi square and Pearson tests.

Results: Total Goiter rate was 4.4% (4.4% in girls and 4.4% in boys). Urinary iodine median was 16.7 µg/dl. Urinary iodine was above 10 µg/dl in 81.2% and less than 5 µg/dl in 9.2% of samples. No one had urinary iodine below 2 µg/dl.

Conclusion: It is concluded that the rate of Goiter in Markazi province has decreased significantly since 1986 and urinary iodine levels in school children are indicative of adequate iodine intake. Therefore Markazi province can be considered as an “iodine deficiency free” zone.

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